Multifunctionality of a picornavirus polymerase domain: Nuclear localization signal and nucleotide recognition

Journal of Virology

Volumn 89, Issue 13, 2015, Pages 6848-6859

  Ferrer Orta, Cristina ^a   De La Higuera, Ignacio ^b,d   Caridi, Flavia ^b   Sánchez Aparicio, María Teresa ^b   Moreno, Elena ^b   Perales, Celia ^b,c   Singh, Kamalendra ^d,e   Sarafianos, Stefan G ^d,e   Sobrino, Francisco ^b   Domingo, Esteban ^b,c   Verdaguer, Nuria ^a  

^a INSTITUT DE BIOLOGIA MOLECULAR DE BARCELONA   (Spain)

^b CENTRO DE BIOLOGÍA MOLECULAR SEVERO OCHOA   (Spain)

^c INSTITUTO DE SALUD CARLOS III   (Spain)

^d UNIVERSITY OF MISSOURI   (United States)

^e University of Missouri   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; ANTIVIRUS AGENT; DNA POLYMERASE; GLUTAMIC ACID; LYSINE; NUCLEOTIDE; RIBAVIRIN MONOPHOSPHATE; UNCLASSIFIED DRUG; MUTANT PROTEIN; NUCLEAR LOCALIZATION SIGNAL; PROTEIN BINDING; RNA; VIRAL PROTEIN; VIRUS ANTIGEN; VIRUS-INFECTION-ASSOCIATED ANTIGEN, FOOT-AND-MOUTH DISEASE VIRUS;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ENZYME STRUCTURE; FOOT AND MOUTH DISEASE VIRUS; MUTANT; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; PRIORITY JOURNAL; PROTEIN MOTIF; PROTEIN RNA BINDING; RNA REPLICATION; WILD TYPE; CHEMISTRY; ENZYMOLOGY; GENETICS; METABOLISM; MISSENSE MUTATION; MOLECULAR MODEL; PROTEIN CONFORMATION; X RAY CRYSTALLOGRAPHY;

FOOT-AND-MOUTH DISEASE VIRUS; PICORNAVIRIDAE;

AMINO ACID SUBSTITUTION; ANTIGENS, VIRAL; CRYSTALLOGRAPHY, X-RAY; FOOT-AND-MOUTH DISEASE VIRUS; MODELS, MOLECULAR; MUTANT PROTEINS; MUTATION, MISSENSE; NUCLEAR LOCALIZATION SIGNALS; NUCLEOTIDES; PROTEIN BINDING; PROTEIN CONFORMATION; RNA; VIRAL NONSTRUCTURAL PROTEINS;

EID: 84930884570     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.03283-14     Document Type: Article

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