Structural basis for proteolysis-dependent activation of the poliovirus RNA-dependent RNA polymerase

EMBO Journal

Volumn 23, Issue 17, 2004, Pages 3462-3471

  Thompson, Aaron A ^a   Peersen, Olve B ^a  

^a Department of Environmental and Radiological Health Sciences   (United States)

Author keywords

Allostery; Poliovirus; Polymerase; Proteolysis; Replication

Indexed keywords

RNA DIRECTED RNA POLYMERASE;

ALLOSTERISM; AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME SUBSTRATE COMPLEX; NONHUMAN; POLIOMYELITIS VIRUS; PRIORITY JOURNAL; PROTEIN DEGRADATION; SIGNAL TRANSDUCTION; VIRUS REPLICATION;

CRYSTALLOGRAPHY, X-RAY; DNA-DIRECTED DNA POLYMERASE; ENDOPEPTIDASES; ENZYME ACTIVATION; ENZYME PRECURSORS; GUANOSINE TRIPHOSPHATE; HYDROGEN BONDING; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; POLIOVIRUS; PROTEIN CONFORMATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECOMBINANT PROTEINS; RNA REPLICASE;

POLIOVIRUS;

EID: 4644238112     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.emboj.7600357     Document Type: Article

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