Enterovirus 71 VPg uridylation uses a two-molecular mechanism of 3D polymerase

Journal of Virology

Volumn 86, Issue 24, 2012, Pages 13662-13671

  Sun, Yuna ^a   Wang, Yaxin ^b,d,e   Shan, Chao ^c   Chen, Cheng ^b   Xu, Peng ^b   Song, Mohan ^e   Zhou, Honggang ^d,e   Yang, Cheng ^d,e   Xu, Wenbo ^b   Shi, Pei Yong ^f   Zhang, Bo ^c   Lou, Zhiyong ^b  

^a INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

^b TSINGHUA UNIVERSITY   (China)

^c WUHAN INSTITUTE OF VIROLOGY   (China)

^d Tianjin Joint Academy of Biomedicine and Technology   (China)

^e NANKAI UNIVERSITY   (China)

^f WADSWORTH CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NONSTRUCTURAL PROTEIN 3B; TYROSINE; UNCLASSIFIED DRUG; URIDINE PHOSPHATE; VIRUS ENZYME; VIRUS PROTEIN; VIRUS RNA;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING SITE; CATALYSIS; CONTROLLED STUDY; ENTEROVIRUS 71; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME LOCALIZATION; ENZYME MECHANISM; ENZYME METABOLISM; GENETIC COMPLEMENTATION; IN VITRO STUDY; MOLECULAR MECHANICS; MOLECULAR MODEL; NONHUMAN; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN PROCESSING; PROTEIN STABILITY; RNA REPLICATION; RNA TRANSLATION; THREE DIMENSIONAL IMAGING; URIDYLATION; VIRUS REPLICATION;

AMINO ACID SEQUENCE; ANIMALS; CERCOPITHECUS AETHIOPS; DNA-DIRECTED RNA POLYMERASES; ENTEROVIRUS A, HUMAN; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; SEQUENCE HOMOLOGY, AMINO ACID; URIDINE MONOPHOSPHATE; VERO CELLS; VIRAL PLAQUE ASSAY; VIRUS REPLICATION;

HUMAN ENTEROVIRUS 71; PICORNAVIRIDAE;

EID: 84870666504     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01712-12     Document Type: Article

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