-
1
-
-
37549035027
-
Diabetic nephropathy: Mechanisms of renal disease progression
-
Maywood
-
Kanwar, Y.S.; Wada, J.; Sun, L.; Xie, P.; Wallner, E.I.; Chen, S.; Chugh, S.; Danesh, F.R. Diabetic nephropathy: mechanisms of renal disease progression. Exp. Biol. Med. (Maywood)., 2008, 233(1), 4-11.
-
(2008)
Exp. Biol. Med.
, vol.233
, Issue.1
, pp. 4-11
-
-
Kanwar, Y.S.1
Wada, J.2
Sun, L.3
Xie, P.4
Wallner, E.I.5
Chen, S.6
Chugh, S.7
Danesh, F.R.8
-
2
-
-
53849124336
-
Regulation and consequences of differential gene expression in diabetic kidney disease
-
Murphy, M.; Crean, J.; Brazil, D.P.; Sadlier, D.; Martin, F.; Godson, C. Regulation and consequences of differential gene expression in diabetic kidney disease. Biochem. Soc. Trans., 2008, 36(Pt 5), 941-945.
-
(2008)
Biochem. Soc. Trans.
, vol.36
, pp. 941-945
-
-
Murphy, M.1
Crean, J.2
Brazil, D.P.3
Sadlier, D.4
Martin, F.5
Godson, C.6
-
3
-
-
80052520550
-
Kidney biopsy in patients with diabetes mellitus
-
Haider, D.G.; Peric, S.; Friedl, A.; Fuhrmann, V.; Wolzt, M.; Horl, W.H.; Soleiman, A. Kidney biopsy in patients with diabetes mellitus. Clin. Nephrol., 2011, 76(3), 180-185.
-
(2011)
Clin. Nephrol.
, vol.76
, Issue.3
, pp. 180-185
-
-
Haider, D.G.1
Peric, S.2
Friedl, A.3
Fuhrmann, V.4
Wolzt, M.5
Horl, W.H.6
Soleiman, A.7
-
4
-
-
79751477368
-
A glimpse of various pathogenetic mechanisms of diabetic nephropathy
-
Kanwar, Y.S.; Sun, L.; Xie, P.; Liu, F.Y.; Chen, S. A glimpse of various pathogenetic mechanisms of diabetic nephropathy. Annu. Rev. Pathol., 2011, 6, 395-423.
-
(2011)
Annu. Rev. Pathol.
, vol.6
, pp. 395-423
-
-
Kanwar, Y.S.1
Sun, L.2
Xie, P.3
Liu, F.Y.4
Chen, S.5
-
5
-
-
34047251834
-
Histopathology of diabetic nephropathy
-
Fioretto, P.; Mauer, M. Histopathology of diabetic nephropathy. Semin. Nephrol., 2007, 27(2), 195-207.
-
(2007)
Semin. Nephrol.
, vol.27
, Issue.2
, pp. 195-207
-
-
Fioretto, P.1
Mauer, M.2
-
6
-
-
10644277302
-
New insights into the pathophysiology of diabetic nephropathy: From haemodynamics to molecular pathology
-
Wolf, G. New insights into the pathophysiology of diabetic nephropathy: from haemodynamics to molecular pathology. Eur. J. Clin. Invest., 2004, 34(12), 785-796.
-
(2004)
Eur. J. Clin. Invest.
, vol.34
, Issue.12
, pp. 785-796
-
-
Wolf, G.1
-
7
-
-
0037407520
-
Extracellular matrix metabolism in diabetic nephropathy
-
Mason, R.M.; Wahab, N.A. Extracellular matrix metabolism in diabetic nephropathy. J. Am. Soc. Nephrol., 2003, 14(5), 1358- 1373.
-
(2003)
J. Am. Soc. Nephrol.
, vol.14
, Issue.5
, pp. 1358-1373
-
-
Mason, R.M.1
Wahab, N.A.2
-
8
-
-
84873021479
-
Diabetic nephropathy and extracellular matrix
-
Kolset, S.O.; Reinholt, F.P.; Jenssen, T. Diabetic nephropathy and extracellular matrix. J. Histochem. Cytochem., 2012, 60(12), 976- 986.
-
(2012)
J. Histochem. Cytochem.
, vol.60
, Issue.12
, pp. 976-986
-
-
Kolset, S.O.1
Reinholt, F.P.2
Jenssen, T.3
-
9
-
-
84858307317
-
Signaling mechanisms in the regulation of renal matrix metabolism in diabetes
-
Mariappan, M.M. Signaling mechanisms in the regulation of renal matrix metabolism in diabetes. Exp. Diabetes Res., 2012, 2012, 749812.
-
(2012)
Exp. Diabetes Res.
, vol.2012
, pp. 749812
-
-
Mariappan, M.M.1
-
10
-
-
0033934431
-
Expression of decorin, biglycan, and collagen type I in human renal fibrosing disease
-
Stokes, M.B.; Holler, S.; Cui, Y.; Hudkins, K.L.; Eitner, F.; Fogo, A.; Alpers, C.E. Expression of decorin, biglycan, and collagen type I in human renal fibrosing disease. Kidney Int., 2000, 57(2), 487- 498.
-
(2000)
Kidney Int
, vol.57
, Issue.2
, pp. 487-498
-
-
Stokes, M.B.1
Holler, S.2
Cui, Y.3
Hudkins, K.L.4
Eitner, F.5
Fogo, A.6
Alpers, C.E.7
-
11
-
-
84879493776
-
GLUT1 regulation of the prosclerotic mediators of diabetic nephropathy
-
Heilig, C.W.; Deb, D.K.; Abdul, A.; Riaz, H.;James, L.R.; Salameh, J.; Nahman, N.S Jr. GLUT1 regulation of the prosclerotic mediators of diabetic nephropathy. Am. J. Nephrol., 2013, 38(1), 39-49.
-
(2013)
Am. J. Nephrol.
, vol.38
, Issue.1
, pp. 39-49
-
-
Heilig, C.W.1
Deb, D.K.2
Abdul, A.3
Riaz, H.4
James, L.R.5
Salameh, J.6
Nahman, N.S.7
-
12
-
-
84905980583
-
Effects of high glucose on integrin activity and fibronectin matrix assembly by mesangial cells
-
Miller, C.G.; Pozzi, A.; Zent, R.; Schwarzbauer, J.E. Effects of high glucose on integrin activity and fibronectin matrix assembly by mesangial cells. Mol. Biol. Cell, 2014, 25(16), 2342-2350.
-
(2014)
Mol. Biol. Cell
, vol.25
, Issue.16
, pp. 2342-2350
-
-
Miller, C.G.1
Pozzi, A.2
Zent, R.3
Schwarzbauer, J.E.4
-
13
-
-
77954521557
-
Advanced glycation end-products and the kidney
-
Busch, M.; Franke, S.;Ruster, C.; Wolf, G. Advanced glycation end-products and the kidney. Eur. J. Clin. Invest., 2010, 40(8), 742- 755.
-
(2010)
Eur. J. Clin. Invest.
, vol.40
, Issue.8
, pp. 742-755
-
-
Busch, M.1
Franke, S.2
Ruster, C.3
Wolf, G.4
-
14
-
-
78650657305
-
Oxidative stress in diabetic nephropathy
-
Kashihara, N.; Haruna, Y.; Kondeti, V.K.; Kanwar, Y.S. Oxidative stress in diabetic nephropathy. Curr. Med. Chem., 2010, 17(34), 4256-4269.
-
(2010)
Curr. Med. Chem.
, vol.17
, Issue.34
, pp. 4256-4269
-
-
Kashihara, N.1
Haruna, Y.2
Kondeti, V.K.3
Kanwar, Y.S.4
-
15
-
-
63449086757
-
Matrix metalloproteinases: Their potential role in the pathogenesis of diabetic nephropathy
-
Thrailkill, K.M.; Clay Bunn, R.; Fowlkes, J.L. Matrix metalloproteinases: Their potential role in the pathogenesis of diabetic nephropathy. Endocrine, 2009, 35(1), 1-10.
-
(2009)
Endocrine
, vol.35
, Issue.1
, pp. 1-10
-
-
Thrailkill, K.M.1
Clay Bunn, R.2
Fowlkes, J.L.3
-
16
-
-
84906910187
-
A glimpse of matrix metalloproteinases in diabetic nephropathy
-
Xu, X.; Xiao, L.; Xiao, P.; Yang, S.; Chen, G.; Liu, F.; Kanwar, Y.S.; Sun, L. A glimpse of matrix metalloproteinases in diabetic nephropathy. Curr. Med. Chem., 2014, 21(28), 3244-3260.
-
(2014)
Curr. Med. Chem.
, vol.21
, Issue.28
, pp. 3244-3260
-
-
Xu, X.1
Xiao, L.2
Xiao, P.3
Yang, S.4
Chen, G.5
Liu, F.6
Kanwar, Y.S.7
Sun, L.8
-
17
-
-
84906939393
-
Diabetic nephropathy-emerging epigenetic mechanisms
-
Kato, M.; Natarajan, R. Diabetic nephropathy-emerging epigenetic mechanisms. Nat. Rev. Nephrol., 2014, 10(9), 517-530.
-
(2014)
Nat. Rev. Nephrol.
, vol.10
, Issue.9
, pp. 517-530
-
-
Kato, M.1
Natarajan, R.2
-
18
-
-
70349578964
-
Role of growth factors in diabetic kidney disease
-
Chiarelli, F.; Gaspari, S.; Marcovecchio, M.L. Role of growth factors in diabetic kidney disease. Horm. Metab. Res., 2009, 41(8), 585-593.
-
(2009)
Horm. Metab. Res.
, vol.41
, Issue.8
, pp. 585-593
-
-
Chiarelli, F.1
Gaspari, S.2
Marcovecchio, M.L.3
-
19
-
-
46149123433
-
Angiotensin II- And glucose-stimulated extracellular matrix production: Mediation by the insulin-like growth factor (IGF) axis in a murine mesangial cell line
-
Davis, L.K.; Rodgers, B.D.; Kelley, K.M. Angiotensin II- And glucose-stimulated extracellular matrix production: mediation by the insulin-like growth factor (IGF) axis in a murine mesangial cell line. Endocrine, 2008, 33(1), 32-39.
-
(2008)
Endocrine
, vol.33
, Issue.1
, pp. 32-39
-
-
Davis, L.K.1
Rodgers, B.D.2
Kelley, K.M.3
-
20
-
-
64249172203
-
The canonical Notch signaling pathway: Unfolding the activation mechanism
-
Kopan, R.; Ilagan, M.X. The canonical Notch signaling pathway: unfolding the activation mechanism. Cell, 2009, 137(2), 216-233.
-
(2009)
Cell
, vol.137
, Issue.2
, pp. 216-233
-
-
Kopan, R.1
Ilagan, M.X.2
-
21
-
-
0036014932
-
Transforming growth factor-beta induces renal epithelial jagged-1 expression in fibrotic disease
-
Morrissey, J.; Guo, G.; Moridaira, K.; Fitzgerald, M.; McCracken, R.; Tolley, T.; Klahr, S. Transforming growth factor-beta induces renal epithelial jagged-1 expression in fibrotic disease. J. Am. Soc. Nephrol., 2002, 13(6), 1499-1508.
-
(2002)
J. Am. Soc. Nephrol.
, vol.13
, Issue.6
, pp. 1499-1508
-
-
Morrissey, J.1
Guo, G.2
Moridaira, K.3
Fitzgerald, M.4
McCracken, R.5
Tolley, T.6
Klahr, S.7
-
22
-
-
84879080578
-
Molecular targets for treatment of kidney fibrosis
-
Berl
-
Chuang, P.Y.; Menon, M.C.; He, J.C. Molecular targets for treatment of kidney fibrosis. J. Mol. Med. (Berl)., 2013, 91(5), 549- 559.
-
(2013)
J. Mol. Med.
, vol.91
, Issue.5
, pp. 549-559
-
-
Chuang, P.Y.1
Menon, M.C.2
He, J.C.3
-
23
-
-
79851514523
-
The story of Notch and chronic kidney disease
-
Sharma, S.; Sirin, Y.; Susztak, K. The story of Notch and chronic kidney disease. Curr. Opin. Nephrol. Hypertens., 2011, 20(1), 56- 61.
-
(2011)
Curr. Opin. Nephrol. Hypertens.
, vol.20
, Issue.1
, pp. 56-61
-
-
Sharma, S.1
Sirin, Y.2
Susztak, K.3
-
24
-
-
40449123492
-
Notch inhibition reverses kidney failure
-
Kretzler, M.; Allred, L. Notch inhibition reverses kidney failure. Nat. Med., 2008, 14(3), 246-247.
-
(2008)
Nat. Med.
, vol.14
, Issue.3
, pp. 246-247
-
-
Kretzler, M.1
Allred, L.2
-
25
-
-
79952695743
-
Targeting the jagged/notch pathway: A new treatment for fibrosis?
-
Leask, A. Targeting the jagged/notch pathway: A new treatment for fibrosis? J. Cell. Commun. Signal., 2010, 4(4), 197-198.
-
(2010)
J. Cell. Commun. Signal.
, vol.4
, Issue.4
, pp. 197-198
-
-
Leask, A.1
-
26
-
-
82755160861
-
Notch in the kidney: Development and disease
-
Sirin, Y.; Susztak, K. Notch in the kidney: development and disease. J. Pathol., 2012, 226(2), 394-403.
-
(2012)
J. Pathol.
, vol.226
, Issue.2
, pp. 394-403
-
-
Sirin, Y.1
Susztak, K.2
-
27
-
-
1842524153
-
Integration of TGF-beta/Smad and Jagged1/Notch signalling in epithelialto- mesenchymal transition
-
Zavadil, J.; Cermak, L.; Soto-Nieves, N.; Bottinger, E.P. Integration of TGF-beta/Smad and Jagged1/Notch signalling in epithelialto- mesenchymal transition. EMBO. J., 2004, 23(5), 1155-1165.
-
(2004)
EMBO. J.
, vol.23
, Issue.5
, pp. 1155-1165
-
-
Zavadil, J.1
Cermak, L.2
Soto-Nieves, N.3
Bottinger, E.P.4
-
28
-
-
78049449123
-
Epithelial Notch signaling regulates interstitial fibrosis development in the kidneys of mice and humans
-
Bielesz, B.; Sirin, Y.; Si, H.; Niranjan, T.; Gruenwald, A.; Ahn, S.; Kato, H.; Pullman, J.; Gessler, M.; Haase, V.H.;Susztak K. Epithelial Notch signaling regulates interstitial fibrosis development in the kidneys of mice and humans. J. Clin. Invest., 2010, 120(11), 4040-4054.
-
(2010)
J. Clin. Invest.
, vol.120
, Issue.11
, pp. 4040-4054
-
-
Susztak, K.1
Bielesz, B.2
Sirin, Y.3
Si, H.4
Niranjan, T.5
Gruenwald, A.6
Ahn, S.7
Kato, H.8
Pullman, J.9
Gessler, M.10
Haase, V.H.11
-
29
-
-
77955654604
-
Expression of Notch pathway proteins correlates with albuminuria, glomerulosclerosis, and renal function
-
Murea, M.; Park, J.K.; Sharma, S.; Kato, H.; Gruenwald, A.; Niranjan, T., Si, H.; Thomas, D.B.; Pullman, J.M.; Melamed, M.L.; Susztak, K. Expression of Notch pathway proteins correlates with albuminuria, glomerulosclerosis, and renal function. Kidney Int., 2010, 78(5), 514-522.
-
(2010)
Kidney Int
, vol.78
, Issue.5
, pp. 514-522
-
-
Murea, M.1
Park, J.K.2
Sharma, S.3
Kato, H.4
Gruenwald, A.5
Niranjan, T.6
Si, H.7
Thomas, D.B.8
Pullman, J.M.9
Melamed, M.L.10
Susztak, K.11
-
30
-
-
39149086711
-
Co-regulation of Gremlin and Notch signalling in diabetic nephropathy
-
Walsh, D.W.; Roxburgh, S.A.; McGettigan, P.; Berthier, C.C.; Higgins, D.G.; Kretzler, M.; Cohen, C.D.; Mezzano, S.; Brazil, D.P.; Martin, F. Co-regulation of Gremlin and Notch signalling in diabetic nephropathy. Biochim. Biophys. Acta., 2008, 1782(1), 10- 21.
-
(2008)
Biochim. Biophys. Acta.
, vol.1782
, Issue.1
, pp. 10-21
-
-
Walsh, D.W.1
Roxburgh, S.A.2
McGettigan, P.3
Berthier, C.C.4
Higgins, D.G.5
Kretzler, M.6
Cohen, C.D.7
Mezzano, S.8
Brazil, D.P.9
Martin, F.10
-
31
-
-
70350545853
-
TGF-β-Induced epithelial-to- mesenchymal transition and therapeutic intervention in diabetic nephropathy
-
Hills, C.E.; Squires, P.E. TGF-β-Induced Epithelial-to- Mesenchymal Transition and Therapeutic intervention in Diabetic Nephropathy. Am. J. Nephrol., 2010, 31, 68-74.
-
(2010)
Am. J. Nephrol.
, vol.31
, pp. 68-74
-
-
Hills, C.E.1
Squires, P.E.2
-
32
-
-
84888643463
-
Transforming growth factor-beta and the progression of renal disease
-
Loeffler, I.; Wolf, G. Transforming growth factor-beta and the progression of renal disease. Nephrol. Dial. Transplant, 2014, 29(Suppl 1), i37-i45.
-
(2014)
Nephrol. Dial. Transplant
, vol.29
, pp. i37-i45
-
-
Loeffler, I.1
Wolf, G.2
-
33
-
-
0033867789
-
Mechanism of transforming growth factor-beta1 signaling: Role of the mitogen-activated protein kinase
-
Choi, M.E. Mechanism of transforming growth factor-beta1 signaling: Role of the mitogen-activated protein kinase. Kidney Int. Suppl., 2000, 77, S53-58.
-
(2000)
Kidney Int. Suppl.
, vol.77
, pp. S53-S58
-
-
Choi, M.E.1
-
34
-
-
84859815045
-
Notch signaling in diabetic nephropathy
-
Bonegio, R.; Susztak, K. Notch signaling in diabetic nephropathy. Exp. Cell Res., 2012, 318(9), 986-992.
-
(2012)
Exp. Cell Res.
, vol.318
, Issue.9
, pp. 986-992
-
-
Bonegio, R.1
Susztak, K.2
-
35
-
-
84879329090
-
Notch signaling molecules activate TGF- beta in rat mesangial cells under high glucose conditions
-
Liu, L.; Gao, C.; Chen, G.; Li, X.; Li, J.; Wan, Q.; Xu, Y. Notch signaling molecules activate TGF- beta in rat mesangial cells under high glucose conditions. J. Diabetes Res., 2013, 2013, 979702.
-
(2013)
J. Diabetes Res.
, vol.2013
, pp. 979702
-
-
Liu, L.1
Gao, C.2
Chen, G.3
Li, X.4
Li, J.5
Wan, Q.6
Xu, Y.7
-
36
-
-
77955395425
-
Getting a notch closer to understanding diabetic kidney disease
-
Ahn, SH.; Susztak, K. Getting a notch closer to understanding diabetic kidney disease. Diabetes, 2010, 59(8), 1865-1867.
-
(2010)
Diabetes
, vol.59
, Issue.8
, pp. 1865-1867
-
-
Ahn, S.H.1
Susztak, K.2
-
37
-
-
40449112321
-
The Notch pathway in podocytes plays a role in the development of glomerular disease
-
Niranjan, T.; Bielesz, B.; Gruenwald, A.; Ponda, M.P.; Kopp, J.B.; Thomas, D.B.; Susztak, K. The Notch pathway in podocytes plays a role in the development of glomerular disease. Nat. Med., 2008, 14(3), 290-298.
-
(2008)
Nat. Med.
, vol.14
, Issue.3
, pp. 290-298
-
-
Niranjan, T.1
Bielesz, B.2
Gruenwald, A.3
Ponda, M.P.4
Kopp, J.B.5
Thomas, D.B.6
Susztak, K.7
-
38
-
-
77955366446
-
Modulation of notch-1 signaling alleviates vascular endothelial growth factor - mediated diabetic nephropathy
-
Lin, C.L.; Wang, F.S.; Hsu, Y.C.; Chen, C.N.; Tseng, M.J.; Saleem, M.A.; Chang, P.J.; Wang, J.Y. Modulation of notch-1 signaling alleviates vascular endothelial growth factor - mediated diabetic nephropathy. Diabetes, 2010, 59(8), 1915-1925.
-
(2010)
Diabetes
, vol.59
, Issue.8
, pp. 1915-1925
-
-
Lin, C.L.1
Wang, F.S.2
Hsu, Y.C.3
Chen, C.N.4
Tseng, M.J.5
Saleem, M.A.6
Chang, P.J.7
Wang, J.Y.8
-
39
-
-
84861986053
-
Wnt/beta-catenin signaling and disease
-
Clevers, H.; Nusse, R. Wnt/beta-catenin signaling and disease. Cell, 2012, 149(6), 1192-1205.
-
(2012)
Cell
, vol.149
, Issue.6
, pp. 1192-1205
-
-
Clevers, H.1
Nusse, R.2
-
40
-
-
33646166827
-
The low density lipoprotein receptor-related protein 6 interacts with glycogen synthase kinase 3 and attenuates activity
-
Mi, K.; Dolan, P.J.; Johnson, G.V. The low density lipoprotein receptor-related protein 6 interacts with glycogen synthase kinase 3 and attenuates activity. J. Biol. Chem., 2006, 281(8), 4787-4794.
-
(2006)
J. Biol. Chem.
, vol.281
, Issue.8
, pp. 4787-4794
-
-
Mi, K.1
Dolan, P.J.2
Johnson, G.V.3
-
41
-
-
84920949774
-
Wnt signaling in kidney tubulointerstitium during disease
-
Maarouf, O.H.; Ikeda, Y.; Humphreys, B.D. Wnt signaling in kidney tubulointerstitium during disease. Histol. Histopathol., 2015, 30(2), 163-71.
-
(2015)
Histol. Histopathol.
, vol.30
, Issue.2
, pp. 163-171
-
-
Maarouf, O.H.1
Ikeda, Y.2
Humphreys, B.D.3
-
42
-
-
33644813850
-
Regulation of Wnt signaling by protein-protein interaction and post-translational modifications
-
Kikuchi, A.; Kishida, S.; Yamamoto, H. Regulation of Wnt signaling by protein-protein interaction and post-translational modifications. Exp. Mol. Med., 2006, 38(1), 1-10.
-
(2006)
Exp. Mol. Med.
, vol.38
, Issue.1
, pp. 1-10
-
-
Kikuchi, A.1
Kishida, S.2
Yamamoto, H.3
-
43
-
-
12544252343
-
Beta-Catenin: A pivot between cell adhesion and Wnt signalling
-
Bienz, M. beta-Catenin: A pivot between cell adhesion and Wnt signalling. Curr. Biol., 2005, 15(2), R64-67.
-
(2005)
Curr. Biol.
, vol.15
, Issue.2
, pp. R64-E67
-
-
Bienz, M.1
-
44
-
-
77249149901
-
Wnt/beta-catenin signaling: A novel target for therapeutic intervention of fibrotic kidney disease
-
Hwang, I.; Seo, E.Y.; Ha, H. Wnt/beta-catenin signaling: A novel target for therapeutic intervention of fibrotic kidney disease. Arch. Pharm. Res., 2009, 32(12), 1653-1662.
-
(2009)
Arch. Pharm. Res.
, vol.32
, Issue.12
, pp. 1653-1662
-
-
Hwang, I.1
Seo, E.Y.2
Ha, H.3
-
45
-
-
84904046471
-
Role of Wnt signaling in tissue fibrosis, lessons from skeletal muscle and kidney
-
Cisternas, P.; Vio, C.P.; Inestrosa, N.C. Role of Wnt signaling in tissue fibrosis, lessons from skeletal muscle and kidney. Curr. Mol. Med., 2014, 14(4), 510-522.
-
(2014)
Curr. Mol. Med.
, vol.14
, Issue.4
, pp. 510-522
-
-
Cisternas, P.1
Vio, C.P.2
Inestrosa, N.C.3
-
46
-
-
65249134946
-
Wnt/betacatenin signaling promotes renal interstitial fibrosis
-
He, W.; Dai, C.; Li, Y.; Zeng, G.; Monga, S.P.; Liu, Y. Wnt/betacatenin signaling promotes renal interstitial fibrosis. J. Am. Soc. Nephrol., 2009, 20(4), 765-776.
-
(2009)
J. Am. Soc. Nephrol.
, vol.20
, Issue.4
, pp. 765-776
-
-
He, W.1
Dai, C.2
Li, Y.3
Zeng, G.4
Monga, S.P.5
Liu, Y.6
-
47
-
-
78651384347
-
Blockade of Wnt/beta-catenin signaling by paricalcitol ameliorates proteinuria and kidney injury
-
He, W.; Kang, Y.S.; Dai, C.; Liu, Y. Blockade of Wnt/beta-catenin signaling by paricalcitol ameliorates proteinuria and kidney injury. J. Am. Soc. Nephrol., 2011, 22(1), 90-103.
-
(2011)
J. Am. Soc. Nephrol.
, vol.22
, Issue.1
, pp. 90-103
-
-
He, W.1
Kang, Y.S.2
Dai, C.3
Liu, Y.4
-
48
-
-
28444468088
-
Wnt-dependent β-catenin signaling is activated after unilateral ureteral obstruction, and recombinant secreted frizzled-related protein 4 alters the progression of renal fibrosis
-
Surendran, K.; Schiavi, S.; Hruska, K. A. Wnt-dependent β-catenin signaling is activated after unilateral ureteral obstruction, and recombinant secreted frizzled-related protein 4 alters the progression of renal fibrosis. J. Am. Soc. Nephrol., 2005, 16, 2373- 2384.
-
(2005)
J. Am. Soc. Nephrol.
, vol.16
, pp. 2373-2384
-
-
Surendran, K.1
Schiavi, S.2
Hruska, K.A.3
-
49
-
-
84859179083
-
Activation of canonical Wnt signalling is required for TGF-beta-mediated fibrosis
-
Akhmetshina, A.; Palumbo, K.; Dees, C.; Bergmann, C.; Venalis, P.; Zerr, P.; Horn, A.; Kireva, T.; Beyer, C.; Zwerina, J.;Schneider, H.; Sadowski, A.; Riener, M.O.; MacDougald, O.A.; Distler, O.; Schett, G.; Distler, J. H. Activation of canonical Wnt signalling is required for TGF-beta-mediated fibrosis. Nat. Commun., 2012, 3, 735.
-
(2012)
Nat. Commun.
, vol.3
, pp. 735
-
-
Akhmetshina, A.1
Palumbo, K.2
Dees, C.3
Bergmann, C.4
Venalis, P.5
Zerr, P.6
Horn, A.7
Kireva, T.8
Beyer, C.9
Zwerina, J.10
Schneider, H.11
Sadowski, A.12
Riener, M.O.13
MacDougald, O.A.14
Distler, O.15
Schett, G.16
Distler, J.H.17
-
50
-
-
84871564249
-
Sustained Wnt/beta-catenin signaling rescues high glucose induction of transforming growth factor-beta1-mediated renal fibrosis
-
Ho, C.; Lee, P.H.; Hsu, Y.C.; Wang, F.S.; Huang, Y.T.; Lin, C.L. Sustained Wnt/beta-catenin signaling rescues high glucose induction of transforming growth factor-beta1-mediated renal fibrosis. Am. J. Med. Sci., 2012, 344(5), 374-382.
-
(2012)
Am. J. Med. Sci.
, vol.344
, Issue.5
, pp. 374-382
-
-
Ho, C.1
Lee, P.H.2
Hsu, Y.C.3
Wang, F.S.4
Huang, Y.T.5
Lin, C.L.6
-
51
-
-
84896126899
-
A glimpse of the pathogenetic mechanisms of Wnt/beta-catenin signaling in diabetic nephropathy
-
Xiao, L.; Wang, M.; Yang, S.; Liu, F.; Sun, L. A glimpse of the pathogenetic mechanisms of Wnt/beta-catenin signaling in diabetic nephropathy. Biomed. Res. Int., 2013, 2013, 987064.
-
(2013)
Biomed. Res. Int.
, vol.2013
, pp. 987064
-
-
Xiao, L.1
Wang, M.2
Yang, S.3
Liu, F.4
Sun, L.5
-
52
-
-
33749251120
-
Wnt/beta-catenin signaling modulates survival of high glucose-stressed mesangial cells
-
Lin, C.L.; Wang, J.Y.; Huang, Y.T.; Kuo, Y.H.; Surendran, K.; Wang, F.S. Wnt/beta-catenin signaling modulates survival of high glucose-stressed mesangial cells. J. Am. Soc. Nephrol., 2006, 17(10), 2812-2820.
-
(2006)
J. Am. Soc. Nephrol.
, vol.17
, Issue.10
, pp. 2812-2820
-
-
Lin, C.L.1
Wang, J.Y.2
Huang, Y.T.3
Kuo, Y.H.4
Surendran, K.5
Wang, F.S.6
-
53
-
-
45849144386
-
Wnt signaling in kidney development and disease
-
Pulkkinen, K.; Murugan, S.; Vainio, S. Wnt signaling in kidney development and disease. Organogenesis, 2008, 4(2), 55-59.
-
(2008)
Organogenesis
, vol.4
, Issue.2
, pp. 55-59
-
-
Pulkkinen, K.1
Murugan, S.2
Vainio, S.3
-
54
-
-
44249108994
-
Superoxide destabilization of beta-catenin augments apoptosis of high-glucose-stressed mesangial cells
-
Lin, C.L.; Wang, J.Y.; Ko, J.Y.; Surendran, K.; Huang, Y.T.; Kuo, Y.H.; Wang, F.S. Superoxide destabilization of beta-catenin augments apoptosis of high-glucose-stressed mesangial cells. Endocrinology, 2008, 149(6), 2934-2942.
-
(2008)
Endocrinology
, vol.149
, Issue.6
, pp. 2934-2942
-
-
Lin, C.L.1
Wang, J.Y.2
Ko, J.Y.3
Surendran, K.4
Huang, Y.T.5
Kuo, Y.H.6
Wang, F.S.7
-
55
-
-
10944263493
-
High glucose evokes an intrinsic proapoptotic signaling pathway in mesangial cells
-
Mishra, R.; Emancipator, S.N.; Kern, T.; Simonson, M.S. High glucose evokes an intrinsic proapoptotic signaling pathway in mesangial cells. Kidney Int., 2005, 67(1), 82-93.
-
(2005)
Kidney Int
, vol.67
, Issue.1
, pp. 82-93
-
-
Mishra, R.1
Emancipator, S.N.2
Kern, T.3
Simonson, M.S.4
-
56
-
-
38349045501
-
Simvastatin reverses high glucose-induced apoptosis of mesangial cells via modulation of Wnt signaling pathway
-
Lin, C.L.; Cheng, H.; Tung, C.W.; Huang, W.J.; Chang, P.J.; Yang, J.T.; Wang, J.Y. Simvastatin reverses high glucose-induced apoptosis of mesangial cells via modulation of Wnt signaling pathway. Am. J. Nephrol., 2008, 28(2), 290-297.
-
(2008)
Am. J. Nephrol.
, vol.28
, Issue.2
, pp. 290-297
-
-
Lin, C.L.1
Cheng, H.2
Tung, C.W.3
Huang, W.J.4
Chang, P.J.5
Yang, J.T.6
Wang, J.Y.7
-
57
-
-
75149137022
-
Dickkopf-1 promotes hyperglycemia-induced accumulation of mesangial matrix and renal dysfunction
-
Lin, C.L.; Wang, J.Y.; Ko, J.Y.; Huang, Y.T.; Kuo, Y.H.; Wang, F.S. Dickkopf-1 promotes hyperglycemia-induced accumulation of mesangial matrix and renal dysfunction. J. Am. Soc. Nephrol., 2010, 21(1), 124-135.
-
(2010)
J. Am. Soc. Nephrol.
, vol.21
, Issue.1
, pp. 124-135
-
-
Lin, C.L.1
Wang, J.Y.2
Ko, J.Y.3
Huang, Y.T.4
Kuo, Y.H.5
Wang, F.S.6
-
58
-
-
84874830679
-
Functional implications of microRNA-215 in TGF-beta1-induced phenotypic transition of mesangial cells by targeting CTNNBIP1
-
Mu, J.; Pang, Q.; Guo, Y.H.; Chen, J.G.; Zeng, W.; Huang, Y.J.; Zhang, J.; Feng, B. Functional implications of microRNA-215 in TGF-beta1-induced phenotypic transition of mesangial cells by targeting CTNNBIP1. PLoS One, 2013, 8(3), e58622.
-
(2013)
PLoS One
, vol.8
, Issue.3
, pp. e58622
-
-
Mu, J.1
Pang, Q.2
Guo, Y.H.3
Chen, J.G.4
Zeng, W.5
Huang, Y.J.6
Zhang, J.7
Feng, B.8
-
59
-
-
84863049577
-
Implication of dysregulation of the canonical wingless-type MMTV integration site (WNT) pathway in diabetic nephropathy
-
Zhou, T.; He, X.; Cheng, R.; Zhang, B.; Zhang, R.R.; Chen, Y.; Takahashi, Y.; Murray, A.R.; Lee, K.; Gao, G.; Ma, J.X. Implication of dysregulation of the canonical wingless-type MMTV integration site (WNT) pathway in diabetic nephropathy. Diabetologia, 2012, 55(1), 255-266.
-
(2012)
Diabetologia
, vol.55
, Issue.1
, pp. 255-266
-
-
Zhou, T.1
He, X.2
Cheng, R.3
Zhang, B.4
Zhang, R.R.5
Chen, Y.6
Takahashi, Y.7
Murray, A.R.8
Lee, K.9
Gao, G.10
Ma, J.X.11
-
60
-
-
79551483244
-
CTGF/CCN2 activates canonical Wnt signalling in mesangial cells through LRP6: Implications for the pathogenesis of diabetic nephropathy
-
Rooney, B.; O'Donovan, H.; Gaffney, A.; Browne, M.; Faherty, N.; Curran, S.P.; Sadlier, D.; Godson, C.; Brazil, D.P.; Crean, J. CTGF/CCN2 activates canonical Wnt signalling in mesangial cells through LRP6: implications for the pathogenesis of diabetic nephropathy. FEBS. Lett., 2011, 585(3), 531-538.
-
(2011)
FEBS. Lett.
, vol.585
, Issue.3
, pp. 531-538
-
-
Rooney, B.1
O'Donovan, H.2
Gaffney, A.3
Browne, M.4
Faherty, N.5
Curran, S.P.6
Sadlier, D.7
Godson, C.8
Brazil, D.P.9
Crean, J.10
-
61
-
-
84871093351
-
Wnt signalling in kidney diseases: Dual roles in renal injury and repair
-
Kawakami, T.; Ren, S.; Duffield, J.S. Wnt signalling in kidney diseases: dual roles in renal injury and repair. J. Pathol., 2013, 229(2), 221-231.
-
(2013)
J. Pathol.
, vol.229
, Issue.2
, pp. 221-231
-
-
Kawakami, T.1
Ren, S.2
Duffield, J.S.3
-
62
-
-
77949351029
-
New insights into epithelial-mesenchymal transition in kidney fibrosis
-
Liu, Y. New insights into epithelial-mesenchymal transition in kidney fibrosis. J. Am. Soc. Nephrol., 2010, 21(2), 212-222.
-
(2010)
J. Am. Soc. Nephrol.
, vol.21
, Issue.2
, pp. 212-222
-
-
Liu, Y.1
-
63
-
-
77951528072
-
Troglitazone ameliorates high glucose-induced EMT and dysfunction of SGLTs through PI3K/Akt, GSK-3beta, Snail1, and beta-catenin in renal proximal tubule cells
-
Lee, Y.J.; Han, H.J. Troglitazone ameliorates high glucose-induced EMT and dysfunction of SGLTs through PI3K/Akt, GSK-3beta, Snail1, and beta-catenin in renal proximal tubule cells. Am. J. Physiol. Renal. Physiol., 2010, 298(5), F1263-1275.
-
(2010)
Am. J. Physiol. Renal. Physiol.
, vol.298
, Issue.5
, pp. F1263-F1275
-
-
Lee, Y.J.1
Han, H.J.2
-
64
-
-
84919435928
-
Connective tissue growth factor induces tubular epithelial to mesenchymal transition through the activation of canonical Wnt signaling in vitro
-
Yang, Z.; Sun, L.; Nie, H.; Liu, H.; Liu, G.; Guan, G. Connective tissue growth factor induces tubular epithelial to mesenchymal transition through the activation of canonical Wnt signaling in vitro. Ren. Fail., 2015, 37(1), 129-135.
-
(2015)
Ren. Fail.
, vol.37
, Issue.1
, pp. 129-135
-
-
Yang, Z.1
Sun, L.2
Nie, H.3
Liu, H.4
Liu, G.5
Guan, G.6
-
65
-
-
69849089270
-
Wnt/β-catenin signaling promotes podocyte dysfunction and abuminuria
-
Dai, C.; Stolz, D.B.; Kiss, L.P.; Monga, S.P.; Holzman, L.B.; Liu, Y. Wnt/β-catenin signaling promotes podocyte dysfunction and abuminuria. J. Am. Soc. Nephrol., 2009, 20(9), 1997-2008.
-
(2009)
J. Am. Soc. Nephrol.
, vol.20
, Issue.9
, pp. 1997-2008
-
-
Dai, C.1
Stolz, D.B.2
Kiss, L.P.3
Monga, S.P.4
Holzman, L.B.5
Liu, Y.6
-
66
-
-
79960425136
-
Wnt/β-Catenin pathway in podocytes integrates cell adhesion, differentiation, and survival
-
Kato, H.; Gruenwald, A.; Suh, J.H.; Miner, J.H.; Barisoni-Thomas, L.; Taketo, M.M.; Faul, C.; Millar, S.E.; Holzman, L.B.; Susztak, K. Wnt/β-Catenin Pathway in Podocytes Integrates Cell Adhesion, Differentiation, and Survival. J. Biol. Chem., 2011, 286(29), 26003-26015.
-
(2011)
J. Biol. Chem.
, vol.286
, Issue.29
, pp. 26003-26015
-
-
Kato, H.1
Gruenwald, A.2
Suh, J.H.3
Miner, J.H.4
Barisoni-Thomas, L.5
Taketo, M.M.6
Faul, C.7
Millar, S.E.8
Holzman, L.B.9
Susztak, K.10
-
67
-
-
84872004572
-
Wnt/β-catenin signalling pathway mediates high glucose induced cell injury through activation of TRPC6 in podocytes
-
Li, Z.; Xu, J.; Xu, P.; Liu, S.; Yang, Z. Wnt/β-catenin signalling pathway mediates high glucose induced cell injury through activation of TRPC6 in podocytes. Cell Prolif., 2013, 46(1), 76-85.
-
(2013)
Cell Prolif
, vol.46
, Issue.1
, pp. 76-85
-
-
Li, Z.1
Xu, J.2
Xu, P.3
Liu, S.4
Yang, Z.5
-
68
-
-
84859778293
-
MTOR signaling in growth control and disease
-
Laplante, M.; Sabatini, D.M. mTOR signaling in growth control and disease. Cell, 2012, 149(2), 274-293.
-
(2012)
Cell
, vol.149
, Issue.2
, pp. 274-293
-
-
Laplante, M.1
Sabatini, D.M.2
-
69
-
-
63749105226
-
MTOR and the control of whole body metabolism
-
Polak, P.; Hall, M.N. mTOR and the control of whole body metabolism. Curr. Opin. Cell Biol., 2009, 21(2), 209-218.
-
(2009)
Curr. Opin. Cell Biol.
, vol.21
, Issue.2
, pp. 209-218
-
-
Polak, P.1
Hall, M.N.2
-
70
-
-
77949831941
-
Abnormalities in signaling pathways in diabetic nephropathy
-
Brosius, F.C.; Khoury, C.C.; Buller, C.L.; Chen, S. Abnormalities in signaling pathways in diabetic nephropathy. Expert. Rev. Endocrinol. Metab., 2010, 5(1), 51-64.
-
(2010)
Expert. Rev. Endocrinol. Metab.
, vol.5
, Issue.1
, pp. 51-64
-
-
Brosius, F.C.1
Khoury, C.C.2
Buller, C.L.3
Chen, S.4
-
71
-
-
33845265927
-
mRNA translation: Unexplored territory in renal science
-
Kasinath, B.S.; Mariappan, M.M.; Sataranatarajan, K.; Lee, M.J.; Feliers, D. mRNA translation: unexplored territory in renal science. J. Am. Soc. Nephrol., 2006, 17(12), 3281-3292.
-
(2006)
J. Am. Soc. Nephrol.
, vol.17
, Issue.12
, pp. 3281-3292
-
-
Kasinath, B.S.1
Mariappan, M.M.2
Sataranatarajan, K.3
Lee, M.J.4
Feliers, D.5
-
72
-
-
33847024296
-
High glucose, high insulin, and their combination rapidly induce laminin-beta1 synthesis by regulation of mRNA translation in renal epithelial cells
-
Mariappan, M.M.; Feliers, D.; Mummidi, S.; Choudhury, G.G.; Kasinath, B.S. High glucose, high insulin, and their combination rapidly induce laminin-beta1 synthesis by regulation of mRNA translation in renal epithelial cells. Diabetes, 2007, 56(2), 476-485.
-
(2007)
Diabetes
, vol.56
, Issue.2
, pp. 476-485
-
-
Mariappan, M.M.1
Feliers, D.2
Mummidi, S.3
Choudhury, G.G.4
Kasinath, B.S.5
-
73
-
-
72049105867
-
The role of the mammalian target of rapamycin (mTOR) in renal disease
-
Lieberthal, W.; Levine, J.S. The role of the mammalian target of rapamycin (mTOR) in renal disease. J. Am. Soc. Nephrol., 2009, 20(12), 2493-2502.
-
(2009)
J. Am. Soc. Nephrol.
, vol.20
, Issue.12
, pp. 2493-2502
-
-
Lieberthal, W.1
Levine, J.S.2
-
74
-
-
33646352217
-
Mammalian target of rapamycin pathway blockade slows progression of diabetic kidney disease
-
Lioberas, N.; Cruzado, J.M.; Franquesa, M.; Herrero-Fresneda, I.; Torras, J.; Alperovich, G.; Rama, I.; Vidal, A.; Grinyo, J.M. Mammalian target of rapamycin pathway blockade slows progression of diabetic kidney disease. J. Am. Soc. Nephrol., 2006, 17(5), 1395-1404.
-
(2006)
J. Am. Soc. Nephrol.
, vol.17
, Issue.5
, pp. 1395-1404
-
-
Lioberas, N.1
Cruzado, J.M.2
Franquesa, M.3
Herrero-Fresneda, I.4
Torras, J.5
Alperovich, G.6
Rama, I.7
Vidal, A.8
Grinyo, J.M.9
-
75
-
-
65649120747
-
The mTOR pathway is highly activated in diabetic nephropathy and rapamycin has a strong therapeutic potential
-
Mori, H.; Inoki, K.; Masutani, K.; Wakabayashi, Y.; Komai, K.; Nakagawa, R.;Guan, K.L.; Yoshimura, A. The mTOR pathway is highly activated in diabetic nephropathy and rapamycin has a strong therapeutic potential. Biochem. Biophys. Res. Commun., 2009, 384(4), 471-475.
-
(2009)
Biochem. Biophys. Res. Commun.
, vol.384
, Issue.4
, pp. 471-475
-
-
Mori, H.1
Inoki, K.2
Masutani, K.3
Wakabayashi, Y.4
Komai, K.5
Nakagawa, R.6
Guan, K.L.7
Yoshimura, A.8
-
76
-
-
29244486472
-
Inhibition of mTOR signaling with rapamycin attenuates renal hypertrophy in the early diabetic mice
-
Sakaguchi, M.; Isono, M.; Isshiki, K.; Sugimoto, T.; Koya, D.; Kashiwagi, A. Inhibition of mTOR signaling with rapamycin attenuates renal hypertrophy in the early diabetic mice. Biochem. Biophys. Res. Commun., 2006, 340(1), 296-301.
-
(2006)
Biochem. Biophys. Res. Commun.
, vol.340
, Issue.1
, pp. 296-301
-
-
Sakaguchi, M.1
Isono, M.2
Isshiki, K.3
Sugimoto, T.4
Koya, D.5
Kashiwagi, A.6
-
77
-
-
34748880045
-
Rapamycin prevents early steps of the development of diabetic nephropathy in rats
-
Yang, Y.; Wang, J.; Qin, L.; Shou, Z.; Zhao, J.; Wang, H.; Chen, Y.; Chen, J. Rapamycin prevents early steps of the development of diabetic nephropathy in rats. Am. J. Nephrol., 2007, 27(5), 495- 502.
-
(2007)
Am. J. Nephrol.
, vol.27
, Issue.5
, pp. 495-502
-
-
Yang, Y.1
Wang, J.2
Qin, L.3
Shou, Z.4
Zhao, J.5
Wang, H.6
Chen, Y.7
Chen, J.8
-
78
-
-
84893842033
-
MTOR controls kidney epithelia in health and disease
-
Grahammer, F.; Wanner, N.; Huber, T.B. mTOR controls kidney epithelia in health and disease. Nephrol. Dial. Transplant, 2014, 29 Suppl 1, i9-i18.
-
(2014)
Nephrol. Dial. Transplant
, vol.29
, pp. i9-i18
-
-
Grahammer, F.1
Wanner, N.2
Huber, T.B.3
-
79
-
-
38349057990
-
Regulation of elongation phase of mRNA translation in diabetic nephropathy: Amelioration by rapamycin
-
Sataranatarajan, K.; Mariappan, M.M.; Lee, M.J.; Feliers, D.; Choudhury, G.G.; Barnes, J.L.; Kasinath, B.S. Regulation of elongation phase of mRNA translation in diabetic nephropathy: Amelioration by rapamycin. Am. J. Pathol., 2007, 171(6), 1733-1742.
-
(2007)
Am. J. Pathol.
, vol.171
, Issue.6
, pp. 1733-1742
-
-
Sataranatarajan, K.1
Mariappan, M.M.2
Lee, M.J.3
Feliers, D.4
Choudhury, G.G.5
Barnes, J.L.6
Kasinath, B.S.7
-
80
-
-
84879481399
-
Losartan affects glomerular AKT and mTOR phosphorylation in an experimental model of type 1 diabetic nephropathy
-
Mavroeidi, V.; Petrakis, I.; Stylianou, K.; Katsarou, T.; Giannakakis, K.; Perakis, K.; Vardaki, E.; Stratigis, S.; Ganotakis, E.; Papavasiliou, S., Daphnis, E. Losartan affects glomerular AKT and mTOR phosphorylation in an experimental model of type 1 diabetic nephropathy. J. Histochem. Cytochem., 2013, 61(6), 433-443.
-
(2013)
J. Histochem. Cytochem.
, vol.61
, Issue.6
, pp. 433-443
-
-
Mavroeidi, V.1
Petrakis, I.2
Stylianou, K.3
Katsarou, T.4
Giannakakis, K.5
Perakis, K.6
Vardaki, E.7
Stratigis, S.8
Ganotakis, E.9
Papavasiliou, S.10
Daphnis, E.11
-
81
-
-
77954957730
-
The combination of sirolimus and rosiglitazone produces a renoprotective effect on diabetic kidney disease in rats
-
Flaquer, M.; Lloberas, N.; Franquesa, M.; Torras, J.; Vidal, A.; Rosa, J.L.; Herrero-Fresneda, I.; Grinyo, J.M.; Cruzado, J.M. The combination of sirolimus and rosiglitazone produces a renoprotective effect on diabetic kidney disease in rats. Life Sci., 2010, 87(5- 6), 147-153.
-
(2010)
Life Sci
, vol.87
, Issue.5-6
, pp. 147-153
-
-
Flaquer, M.1
Lloberas, N.2
Franquesa, M.3
Torras, J.4
Vidal, A.5
Rosa, J.L.6
Herrero-Fresneda, I.7
Grinyo, J.M.8
Cruzado, J.M.9
-
82
-
-
84884652645
-
Alterations in tubular epithelial cells in diabetic nephropathy
-
Habib, S.L. Alterations in tubular epithelial cells in diabetic nephropathy. J. Nephrol., 2013, 26(5), 865-869.
-
(2013)
J. Nephrol.
, vol.26
, Issue.5
, pp. 865-869
-
-
Habib, S.L.1
-
83
-
-
80055108638
-
MTOR in podocyte function Is rapamycin good for diabetic nephropathy?
-
Lu, M.K.; Gong, X.G.; Guan, K.L. mTOR in podocyte function Is rapamycin good for diabetic nephropathy? Cell Cycle, 2011, 10(20), 3415-3416.
-
(2011)
Cell Cycle
, vol.10
, Issue.20
, pp. 3415-3416
-
-
Lu, M.K.1
Gong, X.G.2
Guan, K.L.3
-
84
-
-
79957881425
-
Role of mTOR in podocyte function and diabetic nephropathy in humans and mice
-
Gödel, M.; Hartleben, B.; Herbach, N.; Liu, S.; Zschiedrich, S.; Lu, S.; Debreczeni-Mór, A.; Lindenmeyer, M.T.; Rastaldi, M.P.; Hartleben, G.; Wiech, T.; Fornoni, A.; Nelson, R.G.; Kretzler, M.; Wanke, R.; Pavenstädt, H.; Kerjaschki, D.; Cohen, C.D.; Hall, M.N.; Ruegg, M.A.;Inoki, K.; Walz, G.; Huber, T.B. Role of mTOR in podocyte function and diabetic nephropathy in humans and mice. J. Clin. Invest., 2011, 121(6), 2197-2209.
-
(2011)
J. Clin. Invest.
, vol.121
, Issue.6
, pp. 2197-2209
-
-
Gödel, M.1
Hartleben, B.2
Herbach, N.3
Liu, S.4
Zschiedrich, S.5
Lu, S.6
Debreczeni-Mór, A.7
Lindenmeyer, M.T.8
Rastaldi, M.P.9
Hartleben, G.10
Wiech, T.11
Fornoni, A.12
Nelson, R.G.13
Kretzler, M.14
Wanke, R.15
Pavenstädt, H.16
Kerjaschki, D.17
Cohen, C.D.18
Hall, M.N.19
Ruegg, M.A.20
Inoki, K.21
Walz, G.22
Huber, T.B.23
more..
-
85
-
-
79957927211
-
MTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice
-
Inoki, K.; Mori, H.; Wang, J.; Suzuki, T.; Hong, S.; Yoshida, S.; Blattner, S.M.; Ikenoue, T.; Ruegg, M.A.; Hall, M.N.; Kwiatkowski, D.J.; Rastaldi, M.P.; Huber, T.B.; Kretzler, M.; Holzman, L.B.; Wiggins, R.C.; Guan, K.L. mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice. J. Clin. Invest., 2011, 121(6), 2181-2196.
-
(2011)
J. Clin. Invest.
, vol.121
, Issue.6
, pp. 2181-2196
-
-
Inoki, K.1
Mori, H.2
Wang, J.3
Suzuki, T.4
Hong, S.5
Yoshida, S.6
Blattner, S.M.7
Ikenoue, T.8
Ruegg, M.A.9
Hall, M.N.10
Kwiatkowski, D.J.11
Rastaldi, M.P.12
Huber, T.B.13
Kretzler, M.14
Holzman, L.B.15
Wiggins, R.C.16
Guan, K.L.17
-
86
-
-
33845951211
-
DAMPs, PAMPs and alarmins: All we need to know about danger
-
Bianchi, M.E. DAMPs, PAMPs and alarmins: All we need to know about danger. J. Leukoc., Biol. 2007, 81(1), 1-5.
-
(2007)
J. Leukoc., Biol.
, vol.81
, Issue.1
, pp. 1-5
-
-
Bianchi, M.E.1
-
87
-
-
67649873047
-
Toll-like receptors and renal disease
-
Robson, M.G. Toll-like receptors and renal disease. Nephron Exp. Nephrol., 2009, 113(1), e1-7.
-
(2009)
Nephron Exp. Nephrol.
, vol.113
, Issue.1
, pp. e1-e7
-
-
Robson, M.G.1
-
88
-
-
84897464330
-
Toll-like receptors: Sensing and reacting to diabetic injury in the kidney
-
Lin, M.;Tang, S.C. Toll-like receptors: sensing and reacting to diabetic injury in the kidney. Nephrol. Dial. Transplant, 2014, 29(4), 746-754.
-
(2014)
Nephrol. Dial. Transplant
, vol.29
, Issue.4
, pp. 746-754
-
-
Lin, M.1
Tang, S.C.2
-
89
-
-
84893967901
-
Role of Toll-like receptors in diabetic nephropathy
-
Lond
-
Mudaliar, H.; Pollock, C.; Panchapakesan, U. Role of Toll-like receptors in diabetic nephropathy. Clin. Sci. (Lond)., 2014, 126(10), 685-694.
-
(2014)
Clin. Sci.
, vol.126
, Issue.10
, pp. 685-694
-
-
Mudaliar, H.1
Pollock, C.2
Panchapakesan, U.3
-
90
-
-
84925120711
-
Diabetic nephropathy and proximal tubular damage
-
Tang, S.C.; Yiu, W.H; Lin, M.; Lai, K.N. Diabetic nephropathy and proximal tubular damage. J. Ren. Nutr., 2015, 25(2), 230-233.
-
(2015)
J. Ren. Nutr.
, vol.25
, Issue.2
, pp. 230-233
-
-
Tang, S.C.1
Yiu, W.H.2
Lin, M.3
Lai, K.N.4
-
91
-
-
84894026294
-
Requirement for TLR2 in the development of albuminuria, inflammation and fibrosis in experimental diabetic nephropathy
-
Ma, J.; Wu, H.; Zhao, C.Y.; Panchapakesan, U.; Pollock, C.; Chadban, S.J. Requirement for TLR2 in the development of albuminuria, inflammation and fibrosis in experimental diabetic nephropathy. Int. J. Clin. Exp. Pathol., 2014, 7(2), 481-495.
-
(2014)
Int. J. Clin. Exp. Pathol.
, vol.7
, Issue.2
, pp. 481-495
-
-
Ma, J.1
Wu, H.2
Zhao, C.Y.3
Panchapakesan, U.4
Pollock, C.5
Chadban, S.J.6
-
92
-
-
84940860220
-
Podocyte apoptosis is prevented by blocking the Toll-like receptor pathway
-
Saurus, P.; Kuusela, S.; Lehtonen, E.; Hyvonen, M.E.; Ristola, M.; Fogarty, C.L.; Tienari, J.; Lassenius, M.I.; Forsblom, C.; Lehto, M.; Saleem, M.A.; Groop, P.H.; Holthofer, H.; Lehtonen, S. Podocyte apoptosis is prevented by blocking the Toll-like receptor pathway. Cell Death Dis., 2015, 6, e1752.
-
(2015)
Cell Death Dis
, vol.6
, pp. e1752
-
-
Saurus, P.1
Kuusela, S.2
Lehtonen, E.3
Hyvonen, M.E.4
Ristola, M.5
Fogarty, C.L.6
Tienari, J.7
Lassenius, M.I.8
Forsblom, C.9
Lehto, M.10
Saleem, M.A.11
Groop, P.H.12
Holthofer, H.13
Lehtonen, S.14
-
93
-
-
80051544616
-
Knockout of toll-like receptor-2 attenuates both the proinflammatory state of diabetes and incipient diabetic nephropathy
-
Devaraj, S.; Tobias, P.; Kasinath, B.S.; Ramsamooj, R.; Afify, A.; Jialal, I. Knockout of toll-like receptor-2 attenuates both the proinflammatory state of diabetes and incipient diabetic nephropathy. Arterioscler. Thromb. Vasc. Biol., 2011, 31(8), 1796-1804.
-
(2011)
Arterioscler. Thromb. Vasc. Biol.
, vol.31
, Issue.8
, pp. 1796-1804
-
-
Devaraj, S.1
Tobias, P.2
Kasinath, B.S.3
Ramsamooj, R.4
Afify, A.5
Jialal, I.6
-
94
-
-
79955586970
-
Toll-like receptor 4: A novel signaling pathway during renal fibrogenesis
-
Campbell, M.T.; Hile, K.L.; Zhang, H.; Asanuma, H.; Vanderbrink, B.A.; Rink, R.R.; Meldrum, K.K. Toll-like receptor 4: A novel signaling pathway during renal fibrogenesis. J. Surg. Res., 2011, 168(1), e61-69.
-
(2011)
J. Surg. Res.
, vol.168
, Issue.1
, pp. e61-e69
-
-
Campbell, M.T.1
Hile, K.L.2
Zhang, H.3
Asanuma, H.4
Vanderbrink, B.A.5
Rink, R.R.6
Meldrum, K.K.7
-
95
-
-
77955604860
-
TLR4 promotes fibrosis but attenuates tubular damage in progressive renal injury
-
Pulskens, W.P.; Rampanelli, E.; Teske, G.J.; Butter, L.M.; Claessen, N.; Luirink, I.K.; van der Poll, T.; Florquin, S.; and Leemans, J.C. TLR4 promotes fibrosis but attenuates tubular damage in progressive renal injury. J. Am. Soc. Nephrol., 2010, 21(8), 1299-1308.
-
(2010)
J. Am. Soc. Nephrol.
, vol.21
, Issue.8
, pp. 1299-1308
-
-
Pulskens, W.P.1
Rampanelli, E.2
Teske, G.J.3
Butter, L.M.4
Claessen, N.5
Luirink, I.K.6
Van Der Poll, T.7
Florquin, S.8
Leemans, J.C.9
-
96
-
-
84901303677
-
TLR4 activation promotes podocyte injury and interstitial fibrosis in diabetic nephropathy
-
Ma, J.; Chadban, S.J.; Zhao, C.Y.; Chen, X.; Kwan, T.; Panchapakesan, U.; Pollock, C.A.; Wu, H. TLR4 activation promotes podocyte injury and interstitial fibrosis in diabetic nephropathy. PLoS One, 2014, 9(5), e97985.
-
(2014)
PLoS One
, vol.9
, Issue.5
, pp. e97985
-
-
Ma, J.1
Chadban, S.J.2
Zhao, C.Y.3
Chen, X.4
Kwan, T.5
Panchapakesan, U.6
Pollock, C.A.7
Wu, H.8
-
97
-
-
84866381264
-
Exacerbation of diabetic nephropathy by hyperlipidaemia is mediated by Toll-like receptor 4 in mice
-
Kuwabara, T.; Mori, K.; Mukoyama, M.; Kasahara, M.; Yokoi, H., Saito, Y.; Ogawa, Y.; Imamaki, H.; Kawanishi, T.; Ishii, A.;Koga, K.; Mori, K.P.; Kato, Y.; Sugawara, A.; Nakao, K. Exacerbation of diabetic nephropathy by hyperlipidaemia is mediated by Toll-like receptor 4 in mice. Diabetologia, 2012, 55(8), 2256-2266.
-
(2012)
Diabetologia
, vol.55
, Issue.8
, pp. 2256-2266
-
-
Kuwabara, T.1
Mori, K.2
Mukoyama, M.3
Kasahara, M.4
Yokoi, H.5
Saito, Y.6
Ogawa, Y.7
Imamaki, H.8
Kawanishi, T.9
Ishii, A.10
Koga, K.11
Mori, K.P.12
Kato, Y.13
Sugawara, A.14
Nakao, K.15
-
98
-
-
84908316746
-
Global Toll-like receptor 4 knockout results in decreased renal inflammation, fibrosis and podocytopathy
-
Jialal, I.; Major, A.M.; Devaraj, S.J. Global Toll-like receptor 4 knockout results in decreased renal inflammation, fibrosis and podocytopathy. J. Diabetes Complications, 2014, 28(6), 755-761.
-
(2014)
J. Diabetes Complications
, vol.28
, Issue.6
, pp. 755-761
-
-
Jialal, I.1
Major, A.M.2
Devaraj, S.J.3
-
99
-
-
84867708435
-
Hyperglycemia induces Toll like receptor 4 expression and activity in mouse mesangial cells: Relevance to diabetic nephropathy
-
Kaur, H.; Chien, A.; and Jialal, I. Hyperglycemia induces Toll like receptor 4 expression and activity in mouse mesangial cells: Relevance to diabetic nephropathy. Am. J. Physiol. Renal Physiol., 2012, 303(8), F1145-1150.
-
(2012)
Am. J. Physiol. Renal Physiol.
, vol.303
, Issue.8
, pp. F1145-F1150
-
-
Kaur, H.1
Chien, A.2
Jialal, I.3
-
100
-
-
84862922902
-
Toll-like receptor 4 promotes tubular inflammation in diabetic nephropathy
-
Lin, M.; Yiu, W.H.; Wu, H.J.; Chan, L.Y.; Leung, J.C.; Au, W.S.; Chan, K.W.; Lai, K.N.; Tang, S.C. Toll-like receptor 4 promotes tubular inflammation in diabetic nephropathy. J. Am. Soc. Nephrol., 2012, 23(1), 86-102.
-
(2012)
J. Am. Soc. Nephrol.
, vol.23
, Issue.1
, pp. 86-102
-
-
Lin, M.1
Yiu, W.H.2
Wu, H.J.3
Chan, L.Y.4
Leung, J.C.5
Au, W.S.6
Chan, K.W.7
Lai, K.N.8
Tang, S.C.9
-
101
-
-
84878446398
-
Renal protective effects of toll-like receptor 4 signaling blockade in type 2 diabetic mice
-
Cha, J.J.; Hyun, Y.Y.; Lee, M.H.; Kim, J.E.; Nam, D.H.; Song, H.K.; Kang, Y.S.; Lee, J.E.; Kim, H.W.; Han, J.Y.; Cha, D.R. Renal protective effects of toll-like receptor 4 signaling blockade in type 2 diabetic mice. Endocrinology, 2013, 154(6), 2144-2155.
-
(2013)
Endocrinology
, vol.154
, Issue.6
, pp. 2144-2155
-
-
Cha, J.J.1
Hyun, Y.Y.2
Lee, M.H.3
Kim, J.E.4
Nam, D.H.5
Song, H.K.6
Kang, Y.S.7
Lee, J.E.8
Kim, H.W.9
Han, J.Y.10
Cha, D.R.11
-
102
-
-
0035135929
-
Small GTP-binding proteins
-
Takai, Y.; Sasaki, T.; Matozaki, T. Small GTP-binding proteins. Physiol. Rev., 2001, 81(1), 153-208.
-
(2001)
Physiol. Rev.
, vol.81
, Issue.1
, pp. 153-208
-
-
Takai, Y.1
Sasaki, T.2
Matozaki, T.3
-
103
-
-
84863790444
-
A big new job for small GTPases
-
Carmena, A. A big new job for small GTPases. Small GTPases, 2012, 3(3), 159-162.
-
(2012)
Small GTPases
, vol.3
, Issue.3
, pp. 159-162
-
-
Carmena, A.1
-
104
-
-
0034104590
-
The Ras branch of small GTPases: Ras family members don't fall far from the tree
-
Reuther, G.W.; Der, C.J. The Ras branch of small GTPases: Ras family members don't fall far from the tree. Curr. Opin. Cell. Biol., 2000, 12(2), 157-165.
-
(2000)
Curr. Opin. Cell. Biol.
, vol.12
, Issue.2
, pp. 157-165
-
-
Reuther, G.W.1
Der, C.J.2
-
105
-
-
60849124225
-
Pyk2 mediates endothelin-1 signaling via p130Cas/BCAR3 cascade and regulates human glomerular mesangial cell adhesion and spreading
-
Rufanova, V.A.; Alexanian, A.; Wakatsuki, T.; Lerner, A.; Sorokin, A. Pyk2 mediates endothelin-1 signaling via p130Cas/BCAR3 cascade and regulates human glomerular mesangial cell adhesion and spreading. J. Cell Physiol., 2009, 219(1), 45-56.
-
(2009)
J. Cell Physiol.
, vol.219
, Issue.1
, pp. 45-56
-
-
Rufanova, V.A.1
Alexanian, A.2
Wakatsuki, T.3
Lerner, A.4
Sorokin, A.5
-
106
-
-
53449089229
-
Prostaglandin E2 inhibits specific lung fibroblast functions via selective actions of PKA and Epac-1
-
Huang, S.K.; Wettlaufer, S.H.; Chung, J.; Peters-Golden, M. Prostaglandin E2 inhibits specific lung fibroblast functions via selective actions of PKA and Epac-1. Am. J. Respir. Cell Mol. Biol., 2008, 39(4), 482-489.
-
(2008)
Am. J. Respir. Cell Mol. Biol.
, vol.39
, Issue.4
, pp. 482-489
-
-
Huang, S.K.1
Wettlaufer, S.H.2
Chung, J.3
Peters-Golden, M.4
-
107
-
-
0035186810
-
Identification of up-regulated Ras-like GTPase, Rap1b, by suppression subtractive hybridization
-
Lin, S.; Chugh, S.; Pan, X.; Wallner, E.I.; Wada, J.; Kanwar, Y.S. Identification of up-regulated Ras-like GTPase, Rap1b, by suppression subtractive hybridization. Kidney Int., 2001, 60(6), 2129-2141.
-
(2001)
Kidney Int
, vol.60
, Issue.6
, pp. 2129-2141
-
-
Lin, S.1
Chugh, S.2
Pan, X.3
Wallner, E.I.4
Wada, J.5
Kanwar, Y.S.6
-
108
-
-
0036215771
-
Renal gene expression in embryonic and newborn diabetic mice
-
Wallner, E.I.; Wada, J.; Lin, S.; Pan, X.; Reddy, J.K.; Chugh, S.S.; Kanwar, Y.S. Renal gene expression in embryonic and newborn diabetic mice. Exp. Nephrol., 2002, 10(2), 130-138.
-
(2002)
Exp. Nephrol.
, vol.10
, Issue.2
, pp. 130-138
-
-
Wallner, E.I.1
Wada, J.2
Lin, S.3
Pan, X.4
Reddy, J.K.5
Chugh, S.S.6
Kanwar, Y.S.7
-
109
-
-
0036829908
-
High glucose stimulates synthesis of fibronectin via a novel protein kinase C, Rap1b, and BRaf signaling pathway
-
Lin, S.; Sahai, A.; Chugh, S.S.; Pan, X.; Wallner, E.I.; Danesh, F.R.; Lomasney, J.W.; Kanwar, Y.S. High glucose stimulates synthesis of fibronectin via a novel protein kinase C, Rap1b, and BRaf signaling pathway. J. Biol. Chem., 2002, 277(44), 41725- 41735.
-
(2002)
J. Biol. Chem.
, vol.277
, Issue.44
, pp. 41725-41735
-
-
Lin, S.1
Sahai, A.2
Chugh, S.S.3
Pan, X.4
Wallner, E.I.5
Danesh, F.R.6
Lomasney, J.W.7
Kanwar, Y.S.8
-
110
-
-
84897845228
-
Rap1 ameliorates renal tubular injury in diabetic nephropathy
-
Xiao, L.; Zhu, X.; Yang, S.; Liu, F.; Zhou, Z.; Zhan, M.; Xie, P.; Zhang, D.; Li, J.; Song, P.; Kanwar, Y.S.; Sun, L.Rap1 ameliorates renal tubular injury in diabetic nephropathy. Diabetes, 2014, 63(4), 1366-1380.
-
(2014)
Diabetes
, vol.63
, Issue.4
, pp. 1366-1380
-
-
Xiao, L.1
Zhu, X.2
Yang, S.3
Liu, F.4
Zhou, Z.5
Zhan, M.6
Xie, P.7
Zhang, D.8
Li, J.9
Song, P.10
Kanwar, Y.S.11
Sun, L.12
-
111
-
-
57149107838
-
Rap1b GTPase ameliorates glucose-induced mitochondrial dysfunction
-
Sun, L.; Xie, P.; Wada, J.; Kashihara, N.; Liu, F.Y.; Zhao, Y.; Kumar, D.; Chugh, S.S.; Danesh, F.R.; Kanwar, Y.S. Rap1b GTPase ameliorates glucose-induced mitochondrial dysfunction. J. Am. Soc. Nephrol., 2008, 19(12), 2293-2301.
-
(2008)
J. Am. Soc. Nephrol.
, vol.19
, Issue.12
, pp. 2293-2301
-
-
Sun, L.1
Xie, P.2
Wada, J.3
Kashihara, N.4
Liu, F.Y.5
Zhao, Y.6
Kumar, D.7
Chugh, S.S.8
Danesh, F.R.9
Kanwar, Y.S.10
-
112
-
-
33646501513
-
Ras modulation of superoxide activates ERKdependent fibronectin expression in diabetes-induced renal injuries
-
Lin, C.L.; Wang, F.S.; Kuo, Y.R.; Huang, Y.T.; Huang, H.C.; Sun, Y.C.; Kuo, Y.H. Ras modulation of superoxide activates ERKdependent fibronectin expression in diabetes-induced renal injuries. Kidney Int., 2006, 69(9), 1593-1600.
-
(2006)
Kidney Int.
, vol.69
, Issue.9
, pp. 1593-1600
-
-
Lin, C.L.1
Wang, F.S.2
Kuo, Y.R.3
Huang, Y.T.4
Huang, H.C.5
Sun, Y.C.6
Kuo, Y.H.7
-
113
-
-
0141960264
-
Phosphatidylinositol 3'-kinase-dependent activation of renal mesangial cell Ki-Ras and ERK by advanced glycation end products
-
Xu, D.; Kyriakis, J.M. Phosphatidylinositol 3'-kinase-dependent activation of renal mesangial cell Ki-Ras and ERK by advanced glycation end products. J. Biol. Chem., 2003, 278(41), 39349- 39355.
-
(2003)
J. Biol. Chem.
, vol.278
, Issue.41
, pp. 39349-39355
-
-
Xu, D.1
Kyriakis, J.M.2
-
114
-
-
84900801528
-
The Ras GTPase-activating-like protein IQGAP1 is downregulated in human diabetic nephropathy and associated with ERK1/2 pathway activation
-
Zhou, H.; Yao, C.; Bian, A.; Qian, J.; Zhao, X.; Zhao, Y.; Wang, W.; Xing, C. The Ras GTPase-activating-like protein IQGAP1 is downregulated in human diabetic nephropathy and associated with ERK1/2 pathway activation. Mol. Cell Biochem., 2014, 391(1-2), 21-25.
-
(2014)
Mol. Cell Biochem.
, vol.391
, Issue.1-2
, pp. 21-25
-
-
Zhou, H.1
Yao, C.2
Bian, A.3
Qian, J.4
Zhao, X.5
Zhao, Y.6
Wang, W.7
Xing, C.8
-
115
-
-
79851508434
-
Rho kinase inhibition in diabetic nephropathy
-
Komers, R. Rho kinase inhibition in diabetic nephropathy. Curr. Opin. Nephrol. Hypertens., 2011, 20(1), 77-83.
-
(2011)
Curr. Opin. Nephrol. Hypertens.
, vol.20
, Issue.1
, pp. 77-83
-
-
Komers, R.1
-
116
-
-
84865343393
-
Cell cycle regulation of Rho signaling pathways
-
David, M.; Petit, D.; Bertoglio, J. Cell cycle regulation of Rho signaling pathways. Cell Cycle, 2012, 11(16), 3003-3010.
-
(2012)
Cell Cycle
, vol.11
, Issue.16
, pp. 3003-3010
-
-
David, M.1
Petit, D.2
Bertoglio, J.3
-
117
-
-
34547666918
-
Rho kinase (ROCK) inhibitors
-
Liao, J.K.; Seto, M.; Noma, K. Rho kinase (ROCK) inhibitors. J. Cardiovasc. Pharmacol., 2007, 50(1), 17-24.
-
(2007)
J. Cardiovasc. Pharmacol.
, vol.50
, Issue.1
, pp. 17-24
-
-
Liao, J.K.1
Seto, M.2
Noma, K.3
-
118
-
-
84884680414
-
Rho kinase inhibition in diabetic kidney disease
-
Komers, R. Rho kinase inhibition in diabetic kidney disease. Br. J. Clin. Pharmacol., 2013, 76(4), 551-559.
-
(2013)
Br. J. Clin. Pharmacol.
, vol.76
, Issue.4
, pp. 551-559
-
-
Komers, R.1
-
119
-
-
40949113247
-
Rho kinase inhibition: A new approach for treating diabetic nephropathy?
-
Bach, L.A. Rho kinase inhibition: A new approach for treating diabetic nephropathy? Diabetes, 2008, 57(3), 532-533.
-
(2008)
Diabetes
, vol.57
, Issue.3
, pp. 532-533
-
-
Bach, L.A.1
-
120
-
-
48249141108
-
RhoA/Rho-kinase contribute to the pathogenesis of diabetic renal disease
-
Peng, F.; Wu, D.; Gao, B.; Ingram, A.J.; Zhang, B.; Chorneyko, K.; McKenzie, R.; Krepinsky, J.C. RhoA/Rho-kinase contribute to the pathogenesis of diabetic renal disease. Diabetes, 2008, 57(6), 1683- 1692.
-
(2008)
Diabetes
, vol.57
, Issue.6
, pp. 1683-1692
-
-
Peng, F.1
Wu, D.2
Gao, B.3
Ingram, A.J.4
Zhang, B.5
Chorneyko, K.6
McKenzie, R.7
Krepinsky, J.C.8
-
121
-
-
84859894934
-
The effect of fasudil via Rho/ROCK signaling pathway on the inflammation and fibrosis in human mesangial cells in high glucose medium
-
Ma, D.W.; Wang, Q.Y.; Ma, X.Y.; Li, J.; Guan, Q.H.; Fu, Y. The effect of fasudil via Rho/ROCK signaling pathway on the inflammation and fibrosis in human mesangial cells in high glucose medium. Zhonghua Nei Ke Za Zhi, 2011, 50(7), 580-584.
-
(2011)
Zhonghua Nei Ke Za Zhi
, vol.50
, Issue.7
, pp. 580-584
-
-
Ma, D.W.1
Wang, Q.Y.2
Ma, X.Y.3
Li, J.4
Guan, Q.H.5
Fu, Y.6
-
122
-
-
84870261225
-
Effects of inhibiting RhoA by Stealth RNA on high glucoseinduced RhoA/ROCK signaling pathway in human mesangial cells
-
Ma, D.W.; Wang, Q.Y.; Chen, Q.G.; Wu, D.; Wang, J.; Hou, L.L. Effects of inhibiting RhoA by Stealth RNA on high glucoseinduced RhoA/ROCK signaling pathway in human mesangial cells. Zhonghua Yi Xue Za Zhi, 2011, 91(20), 1417-1421.
-
(2011)
Zhonghua Yi Xue Za Zhi
, vol.91
, Issue.20
, pp. 1417-1421
-
-
Ma, D.W.1
Wang, Q.Y.2
Chen, Q.G.3
Wu, D.4
Wang, J.5
Hou, L.L.6
-
123
-
-
84875053382
-
Activation of RhoA/ROCK regulates NF-kappaB signaling pathway in experimental diabetic nephropathy
-
Xie, X.; Peng, J.; Chang, X.; Huang, K.; Huang, J.; Wang, S.; Shen, X.; Liu, P.; Huang, H. Activation of RhoA/ROCK regulates NF-kappaB signaling pathway in experimental diabetic nephropathy. Mol. Cell Endocrinol., 2013, 369(1-2), 86-97.
-
(2013)
Mol. Cell Endocrinol.
, vol.369
, Issue.1-2
, pp. 86-97
-
-
Xie, X.1
Peng, J.2
Chang, X.3
Huang, K.4
Huang, J.5
Wang, S.6
Shen, X.7
Liu, P.8
Huang, H.9
-
124
-
-
84879999943
-
Fasudil inhibits epithelial- myofibroblast transdifferentiation of human renal tubular epithelial HK-2 cells induced by high glucose
-
Tokyo
-
Gu, L.; Gao, Q.; Ni, L.; Wang, M.; Shen, F. Fasudil inhibits epithelial- myofibroblast transdifferentiation of human renal tubular epithelial HK-2 cells induced by high glucose. Chem. Pharm. Bull. (Tokyo)., 2013, 61(7), 688-694.
-
(2013)
Chem. Pharm. Bull.
, vol.61
, Issue.7
, pp. 688-694
-
-
Gu, L.1
Gao, Q.2
Ni, L.3
Wang, M.4
Shen, F.5
-
125
-
-
40949137434
-
Targeting of RhoA/ROCK signaling ameliorates progression of diabetic nephropathy independent of glucose control
-
Kolavennu, V.; Zeng, L.; Peng, H.; Wang, Y.; Danesh, F.R. Targeting of RhoA/ROCK signaling ameliorates progression of diabetic nephropathy independent of glucose control. Diabetes, 2008, 57(3), 714-723.
-
(2008)
Diabetes
, vol.57
, Issue.3
, pp. 714-723
-
-
Kolavennu, V.1
Zeng, L.2
Peng, H.3
Wang, Y.4
Danesh, F.R.5
-
126
-
-
33947364443
-
A Rho-kinase inhibitor, fasudil, prevents development of diabetes and nephropathy in insulin-resistant diabetic rats
-
Kikuchi, Y.; Yamada, M.; Imakiire, T.; Kushiyama, T.; Higashi, K.; Hyodo, N.; Yamamoto, K.; Oda, T.; Suzuki, S.; Miura, S. A Rho-kinase inhibitor, fasudil, prevents development of diabetes and nephropathy in insulin-resistant diabetic rats. J. Endocrinol., 2007, 192(3), 595-603.
-
(2007)
J. Endocrinol.
, vol.192
, Issue.3
, pp. 595-603
-
-
Kikuchi, Y.1
Yamada, M.2
Imakiire, T.3
Kushiyama, T.4
Higashi, K.5
Hyodo, N.6
Yamamoto, K.7
Oda, T.8
Suzuki, S.9
Miura, S.10
-
127
-
-
84893749273
-
Benidipine protects kidney through inhibiting ROCK1 activity and reducing the epitheliummesenchymal transdifferentiation in type 1 diabetic rats
-
Wu, G.; Xu, M.; Xu, K.; Hu, Y. Benidipine protects kidney through inhibiting ROCK1 activity and reducing the epitheliummesenchymal transdifferentiation in type 1 diabetic rats. J. Diabetes Res., 2013, 2013, 174526.
-
(2013)
J. Diabetes Res.
, vol.2013
, pp. 174526
-
-
Wu, G.1
Xu, M.2
Xu, K.3
Hu, Y.4
-
128
-
-
84882766934
-
Berberine ameliorates experimental diabetes-induced renal inflammation and fibronectin by inhibiting activation of RhoA/ROCK signaling
-
Xie, X.; Chang, X.; Chen, L.; Huang, K.; Huang, J.; Wang, S.; Shen, X.; Liu, P.; Huang, H. Berberine ameliorates experimental diabetes-induced renal inflammation and fibronectin by inhibiting activation of RhoA/ROCK signaling. Mol. Cell Endocrinol., 2013, 381(1-2), 56-65.
-
(2013)
Mol. Cell Endocrinol.
, vol.381
, Issue.1-2
, pp. 56-65
-
-
Xie, X.1
Chang, X.2
Chen, L.3
Huang, K.4
Huang, J.5
Wang, S.6
Shen, X.7
Liu, P.8
Huang, H.9
-
129
-
-
34250797380
-
The Rho-kinase inhibitor, fasudil, attenuates diabetic nephropathy in streptozotocin-induced diabetic rats
-
Gojo, A.; Utsunomiya, K.; Taniguchi, K.; Yokota, T.; Ishizawa, S.; Kanazawa, Y.; Kurata, H.; Tajima, N. The Rho-kinase inhibitor, fasudil, attenuates diabetic nephropathy in streptozotocin-induced diabetic rats. Eur. J. Pharmacol., 2007, 568(1-3), 242-247.
-
(2007)
Eur. J. Pharmacol.
, vol.568
, Issue.1-3
, pp. 242-247
-
-
Gojo, A.1
Utsunomiya, K.2
Taniguchi, K.3
Yokota, T.4
Ishizawa, S.5
Kanazawa, Y.6
Kurata, H.7
Tajima, N.8
-
130
-
-
0034951422
-
Connective tissue growth factor in tubulointerstitial injury of diabetic nephropathy
-
Wang, S.; Denichilo, M.; Brubaker, C.; Hirschberg, R. Connective tissue growth factor in tubulointerstitial injury of diabetic nephropathy. Kidney Int., 2001, 60(1), 96-105.
-
(2001)
Kidney Int
, vol.60
, Issue.1
, pp. 96-105
-
-
Wang, S.1
Denichilo, M.2
Brubaker, C.3
Hirschberg, R.4
-
131
-
-
84863115180
-
Suppression of microRNA- 29 expression by TGF-beta1 promotes collagen expression and renal fibrosis
-
Wang, B.; Komers, R.; Carew, R.; Winbanks, C.E.; Xu, B.; Herman- Edelstein, M.; Koh, P.; Thomas, M.; Jandeleit-Dahm, K.; Gregorevic, P.; Cooper, M.E.; Kantharidis, P. Suppression of microRNA- 29 expression by TGF-beta1 promotes collagen expression and renal fibrosis. J. Am. Soc. Nephrol., 2012, 23(2), 252- 265.
-
(2012)
J. Am. Soc. Nephrol.
, vol.23
, Issue.2
, pp. 252-265
-
-
Wang, B.1
Komers, R.2
Carew, R.3
Winbanks, C.E.4
Xu, B.5
Herman-Edelstein, M.6
Koh, P.7
Thomas, M.8
Jandeleit-Dahm, K.9
Gregorevic, P.10
Cooper, M.E.11
Kantharidis, P.12
-
132
-
-
84919876366
-
Sphingosine-1-phosphate induces differentiation of cultured renal tubular epithelial cells under Rho kinase activation via the S1P2 receptor
-
Ishizawa, S.; Takahashi-Fujigasaki, J.; Kanazawa, Y.; Matoba, K.; Kawanami, D.; Yokota, T.; Iwamoto, T.; Tajima, N.; Manome, Y.; Utsunomiya, K. Sphingosine-1-phosphate induces differentiation of cultured renal tubular epithelial cells under Rho kinase activation via the S1P2 receptor. Clin. Exp. Nephrol., 2014, 18(6), 844-852.
-
(2014)
Clin. Exp. Nephrol.
, vol.18
, Issue.6
, pp. 844-852
-
-
Ishizawa, S.1
Takahashi-Fujigasaki, J.2
Kanazawa, Y.3
Matoba, K.4
Kawanami, D.5
Yokota, T.6
Iwamoto, T.7
Tajima, N.8
Manome, Y.9
Utsunomiya, K.10
-
133
-
-
0037062481
-
3-Hydroxy-3-methylglutaryl CoA reductase inhibitors prevent high glucose-induced proliferation of mesangial cells via modulation of Rho GTPase/p21 signaling pathway: Implications for diabetic nephropathy
-
Danesh, F.R.; Sadeghi, M.M.; Amro, N.; Philips, C.; Zeng, L.; Lin, S.; Sahai, A.; Kanwar, Y.S. 3-Hydroxy-3-methylglutaryl CoA reductase inhibitors prevent high glucose-induced proliferation of mesangial cells via modulation of Rho GTPase/p21 signaling pathway: Implications for diabetic nephropathy. Proc. Natl. Acad. Sci. U. S. A., 2002, 99(12), 8301-8305.
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, Issue.12
, pp. 8301-8305
-
-
Danesh, F.R.1
Sadeghi, M.M.2
Amro, N.3
Philips, C.4
Zeng, L.5
Lin, S.6
Sahai, A.7
Kanwar, Y.S.8
-
134
-
-
84907684189
-
RhoA/rho kinase signaling reduces connexin43 expression in high glucose-treated glomerular mesangial cells with zonula occludens- 1 involvement
-
Xie, X.; Chen, C.; Huang, K.; Wang, S.; Hao, J.; Huang, J.; Huang, H. RhoA/rho kinase signaling reduces connexin43 expression in high glucose-treated glomerular mesangial cells with zonula occludens- 1 involvement. Exp. Cell Res., 2014, 327(2), 276-286.
-
(2014)
Exp. Cell Res.
, vol.327
, Issue.2
, pp. 276-286
-
-
Xie, X.1
Chen, C.2
Huang, K.3
Wang, S.4
Hao, J.5
Huang, J.6
Huang, H.7
-
135
-
-
84863023552
-
Mitochondrial fission triggered by hyperglycemia is mediated by ROCK1 activation in podocytes and endothelial cells
-
Wang, W.; Wang, Y.; Long, J.; Wang, J.; Haudek, S.B.; Overbeek, P.; Chang, B.H.; Schumacker, P.T.; Danesh, F.R. Mitochondrial fission triggered by hyperglycemia is mediated by ROCK1 activation in podocytes and endothelial cells. Cell Metab., 2012, 15(2), 186-200.
-
(2012)
Cell Metab
, vol.15
, Issue.2
, pp. 186-200
-
-
Wang, W.1
Wang, Y.2
Long, J.3
Wang, J.4
Haudek, S.B.5
Overbeek, P.6
Chang, B.H.7
Schumacker, P.T.8
Danesh, F.R.9
-
136
-
-
0035257013
-
Rab proteins as membrane organizers
-
Zerial, M.; McBride, H. Rab proteins as membrane organizers. Nat. Rev. Mol. Cell Biol., 2001, 2(2), 107-117.
-
(2001)
Nat. Rev. Mol. Cell Biol.
, vol.2
, Issue.2
, pp. 107-117
-
-
Zerial, M.1
McBride, H.2
-
137
-
-
24944502395
-
Diacylglycerol-activated Hmunc13 serves as an effector of the GTPase Rab34
-
Speight, P.; Silverman, M. Diacylglycerol-activated Hmunc13 serves as an effector of the GTPase Rab34. Traffic, 2005, 6(10), 858-865.
-
(2005)
Traffic
, vol.6
, Issue.10
, pp. 858-865
-
-
Speight, P.1
Silverman, M.2
-
138
-
-
70349934685
-
Rab34 and its effector munc13-2 constitute a new pathway modulating protein secretion in the cellular response to hyperglycemia
-
Goldenberg, N.M.; Silverman, M. Rab34 and its effector munc13-2 constitute a new pathway modulating protein secretion in the cellular response to hyperglycemia. Am. J. Physiol. Cell Physiol., 2009, 297(4), C1053-C1058.
-
(2009)
Am. J. Physiol. Cell Physiol.
, vol.297
, Issue.4
, pp. C1053-C1058
-
-
Goldenberg, N.M.1
Silverman, M.2
-
139
-
-
77951622247
-
Potential new therapeutic agents for diabetic kidney disease
-
Turgut, F.; Bolton, W.K. Potential new therapeutic agents for diabetic kidney disease. Am. J. Kidney Dis., 2010, 55(5), 928-940.
-
(2010)
Am. J. Kidney Dis.
, vol.55
, Issue.5
, pp. 928-940
-
-
Turgut, F.1
Bolton, W.K.2
|