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Volumn 327, Issue 2, 2014, Pages 276-286

RhoA/rho kinase signaling reduces connexin43 expression in high glucose-treated glomerular mesangial cells with zonula occludens-1 involvement

Author keywords

Connexin43; F actin; RhoA Rho kinase; Zonula occludens 1

Indexed keywords

CONNEXIN 43; F ACTIN; GLUCOSE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN ZO1; RHO KINASE; SYNAPTOTAGMIN I; CONNEXIN 43 PROTEIN, RAT; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SWEETENING AGENT; TJP1 PROTEIN, RAT;

EID: 84907684189     PISSN: 00144827     EISSN: 10902422     Source Type: Journal    
DOI: 10.1016/j.yexcr.2014.07.019     Document Type: Article
Times cited : (24)

References (44)
  • 1
    • 0032737294 scopus 로고    scopus 로고
    • End-stage renal failure in type 2 diabetes: a medical catastrophe of worldwide dimensions
    • Ritz E., Rychlik I., Locatelli F., Halimi S. End-stage renal failure in type 2 diabetes: a medical catastrophe of worldwide dimensions. Am. J. Kidney Dis. 1999, 34:795-808.
    • (1999) Am. J. Kidney Dis. , vol.34 , pp. 795-808
    • Ritz, E.1    Rychlik, I.2    Locatelli, F.3    Halimi, S.4
  • 2
    • 26944433131 scopus 로고    scopus 로고
    • Linking metabolism and immunology: Diabetic nephropathy is an inflammatory disease
    • Tuttle K.R. Linking metabolism and immunology: Diabetic nephropathy is an inflammatory disease. J. Am. Soc. Nephrol. 2005, 16:1537-1538.
    • (2005) J. Am. Soc. Nephrol. , vol.16 , pp. 1537-1538
    • Tuttle, K.R.1
  • 5
    • 0035575585 scopus 로고    scopus 로고
    • Rho family proteins: coordinating cell responses
    • Ridley A.J. Rho family proteins: coordinating cell responses. Trends Cell Biol. 2001, 11:471-477.
    • (2001) Trends Cell Biol. , vol.11 , pp. 471-477
    • Ridley, A.J.1
  • 6
    • 33646763902 scopus 로고    scopus 로고
    • Rho kinases in cardiovascular physiology and pathophysiology
    • Loirand G., Guerin P., Pacaud P. Rho kinases in cardiovascular physiology and pathophysiology. Circ. Res. 2006, 98:322-334.
    • (2006) Circ. Res. , vol.98 , pp. 322-334
    • Loirand, G.1    Guerin, P.2    Pacaud, P.3
  • 8
    • 0037062481 scopus 로고    scopus 로고
    • 3-Hydroxy-3-methylglutaryl CoA reductase inhibitors prevent high glucose-induced proliferation of mesangial cells via modulation of Rho GTPase/ p21 signaling pathway: implications for diabetic nephropathy
    • Danesh F.R., Sadeghi M.M., Amro N., Philips C., Zeng L., Lin S., Sahai A., Kanwar Y.S. 3-Hydroxy-3-methylglutaryl CoA reductase inhibitors prevent high glucose-induced proliferation of mesangial cells via modulation of Rho GTPase/ p21 signaling pathway: implications for diabetic nephropathy. Proc. Natl. Acad. Sci. USA 2002, 99:8301-8305.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 8301-8305
    • Danesh, F.R.1    Sadeghi, M.M.2    Amro, N.3    Philips, C.4    Zeng, L.5    Lin, S.6    Sahai, A.7    Kanwar, Y.S.8
  • 11
    • 0035991948 scopus 로고    scopus 로고
    • Gap junctions: structure and function (Review)
    • Evans W.H., Martin P.E. Gap junctions: structure and function (Review). Mol. Membr. Biol. 2002, 19:121-136.
    • (2002) Mol. Membr. Biol. , vol.19 , pp. 121-136
    • Evans, W.H.1    Martin, P.E.2
  • 12
    • 36349020799 scopus 로고    scopus 로고
    • Pathophysiological roles of gap junction in glomerular mesangial cells
    • Yao J., Zhu Y., Morioka T., Oite T., Kitamura M. Pathophysiological roles of gap junction in glomerular mesangial cells. J. Membr. Biol. 2007, 217:123-130.
    • (2007) J. Membr. Biol. , vol.217 , pp. 123-130
    • Yao, J.1    Zhu, Y.2    Morioka, T.3    Oite, T.4    Kitamura, M.5
  • 13
    • 33646905626 scopus 로고    scopus 로고
    • Downregulation of connexin 43 expression by high glucose induces senescence in glomerular mesangial cells
    • Zhang X., Chen X., Wu D., Liu W., Wang J., Feng Z., Cai G., Fu B., Hong Q., Du J. Downregulation of connexin 43 expression by high glucose induces senescence in glomerular mesangial cells. J. Am. Soc. Nephrol. 2006, 17:1532-1542.
    • (2006) J. Am. Soc. Nephrol. , vol.17 , pp. 1532-1542
    • Zhang, X.1    Chen, X.2    Wu, D.3    Liu, W.4    Wang, J.5    Feng, Z.6    Cai, G.7    Fu, B.8    Hong, Q.9    Du, J.10
  • 15
    • 79960929748 scopus 로고    scopus 로고
    • Altered gap junctional communication and renal haemodynamics in Zucker fatty rat model of type 2 diabetes
    • Takenaka T., Inoue T., Okada H., Ohno Y., Miyazaki T., Chaston D.J., Hill C.E., Suzuki H. Altered gap junctional communication and renal haemodynamics in Zucker fatty rat model of type 2 diabetes. Diabetologia 2011, 54:2192-2201.
    • (2011) Diabetologia , vol.54 , pp. 2192-2201
    • Takenaka, T.1    Inoue, T.2    Okada, H.3    Ohno, Y.4    Miyazaki, T.5    Chaston, D.J.6    Hill, C.E.7    Suzuki, H.8
  • 16
    • 84863011181 scopus 로고    scopus 로고
    • High glucose-induced hypertrophy of mesangial cells is reversed by connexin43 overexpression via PTEN/Akt/mTOR signaling
    • Liu L., Hu X., Cai G.Y., Lv Y., Zhuo L., Gao J.J., Cui S.Y., Feng Z., Fu B., Chen X.M. High glucose-induced hypertrophy of mesangial cells is reversed by connexin43 overexpression via PTEN/Akt/mTOR signaling. Nephrol. Dial Transplant. 2012, 27:90-100.
    • (2012) Nephrol. Dial Transplant. , vol.27 , pp. 90-100
    • Liu, L.1    Hu, X.2    Cai, G.Y.3    Lv, Y.4    Zhuo, L.5    Gao, J.J.6    Cui, S.Y.7    Feng, Z.8    Fu, B.9    Chen, X.M.10
  • 18
    • 0036204837 scopus 로고    scopus 로고
    • Rho and Rho-kinase (ROCK) signaling in adherens and gap junction assembly in corneal epithelium
    • Anderson S.C., Stone C., Tkach L., SundarRaj N. Rho and Rho-kinase (ROCK) signaling in adherens and gap junction assembly in corneal epithelium. Investig. Ophthalmol. Vis. Sci. 2002, 43:978-986.
    • (2002) Investig. Ophthalmol. Vis. Sci. , vol.43 , pp. 978-986
    • Anderson, S.C.1    Stone, C.2    Tkach, L.3    SundarRaj, N.4
  • 20
    • 84863940824 scopus 로고    scopus 로고
    • Laminin-111 stimulates proliferation of mouse embryonic stem cells through a reduction of gap junctional intercellular communication via RhoA-mediated Cx43 phosphorylation and dissociation of Cx43/ZO-1/drebrin complex
    • Suh H.N., Kim M.O., Han H.J. Laminin-111 stimulates proliferation of mouse embryonic stem cells through a reduction of gap junctional intercellular communication via RhoA-mediated Cx43 phosphorylation and dissociation of Cx43/ZO-1/drebrin complex. Stem Cells Dev. 2012, 21:2058-2070.
    • (2012) Stem Cells Dev. , vol.21 , pp. 2058-2070
    • Suh, H.N.1    Kim, M.O.2    Han, H.J.3
  • 21
    • 4544329815 scopus 로고    scopus 로고
    • Bimodal effect of advanced glycation end products on mesangial cell proliferation is mediated by neutral ceramidase regulation and endogenous sphingolipids
    • Geoffroy K., Wiernsperger N., Lagarde M., El Bawab S. Bimodal effect of advanced glycation end products on mesangial cell proliferation is mediated by neutral ceramidase regulation and endogenous sphingolipids. J. Biol. Chem. 2004, 279:34343-34352.
    • (2004) J. Biol. Chem. , vol.279 , pp. 34343-34352
    • Geoffroy, K.1    Wiernsperger, N.2    Lagarde, M.3    El Bawab, S.4
  • 22
    • 78149410755 scopus 로고    scopus 로고
    • Berberine attenuates lipopolysaccharide-induced extracelluar matrix accumulation and inflammation in rat mesangial cells: Involvement of NF-kappa B signaling pathway
    • Jiang Q., Liu P.Q., Wu X.Q., Liu W.H., Shen X.Y., Lan T.A., Xu S.W., Peng J., Xie X., Huang H.Q. Berberine attenuates lipopolysaccharide-induced extracelluar matrix accumulation and inflammation in rat mesangial cells: Involvement of NF-kappa B signaling pathway. Mol. Cell Endocrinol. 2011, 331:34-40.
    • (2011) Mol. Cell Endocrinol. , vol.331 , pp. 34-40
    • Jiang, Q.1    Liu, P.Q.2    Wu, X.Q.3    Liu, W.H.4    Shen, X.Y.5    Lan, T.A.6    Xu, S.W.7    Peng, J.8    Xie, X.9    Huang, H.Q.10
  • 23
    • 77953537219 scopus 로고    scopus 로고
    • Effects of berberine on matrix accumulation and NF-kappa B signal pathway in alloxan-induced diabetic mice with renal injury
    • Liu W.H., Zhang X.Y., Liu P.Q., Shen X.Y., Lan T.A., Li W.Y., Jiang Q., Xie X., Huang H.Q. Effects of berberine on matrix accumulation and NF-kappa B signal pathway in alloxan-induced diabetic mice with renal injury. Eur. J. Pharmacol. 2010, 638:150-155.
    • (2010) Eur. J. Pharmacol. , vol.638 , pp. 150-155
    • Liu, W.H.1    Zhang, X.Y.2    Liu, P.Q.3    Shen, X.Y.4    Lan, T.A.5    Li, W.Y.6    Jiang, Q.7    Xie, X.8    Huang, H.Q.9
  • 25
    • 84865293359 scopus 로고    scopus 로고
    • Polydatin ameliorates experimental diabetes-induced fibronectin through inhibiting the activation of NF-kappaB signaling pathway in rat glomerular mesangial cells
    • Xie X., Peng J., Huang K., Huang J., Shen X., Liu P., Huang H. Polydatin ameliorates experimental diabetes-induced fibronectin through inhibiting the activation of NF-kappaB signaling pathway in rat glomerular mesangial cells. Mol. Cell Endocrinol. 2012, 362:183-193.
    • (2012) Mol. Cell Endocrinol. , vol.362 , pp. 183-193
    • Xie, X.1    Peng, J.2    Huang, K.3    Huang, J.4    Shen, X.5    Liu, P.6    Huang, H.7
  • 26
    • 77956339397 scopus 로고    scopus 로고
    • Berberine ameliorates renal injury in diabetic C57BL/6 mice: involvement of suppression of SphK-S1P signaling pathway
    • Lan T., Shen X., Liu P., Liu W., Xu S., Xie X., Jiang Q., Li W., Huang H. Berberine ameliorates renal injury in diabetic C57BL/6 mice: involvement of suppression of SphK-S1P signaling pathway. Arch. Biochem. Biophys. 2010, 502:112-120.
    • (2010) Arch. Biochem. Biophys. , vol.502 , pp. 112-120
    • Lan, T.1    Shen, X.2    Liu, P.3    Liu, W.4    Xu, S.5    Xie, X.6    Jiang, Q.7    Li, W.8    Huang, H.9
  • 27
    • 33645457715 scopus 로고    scopus 로고
    • Physiological role of ROCKs in the cardiovascular system
    • Noma K., Oyama N., Liao J.K. Physiological role of ROCKs in the cardiovascular system. Am. J. Physiol.: Cell Physiol. 2006, 290:C661-668.
    • (2006) Am. J. Physiol.: Cell Physiol. , vol.290 , pp. C661-668
    • Noma, K.1    Oyama, N.2    Liao, J.K.3
  • 29
    • 24044554201 scopus 로고    scopus 로고
    • Connexin 43 interacts with zona occludens-1 and -2 proteins in a cell cycle stage-specific manner
    • Singh D., Solan J.L., Taffet S.M., Javier R., Lampe P.D. Connexin 43 interacts with zona occludens-1 and -2 proteins in a cell cycle stage-specific manner. J. Biol. Chem. 2005, 280:30416-30421.
    • (2005) J. Biol. Chem. , vol.280 , pp. 30416-30421
    • Singh, D.1    Solan, J.L.2    Taffet, S.M.3    Javier, R.4    Lampe, P.D.5
  • 30
    • 13144252170 scopus 로고    scopus 로고
    • The gap junction protein connexin43 interacts with the second PDZ domain of the zona occludens-1 protein
    • Giepmans B.N., Moolenaar W.H. The gap junction protein connexin43 interacts with the second PDZ domain of the zona occludens-1 protein. Curr. Biol.: CB 1998, 8:931-934.
    • (1998) Curr. Biol.: CB , vol.8 , pp. 931-934
    • Giepmans, B.N.1    Moolenaar, W.H.2
  • 32
    • 1942503184 scopus 로고    scopus 로고
    • Gap junctions and connexin-interacting proteins
    • Giepmans B.N. Gap junctions and connexin-interacting proteins. Cardiovasc. Res. 2004, 62:233-245.
    • (2004) Cardiovasc. Res. , vol.62 , pp. 233-245
    • Giepmans, B.N.1
  • 33
    • 28644434657 scopus 로고    scopus 로고
    • Zonula occludens-1 alters connexin43 gap junction size and organization by influencing channel accretion
    • Hunter A.W., Barker R.J., Zhu C., Gourdie R.G. Zonula occludens-1 alters connexin43 gap junction size and organization by influencing channel accretion. Mol. Biol. Cell 2005, 16:5686-5698.
    • (2005) Mol. Biol. Cell , vol.16 , pp. 5686-5698
    • Hunter, A.W.1    Barker, R.J.2    Zhu, C.3    Gourdie, R.G.4
  • 34
    • 80755140583 scopus 로고    scopus 로고
    • Increased interaction of connexin43 with zonula occludens-1 during inhibition of gap junctions by G protein-coupled receptor agonists
    • Tence M., Ezan P., Amigou E., Giaume C. Increased interaction of connexin43 with zonula occludens-1 during inhibition of gap junctions by G protein-coupled receptor agonists. Cell Signal 2012, 24:86-98.
    • (2012) Cell Signal , vol.24 , pp. 86-98
    • Tence, M.1    Ezan, P.2    Amigou, E.3    Giaume, C.4
  • 35
    • 0037155043 scopus 로고    scopus 로고
    • Increased association of ZO-1 with connexin43 during remodeling of cardiac gap junctions
    • Barker R.J., Price R.L., Gourdie R.G. Increased association of ZO-1 with connexin43 during remodeling of cardiac gap junctions. Circ. Res. 2002, 90:317-324.
    • (2002) Circ. Res. , vol.90 , pp. 317-324
    • Barker, R.J.1    Price, R.L.2    Gourdie, R.G.3
  • 36
    • 2942683207 scopus 로고    scopus 로고
    • A proposed role for ZO-1 in targeting connexin 43 gap junctions to the endocytic pathway
    • Segretain D., Fiorini C., Decrouy X., Defamie N., Prat J.R., Pointis G. A proposed role for ZO-1 in targeting connexin 43 gap junctions to the endocytic pathway. Biochimie 2004, 86:241-244.
    • (2004) Biochimie , vol.86 , pp. 241-244
    • Segretain, D.1    Fiorini, C.2    Decrouy, X.3    Defamie, N.4    Prat, J.R.5    Pointis, G.6
  • 37
    • 0025789648 scopus 로고
    • Biochemical analysis of connexin43 intracellular transport, phosphorylation, and assembly into gap junctional plaques
    • Musil L.S., Goodenough D.A. Biochemical analysis of connexin43 intracellular transport, phosphorylation, and assembly into gap junctional plaques. J. Cell Biol. 1991, 115:1357-1374.
    • (1991) J. Cell Biol. , vol.115 , pp. 1357-1374
    • Musil, L.S.1    Goodenough, D.A.2
  • 38
    • 0026025267 scopus 로고
    • Turnover and phosphorylation dynamics of connexin43 gap junction protein in cultured cardiac myocytes
    • Laird D.W., Puranam K.L., Revel J.P. Turnover and phosphorylation dynamics of connexin43 gap junction protein in cultured cardiac myocytes. Biochem. J. 1991, 273(Pt. 1):67-72.
    • (1991) Biochem. J. , vol.273 , pp. 67-72
    • Laird, D.W.1    Puranam, K.L.2    Revel, J.P.3
  • 39
    • 0029176855 scopus 로고
    • Gap junction turnover, intracellular trafficking, and phosphorylation of connexin43 in brefeldin A-treated rat mammary tumor cells
    • Laird D.W., Castillo M., Kasprzak L. Gap junction turnover, intracellular trafficking, and phosphorylation of connexin43 in brefeldin A-treated rat mammary tumor cells. J. Cell Biol. 1995, 131:1193-1203.
    • (1995) J. Cell Biol. , vol.131 , pp. 1193-1203
    • Laird, D.W.1    Castillo, M.2    Kasprzak, L.3
  • 40
    • 0023030826 scopus 로고
    • Identification of ZO-1: a high molecular weight polypeptide associated with the tight junction (zonula occludens) in a variety of epithelia
    • Stevenson B.R., Siliciano J.D., Mooseker M.S., Goodenough D.A. Identification of ZO-1: a high molecular weight polypeptide associated with the tight junction (zonula occludens) in a variety of epithelia. J. Cell Biol. 1986, 103:755-766.
    • (1986) J. Cell Biol. , vol.103 , pp. 755-766
    • Stevenson, B.R.1    Siliciano, J.D.2    Mooseker, M.S.3    Goodenough, D.A.4
  • 41
    • 0031893838 scopus 로고    scopus 로고
    • Molecular structure and assembly of the tight junction
    • Denker B.M., Nigam S.K. Molecular structure and assembly of the tight junction. Am. J. Physiol. 1998, 274:F1-9.
    • (1998) Am. J. Physiol. , vol.274 , pp. F1-9
    • Denker, B.M.1    Nigam, S.K.2
  • 42
    • 0032557460 scopus 로고    scopus 로고
    • Direct association of the gap junction protein connexin-43 with ZO-1 in cardiac myocytes
    • Toyofuku T., Yabuki M., Otsu K., Kuzuya T., Hori M., Tada M. Direct association of the gap junction protein connexin-43 with ZO-1 in cardiac myocytes. J. Biol. Chem. 1998, 273:12725-12731.
    • (1998) J. Biol. Chem. , vol.273 , pp. 12725-12731
    • Toyofuku, T.1    Yabuki, M.2    Otsu, K.3    Kuzuya, T.4    Hori, M.5    Tada, M.6
  • 44
    • 0020626968 scopus 로고
    • In vitro, rapid assembly of gap junctions is induced by cytoskeleton disruptors
    • Tadvalkar G., Pinto da Silva P. In vitro, rapid assembly of gap junctions is induced by cytoskeleton disruptors. J. Cell Biol. 1983, 96:1279-1287.
    • (1983) J. Cell Biol. , vol.96 , pp. 1279-1287
    • Tadvalkar, G.1    Pinto da Silva, P.2


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