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Volumn 9, Issue 5, 2014, Pages

TLR4 activation promotes podocyte injury and interstitial fibrosis in diabetic nephropathy

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CD68 ANTIGEN; CHEMOKINE; CYTOKINE; DNA; FIBRONECTIN; GAMMA INTERFERON INDUCIBLE PROTEIN 10; HEAT SHOCK PROTEIN 70; HIGH MOBILITY GROUP B1 PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; LIGAND; LYMPHOTOXIN; MONOCYTE CHEMOTACTIC PROTEIN 1; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; COLLAGEN; TLR4 PROTEIN, MOUSE;

EID: 84901303677     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0097985     Document Type: Article
Times cited : (132)

References (42)
  • 2
    • 33845405589 scopus 로고    scopus 로고
    • Inflammation and diabetic nephropathy
    • DOI 10.1007/s11892-006-0080-1
    • Mora C, Navarro JF (2006) Inflammation and diabetic nephropathy. Current diabetes reports 6: 463-468. (Pubitemid 44896406)
    • (2006) Current Diabetes Reports , vol.6 , Issue.6 , pp. 463-468
    • Mora, C.1    Navarro, J.F.2
  • 3
    • 26944433131 scopus 로고    scopus 로고
    • Linking metabolism and immunology: Diabetic nephropathy is an inflammatory disease
    • Tuttle KR (2005) Linking metabolism and immunology: diabetic nephropathy is an inflammatory disease. J Am Soc Nephrol 16: 1537-1538.
    • (2005) J Am Soc Nephrol , vol.16 , pp. 1537-1538
    • Tuttle, K.R.1
  • 4
    • 1642275654 scopus 로고    scopus 로고
    • Signaling Danger: Toll-Like Receptors and their Potential Roles in Kidney Disease
    • DOI 10.1097/01.ASN.0000121781.89599.16
    • Anders HJ, Banas B, Schlondorff D (2004) Signaling danger: toll-like receptors and their potential roles in kidney disease. J Am Soc Nephrol 15: 854-867. (Pubitemid 38375304)
    • (2004) Journal of the American Society of Nephrology , vol.15 , Issue.4 , pp. 854-867
    • Anders, H.-J.1    Banas, B.2    Schlondorff, D.3
  • 10
    • 44049103058 scopus 로고    scopus 로고
    • TLR4 signaling mediates inflammation and tissue injury in nephrotoxicity
    • Zhang B, Ramesh G, Uematsu S, Akira S, Reeves WB (2008) TLR4 signaling mediates inflammation and tissue injury in nephrotoxicity. J Am Soc Nephrol 19: 923-932.
    • (2008) J Am Soc Nephrol , vol.19 , pp. 923-932
    • Zhang, B.1    Ramesh, G.2    Uematsu, S.3    Akira, S.4    Reeves, W.B.5
  • 11
    • 33745817481 scopus 로고    scopus 로고
    • Toll-like receptor 2 agonists exacerbate accelerated nephrotoxic nephritis
    • DOI 10.1681/ASN.2005111167
    • Brown HJ, Sacks SH, Robson MG (2006) Toll-like receptor 2 agonists exacerbate accelerated nephrotoxic nephritis. J Am Soc Nephrol 17: 1931-1939. (Pubitemid 44036177)
    • (2006) Journal of the American Society of Nephrology , vol.17 , Issue.7 , pp. 1931-1939
    • Brown, H.J.1    Sacks, S.H.2    Robson, M.G.3
  • 12
    • 34249884208 scopus 로고    scopus 로고
    • Toll-like receptor 4 ligation on intrinsic renal cells contributes to the induction of antibody-mediated glomerulonephritis via CXCL1 and CXCL2
    • DOI 10.1681/ASN.2006060634
    • Brown HJ, Lock HR, Wolfs TG, Buurman WA, Sacks SH, et al. (2007) Toll-like receptor 4 ligation on intrinsic renal cells contributes to the induction of antibody-mediated glomerulonephritis via CXCL1 and CXCL2. J Am Soc Nephrol 18: 1732-1739. (Pubitemid 46870310)
    • (2007) Journal of the American Society of Nephrology , vol.18 , Issue.6 , pp. 1732-1739
    • Brown, H.J.1    Lock, H.R.2    Wolfs, T.G.A.M.3    Buurman, W.A.4    Sacks, S.H.5    Robson, M.G.6
  • 13
    • 39049157857 scopus 로고    scopus 로고
    • Increased toll-like receptor (TLR) 2 and TLR4 expression in monocytes from patients with type 1 diabetes: Further evidence of a proinflammatory state
    • DOI 10.1210/jc.2007-2185
    • Devaraj S, Dasu MR, Rockwood J, Winter W, Griffen SC, et al. (2008) Increased toll-like receptor (TLR) 2 and TLR4 expression in monocytes from patients with type 1 diabetes: further evidence of a proinflammatory state. J Clin Endocrinol Metab 93: 578-583. (Pubitemid 351240834)
    • (2008) Journal of Clinical Endocrinology and Metabolism , vol.93 , Issue.2 , pp. 578-583
    • Devaraj, S.1    Dasu, M.R.2    Rockwood, J.3    Winter, W.4    Griffen, S.C.5    Jialal, I.6
  • 14
    • 77953060025 scopus 로고    scopus 로고
    • Increased toll-like receptor (TLR) activation and TLR ligands in recently diagnosed type 2 diabetic subjects
    • Dasu MR, Devaraj S, Park S, Jialal I (2010) Increased toll-like receptor (TLR) activation and TLR ligands in recently diagnosed type 2 diabetic subjects. Diabetes care 33: 861-868.
    • (2010) Diabetes Care , vol.33 , pp. 861-868
    • Dasu, M.R.1    Devaraj, S.2    Park, S.3    Jialal, I.4
  • 15
    • 84862922902 scopus 로고    scopus 로고
    • Toll-like receptor 4 promotes tubular inflammation in diabetic nephropathy
    • Lin M, Yiu WH, Wu HJ, Chan LY, Leung JC, et al. (2012) Toll-like receptor 4 promotes tubular inflammation in diabetic nephropathy. J Am Soc Nephrol 23: 86-102.
    • (2012) J Am Soc Nephrol , vol.23 , pp. 86-102
    • Lin, M.1    Yiu, W.H.2    Wu, H.J.3    Chan, L.Y.4    Leung, J.C.5
  • 16
    • 80051544616 scopus 로고    scopus 로고
    • Knockout of toll-like receptor-2 attenuates both the proinflammatory state of diabetes and incipient diabetic nephropathy
    • Devaraj S, Tobias P, Kasinath BS, Ramsamooj R, Afify A, et al. (2011) Knockout of toll-like receptor-2 attenuates both the proinflammatory state of diabetes and incipient diabetic nephropathy. Arteriosclerosis, thrombosis, and vascular biology 31: 1796-1804.
    • (2011) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.31 , pp. 1796-1804
    • Devaraj, S.1    Tobias, P.2    Kasinath, B.S.3    Ramsamooj, R.4    Afify, A.5
  • 17
    • 79960892180 scopus 로고    scopus 로고
    • Knockout of toll-like receptor-4 attenuates the pro-inflammatory state of diabetes
    • Devaraj S, Tobias P, Jialal I (2011) Knockout of toll-like receptor-4 attenuates the pro-inflammatory state of diabetes. Cytokine 55: 441-445.
    • (2011) Cytokine , vol.55 , pp. 441-445
    • Devaraj, S.1    Tobias, P.2    Jialal, I.3
  • 18
    • 84877048917 scopus 로고    scopus 로고
    • The TLR4 antagonist CRX-526 protects against advanced diabetic nephropathy
    • Lin M, Yiu WH, Li RX, Wu HJ, Wong DW, et al. (2013) The TLR4 antagonist CRX-526 protects against advanced diabetic nephropathy. Kidney Int.
    • (2013) Kidney Int
    • Lin, M.1    Yiu, W.H.2    Li, R.X.3    Wu, H.J.4    Wong, D.W.5
  • 19
    • 84866381264 scopus 로고    scopus 로고
    • Exacerbation of diabetic nephropathy by hyperlipidaemia is mediated by Toll-like receptor 4 in mice
    • Kuwabara T, Mori K, Mukoyama M, Kasahara M, Yokoi H, et al. (2012) Exacerbation of diabetic nephropathy by hyperlipidaemia is mediated by Toll-like receptor 4 in mice. Diabetologia 55: 2256-2266.
    • (2012) Diabetologia , vol.55 , pp. 2256-2266
    • Kuwabara, T.1    Mori, K.2    Mukoyama, M.3    Kasahara, M.4    Yokoi, H.5
  • 20
    • 84878446398 scopus 로고    scopus 로고
    • Renal protective effects of toll-like receptor 4 signaling blockade in type 2 diabetic mice
    • Cha JJ, Hyun YY, Lee MH, Kim JE, Nam DH, et al. (2013) Renal protective effects of toll-like receptor 4 signaling blockade in type 2 diabetic mice. Endocrinology 154: 2144-2155.
    • (2013) Endocrinology , vol.154 , pp. 2144-2155
    • Cha, J.J.1    Hyun, Y.Y.2    Lee, M.H.3    Kim, J.E.4    Nam, D.H.5
  • 22
    • 44349126743 scopus 로고    scopus 로고
    • TLR4 links podocytes with the innate immune system to mediate glomerular injury
    • Banas MC, Banas B, Hudkins KL, Wietecha TA, Iyoda M, et al. (2008) TLR4 links podocytes with the innate immune system to mediate glomerular injury. J Am Soc Nephrol 19: 704-713.
    • (2008) J Am Soc Nephrol , vol.19 , pp. 704-713
    • Banas, M.C.1    Banas, B.2    Hudkins, K.L.3    Wietecha, T.A.4    Iyoda, M.5
  • 24
    • 0001503778 scopus 로고
    • A principle for counting tissue structures on random sections
    • Weibel ER, Gomez DM (1962) A principle for counting tissue structures on random sections. J Appl Physiol 17: 343-348.
    • (1962) J Appl Physiol , vol.17 , pp. 343-348
    • Weibel, E.R.1    Gomez, D.M.2
  • 26
    • 0022469201 scopus 로고
    • Morphometric analysis of cellular infiltration assessed by monoclonal antibody labeling in sequential human renal allograft biopsies
    • McWhinnie DL, Thompson JF, Taylor HM, Chapman JR, Bolton EM, et al. (1986) Morphometric analysis of cellular infiltration assessed by monoclonal antibody labeling in sequential human renal allograft biopsies. Transplantation 42: 352-358. (Pubitemid 16005759)
    • (1986) Transplantation , vol.42 , Issue.4 , pp. 352-358
    • McWhinnie, D.L.1    Thompson, J.F.2    Taylor, H.M.3
  • 27
    • 67650655975 scopus 로고    scopus 로고
    • Antibody blockade of c-fms suppresses the progression of inflammation and injury in early diabetic nephropathy in obese db/db mice
    • Lim AK, Ma FY, Nikolic-Paterson DJ, Thomas MC, Hurst LA, et al. (2009) Antibody blockade of c-fms suppresses the progression of inflammation and injury in early diabetic nephropathy in obese db/db mice. Diabetologia 52: 1669-1679.
    • (2009) Diabetologia , vol.52 , pp. 1669-1679
    • Lim, A.K.1    Ma, F.Y.2    Nikolic-Paterson, D.J.3    Thomas, M.C.4    Hurst, L.A.5
  • 32
    • 0036317169 scopus 로고    scopus 로고
    • The early natural history of nephropathy in type 1 diabetes: I. Study design and baseline characteristics of the study participants
    • Mauer M, Drummond K (2002) The early natural history of nephropathy in type 1 diabetes: I. Study design and baseline characteristics of the study participants. Diabetes 51: 1572-1579. (Pubitemid 34826627)
    • (2002) Diabetes , vol.51 , Issue.5 , pp. 1572-1579
    • Mauer, M.1    Drummond, K.2
  • 33
    • 0035210580 scopus 로고    scopus 로고
    • Caught flat-footed: Podocyte damage and the molecular bases of focal glomerulosclerosis
    • Kerjaschki D (2001) Caught flat-footed: podocyte damage and the molecular bases of focal glomerulosclerosis. The Journal of clinical investigation 108: 1583-1587.
    • (2001) The Journal of Clinical Investigation , vol.108 , pp. 1583-1587
    • Kerjaschki, D.1
  • 34
    • 0032710966 scopus 로고    scopus 로고
    • Podocyte number predicts long-term urinary albumin excretion in Pima Indians with Type II diabetes and microalbuminuria
    • DOI 10.1007/s001250051447
    • Meyer TW, Bennett PH, Nelson RG (1999) Podocyte number predicts long-term urinary albumin excretion in Pima Indians with Type II diabetes and microalbuminuria. Diabetologia 42: 1341-1344. (Pubitemid 29500971)
    • (1999) Diabetologia , vol.42 , Issue.11 , pp. 1341-1344
    • Meyer, T.W.1    Bennett, P.H.2    Nelson, R.G.3
  • 35
    • 48249127629 scopus 로고    scopus 로고
    • From fibrosis to sclerosis: Mechanisms of glomerulosclerosis in diabetic nephropathy
    • Qian Y, Feldman E, Pennathur S, Kretzler M, Brosius FC, 3rd (2008) From fibrosis to sclerosis: mechanisms of glomerulosclerosis in diabetic nephropathy. Diabetes 57: 1439-1445.
    • (2008) Diabetes , vol.57 , pp. 1439-1445
    • Qian, Y.1    Feldman, E.2    Pennathur, S.3    Kretzler, M.4    Brosius III, F.C.5
  • 37
    • 77955604860 scopus 로고    scopus 로고
    • TLR4 promotes fibrosis but attenuates tubular damage in progressive renal injury
    • Pulskens WP, Rampanelli E, Teske GJ, Butter LM, Claessen N, et al. (2010) TLR4 promotes fibrosis but attenuates tubular damage in progressive renal injury. J Am Soc Nephrol 21: 1299-1308.
    • (2010) J Am Soc Nephrol , vol.21 , pp. 1299-1308
    • Pulskens, W.P.1    Rampanelli, E.2    Teske, G.J.3    Butter, L.M.4    Claessen, N.5
  • 38
    • 0028109801 scopus 로고
    • Transforming growth factor beta in tissue fibrosis
    • DOI 10.1056/NEJM199411103311907
    • Border WA, Noble NA (1994) Transforming growth factor beta in tissue fibrosis. N Engl J Med 331: 1286-1292. (Pubitemid 24333194)
    • (1994) New England Journal of Medicine , vol.331 , Issue.19 , pp. 1286-1292
    • Border, W.A.1    Noble, N.A.2
  • 40
    • 79551599216 scopus 로고    scopus 로고
    • The protective role of Smad7 in diabetic kidney disease: Mechanism and therapeutic potential
    • Chen HY, Huang XR, Wang W, Li JH, Heuchel RL, et al. (2011) The protective role of Smad7 in diabetic kidney disease: mechanism and therapeutic potential. Diabetes 60: 590-601.
    • (2011) Diabetes , vol.60 , pp. 590-601
    • Chen, H.Y.1    Huang, X.R.2    Wang, W.3    Li, J.H.4    Heuchel, R.L.5
  • 41
    • 34547967661 scopus 로고    scopus 로고
    • Role of macrophages in complications of type 2 diabetes
    • Tesch GH (2007) Role of macrophages in complications of type 2 diabetes. Clin Exp Pharmacol Physiol 34: 1016-1019.
    • (2007) Clin Exp Pharmacol Physiol , vol.34 , pp. 1016-1019
    • Tesch, G.H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.