Effects of high glucose on integrin activity and fibronectin matrix assembly by mesangial cells

Molecular Biology of the Cell

Volumn 25, Issue 16, 2014, Pages 2342-2350

  Miller, Charles G ^a   Pozzi, Ambra ^b,c,d   Zent, Roy ^b,c,d   Schwarzbauer, Jean E ^a  

^a PRINCETON UNIVERSITY   (United States)

^b VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^c VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA1 INTEGRIN; COLLAGEN TYPE 4; FIBRONECTIN; GLUCOSE; PROTEIN KINASE C; INTEGRIN; SCLEROPROTEIN;

ANIMAL CELL; ARTICLE; CELL ADHESION; CELL CULTURE; CELL INTERACTION; CELL SURFACE; CONTROLLED STUDY; DIABETIC NEPHROPATHY; ENDOTHELIUM CELL; EXTRACELLULAR MATRIX; IMMUNOFLUORESCENCE; MESANGIUM CELL; MOUSE; NONHUMAN; PODOCYTE; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; HUMAN; METABOLISM; SIGNAL TRANSDUCTION;

CELLS, CULTURED; COLLAGEN TYPE IV; DIABETIC NEPHROPATHIES; EXTRACELLULAR MATRIX; EXTRACELLULAR MATRIX PROTEINS; FIBRONECTINS; GLUCOSE; HUMANS; INTEGRINS; MESANGIAL CELLS; SIGNAL TRANSDUCTION;

EID: 84905980583     PISSN: 10591524     EISSN: 19394586     Source Type: Journal    
DOI: 10.1091/mbc.E14-03-0800     Document Type: Article

References (66)

1. Abboud HE (2012). Mesangial cell biology. Exp Cell Res 318, 979-985.
2. Aguirre KM, McCormick RJ, Schwarzbauer JE (1994). Fibronectin self-association is mediated by complementary sites within the amino-terminal one-third of the molecule. J Biol Chem 269, 27863-27868. (Pubitemid 24354509)
3. Aumailley M, Timpl R (1986). Attachment of cells to basement membrane collagen type IV. J Cell Biol 103, 1569-1575. (Pubitemid 17174179)
4. Ayo SH, Radnik RA, Garoni JA, Glass WF, Kreisberg JI (1990). High glucose causes an increase in extracellular matrix proteins in cultured mesangial cells. Am J Pathol 136, 1339-1348. (Pubitemid 20210333)
5. Ayo SH, Radnik R, Garoni JA, Troyer DA, Kreisberg JI (1991). High glucose increases diacylglycerol mass and activates protein kinase C in mesangial cell cultures. Am J Physiol 261, F571-F577.
6. Baylis C, Corman B (1998). The aging kidney: insights from experimental studies. J Am Soc Nephrol 9, 699-709. (Pubitemid 28186060)
7. Bazzoni G, Shih DT, Buck CA, Hemler ME (1995). Monoclonal antibody 9EG7 defines a novel beta 1 integrin epitope induced by soluble ligand and manganese, but inhibited by calcium. J Biol Chem 270, 25570-25577.
8. Borza CM et al. (2012). Inhibition of integrin α2β1 ameliorates glomerular injury. J Am Soc Nephrol 23, 1027-1038.
9. Brownlee M (2001). Biochemistry and molecular cell biology of diabetic complications. Nature 414, 813-820.
10. Chen S, Chakrabarti R, Keats EC, Chen M, Chakrabarti S, Khan ZA (2012). Regulation of vascular endothelial growth factor expression by extra domain B segment of fibronectin in endothelial cells. Invest Ophthalmol Vis Sci 53, 8333-8343.
11. Chen X et al. (2007). Integrin alpha1beta1 controls reactive oxygen species synthesis by negatively regulating epidermal growth factor receptor-mediated Rac activation. Mol Cell Biol 27, 3313-3326. (Pubitemid 46685210)
12. Chen X, Moeckel G, Morrow JD, Cosgrove D, Harris RC, Fogo AB, Zent R, Pozzi A (2004). Lack of integrin alpha1beta1 leads to severe glomerulosclerosis after glomerular injury. Am J Pathol 165, 617-630. (Pubitemid 38971391)
13. Chiang H-Y, Korshunov VA, Serour A, Shi F, Sottile J (2009). Fibronectin is an important regulator of flow-induced vascular remodeling. Arterioscler Thromb Vasc Biol 29, 1074-1079.
14. Cifuni SM, Wagner DD, Bergmeier W (2008). CalDAG-GEFI and protein kinase C represent alternative pathways leading to activation of integrin alphaIIbbeta3 in platelets. Blood 112, 1696-1703.
15. Dixon AJ, Burns J, Dunnill MS, McGee JO (1980). Distribution of fibronectin in normal and diseased human kidneys. J Clin Pathol 33, 1021-1028. (Pubitemid 11194193)
16. Engvall E, Ruoslahti E, Miller EJ (1978). Affinity of fibronectin to collagens of different genetic types and to fibrinogen. J Exp Med 147, 1584-1595. (Pubitemid 8372953)
17. Ensenberger MG, Tomasini-Johansson BR, Sottile J, Ozeri V, Hanski E, Mosher DF (2001). Specific interactions between F1 adhesin of Streptococcus pyogenes and N-terminal modules of fibronectin. J Biol Chem 276, 35606-35613.
18. Falk RJ, Scheinman JI, Mauer SM, Michael AF (1983). Polyantigenic expansion of basement membrane constituents in diabetic nephropathy. Diabetes 32 (Suppl 2), 34-39. (Pubitemid 13099680)
19. Gailit J, Ruoslahti E (1988). Regulation of the fibronectin receptor affinity by divalent cations. J Biol Chem 263, 12927-12932.
20. Gardner H, Broberg A, Pozzi A, Laato M, Heino J (1999). Absence of integrin alpha1beta1 in the mouse causes loss of feedback regulation of collagen synthesis in normal and wounded dermis. J Cell Sci 112, 263-272. (Pubitemid 29080649)
21. Hagiwara H, Kaizu K, Uriu K, Noguchi T, Takagi I, Qie YL, Seki T, Ariga T (2003). Expression of type-1 plasminogen activator inhibitor in the kidney of diabetic rat models. Thromb Res 111, 301-309. (Pubitemid 38021951)
22. Haraldsson B, Nyström J, Deen WM (2008). Properties of the glomerular barrier and mechanisms of proteinuria. Physiol Rev 88, 451-487. (Pubitemid 351522745)
23. Hopf M, Göhring W, Mann K, Timpl R (2001). Mapping of binding sites for nidogens, fibulin-2, fibronectin and heparin to different IG modules of perlecan. J Mol Biol 311, 529-541. (Pubitemid 32816587)
24. Huang K, Liu W, Lan T, Xie X, Peng J, Huang J, Wang S, Shen X, Liu P, Huang H (2012). Berberine reduces fibronectin expression by suppressing the S1P-S1P2 receptor pathway in experimental diabetic nephropathy models. PLoS One 7, e43874.
25. Hunt GC, Singh P, Schwarzbauer JE (2012). Endogenous production of fibronectin is required for self-renewal of cultured mouse embryonic stem cells. Exp Cell Res 318, 1820-1831.
26. Hynes RO (1990). Fibronectins, New York: Springer-Verlag.
27. Kadler KE, Hill A, Canty-Laird EG (2008). Collagen fibrillogenesis: fibronectin, integrins, and minor collagens as organizers and nucleators. Curr Opin Cell Biol 20, 495-501.
28. Kagami S, Border WA, Ruoslahti E, Noble NA (1993). Coordinated expression of beta 1 integrins and transforming growth factor-beta-induced matrix proteins in glomerulonephritis. Lab Invest 69, 68-76. (Pubitemid 23222248)
29. Kerjaschki D, Ojha PP, Susani M, Horvat R, Binder S, Hovorka A, Hillemanns P, Pytela R (1989). A beta 1-integrin receptor for fibronectin in human kidney glomeruli. Am J Pathol 134, 481-489. (Pubitemid 19063905)
30. Kim C, Ye F, Ginsberg MH (2011). Regulation of integrin activation. Annu Rev Cell Dev Biol 27, 321-345.
31. Kitsiou PV, Tzinia AK, Stetler-Stevenson WG, Michael AF, Fan W-W, Zhou B, Tsilibary EC (2003). Glucose-induced changes in integrins and matrix-related functions in cultured human glomerular epithelial cells. Am J Physiol Renal Physiol 284, F671-F679. (Pubitemid 36336973)
32. Kolset SO, Reinholt FP, Jenssen T (2012). Diabetic nephropathy and extracellular matrix. J Histochem Cytochem 60, 976-986.
33. Köppel H, Riedl E, Braunagel M, Sauerhoefer S, Ehnert S, Godoy P, Sternik P, Dooley S, Yard BA (2011). L-carnosine inhibits high-glucose-mediated matrix accumulation in human mesangial cells by interfering with TGF-β production and signalling. Nephrol Dial Transplant 26, 3852-3858.
34. Kwoh C, Shannon MB, Miner JH, Shaw A (2006). Pathogenesis of nonimmune glomerulopathies. Annu Rev Pathol 1, 349-374.
35. Lee H-S, Lim CJ, Puzon-McLaughlin W, Shattil SJ, Ginsberg MH (2009). RIAM activates integrins by linking talin to ras GTPase membrane-targeting sequences. J Biol Chem 284, 5119-5127.
36. Leiss M, Beckmann K, Girós A, Costell M, Fässler R (2008). The role of integrin binding sites in fibronectin matrix assembly in vivo. Curr Opin Cell Biol 20, 502-507.
37. Li S, Van Den Diepstraten C, D'Souza SJ, Chan BMC, Pickering JG (2003). Vascular smooth muscle cells orchestrate the assembly of type I collagen via alpha2beta1 integrin, RhoA, and fibronectin polymerization. Am J Pathol 163, 1045-1056. (Pubitemid 37040140)
38. Lin S, Sahai A, Chugh SS, Pan X, Wallner EI, Danesh FR, Lomasney JW, Kanwar YS (2002). High glucose stimulates synthesis of fibronectin via a novel protein kinase C, Rap1b, and B-Raf signaling pathway. J Biol Chem 277, 41725-41735. (Pubitemid 35257480)
39. Mao Y, Schwarzbauer JE (2005). Stimulatory effects of a three-dimensional microenvironment on cell-mediated fibronectin fibrillogenesis. J Cell Sci 118, 4427-4436. (Pubitemid 41556341)
40. Mason RM, Wahab NA (2003). Extracellular matrix metabolism in diabetic nephropathy. J Am Soc Nephrol 14, 1358-1373. (Pubitemid 36519197)
41. Maurer LM, Tomasini-Johansson BR, Ma W, Annis DS, Eickstaedt NL, Ensenberger MG, Satyshur KA, Mosher DF (2010). Extended binding site on fibronectin for the functional upstream domain of protein F1 of Streptococcus pyogenes. J Biol Chem 285, 41087-41099.
42. McKeown-Longo PJ, Mosher DF (1983). Binding of plasma fibronectin to cell layers of human skin fibroblasts. J Cell Biol 97, 466-472.
43. O'Toole TE, Katagiri Y, Faull RJ, Peter K, Tamura R, Quaranta V, Loftus JC, Shattil SJ, Ginsberg MH (1994). Integrin cytoplasmic domains mediate inside-out signal transduction. J Cell Biol 124, 1047-1059. (Pubitemid 24109406)
44. Park J, Seo JY, Ha H (2010). Plasminogen activator inhibitor-1 antisense oligodeoxynucleotides abrogate mesangial fibronectin accumulation. Korean J Physiol Pharmacol 14, 385-390.
45. Pozzi A, Voziyan PA, Hudson BG, Zent R (2009). Regulation of matrix synthesis, remodeling and accumulation in glomerulosclerosis. Curr Pharm Des 15, 1318-1333.
46. Pozzi A, Zent R (2013). Integrins in kidney disease. J Am Soc Nephrol 24, 1034-1039.
47. Reckelhoff JF, Tygart VL, Mitias MM, Walcott JL (1993). STZ-induced diabetes results in decreased activity of glomerular cathepsin and metalloprotease in rats. Diabetes 42, 1425-1432. (Pubitemid 23277198)
48. Roth T, Podestá F, Stepp MA, Boeri D, Lorenzi M (1993). Integrin overexpression induced by high glucose and by human diabetes: potential pathway to cell dysfunction in diabetic microangiopathy. Proc Natl Acad Sci USA 90, 9640-9644. (Pubitemid 23315841)
49. Sechler JL, Corbett SA, Schwarzbauer JE (1997). Modulatory roles for integrin activation and the synergy site of fibronectin during matrix assembly. Mol Biol Cell 8, 2563-2573. (Pubitemid 27528222)
50. Sechler JL, Takada Y, Schwarzbauer JE (1996). Altered rate of fibronectin matrix assembly by deletion of the first type III repeats. J Cell Biol 134, 573-583. (Pubitemid 26255270)
51. Shattil SJ, Kim C, Ginsberg MH (2010). The final steps of integrin activation: the end game. Nat Rev Mol Cell Biol 11, 288-300.
52. Shi F, Harman J, Fujiwara K, Sottile J (2010). Collagen I matrix turnover is regulated by fibronectin polymerization. Am J Physiol Cell Physiol 298, C1265-C1275.
53. Singh P, Carraher C, Schwarzbauer JE (2010). Assembly of fibronectin extracellular matrix. Annu Rev Cell Dev Biol 26, 397-419.
54. Sottile J, Hocking DC (2002). Fibronectin polymerization regulates the composition and stability of extracellular matrix fibrils and cell-matrix adhesions. Mol Biol Cell 13, 3546-3559. (Pubitemid 35191374)
55. Sottile J, Shi F, Rublyevska I, Chiang H-Y, Lust J, Chandler J (2007). Fibronectin-dependent collagen I deposition modulates the cell response to fibronectin. Am J Physiol Cell Physiol 293, C1934-C1946. (Pubitemid 350255083)
56. Sumi A, Yamanaka-Hanada N, Bai F, Makino T, Mizukami H, Ono T (2011). Roles of coagulation pathway and factor Xa in the progression of diabetic nephropathy in db/db mice. Biol Pharm Bull 34, 824-830.
57. Tadokoro S, Shattil SJ, Eto K, Tai V, Liddington RC, de Pereda JM, Ginsberg MH, Calderwood DA (2003). Talin binding to integrin beta tails: a final common step in integrin activation. Science 302, 103-106. (Pubitemid 37210697)
58. Taniguchi K et al. (2013). Inhibition of Src kinase blocks high glucose-induced EGFR transactivation and collagen synthesis in mesangial cells and prevents diabetic nephropathy in mice. Diabetes 62, 3874-3886.
59. Velling T, Risteli J, Wennerberg K, Mosher DF, Johansson S (2002). Polymerization of type I and III collagens is dependent on fibronectin and enhanced by integrins alpha 11beta 1 and alpha 2beta 1. J Biol Chem 277, 37377-37381.
60. Weston BS, Wahab NA, Mason RM (2003). CTGF mediates TGF-beta-induced fibronectin matrix deposition by upregulating active alpha5beta1 integrin in human mesangial cells. J Am Soc Nephrol 14, 601-610. (Pubitemid 36246003)
61. Wierzbicka-Patynowski I, Mao Y, Schwarzbauer JE (2007). Continuous requirement for pp60-Src and phospho-paxillin during fibronectin matrix assembly by transformed cells. J Cell Physiol 210, 750-756. (Pubitemid 46185044)
62. Wilson CL, Schwarzbauer JE (1992). The alternatively spliced V region contributes to the differential incorporation of plasma and cellular fibronectins into fibrin clots. J Cell Biol 119, 923-933.
63. Yamashita S, Mochizuki N, Ohba Y, Tobiume M, Okada Y, Sawa H, Nagashima K, Matsuda M (2000). CalDAG-GEFIII activation of Ras, R-ras, and Rap1. J Biol Chem 275, 25488-25493.
64. Yang J, Zeng Z, Wu T, Yang Z, Liu B, Lan T (2013). Emodin attenuates high glucose-induced TGF-β1 and fibronectin expression in mesangial cells through inhibition of NF-κB pathway. Exp Cell Res 319, 3182-3189.
65. Zent R et al. (2006). Glomerular injury is exacerbated in diabetic integrin alpha1-null mice. Kidney Int 70, 460-470. (Pubitemid 44141572)
66. Zhou XJ, Rakheja D, Yu X, Saxena R, Vaziri ND, Silva FG (2008). The aging kidney. Kidney Int 74, 710-720.