메뉴 건너뛰기




Volumn 22, Issue 1, 2011, Pages 90-103

Blockade of Wnt/β-catenin signaling by paricalcitol ameliorates proteinuria and kidney injury

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; COLLAGEN TYPE 1; COLLAGEN TYPE 3; CONNECTIVE TISSUE GROWTH FACTOR; CYTOKINE; DOXORUBICIN; FIBRONECTIN; NEPHRIN; PARICALCITOL; PODOCIN; TRANSCRIPTION FACTOR SNAIL; TRANSFORMING GROWTH FACTOR BETA1; VITAMIN D RECEPTOR; WNT PROTEIN; WNT10A PROTEIN; WNT4 PROTEIN; WNT7A PROTEIN; WNT7B PROTEIN; WT1 PROTEIN;

EID: 78651384347     PISSN: 10466673     EISSN: 15333450     Source Type: Journal    
DOI: 10.1681/ASN.2009121236     Document Type: Article
Times cited : (247)

References (56)
  • 1
    • 33745058119 scopus 로고    scopus 로고
    • The podocyte's response to injury: Role in proteinuria and glomerulosclerosis
    • Shankland SJ: The podocyte's response to injury: Role in proteinuria and glomerulosclerosis. Kidney Int 69: 2131-2147, 2006
    • (2006) Kidney Int , vol.69 , pp. 2131-2147
    • Shankland, S.J.1
  • 2
    • 34250006557 scopus 로고    scopus 로고
    • The spectrum of podocytopathies: A unifying view of glomerular diseases
    • Wiggins RC: The spectrum of podocytopathies: A unifying view of glomerular diseases. Kidney Int 71: 1205-1214, 2007
    • (2007) Kidney Int , vol.71 , pp. 1205-1214
    • Wiggins, R.C.1
  • 3
    • 70349330816 scopus 로고    scopus 로고
    • New insights into the role of podocytes in proteinuria
    • Patrakka J, Tryggvason K: New insights into the role of podocytes in proteinuria. Nat Rev Nephrol 5: 463-468, 2009
    • (2009) Nat Rev Nephrol , vol.5 , pp. 463-468
    • Patrakka, J.1    Tryggvason, K.2
  • 4
    • 33750736645 scopus 로고    scopus 로고
    • How does proteinuria cause progressive renal damage?
    • Abbate M, Zoja C, Remuzzi G: How does proteinuria cause progressive renal damage? J Am Soc Nephrol 17: 2974-2984, 2006
    • (2006) J Am Soc Nephrol , vol.17 , pp. 2974-2984
    • Abbate, M.1    Zoja, C.2    Remuzzi, G.3
  • 7
    • 65249134946 scopus 로고    scopus 로고
    • Wnt/β-catenin signaling promotes renal interstitial fibrosis
    • He W, Dai C, Li Y, Zeng G, Monga SP, Liu Y: Wnt/β-catenin signaling promotes renal interstitial fibrosis. J Am Soc Nephrol 20: 765-776, 2009
    • (2009) J Am Soc Nephrol , vol.20 , pp. 765-776
    • He, W.1    Dai, C.2    Li, Y.3    Zeng, G.4    Monga, S.P.5    Liu, Y.6
  • 8
    • 53049088426 scopus 로고    scopus 로고
    • WNT/beta-catenin signaling in nephron progenitors and their epithelial progeny
    • Schmidt-Ott KM, Barasch J: WNT/beta-catenin signaling in nephron progenitors and their epithelial progeny. Kidney Int 74: 1004-1008, 2008
    • (2008) Kidney Int , vol.74 , pp. 1004-1008
    • Schmidt-Ott, K.M.1    Barasch, J.2
  • 10
    • 28444468088 scopus 로고    scopus 로고
    • Wnt-dependent beta-catenin signaling is activated after unilateral ureteral obstruction, and recombinant secreted frizzled-related protein 4 alters the progression of renal fibrosis
    • Surendran K, Schiavi S, Hruska KA: Wnt-dependent beta-catenin signaling is activated after unilateral ureteral obstruction, and recombinant secreted frizzled-related protein 4 alters the progression of renal fibrosis. J Am Soc Nephrol 16: 2373-2384, 2005
    • (2005) J Am Soc Nephrol , vol.16 , pp. 2373-2384
    • Surendran, K.1    Schiavi, S.2    Hruska, K.A.3
  • 13
    • 67649470380 scopus 로고    scopus 로고
    • Proximal events in Wnt signal transduction
    • Angers S, Moon RT: Proximal events in Wnt signal transduction. Nat Rev Mol Cell Biol 10: 468-477, 2009
    • (2009) Nat Rev Mol Cell Biol , vol.10 , pp. 468-477
    • Angers, S.1    Moon, R.T.2
  • 15
    • 55749104413 scopus 로고    scopus 로고
    • Vitamin D and Wnt/β-catenin pathway in colon cancer: Role and regulation of DICKKOPF genes
    • Pendas-Franco N, Aguilera O, Pereira F, Gonzalez-Sancho JM, Munoz A: Vitamin D and Wnt/β-catenin pathway in colon cancer: Role and regulation of DICKKOPF genes. Anticancer Res 28: 2613-2623, 2008
    • (2008) Anticancer Res , vol.28 , pp. 2613-2623
    • Pendas-Franco, N.1    Aguilera, O.2    Pereira, F.3    Gonzalez-Sancho, J.M.4    Munoz, A.5
  • 17
    • 33845700085 scopus 로고    scopus 로고
    • Prevalence of abnormal serum vitamin D, PTH, calcium, and phosphorus in patients with chronic kidney disease: Results of the study to evaluate early kidney disease
    • DOI 10.1038/sj.ki.5002009, PII 5002009
    • Levin A, Bakris GL, Molitch M, Smulders M, Tian J, Williams LA, Andress DL: Prevalence of abnormal serum vitamin D, PTH, calcium, and phosphorus in patients with chronic kidney disease: Results of the study to evaluate early kidney disease. Kidney Int 71: 31-38, 2007 (Pubitemid 44967731)
    • (2007) Kidney International , vol.71 , Issue.1 , pp. 31-38
    • Levin, A.1    Bakris, G.L.2    Molitch, M.3    Smulders, M.4    Tian, J.5    Williams, L.A.6    Andress, D.L.7
  • 18
  • 22
    • 73849129217 scopus 로고    scopus 로고
    • Possible renoprotection by vitamin D in chronic renal disease: Beyond mineral metabolism
    • Doorenbos CR, van den Born J, Navis G, de Borst MH: Possible renoprotection by vitamin D in chronic renal disease: beyond mineral metabolism. Nat Rev Nephrol 5: 691-700, 2009
    • (2009) Nat Rev Nephrol , vol.5 , pp. 691-700
    • Doorenbos, C.R.1    Van Den Born, J.2    Navis, G.3    De Borst, M.H.4
  • 24
    • 70349251198 scopus 로고    scopus 로고
    • Oral paricalcitol in the treatment of patients with CKD and proteinuria: A randomized trial
    • Fishbane S, Chittineni H, Packman M, Dutka P, Ali N, Durie N: Oral paricalcitol in the treatment of patients with CKD and proteinuria: A randomized trial. Am J Kidney Dis 54: 647-652, 2009
    • (2009) Am J Kidney Dis , vol.54 , pp. 647-652
    • Fishbane, S.1    Chittineni, H.2    Packman, M.3    Dutka, P.4    Ali, N.5    Durie, N.6
  • 25
    • 0033802098 scopus 로고    scopus 로고
    • Progressive adriamycin nephropathy in mice: Sequence of histologic and immunohistochemical events
    • Wang Y, Wang YP, Tay YC, Harris DC: Progressive adriamycin nephropathy in mice: Sequence of histologic and immunohistochemical events. Kidney Int 58: 1797-1804, 2000
    • (2000) Kidney Int , vol.58 , pp. 1797-1804
    • Wang, Y.1    Wang, Y.P.2    Tay, Y.C.3    Harris, D.C.4
  • 27
    • 0037087593 scopus 로고    scopus 로고
    • WT1 is a key regulator of podocyte function: Reduced expression levels cause crescentic glomerulonephritis and mesangial sclerosis
    • Guo JK, Menke AL, Gubler MC, Clarke AR, Harrison D, Hammes A, Hastie ND, Schedl A: WT1 is a key regulator of podocyte function: Reduced expression levels cause crescentic glomerulonephritis and mesangial sclerosis. Hum Mol Genet 11: 651-659, 2002
    • (2002) Hum Mol Genet , vol.11 , pp. 651-659
    • Guo, J.K.1    Menke, A.L.2    Gubler, M.C.3    Clarke, A.R.4    Harrison, D.5    Hammes, A.6    Hastie, N.D.7    Schedl, A.8
  • 29
    • 77955877135 scopus 로고    scopus 로고
    • Hepatocyte growth factor signaling ameliorates podocyte injury and proteinuria
    • Dai C, Saleem MA, Holzman LB, Mathieson P, Liu Y: Hepatocyte growth factor signaling ameliorates podocyte injury and proteinuria. Kidney Int 77: 962-973, 2010
    • (2010) Kidney Int , vol.77 , pp. 962-973
    • Dai, C.1    Saleem, M.A.2    Holzman, L.B.3    Mathieson, P.4    Liu, Y.5
  • 30
    • 73249129568 scopus 로고    scopus 로고
    • Vitamin D, proteinuria, diabetic nephropathy, and progression of CKD
    • Agarwal R: Vitamin D, proteinuria, diabetic nephropathy, and progression of CKD. Clin J Am Soc Nephrol 4: 1523-1528, 2009
    • (2009) Clin J Am Soc Nephrol , vol.4 , pp. 1523-1528
    • Agarwal, R.1
  • 31
    • 67650757568 scopus 로고    scopus 로고
    • Podocyte injury is suppressed by 1,25-dihydroxyvitamin D via modulation of transforming growth factor-beta1/bone morphogenetic protein-7 signalling in puromycin aminonucleoside nephropathy rats
    • Xiao HQ, Shi W, Liu SX, Zhang B, Xu LX, Liang XL, Liang YZ: Podocyte injury is suppressed by 1,25-dihydroxyvitamin D via modulation of transforming growth factor-beta1/bone morphogenetic protein-7 signalling in puromycin aminonucleoside nephropathy rats. Clin Exp Pharmacol Physiol 36: 682-689, 2009
    • (2009) Clin Exp Pharmacol Physiol , vol.36 , pp. 682-689
    • Xiao, H.Q.1    Shi, W.2    Liu, S.X.3    Zhang, B.4    Xu, L.X.5    Liang, X.L.6    Liang, Y.Z.7
  • 33
    • 57349185929 scopus 로고    scopus 로고
    • Combination therapy with AT1 blocker and vitamin D analog markedly ameliorates diabetic nephropathy: Blockade of compensatory renin increase
    • Zhang Z, Zhang Y, Ning G, Deb DK, Kong J, Li YC: Combination therapy with AT1 blocker and vitamin D analog markedly ameliorates diabetic nephropathy: Blockade of compensatory renin increase. Proc Natl Acad Sci U S A 105: 15896-15901, 2008
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 15896-15901
    • Zhang, Z.1    Zhang, Y.2    Ning, G.3    Deb, D.K.4    Kong, J.5    Li, Y.C.6
  • 34
    • 34249868434 scopus 로고    scopus 로고
    • Combination therapy with an angiotensin-converting enzyme inhibitor and A vitamin D analog suppresses the progression of renal insufficiency in uremic rats
    • Mizobuchi M, Morrissey J, Finch JL, Martin DR, Liapis H, Akizawa T, Slatopolsky E: Combination therapy with an angiotensin-converting enzyme inhibitor and a vitamin D analog suppresses the progression of renal insufficiency in uremic rats. J Am Soc Nephrol 18: 1796-1806, 2007
    • (2007) J Am Soc Nephrol , vol.18 , pp. 1796-1806
    • Mizobuchi, M.1    Morrissey, J.2    Finch, J.L.3    Martin, D.R.4    Liapis, H.5    Akizawa, T.6    Slatopolsky, E.7
  • 38
    • 33847671000 scopus 로고    scopus 로고
    • Snail, a transcriptional regulator, represses nephrin expression in glomerular epithelial cells of nephrotic rats
    • DOI 10.1038/labinvest.3700518, PII 3700518
    • Matsui I, Ito T, Kurihara H, Imai E, Ogihara T, Hori M: Snail, a transcriptional regulator, represses nephrin expression in glomerular epithelial cells of nephrotic rats. Lab Invest 87: 273-283, 2007 (Pubitemid 46353945)
    • (2007) Laboratory Investigation , vol.87 , Issue.3 , pp. 273-283
    • Matsui, I.1    Ito, T.2    Kurihara, H.3    Imai, E.4    Ogihara, T.5    Hori, M.6
  • 39
    • 77949351029 scopus 로고    scopus 로고
    • New insights into epithelial-mesenchymal transition in kidney fibrosis
    • Liu Y: New insights into epithelial-mesenchymal transition in kidney fibrosis. J Am Soc Nephrol 21: 212-222, 2010
    • (2010) J Am Soc Nephrol , vol.21 , pp. 212-222
    • Liu, Y.1
  • 40
    • 77955172248 scopus 로고    scopus 로고
    • Inhibition of integrin-linked kinase blocks podocyte epithelial- mesenchymal transition and ameliorates proteinuria
    • Kang YS, Li Y, Dai C, Kiss LP, Wu C, Liu Y: Inhibition of integrin-linked kinase blocks podocyte epithelial-mesenchymal transition and ameliorates proteinuria. Kidney Int 78: 363-373, 2010
    • (2010) Kidney Int , vol.78 , pp. 363-373
    • Kang, Y.S.1    Li, Y.2    Dai, C.3    Kiss, L.P.4    Wu, C.5    Liu, Y.6
  • 41
    • 39549098861 scopus 로고    scopus 로고
    • Epithelial-to-mesenchymal transition is a potential pathway leading to podocyte dysfunction and proteinuria
    • DOI 10.2353/ajpath.2008.070057
    • Li Y, Kang YS, Dai C, Kiss LP, Wen X, Liu Y: Epithelial-to-mesenchymal transition is a potential pathway leading to podocyte dysfunction and proteinuria. Am J Pathol 172: 299-308, 2008 (Pubitemid 351282018)
    • (2008) American Journal of Pathology , vol.172 , Issue.2 , pp. 299-308
    • Li, Y.1    Kang, Y.S.2    Dai, C.3    Kiss, L.P.4    Wen, X.5    Liu, Y.6
  • 43
    • 33845242306 scopus 로고    scopus 로고
    • Paricalcitol attenuates renal interstitial fibrosis in obstructive nephropathy
    • DOI 10.1681/ASN.2006050520
    • Tan X, Li Y, Liu Y: Paricalcitol attenuates renal interstitial fibrosis in obstructive nephropathy. J Am Soc Nephrol 17: 3382-3393, 2006 (Pubitemid 44865281)
    • (2006) Journal of the American Society of Nephrology , vol.17 , Issue.12 , pp. 3382-3393
    • Tan, X.1    Li, Y.2    Liu, Y.3
  • 46
    • 33751582928 scopus 로고    scopus 로고
    • Snail activation disrupts tissue homeostasis and induces fibrosis in the adult kidney
    • Boutet A, De Frutos CA, Maxwell PH, Mayol MJ, Romero J, Nieto MA: Snail activation disrupts tissue homeostasis and induces fibrosis in the adult kidney. EMBO J 25: 5603-5613, 2006
    • (2006) EMBO J , vol.25 , pp. 5603-5613
    • Boutet, A.1    De Frutos, C.A.2    Maxwell, P.H.3    Mayol, M.J.4    Romero, J.5    Nieto, M.A.6
  • 48
    • 5444269904 scopus 로고    scopus 로고
    • Dual regulation of Snail by GSK-3beta-mediated phosphorylation in control of epithelial-mesenchymal transition
    • Zhou BP, Deng J, Xia W, Xu J, Li YM, Gunduz M, Hung MC: Dual regulation of Snail by GSK-3beta-mediated phosphorylation in control of epithelial-mesenchymal transition. Nat Cell Biol 6: 931-940, 2004
    • (2004) Nat Cell Biol , vol.6 , pp. 931-940
    • Zhou, B.P.1    Deng, J.2    Xia, W.3    Xu, J.4    Li, Y.M.5    Gunduz, M.6    Hung, M.C.7
  • 49
    • 54749105918 scopus 로고    scopus 로고
    • Paricalcitol inhibits renal inflammation by promoting svitamin D receptor-mediated sequestration of NF-κB signaling
    • Tan X, Wen X, Liu Y: Paricalcitol inhibits renal inflammation by promoting svitamin D receptor-mediated sequestration of NF-κB signaling. J Am Soc Nephrol 19: 1741-1752, 2008
    • (2008) J Am Soc Nephrol , vol.19 , pp. 1741-1752
    • Tan, X.1    Wen, X.2    Liu, Y.3
  • 50
    • 65349092794 scopus 로고    scopus 로고
    • Stabilization of snail by NF-kappaB is required for inflammation-induced cell migration and invasion
    • Wu Y, Deng J, Rychahou PG, Qiu S, Evers BM, Zhou BP: Stabilization of snail by NF-kappaB is required for inflammation-induced cell migration and invasion. Cancer Cell 15: 416-428, 2009
    • (2009) Cancer Cell , vol.15 , pp. 416-428
    • Wu, Y.1    Deng, J.2    Rychahou, P.G.3    Qiu, S.4    Evers, B.M.5    Zhou, B.P.6
  • 52
    • 33746491157 scopus 로고    scopus 로고
    • Essential role of integrin-linked kinase in podocyte biology: Bridging the integrin and slit diaphragm signaling
    • Dai C, Stolz DB, Bastacky SI, St-Arnaud R, Wu C, Dedhar S, Liu Y: Essential role of integrin-linked kinase in podocyte biology: Bridging the integrin and slit diaphragm signaling. J Am Soc Nephrol 17: 2164-2175, 2006
    • (2006) J Am Soc Nephrol , vol.17 , pp. 2164-2175
    • Dai, C.1    Stolz, D.B.2    Bastacky, S.I.3    St-Arnaud, R.4    Wu, C.5    Dedhar, S.6    Liu, Y.7
  • 53
    • 0029824210 scopus 로고    scopus 로고
    • Primary structure of rat HGF receptor and induced expression in glomerular mesangial cells
    • Liu Y, Tolbert EM, Sun AM, Dworkin LD: Primary structure of rat HGF receptor and induced expression in glomerular mesangial cells. Am J Physiol 271: F679-F688, 1996
    • (1996) Am J Physiol , vol.271
    • Liu, Y.1    Tolbert, E.M.2    Sun, A.M.3    Dworkin, L.D.4
  • 54
    • 69849100333 scopus 로고    scopus 로고
    • Inhibition of integrin-linked kinase attenuates renal interstitial fibrosis
    • Li Y, Tan X, Dai C, Stolz DB, Wang D, Liu Y: Inhibition of integrin-linked kinase attenuates renal interstitial fibrosis. J Am Soc Nephrol 20: 1907-1918, 2009
    • (2009) J Am Soc Nephrol , vol.20 , pp. 1907-1918
    • Li, Y.1    Tan, X.2    Dai, C.3    Stolz, D.B.4    Wang, D.5    Liu, Y.6
  • 55
    • 0031563832 scopus 로고    scopus 로고
    • Rearrangements of the cytoskeleton and cell contacts induce process formation during differentiation of conditionally immortalized mouse podocyte cell lines
    • DOI 10.1006/excr.1997.3739
    • Mundel P, Reiser J, Zuniga Mejia Borja A, Pavenstadt H, Davidson GR, Kriz W, Zeller R: Rearrangements of the cytoskeleton and cell contacts induce process formation during differentiation of conditionally immortalized mouse podocyte cell lines. Exp Cell Res 236: 248-258, 1997 (Pubitemid 27452369)
    • (1997) Experimental Cell Research , vol.236 , Issue.1 , pp. 248-258
    • Mundel, P.1    Reiser, J.2    Borja, A.Z.M.3    Pavenstadt, H.4    Davidson, G.R.5    Kriz, W.6    Zeller, R.7
  • 56
    • 0041843962 scopus 로고    scopus 로고
    • Hepatocyte growth factor suppresses renal interstitial myofibroblast activation and intercepts Smad signal transduction
    • Yang J, Dai C, Liu Y: Hepatocyte growth factor suppresses renal interstitial myofibroblast activation and intercepts Smad signal transduction. Am J Pathol 163: 621-632, 2003 (Pubitemid 36909423)
    • (2003) American Journal of Pathology , vol.163 , Issue.2 , pp. 621-632
    • Yang, J.1    Dai, C.2    Liu, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.