The Ras GTPase-activating-like protein IQGAP1 is downregulated in human diabetic nephropathy and associated with ERK1/2 pathway activation

Molecular and Cellular Biochemistry

Volumn 391, Issue 1-2, 2014, Pages 21-25

  Zhou, Hua ^a   Yao, Chunlei ^a   Bian, Ao ^a   Qian, Jun ^a   Zhao, Xiufen ^a   Zhao, Yanting ^a   Wang, Weiwei ^a   Xing, Changying ^a  

^a THE FIRST AFFILIATED HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Diabetic nephropathy; Extracellular signal regulated kinase 1 2; IQGAP1; Podocyte

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; GLUCOSE; IQ MOTIF CONTAINING GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN 1; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; 2-(2-AMINO-3-METHOXYPHENYL)-4H-1-BENZOPYRAN-4-ONE; FLAVONOID; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN;

ARTICLE; CONTROLLED STUDY; DIABETIC NEPHROPATHY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; KIDNEY BIOPSY; NON INSULIN DEPENDENT DIABETES MELLITUS; PODOCYTE; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; BIOPSY; CELL CULTURE; DRUG EFFECTS; ENZYMOLOGY; GENETICS; GLOMERULUS; METABOLISM; PATHOLOGY;

BIOPSY; CELLS, CULTURED; DIABETIC NEPHROPATHIES; DOWN-REGULATION; ENZYME ACTIVATION; FLAVONOIDS; GLUCOSE; HUMANS; KIDNEY GLOMERULUS; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; PODOCYTES; RAS GTPASE-ACTIVATING PROTEINS; RNA, MESSENGER;

EID: 84900801528     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-014-1982-x     Document Type: Article

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