MicroRNAs as key regulators of xenobiotic biotransformation and drug response

Archives of Toxicology

Volumn 89, Issue 9, 2015, Pages 1523-1541

  Bolleyn, Jennifer ^a   De Kock, Joery ^a   Rodrigues, Robim Marcelino ^a   Vinken, Mathieu ^a   Rogiers, Vera ^a   Vanhaecke, Tamara ^a  

^a VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

Author keywords

Cytochrome P450 enzymes; Drug metabolism; Drug transporters; MicroRNA; Transcription factors

Indexed keywords

CYTOCHROME P450 1A1; CYTOCHROME P450 1B1; CYTOCHROME P450 2A6; CYTOCHROME P450 2B6; CYTOCHROME P450 2C8; CYTOCHROME P450 2C9; MICRORNA; MICRORNA 1; MICRORNA 101; MICRORNA 122; MICRORNA 125B; MICRORNA 126; MICRORNA 132; MICRORNA 143; MICRORNA 146A; MICRORNA 15A; MICRORNA 16; MICRORNA 200A; MICRORNA 200B; MICRORNA 20B; MICRORNA 21; MICRORNA 214; MICRORNA 22; MICRORNA 221; MICRORNA 223; MICRORNA 24; MICRORNA 29A; MICRORNA 31; MICRORNA 9; XENOBIOTIC AGENT; CELL RECEPTOR; DRUG; MESSENGER RNA; TRANSCRIPTION FACTOR;

APOPTOSIS; BIOGENESIS; CELL CYCLE ARREST; DEVELOPMENT; DNA DAMAGE; DNA METHYLATION; DRUG RESPONSE; DRUG TRANSFORMATION; DRUG TRANSPORT; EPIGENETICS; GENE EXPRESSION; HISTONE MODIFICATION; HUMAN; LIVER CELL CARCINOMA; LIVER POLYCYSTIC DISEASE; NONALCOHOLIC FATTY LIVER; PRIORITY JOURNAL; REVIEW; SINGLE NUCLEOTIDE POLYMORPHISM; TRANSCRIPTION REGULATION; VIRUS HEPATITIS; ADVERSE DRUG REACTION; ANIMAL; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; LIVER; METABOLISM;

ANIMALS; DRUG-RELATED SIDE EFFECTS AND ADVERSE REACTIONS; GENE EXPRESSION REGULATION; HUMANS; LIVER; MICRORNAS; PHARMACEUTICAL PREPARATIONS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RNA, MESSENGER; TRANSCRIPTION FACTORS; XENOBIOTICS;

EID: 84940579824     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-014-1314-7     Document Type: Review

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