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Volumn 40, Issue 4, 2012, Pages 726-733

In silico and in vitro identification of microRNAs that regulate hepatic nuclear factor 4α expression

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 2D6; HEPATOCYTE NUCLEAR FACTOR 4ALPHA; MICRORNA; PURINERGIC RECEPTOR;

EID: 84863391693     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.111.040329     Document Type: Article
Times cited : (69)

References (40)
  • 1
    • 34250843675 scopus 로고    scopus 로고
    • The micro-ribonucleic acid (miRNA) miR-206 targets the human estrogen receptor-α (ERα) and represses ERα messenger RNA and protein expression in breast cancer cell lines
    • DOI 10.1210/me.2007-0022
    • Adams BD, Furneaux H, and White BA (2007) The micro-ribonucleic acid (miRNA) miR-206 targets the human estrogen receptor-α (ERα) and represses ERα messenger RNA and protein expression in breast cancer cell lines. Mol Endocrinol 21:1132-1147. (Pubitemid 46984764)
    • (2007) Molecular Endocrinology , vol.21 , Issue.5 , pp. 1132-1147
    • Adams, B.D.1    Furneaux, H.2    White, B.A.3
  • 3
    • 33846118697 scopus 로고    scopus 로고
    • PolymiRTS Database: Linking polymorphisms in microRNA target sites with complex traits
    • DOI 10.1093/nar/gkl797
    • Bao L, Zhou M, Wu L, Lu L, Goldowitz D, Williams RW, and Cui Y (2007) PolymiRTS Database: linking polymorphisms in microRNA target sites with complex traits. Nucleic Acids Res 35:D51-D54. (Pubitemid 46056169)
    • (2007) Nucleic Acids Research , vol.35 , Issue.SUPPL. 1
    • Bao, L.1    Zhou, M.2    Wu, L.3    Lu, L.4    Goldowitz, D.5    Williams, R.W.6    Cui, Y.7
  • 4
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: Genomics, biogenesis, mechanism, and function
    • Bartel DP (2004) MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116:281-297.
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 5
    • 77956255908 scopus 로고    scopus 로고
    • Composite functional genetic and comedication CYP2D6 activity score in predicting tamoxifen drug exposure among breast cancer patients
    • Borges S, Desta Z, Jin Y, Faouzi A, Robarge JD, Philips S, Philip S, Nguyen A, Stearns V, Hayes D, et al. (2010) Composite functional genetic and comedication CYP2D6 activity score in predicting tamoxifen drug exposure among breast cancer patients. J Clin Pharmacol 50:450-458.
    • (2010) J Clin Pharmacol , vol.50 , pp. 450-458
    • Borges, S.1    Desta, Z.2    Jin, Y.3    Faouzi, A.4    Robarge, J.D.5    Philips, S.6    Philip, S.7    Nguyen, A.8    Stearns, V.9    Hayes, D.10
  • 7
    • 42449086421 scopus 로고    scopus 로고
    • miR-148 targets human DNMT3b protein coding region
    • DOI 10.1261/rna.972008
    • Duursma AM, Kedde M, Schrier M, le Sage C, and Agami R (2008) miR-148 targets human DNMT3b protein coding region. RNA 14:872-877. (Pubitemid 351574909)
    • (2008) RNA , vol.14 , Issue.5 , pp. 872-877
    • Duursma, A.M.1    Kedde, M.2    Schrier, M.3    Le, S.C.4    Agami, R.5
  • 12
    • 48249132875 scopus 로고    scopus 로고
    • The diabetic phenotype in HNF4A mutation carriers is moderated by the expression of HNF4A isoforms from the P1 promoter during fetal development
    • Harries LW, Locke JM, Shields B, Hanley NA, Hanley KP, Steele A, Njølstad PR, Ellard S, and Hattersley AT (2008) The diabetic phenotype in HNF4A mutation carriers is moderated by the expression of HNF4A isoforms from the P1 promoter during fetal development. Diabetes 57:1745-1752.
    • (2008) Diabetes , vol.57 , pp. 1745-1752
    • Harries, L.W.1    Locke, J.M.2    Shields, B.3    Hanley, N.A.4    Hanley, K.P.5    Steele, A.6    Njølstad, P.R.7    Ellard, S.8    Hattersley, A.T.9
  • 13
    • 0034796563 scopus 로고    scopus 로고
    • Regulatory mechanisms controlling human hepatocyte nuclear factor 4α gene expression
    • DOI 10.1128/MCB.21.21.7320-7330.2001
    • Hatzis P and Talianidis I (2001) Regulatory mechanisms controlling human hepatocyte nuclear factor 4α gene expression. Mol Cell Biol 21:7320-7330. (Pubitemid 32953485)
    • (2001) Molecular and Cellular Biology , vol.21 , Issue.21 , pp. 7320-7330
    • Hatzis, P.1    Talianidis, I.2
  • 14
    • 0035141324 scopus 로고    scopus 로고
    • Hepatocyte nuclear factor 4α (Nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis
    • DOI 10.1128/MCB.21.4.1393-1403.2001
    • Hayhurst GP, Lee YH, Lambert G, Ward JM, and Gonzalez FJ (2001) Hepatocyte nuclear factor 4α (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis. Mol Cell Biol 21:1393-1403. (Pubitemid 32114986)
    • (2001) Molecular and Cellular Biology , vol.21 , Issue.4 , pp. 1393-1403
    • Hayhurst, G.P.1    Lee, Y.-H.2    Lambert, G.3    Ward, J.M.4    Gonzalez, F.J.5
  • 16
    • 36148976077 scopus 로고    scopus 로고
    • Influence of cytochrome P450 polymorphisms on drug therapies: Pharmacogenetic, pharmacoepigenetic and clinical aspects
    • DOI 10.1016/j.pharmthera.2007.09.004, PII S016372580700201X
    • Ingelman-Sundberg M, Sim SC, Gomez A, and Rodriguez-Antona C (2007) Influence of cytochrome P450 polymorphisms on drug therapies: pharmacogenetic, pharmacoepigenetic and clinical aspects. Pharmacol Ther 116:496-526. (Pubitemid 350116943)
    • (2007) Pharmacology and Therapeutics , vol.116 , Issue.3 , pp. 496-526
    • Ingelman-Sundberg, M.1    Sim, S.C.2    Gomez, A.3    Rodriguez-Antona, C.4
  • 17
    • 42249098584 scopus 로고    scopus 로고
    • Involvement of hepatocyte nuclear factor 4α in transcriptional regulation of the human pregnane X receptor gene in the human liver
    • Iwazaki N, Kobayashi K, Morimoto K, Hirano M, Kawashima S, Furihata T, and Chiba K (2008) Involvement of hepatocyte nuclear factor 4α in transcriptional regulation of the human pregnane X receptor gene in the human liver. Drug Metab Pharmacokinet 23:59-66.
    • (2008) Drug Metab Pharmacokinet , vol.23 , pp. 59-66
    • Iwazaki, N.1    Kobayashi, K.2    Morimoto, K.3    Hirano, M.4    Kawashima, S.5    Furihata, T.6    Chiba, K.7
  • 19
    • 34848824067 scopus 로고    scopus 로고
    • Role of human hepatocyte nuclear factor 4α in the expression of drug-metabolizing enzymes and transporters in human hepatocytes assessed by use of small interfering RNA
    • Kamiyama Y, Matsubara T, Yoshinari K, Nagata K, Kamimura H, and Yamazoe Y (2007) Role of human hepatocyte nuclear factor 4α in the expression of drug-metabolizing enzymes and transporters in human hepatocytes assessed by use of small interfering RNA. Drug Metab Pharmacokinet 22:287-298.
    • (2007) Drug Metab Pharmacokinet , vol.22 , pp. 287-298
    • Kamiyama, Y.1    Matsubara, T.2    Yoshinari, K.3    Nagata, K.4    Kamimura, H.5    Yamazoe, Y.6
  • 20
    • 34748821761 scopus 로고    scopus 로고
    • The role of site accessibility in microRNA target recognition
    • DOI 10.1038/ng2135, PII NG2135
    • Kertesz M, Iovino N, Unnerstall U, Gaul U, and Segal E (2007) The role of site accessibility in microRNA target recognition. Nat Genet 39:1278-1284. (Pubitemid 47482690)
    • (2007) Nature Genetics , vol.39 , Issue.10 , pp. 1278-1284
    • Kertesz, M.1    Iovino, N.2    Unnerstall, U.3    Gaul, U.4    Segal, E.5
  • 22
    • 0033168968 scopus 로고    scopus 로고
    • Lightcycler technology for the quantitation of bcr/abl fusion transcripts
    • Kreuzer KA, Lass U, Bohn A, Landt O, and Schmidt CA (1999) LightCycler technology for the quantitation of bcr/abl fusion transcripts. Cancer Res 59:3171-3174. (Pubitemid 29316018)
    • (1999) Cancer Research , vol.59 , Issue.13 , pp. 3171-3174
    • Kreuzer, K.-A.1    Lass, U.2    Bohn, A.3    Landt, O.4    Schmidt, C.A.5
  • 23
    • 11844278458 scopus 로고    scopus 로고
    • Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
    • DOI 10.1016/j.cell.2004.12.035, PII S0092867404012607
    • Lewis BP, Burge CB, and Bartel DP (2005) Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 120:15-20. (Pubitemid 40094598)
    • (2005) Cell , vol.120 , Issue.1 , pp. 15-20
    • Lewis, B.P.1    Burge, C.B.2    Bartel, D.P.3
  • 24
    • 0346094457 scopus 로고    scopus 로고
    • Prediction of Mammalian MicroRNA Targets
    • DOI 10.1016/S0092-8674(03)01018-3
    • Lewis BP, Shih IH, Jones-Rhoades MW, Bartel DP, and Burge CB (2003) Prediction of mammalian microRNA targets. Cell 115:787-798. (Pubitemid 38058492)
    • (2003) Cell , vol.115 , Issue.7 , pp. 787-798
    • Lewis, B.P.1    Shih, I.-H.2    Jones-Rhoades, M.W.3    Bartel, D.P.4    Burge, C.B.5
  • 25
    • 33748587841 scopus 로고    scopus 로고
    • A Pattern-Based Method for the Identification of MicroRNA Binding Sites and Their Corresponding Heteroduplexes
    • DOI 10.1016/j.cell.2006.07.031, PII S0092867406010993
    • Miranda KC, Huynh T, Tay Y, Ang YS, Tam WL, Thomson AM, Lim B, and Rigoutsos I (2006) A pattern-based method for the identification of microRNA binding sites and their corresponding heteroduplexes. Cell 126:1203-1217. (Pubitemid 44380294)
    • (2006) Cell , vol.126 , Issue.6 , pp. 1203-1217
    • Miranda, K.C.1    Huynh, T.2    Tay, Y.3    Ang, Y.-S.4    Tam, W.-L.5    Thomson, A.M.6    Lim, B.7    Rigoutsos, I.8
  • 27
    • 0033572284 scopus 로고    scopus 로고
    • The lin-4 regulatory RNA controls developmental timing in Caenorhabditis elegans by blocking LIN-14 protein synthesis after the initiation of translation
    • DOI 10.1006/dbio.1999.9523
    • Olsen PH and Ambros V (1999) The lin-4 regulatory RNA controls developmental timing in Caenorhabditis elegans by blocking LIN-14 protein synthesis after the initiation of translation. Dev Biol 216:671-680. (Pubitemid 30013313)
    • (1999) Developmental Biology , vol.216 , Issue.2 , pp. 671-680
    • Olsen, P.H.1    Ambros, V.2
  • 28
    • 43449090367 scopus 로고    scopus 로고
    • MicroRNA-10a Binds the 5′UTR of Ribosomal Protein mRNAs and Enhances Their Translation
    • DOI 10.1016/j.molcel.2008.05.001, PII S1097276508003286
    • Ørom UA, Nielsen FC, and Lund AH (2008) MicroRNA-10a binds the 5′UTR of ribosomal protein mRNAs and enhances their translation. Mol Cell 30:460-471. (Pubitemid 351672378)
    • (2008) Molecular Cell , vol.30 , Issue.4 , pp. 460-471
    • Orom, U.A.1    Nielsen, F.C.2    Lund, A.H.3
  • 29
    • 70349268327 scopus 로고    scopus 로고
    • MicroRNAs regulate CYP3A4 expression via direct and indirect targeting
    • Pan YZ, Gao W, and Yu AM (2009) MicroRNAs regulate CYP3A4 expression via direct and indirect targeting. Drug Metab Dispos 37:2112-2117.
    • (2009) Drug Metab Dispos , vol.37 , pp. 2112-2117
    • Pan, Y.Z.1    Gao, W.2    Yu, A.M.3
  • 31
    • 79954537612 scopus 로고    scopus 로고
    • In silico identification of microRNAs predicted to regulate the drug metabolizing cytochrome P450 genes
    • Ramamoorthy A and Skaar TC (2011) In silico identification of microRNAs predicted to regulate the drug metabolizing cytochrome P450 genes. Drug Metabolism Letters 5:126-131.
    • (2011) Drug Metabolism Letters , vol.5 , pp. 126-131
    • Ramamoorthy, A.1    Skaar, T.C.2
  • 32
    • 0030695445 scopus 로고    scopus 로고
    • The maturity-onset diabetes of the young (MODY1) transcription factor HNF4α regulates expression of genes required for glucose transport and metabolism
    • DOI 10.1073/pnas.94.24.13209
    • Stoffel M and Duncan SA (1997) The maturity-onset diabetes of the young (MODY1) transcription factor HNF4α regulates expression of genes required for glucose transport and metabolism. Proc Natl Acad Sci USA 94:13209-13214. (Pubitemid 27518501)
    • (1997) Proceedings of the National Academy of Sciences of the United States of America , vol.94 , Issue.24 , pp. 13209-13214
    • Stoffel, M.1    Duncan, S.A.2
  • 33
    • 77951157723 scopus 로고    scopus 로고
    • MicroRNAs regulate human hepatocyte nuclear factor 4α, modulating the expression of metabolic enzymes and cell cycle
    • Takagi S, Nakajima M, Kida K, Yamaura Y, Fukami T, and Yokoi T (2010) MicroRNAs regulate human hepatocyte nuclear factor 4α, modulating the expression of metabolic enzymes and cell cycle. J Biol Chem 285:4415-4422.
    • (2010) J Biol Chem , vol.285 , pp. 4415-4422
    • Takagi, S.1    Nakajima, M.2    Kida, K.3    Yamaura, Y.4    Fukami, T.5    Yokoi, T.6
  • 34
    • 44349182094 scopus 로고    scopus 로고
    • Post-transcriptional regulation of human pregnane X receptor by micro-RNA affects the expression of cytochrome P450 3A4
    • Takagi S, Nakajima M, Mohri T, and Yokoi T (2008) Post-transcriptional regulation of human pregnane X receptor by micro-RNA affects the expression of cytochrome P450 3A4. J Biol Chem 283:9674-9680.
    • (2008) J Biol Chem , vol.283 , pp. 9674-9680
    • Takagi, S.1    Nakajima, M.2    Mohri, T.3    Yokoi, T.4
  • 35
    • 50249188925 scopus 로고    scopus 로고
    • Regulation of ABCG2 expression at the 3′untranslated region of its mRNA through modulation of transcript stability and protein translation by a putative microRNA in the S1 colon cancer cell line
    • To KK, Zhan Z, Litman T, and Bates SE (2008) Regulation of ABCG2 expression at the 3′untranslated region of its mRNA through modulation of transcript stability and protein translation by a putative microRNA in the S1 colon cancer cell line. Mol Cell Biol 28:5147-5161.
    • (2008) Mol Cell Biol , vol.28 , pp. 5147-5161
    • To, K.K.1    Zhan, Z.2    Litman, T.3    Bates, S.E.4
  • 36
    • 33749487425 scopus 로고    scopus 로고
    • MicroRNA regulates the expression of human cytochrome P450 1B1
    • DOI 10.1158/0008-5472.CAN-06-1403
    • Tsuchiya Y, Nakajima M, Takagi S, Taniya T, and Yokoi T (2006) MicroRNA regulates the expression of human cytochrome P450 1B1. Cancer Res 66:9090-9098. (Pubitemid 44521128)
    • (2006) Cancer Research , vol.66 , Issue.18 , pp. 9090-9098
    • Tsuchiya, Y.1    Nakajima, M.2    Takagi, S.3    Taniya, T.4    Yokoi, T.5
  • 37
    • 29644437407 scopus 로고    scopus 로고
    • 3′-UTR polymorphism in the human CYP2A6 gene affects mRNA stability and enzyme expression
    • DOI 10.1016/j.bbrc.2005.12.035, PII S0006291X05027968
    • Wang J, Pitarque M, and Ingelman-Sundberg M (2006) 3′-UTR polymorphism in the human CYP2A6 gene affects mRNA stability and enzyme expression. Biochem Biophys Res Commun 340:491-497. (Pubitemid 43021775)
    • (2006) Biochemical and Biophysical Research Communications , vol.340 , Issue.2 , pp. 491-497
    • Wang, J.1    Pitarque, M.2    Ingelman-Sundberg, M.3
  • 38
    • 34548082616 scopus 로고    scopus 로고
    • Expression of constitutive androstane receptor, hepatic nuclear factor 4α, and P450 oxidoreductase genes determines interindividual variability in basal expression and activity of a broad scope of xenobiotic metabolism genes in the human liver
    • DOI 10.1124/dmd.107.016436
    • Wortham M, Czerwinski M, He L, Parkinson A, and Wan YJ (2007) Expression of constitutive androstane receptor, hepatic nuclear factor 4α, and P450 oxidoreductase genes determines interindividual variability in basal expression and activity of a broad scope of xenobiotic metabolism genes in the human liver. Drug Metab Dispos 35:1700-1710. (Pubitemid 47296067)
    • (2007) Drug Metabolism and Disposition , vol.35 , Issue.9 , pp. 1700-1710
    • Wortham, M.1    Czerwinski, M.2    He, L.3    Parkinson, A.4    Wan, Y.-J.Y.5
  • 39
    • 15244358503 scopus 로고    scopus 로고
    • Systematic discovery of regulatory motifs in human promoters and 3′ UTRs by comparison of several mammals
    • DOI 10.1038/nature03441
    • Xie X, Lu J, Kulbokas EJ, Golub TR, Mootha V, Lindblad-Toh K, Lander ES, and Kellis M (2005) Systematic discovery of regulatory motifs in human promoters and 3′ UTRs by comparison of several mammals. Nature 434:338-345. (Pubitemid 40469170)
    • (2005) Nature , vol.434 , Issue.7031 , pp. 338-345
    • Xie, X.1    Lu, J.2    Kulbokas, E.J.3    Golub, T.R.4    Mootha, V.5    Lindblad-Toh, K.6    Lander, E.S.7    Kellis, M.8
  • 40
    • 2142654329 scopus 로고    scopus 로고
    • MicroRNA-Directed Cleavage of HOXB8 mRNA
    • DOI 10.1126/science.1097434
    • Yekta S, Shih IH, and Bartel DP (2004) MicroRNA-directed cleavage of HOXB8 mRNA. Science 304:594-596. (Pubitemid 38541919)
    • (2004) Science , vol.304 , Issue.5670 , pp. 594-596
    • Yekta, S.1    Shih, I.-H.2    Bartel, D.P.3


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