-
1
-
-
0037321349
-
New microRNAs from mouse and human
-
Lagos-Quintana M, Rauhut R, Meyer J, Borkhardt A, Tuschl T. 2003. New microRNAs from mouse and human. RNA 9:175-79
-
(2003)
RNA
, vol.9
, pp. 175-179
-
-
Lagos-Quintana, M.1
Rauhut, R.2
Meyer, J.3
Borkhardt, A.4
Tuschl, T.5
-
4
-
-
33748928159
-
The diverse functions of microRNAs in animal development and disease
-
Kloosterman WP, Plasterk RH. 2006. The diverse functions of microRNAs in animal development and disease. Dev. Cell 11:441-50
-
(2006)
Dev. Cell
, vol.11
, pp. 441-450
-
-
Kloosterman, W.P.1
Plasterk, R.H.2
-
5
-
-
77955902024
-
The widespread regulation of microRNA biogenesis, function and decay
-
Krol J, Loedige I, Filipowicz W. 2010. The widespread regulation of microRNA biogenesis, function and decay. Nat. Rev. Genet. 11:597-610
-
(2010)
Nat. Rev. Genet
, vol.11
, pp. 597-610
-
-
Krol, J.1
Loedige, I.2
Filipowicz, W.3
-
7
-
-
66049133419
-
Mechanism of miRNA-mediated post-transcriptional regulation in animal cells
-
Chekulaeva M, Filipowicz W. 2009. Mechanism of miRNA-mediated post-transcriptional regulation in animal cells. Curr. Opin. Cell Biol. 21:452-60
-
(2009)
Curr. Opin. Cell Biol
, vol.21
, pp. 452-460
-
-
Chekulaeva, M.1
Filipowicz, W.2
-
8
-
-
33644750115
-
MiRBase: MicroRNA sequences, targets and gene nomenclature
-
Griffiths-Jones S, Grocock RJ, van Dongen S, Bateman A, Enright AJ. 2006. miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res. 34:D140-44
-
(2006)
Nucleic Acids Res
, vol.34
-
-
Griffiths-Jones, S.1
Grocock, R.2
Jvan Dongen, S.3
Bateman, A.4
Enright, A.J.5
-
9
-
-
0027495519
-
The human phenolsulphotransferase polymorphism is determined by the level of expression of the enzyme protein
-
Jones AL, Roberts RC, Coughtrie MW. 1993. The human phenolsulphotransferase polymorphism is determined by the level of expression of the enzyme protein. Biochem. J. 296:287-90
-
(1993)
Biochem. J
, vol.296
, pp. 287-290
-
-
Jones, A.L.1
Roberts, R.C.2
Coughtrie, M.W.3
-
10
-
-
0346094457
-
Prediction of mammalian microRNA targets
-
Lewis BP, Shih IH, Jones-Rhoades MW, Bartel DP, Burge CB. 2003. Prediction of mammalian microRNA targets. Cell 115:787-98
-
(2003)
Cell
, vol.115
, pp. 787-798
-
-
Lewis, B.P.1
Shih, I.H.2
Jones-Rhoades, M.W.3
Bartel, D.P.4
Burge, C.B.5
-
11
-
-
20944450160
-
Combinatorial microRNA target predictions
-
Krek A, Gr?un D, Poy MN, Wolf R, Rosenberg L, et al. 2005. Combinatorial microRNA target predictions. Nat. Genet. 37:495-500
-
(2005)
Nat. Genet
, vol.37
, pp. 495-500
-
-
Krek, A.1
Grun, D.2
Poy, M.N.3
Wolf, R.4
Rosenberg, L.5
-
12
-
-
49949116902
-
The impact of microRNAs on protein output
-
Baek D, Vill?en J, Shin C, Camargo FD, Gygi SP, Bartel DP. 2008. The impact of microRNAs on protein output. Nature 455:64-71
-
(2008)
Nature
, vol.455
, pp. 64-71
-
-
Baek, D.1
Villen, J.2
Shin, C.3
Camargo, F.D.4
Gygi, S.P.5
Bartel, D.P.6
-
13
-
-
13944282215
-
Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs
-
Lim LP, Lau NC, Garrett-Engele P, Grimson A, Schelter JM, et al. 2005. Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature 433:769-73
-
(2005)
Nature
, vol.433
, pp. 769-773
-
-
Lim, L.P.1
Lau, N.C.2
Garrett-Engele, P.3
Grimson, A.4
Schelter, J.M.5
-
14
-
-
67749132423
-
Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps
-
Chi SW, Zang JB, Mele A, Darnell RB. 2009. Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps. Nature 460:479-86
-
(2009)
Nature
, vol.460
, pp. 479-486
-
-
Chi, S.W.1
Zang, J.B.2
Mele, A.3
Darnell, R.B.4
-
15
-
-
0028276386
-
Complete cDNA sequence of a human dioxin-inducible mRNA identifies a new gene subfamily of cytochrome P450 that maps to chromosome 2
-
Sutter TR, Tang YM, Hayes CL, Wo YY, Jabs EW, et al. 1994. Complete cDNA sequence of a human dioxin-inducible mRNA identifies a new gene subfamily of cytochrome P450 that maps to chromosome 2. J. Biol. Chem. 269:13092-99
-
(1994)
J. Biol. Chem
, vol.269
, pp. 13092-13099
-
-
Sutter, T.R.1
Tang, Y.M.2
Hayes, C.L.3
Wo, Y.Y.4
Jabs, E.W.5
-
16
-
-
0030008731
-
Activation of chemically diverse procarcinogens by human cytochrome P-450 1B1
-
Shimada T, Hayes CL, Yamazaki H, Amin S, Hecht SS, et al. 1996. Activation of chemically diverse procarcinogens by human cytochrome P-450 1B1. Cancer Res. 56:2979-84
-
(1996)
Cancer Res
, vol.56
, pp. 2979-2984
-
-
Shimada, T.1
Hayes, C.L.2
Yamazaki, H.3
Amin, S.4
Hecht, S.S.5
-
17
-
-
0029796550
-
17β-Estradiol hydroxylation catalyzed by human cytochrome P450 1B1
-
Hayes CL, Spink DC, Spink BC, Cao JQ, Walker NJ, Sutter TR. 1996. 17β-Estradiol hydroxylation catalyzed by human cytochrome P450 1B1. Proc. Natl. Acad. Sci. USA 93:9776-81
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 9776-9781
-
-
Hayes, C.L.1
Spink, D.C.2
Spink, B.C.3
Cao, J.Q.4
Walker, N.J.5
Sutter, T.R.6
-
19
-
-
0028234634
-
DNA single-strand breaks in kidneys of Syrian hamsters treated with steroidal estrogens: Hormone-induced free radical damage preceding renal malignancy
-
Han X, Liehr JG. 1994. DNA single-strand breaks in kidneys of Syrian hamsters treated with steroidal estrogens: hormone-induced free radical damage preceding renal malignancy. Carcinogenesis 15:997-1000
-
(1994)
Carcinogenesis
, vol.15
, pp. 997-1000
-
-
Han, X.1
Liehr, J.G.2
-
20
-
-
0034650264
-
Induction of uterine adenocarcinoma inCD-1mice by catechol estrogens
-
Newbold RR, Liehr JG. 2000. Induction of uterine adenocarcinoma inCD-1mice by catechol estrogens. Cancer Res. 60:235-37
-
(2000)
Cancer Res
, vol.60
, pp. 235-237
-
-
Newbold, R.R.1
Liehr, J.G.2
-
21
-
-
0032929043
-
Differential expression of CYP1A1, CYP1A2, CYP1B1 in human kidney tumours
-
Cheung YL, Kerr AC, McFadyen MC, Melvin WT, Murray GI. 1999. Differential expression of CYP1A1, CYP1A2, CYP1B1 in human kidney tumours. Cancer Lett. 139:199-205
-
(1999)
Cancer Lett
, vol.139
, pp. 199-205
-
-
Cheung, Y.L.1
Kerr, A.C.2
McFadyen, M.C.3
Melvin, W.T.4
Murray, G.I.5
-
22
-
-
0030812372
-
Tumor-specific expression of cytochrome P450 CYP1B1
-
Murray GI, Taylor MC, McFadyen MC, McKay JA, Greenlee WF, et al. 1997. Tumor-specific expression of cytochrome P450 CYP1B1. Cancer Res. 57:3026-31
-
(1997)
Cancer Res
, vol.57
, pp. 3026-3031
-
-
Murray, G.I.1
Taylor, M.C.2
McFadyen, M.C.3
McKay, J.A.4
Greenlee, W.F.5
-
23
-
-
33749487425
-
MicroRNA regulates the expression of human cytochrome P450 1B1
-
Tsuchiya Y, Nakajima M, Takagi S, Taniya T, Yokoi T. 2006. MicroRNA regulates the expression of human cytochrome P450 1B1. Cancer Res. 66:9090-98
-
(2006)
Cancer Res
, vol.66
, pp. 9090-9098
-
-
Tsuchiya, Y.1
Nakajima, M.2
Takagi, S.3
Taniya, T.4
Yokoi, T.5
-
24
-
-
2342516193
-
Human CYP1B1 is regulated by estradiol via estrogen receptor
-
Tsuchiya Y, Nakajima M, Kyo S, Kanaya T, Inoue M, Yokoi T. 2004. Human CYP1B1 is regulated by estradiol via estrogen receptor. Cancer Res. 64:3119-25
-
(2004)
Cancer Res
, vol.64
, pp. 3119-3125
-
-
Tsuchiya, Y.1
Nakajima, M.2
Kyo, S.3
Kanaya, T.4
Inoue, M.5
Yokoi, T.6
-
25
-
-
39149123560
-
CYP2E1 and oxidative liver injury by alcohol
-
Lu Y, Cederbaum AI. 2008. CYP2E1 and oxidative liver injury by alcohol. Free Radic. Biol.Med. 44:723-38
-
(2008)
Free Radic. Biol.Med
, vol.44
, pp. 723-738
-
-
Lu, Y.1
Cederbaum, A.I.2
-
26
-
-
0037938645
-
The cytochrome P-450 isoenzyme CYP2E1 in the biological processing of industrial chemicals: Consequences for occupational and environmental medicine
-
Bolt HM, Roos PH, Thier R. 2003. The cytochrome P-450 isoenzyme CYP2E1 in the biological processing of industrial chemicals: consequences for occupational and environmental medicine. Int. Arch. Occup. Environ. Health 76:174-85
-
(2003)
Int. Arch. Occup. Environ. Health
, vol.76
, pp. 174-185
-
-
Bolt, H.M.1
Roos, P.H.2
Thier, R.3
-
27
-
-
34547899883
-
Reverse transcriptase-PCR quantification of mRNA levels from cytochrome (CYP)1, CYP2 and CYP3 families in 22 different human tissues
-
Bìeche I, Narjoz C, Asselah T, Vacher S, Marcellin P, et al. 2007. Reverse transcriptase-PCR quantification of mRNA levels from cytochrome (CYP)1, CYP2 and CYP3 families in 22 different human tissues. Pharmacogenet. Genomics 17:731-42
-
(2007)
Pharmacogenet. Genomics
, vol.17
, pp. 731-742
-
-
Bìeche, I.1
Narjoz, C.2
Asselah, T.3
Vacher, S.4
Marcellin, P.5
-
28
-
-
0028237729
-
Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: Studies with liver microsomes of 30 Japanese and 30 Caucasians
-
Shimada T, Yamazaki H, Mimura M, Inui Y, Guengerich FP. 1994. Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians. J. Pharmacol. Exp. Ther. 270:414-23
-
(1994)
J. Pharmacol. Exp. Ther
, vol.270
, pp. 414-423
-
-
Shimada, T.1
Yamazaki, H.2
Mimura, M.3
Inui, Y.4
Guengerich, F.P.5
-
29
-
-
77449109225
-
Human CYP2E1 is regulated by miR-378
-
Mohri T, Nakajima M, Fukami T, Takamiya M, Aoki Y, Yokoi T. 2010. Human CYP2E1 is regulated by miR-378. Biochem. Pharmacol. 79:1045-52
-
(2010)
Biochem. Pharmacol
, vol.79
, pp. 1045-1052
-
-
Mohri, T.1
Nakajima, M.2
Fukami, T.3
Takamiya, M.4
Aoki, Y.5
Yokoi, T.6
-
30
-
-
38049103266
-
MicroRNA-378 promotes cell survival, tumor growth, and angiogenesis by targeting SuFu and Fs-1 expression
-
Lee DY, Deng Z, Wang CH, Yang BB. 2007. MicroRNA-378 promotes cell survival, tumor growth, and angiogenesis by targeting SuFu and Fs-1 expression. Proc. Natl. Acad. Sci. USA 104:20350-55
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 20350-20355
-
-
Lee, D.Y.1
Deng, Z.2
Wang, C.H.3
Yang, B.B.4
-
31
-
-
54949154476
-
MiRNA-directed regulation of VEGF and other angiogenic factors under hypoxia
-
Hua Z, Lv Q, Ye W, Wong CK, Cai G, et al. 2006. MiRNA-directed regulation of VEGF and other angiogenic factors under hypoxia. PLoS ONE 1:e116
-
(2006)
PLoS ONE
, vol.1
-
-
Hua, Z.1
Lv, Q.2
Ye, W.3
Wong, C.K.4
Cai, G.5
-
32
-
-
0024507690
-
Identification of a novel P450 expressed in rat lung: CDNA cloning and sequence, chromosome mapping, and induction by 3-methylcholanthrene
-
Kimura S, Kozak CA, Gonzalez FJ. 1989. Identification of a novel P450 expressed in rat lung: cDNA cloning and sequence, chromosome mapping, and induction by 3-methylcholanthrene. Biochemistry 28:3798-803
-
(1989)
Biochemistry
, vol.28
, pp. 3798-3803
-
-
Kimura, S.1
Kozak, C.A.2
Gonzalez, F.J.3
-
33
-
-
13944282327
-
Cytochrome P450 enzymes as catalysts of metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, a tobacco specific carcinogen
-
Jalas JR, Hecht SS, Murphy SE. 2005. Cytochrome P450 enzymes as catalysts of metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, a tobacco specific carcinogen. Chem. Res. Toxicol. 18:95-110
-
(2005)
Chem. Res. Toxicol
, vol.18
, pp. 95-110
-
-
Jalas, J.R.1
Hecht, S.S.2
Murphy, S.E.3
-
34
-
-
57349134379
-
Differential expression of microRNAs in earlystage neoplastic transformation in the lungs of F344 rats chronically treated with the tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone
-
Kalscheuer S, Zhang X, Zeng Y, Upadhyaya P. 2008. Differential expression of microRNAs in earlystage neoplastic transformation in the lungs of F344 rats chronically treated with the tobacco carcinogen 4-(methylnitrosamino)-1-(3- pyridyl)-1-butanone. Carcinogenesis 29:2394-99
-
(2008)
Carcinogenesis
, vol.29
, pp. 2394-2399
-
-
Kalscheuer, S.1
Zhang, X.2
Zeng, Y.3
Upadhyaya, P.4
-
35
-
-
34548803950
-
MicroRNA-34b and microRNA-34c are targets of p53 and cooperate in control of cell proliferation and adhesion-independent growth
-
Corney DC, Flesken-Nikitin A, Godwin AK, WangW, Nikitin AY. 2007. microRNA-34b and microRNA-34c are targets of p53 and cooperate in control of cell proliferation and adhesion-independent growth. Cancer Res. 67:8433-38
-
(2007)
Cancer Res
, vol.67
, pp. 8433-8438
-
-
Corney, D.C.1
Flesken-Nikitin, A.2
Godwin, A.K.3
Wang, W.4
Nikitin, A.Y.5
-
36
-
-
34250851115
-
A microRNA component of the p53 tumour suppressor network
-
He L, He X, Lim LP, de Stanchina E, Xuan Z, et al. 2007. A microRNA component of the p53 tumour suppressor network. Nature 447:1130-34
-
(2007)
Nature
, vol.447
, pp. 1130-1134
-
-
He, L.1
He, X.2
Lim, L.3
Pde Stanchina, E.4
Xuan, Z.5
-
37
-
-
0030935086
-
Use of in vitro and in vivo data to estimate the likelihood of metabolic pharmacokinetic interactions
-
Bertz RJ, Granneman GR. 1997. Use of in vitro and in vivo data to estimate the likelihood of metabolic pharmacokinetic interactions. Clin. Pharmacokinet. 32:210-58
-
(1997)
Clin. Pharmacokinet
, vol.32
, pp. 210-258
-
-
Bertz, R.J.1
Granneman, G.R.2
-
38
-
-
0025094496
-
Evidence for involvement of multiple forms of cytochrome P-450 in aflatoxin B1 metabolism in human liver
-
Forrester LM, Neal GE, Judah DJ, Glancey MJ, Wolf CR. 1990. Evidence for involvement of multiple forms of cytochrome P-450 in aflatoxin B1 metabolism in human liver. Proc.Natl. Acad. Sci. USA87:8306-10
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 8306-8310
-
-
Forrester, L.M.1
Neal, G.E.2
Judah, D.J.3
Glancey, M.J.4
Wolf, C.R.5
-
39
-
-
0024326433
-
Role of individual human cytochrome P-450 enzymes in the bioactivation of benzo(a)pyrene 7, 8-dihydroxy-7, 8-dihydrobenzo(a)pyrene, and other dihydrodiol derivatives of polycyclic aromatic hydrocarbons
-
Shimada T, Martin MV, Pruess-Schwartz D, Marnett LJ, Guengerich FP. 1989. Role of individual human cytochrome P-450 enzymes in the bioactivation of benzo(a)pyrene, 7, 8-dihydroxy-7, 8-dihydrobenzo(a)pyrene, and other dihydrodiol derivatives of polycyclic aromatic hydrocarbons. Cancer Res. 49:6304-12
-
(1989)
Cancer Res
, vol.49
, pp. 6304-6312
-
-
Shimada, T.1
Martin, M.V.2
Pruess-Schwartz, D.3
Marnett, L.J.4
Guengerich, F.P.5
-
40
-
-
0036089341
-
Co-regulation of CYP3A4 and CYP3A5 and contribution to hepatic and intestinal midazolam metabolism
-
Lin YS, Dowling AL, Quigley SD, Farin FM, Zhang J, et al. 2002. Co-regulation of CYP3A4 and CYP3A5 and contribution to hepatic and intestinal midazolam metabolism. Mol. Pharmacol. 62:162-72
-
(2002)
Mol. Pharmacol
, vol.62
, pp. 162-172
-
-
Lin, Y.S.1
Dowling, A.L.2
Quigley, S.D.3
Farin, F.M.4
Zhang, J.5
-
41
-
-
0142250945
-
Genotype-phenotype associations for common CYP3A4 and CYP3A5 variants in the basal and induced metabolism of midazolam in European-and African-American men and women
-
Floyd MD, Gervasini G, Masica AL, Mayo G, George AL Jr, et al. 2003. Genotype-phenotype associations for common CYP3A4 and CYP3A5 variants in the basal and induced metabolism of midazolam in European-and African-American men and women. Pharmacogenetics 13:596-606
-
(2003)
Pharmacogenetics
, vol.13
, pp. 596-606
-
-
Floyd, M.D.1
Gervasini, G.2
Masica, A.L.3
Mayo, G.4
George Jr., A.L.5
-
42
-
-
27544486754
-
Phenotypegenotype variability in the human CYP3A locus as assessed by the probe drug quinine and analyses of variant CYP3A4 alleles
-
Rodríguez-Antona C, Sayi JG, Gustafsson LL, Bertilsson L, Ingelman-Sundberg M. 2005. Phenotypegenotype variability in the human CYP3A locus as assessed by the probe drug quinine and analyses of variant CYP3A4 alleles. Biochem. Biophys. Res. Commun. 338:299-305
-
(2005)
Biochem. Biophys. Res. Commun
, vol.338
, pp. 299-305
-
-
Rodríguez-Antona, C.1
Sayi, J.G.2
Gustafsson, L.L.3
Bertilsson, L.4
Ingelman-Sundberg, M.5
-
43
-
-
0036219998
-
Common allelic variants of cytochrome P4503A4 and their prevalence in different populations
-
Lamba JK, Lin YS, ThummelK, Daly A, Watkins PB, et al. 2002. Common allelic variants of cytochrome P4503A4 and their prevalence in different populations. Pharmacogenetics 12:121-32
-
(2002)
Pharmacogenetics
, vol.12
, pp. 121-132
-
-
Lamba, J.K.1
Lin, Y.S.2
Thummel, K.3
Daly, A.4
Watkins, P.B.5
-
44
-
-
33846864449
-
Transcriptional regulation and expression of CYP3A4 in hepatocytes
-
Martínez-Jimenez CP, Jover R, Donato MT, Castell JV, Gömez-Lechön MJ. 2007. Transcriptional regulation and expression of CYP3A4 in hepatocytes. Curr. Drug Metab. 8:185-94
-
(2007)
Curr. Drug Metab
, vol.8
, pp. 185-194
-
-
Martínez-Jimenez, C.P.1
Jover, R.2
Donato, M.T.3
Castell, J.V.4
Gömez-Lechön, M.J.5
-
45
-
-
44349182094
-
Post-transcriptional regulation of human pregnane X receptor by microRNA affects the expression of cytochrome P450 3A4
-
Takagi S, Nakajima M, Mohri T, Yokoi T. 2008. Post-transcriptional regulation of human pregnane X receptor by microRNA affects the expression of cytochrome P450 3A4. J. Biol. Chem. 283:9674-80
-
(2008)
J. Biol. Chem
, vol.283
, pp. 9674-9680
-
-
Takagi, S.1
Nakajima, M.2
Mohri, T.3
Yokoi, T.4
-
46
-
-
70349268327
-
MicroRNAs regulateCYP3A4 expression via direct and indirect targeting
-
PanYZ, GaoW, YuAM.2009. MicroRNAs regulateCYP3A4 expression via direct and indirect targeting. Drug Metab. Dispos. 37:2112-17
-
(2009)
Drug Metab. Dispos
, vol.37
, pp. 2112-2117
-
-
Pan, Y.Z.1
Gao, W.2
Yu, A.M.3
-
47
-
-
23744437421
-
Noncalcemic actions of vitamin Dreceptor ligands
-
Nagpal S, Na S, Rathnachalam R. 2005. Noncalcemic actions of vitamin Dreceptor ligands. Endocr. Rev. 26:662-87
-
(2005)
Endocr. Rev
, vol.26
, pp. 662-687
-
-
Nagpal, S.1
Na, S.2
Rathnachalam, R.3
-
48
-
-
34548202165
-
Vitamin D signaling pathways in cancer: Potential for anticancer therapeutics
-
Deeb KK, Trump DL, Johnson CS. 2007. Vitamin D signaling pathways in cancer: potential for anticancer therapeutics. Nat. Rev. Cancer 7:684-700
-
(2007)
Nat. Rev. Cancer
, vol.7
, pp. 684-700
-
-
Deeb, K.K.1
Trump, D.L.2
Johnson, C.S.3
-
49
-
-
33845291140
-
Novel patterns of genome rearrangement and their association with survival in breast cancer
-
Hicks J, KrasnitzA, Lakshmi B, Navin NE, Riggs M, et al. 2006. Novel patterns of genome rearrangement and their association with survival in breast cancer. Genome Res. 16:1465-79
-
(2006)
Genome Res
, vol.16
, pp. 1465-1479
-
-
Hicks, J.1
Krasnitz, A.2
Lakshmi, B.3
Navin, N.E.4
Riggs, M.5
-
50
-
-
33746822914
-
25(OH)D3 and 1, 25(OH)2D3 serum concentration and breast tissue expression of 1α-hydroxylase, 24-hydroxylase and Vitamin D receptor in women with and without breast cancer
-
de Lyra EC, de Silva IA, Katayama ML, Brentani MM, Nonogaki S, et al. 2006. 25(OH)D3 and 1, 25(OH)2D3 serum concentration and breast tissue expression of 1α-hydroxylase, 24-hydroxylase and Vitamin D receptor in women with and without breast cancer. J. Steroid Biochem. Mol. Biol. 100:184-92
-
(2006)
J. Steroid Biochem. Mol. Biol
, vol.100
, pp. 184-192
-
-
De Lyra, E.1
Cde Silva, I.A.2
Katayama, M.L.3
Brentani, M.M.4
Nonogaki, S.5
-
52
-
-
34447514029
-
Vitamin D deficiency
-
Holick MF. 2007. Vitamin D deficiency. N. Engl. J. Med. 357:266-81
-
(2007)
N. Engl. J. Med
, vol.357
, pp. 266-281
-
-
Holick, M.F.1
-
53
-
-
0036379364
-
Analysis of vitamin D-receptor (VDR) and retinoid X-receptor αin breast cancer
-
Friedrich M, Axt-Fliedner R, Villena-Heinsen C, Tilgen W, Schmidt W, Reichrath J. 2002. Analysis of vitamin D-receptor (VDR) and retinoid X-receptor αin breast cancer. Histochem. J. 34:35-40
-
(2002)
Histochem. J
, vol.34
, pp. 35-40
-
-
Friedrich, M.1
Axt-Fliedner, R.2
Villena-Heinsen, C.3
Tilgen, W.4
Schmidt, W.5
Reichrath, J.6
-
54
-
-
33344474685
-
25-Hydroxyvitamin D3 1α-hydroxylase and vitamin D receptor expression in papillary thyroid carcinoma
-
Khadzkou K, Buchwald P, Westin G, Dralle H, Akerstr öm G, Hellman P. 2006. 25-Hydroxyvitamin D3 1α-hydroxylase and vitamin D receptor expression in papillary thyroid carcinoma. J. Histochem. Cytochem. 54:355-61
-
(2006)
J. Histochem. Cytochem
, vol.54
, pp. 355-361
-
-
Khadzkou, K.1
Buchwald, P.2
Westin, G.3
Dralle, H.4
Akerström, G.5
Hellman, P.6
-
55
-
-
70349333224
-
Human CYP24 catalyzing the inactivation of calcitriol is post-transcriptionally regulated by miR-125b
-
Komagata S, Nakajima M, Takagi S, Mohri T, Taniya T, Yokoi T. 2009. Human CYP24 catalyzing the inactivation of calcitriol is post-transcriptionally regulated by miR-125b. Mol. Pharmacol. 76:702-9
-
(2009)
Mol. Pharmacol
, vol.76
, pp. 702-709
-
-
Komagata, S.1
Nakajima, M.2
Takagi, S.3
Mohri, T.4
Taniya, T.5
Yokoi, T.6
-
56
-
-
68249147449
-
MicroRNA regulates human vitamin D receptor
-
Mohri T, Nakajima M, Takagi S, Komagata S, Yokoi T. 2009. MicroRNA regulates human vitamin D receptor. Int. J. Cancer 125:1328-33
-
(2009)
Int. J. Cancer
, vol.125
, pp. 1328-1333
-
-
Mohri, T.1
Nakajima, M.2
Takagi, S.3
Komagata, S.4
Yokoi, T.5
-
57
-
-
33144490646
-
A microRNA expression signature of human solid tumors defines cancer gene targets
-
Volinia S, Calin GA, Liu CG, Ambs S, Cimmino A, et al. 2006. A microRNA expression signature of human solid tumors defines cancer gene targets. Proc. Natl. Acad. Sci. USA 103:2257-61
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 2257-2261
-
-
Volinia, S.1
Calin, G.A.2
Liu, C.G.3
Ambs, S.4
Cimmino, A.5
-
58
-
-
42249106086
-
Regulation of hepatocyte nuclear factor 4α-mediated transcription
-
Gonzalez FJ. 2008. Regulation of hepatocyte nuclear factor 4α-mediated transcription. Drug Metab. Pharmacokinet. 23:2-7
-
(2008)
Drug Metab. Pharmacokinet
, vol.23
, pp. 2-7
-
-
Gonzalez, F.J.1
-
59
-
-
34848824067
-
Role of human hepatocyte nuclear factor 4αin the expression of drug-metabolizing enzymes and transporters in human hepatocytes assessed by use of small interfering RNA
-
Kamiyama Y, Matsubara T, Yoshinari K, Nagata K, Kamimura H, Yamazoe Y. 2007. Role of human hepatocyte nuclear factor 4αin the expression of drug-metabolizing enzymes and transporters in human hepatocytes assessed by use of small interfering RNA. Drug Metab. Pharmacokinet. 22:287-98
-
(2007)
Drug Metab. Pharmacokinet
, vol.22
, pp. 287-298
-
-
Kamiyama, Y.1
Matsubara, T.2
Yoshinari, K.3
Nagata, K.4
Kamimura, H.5
Yamazoe, Y.6
-
60
-
-
77951157723
-
MicroRNAs regulate human hepatocyte nuclear factor 4α, modulating the expression of metabolic enzymes and cell cycle
-
Takagi S, Nakajima M, Kida K, Yamaura Y, Fukami T, Yokoi T. 2010. MicroRNAs regulate human hepatocyte nuclear factor 4α, modulating the expression of metabolic enzymes and cell cycle. J. Biol. Chem. 285:4415-22
-
(2010)
J. Biol. Chem
, vol.285
, pp. 4415-4422
-
-
Takagi, S.1
Nakajima, M.2
Kida, K.3
Yamaura, Y.4
Fukami, T.5
Yokoi, T.6
-
61
-
-
33750027681
-
Cytochrome P450s and cholesterol homeostasis
-
Pikuleva IA. 2006. Cytochrome P450s and cholesterol homeostasis. Pharmacol. Ther. 112:761-73
-
(2006)
Pharmacol. Ther
, vol.112
, pp. 761-773
-
-
Pikuleva, I.A.1
-
62
-
-
0029789568
-
Functional interference between hypoxia and dioxin signal transduction pathways: Competition for recruitment of the Arnt transcription factor
-
Gradin K, McGuire J, Wenger RH, Kvietikova I, Whitelaw ML, et al. 1996. Functional interference between hypoxia and dioxin signal transduction pathways: competition for recruitment of the Arnt transcription factor. Mol. Cell. Biol. 16:5221-31
-
(1996)
Mol. Cell. Biol
, vol.16
, pp. 5221-5231
-
-
Gradin, K.1
McGuire, J.2
Wenger, R.H.3
Kvietikova, I.4
Whitelaw, M.L.5
-
63
-
-
33751162428
-
Curcumin inhibits hypoxia-inducible factor-1 by degrading aryl hydrocarbon receptor nuclear translocator: A mechanism of tumor growth inhibition
-
Choi H, Chun YS, Kim SW, Kim MS, Park JW. 2006. Curcumin inhibits hypoxia-inducible factor-1 by degrading aryl hydrocarbon receptor nuclear translocator: a mechanism of tumor growth inhibition. Mol. Pharmacol. 70:1664-71
-
(2006)
Mol. Pharmacol
, vol.70
, pp. 1664-1671
-
-
Choi, H.1
Chun, Y.S.2
Kim, S.W.3
Kim, M.S.4
Park, J.W.5
-
64
-
-
57349185988
-
Curcumin attenuates cytochrome P450 induction in response to 2,3,7, 8-tetrachlorodibenzo-p-dioxin by ROS-dependently degrading AhR and ARNT
-
Choi H, Chun YS, Shin YJ, Ye SK, Kim MS, Park JW. 2008. Curcumin attenuates cytochrome P450 induction in response to 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin by ROS-dependently degrading AhR and ARNT. Cancer Sci. 99:2518-24
-
(2008)
Cancer Sci
, vol.99
, pp. 2518-2524
-
-
Choi, H.1
Chun, Y.S.2
Shin, Y.J.3
Ye, S.K.4
Kim, M.S.5
Park, J.W.6
-
65
-
-
84859976379
-
Aryl hydrocarbon nuclear translocator in human liver is regulated by miR-24
-
Oda Y, NakajimaM, Mohri T, Takamiya M, Aoki Y, et al. 2012. Aryl hydrocarbon nuclear translocator in human liver is regulated by miR-24. Toxicol. Appl. Pharmacol. 260:222-31
-
(2012)
Toxicol. Appl. Pharmacol
, vol.260
, pp. 222-231
-
-
Oda, Y.1
Nakajima, M.2
Mohri, T.3
Takamiya, M.4
Aoki, Y.5
-
66
-
-
34250843675
-
The micro-ribonucleic acid (miRNA) miR-206 targets the human estrogen receptor-α(ERα) and represses ERαmessenger RNA and protein expression in breast cancer cell lines
-
Adams BD, Furneaux H, White BA. 2007. The micro-ribonucleic acid (miRNA) miR-206 targets the human estrogen receptor-α(ERα) and represses ERαmessenger RNA and protein expression in breast cancer cell lines. Mol. Endocrinol. 21:1132-47
-
(2007)
Mol. Endocrinol
, vol.21
, pp. 1132-1147
-
-
Adams, B.D.1
Furneaux, H.2
White, B.A.3
-
67
-
-
57649174634
-
MicroRNA-221/222 negatively regulates estrogen receptor αand is associated with tamoxifen resistance in breast cancer
-
Zhao JJ, Lin J, Yang H, Kong W, He L, et al. 2008. MicroRNA-221/222 negatively regulates estrogen receptor αand is associated with tamoxifen resistance in breast cancer. J. Biol. Chem. 283:31079-86
-
(2008)
J. Biol. Chem
, vol.283
, pp. 31079-31086
-
-
Zhao, J.J.1
Lin, J.2
Yang, H.3
Kong, W.4
He, L.5
-
68
-
-
77949617195
-
An estrogen receptor αsuppressor, microRNA-22, is downregulated in estrogen receptor α-positive human breast cancer cell lines and clinical samples
-
Xiong J, Yu D, Wei N, Fu H, Cai T, et al. 2010. An estrogen receptor αsuppressor, microRNA-22, is downregulated in estrogen receptor α-positive human breast cancer cell lines and clinical samples. FEBS J. 277:1684-94
-
(2010)
FEBS J
, vol.277
, pp. 1684-1694
-
-
Xiong, J.1
Yu, D.2
Wei, N.3
Fu, H.4
Cai, T.5
-
69
-
-
67650135755
-
MiR-22 inhibits estrogen signaling by directly targeting the estrogen receptor αmRNA
-
Pandey DP, Picard D. 2009. miR-22 inhibits estrogen signaling by directly targeting the estrogen receptor αmRNA. Mol. Cell. Biol. 29:3783-90
-
(2009)
Mol. Cell. Biol
, vol.29
, pp. 3783-3790
-
-
Pandey, D.P.1
Picard, D.2
-
70
-
-
78549249846
-
Epigenetically deregulated microRNA-375 is involved in a positive feedback loop with estrogen receptor α in breast cancer cells
-
de Souza Rocha Simonini P, Breiling A, Gupta N, Malekpour M, Youns M, et al. 2010. Epigenetically deregulated microRNA-375 is involved in a positive feedback loop with estrogen receptor α in breast cancer cells. Cancer Res. 70:9175-84
-
(2010)
Cancer Res
, vol.70
, pp. 9175-9184
-
-
De Souza Rocha Simonini, P.1
Breiling, A.2
Gupta, N.3
Malekpour, M.4
Youns, M.5
-
71
-
-
77954497664
-
MicroRNA-27a indirectly regulates estrogen receptor αexpression and hormone responsiveness inMCF-7 breast cancer cells
-
Li X, Mertens-Talcott SU, Zhang S, Kim K, Ball J, Safe S. 2010. MicroRNA-27a indirectly regulates estrogen receptor αexpression and hormone responsiveness inMCF-7 breast cancer cells. Endocrinology 151:2462-73
-
(2010)
Endocrinology
, vol.151
, pp. 2462-2473
-
-
Li, X.1
Mertens-Talcott, S.U.2
Zhang, S.3
Kim, K.4
Ball, J.5
Safe, S.6
-
72
-
-
80054764011
-
PPARα is regulated by miR-21 and miR-27b in human liver
-
Kida K, Nakajima M, Mohri T, Oda Y, Takagi S, et al. 2011. PPARα is regulated by miR-21 and miR-27b in human liver. Pharm. Res. 28:2467-76
-
(2011)
Pharm. Res
, vol.28
, pp. 2467-2476
-
-
Kida, K.1
Nakajima, M.2
Mohri, T.3
Oda, Y.4
Takagi, S.5
-
73
-
-
70350125874
-
MicroRNA miR-27b impairs human adipocyte differentiation and targets PPARγ
-
Karbiener M, Fischer C, Nowitsch S, Opriessnig P, Papak C, et al. 2009. microRNA miR-27b impairs human adipocyte differentiation and targets PPARγ. Biochem. Biophys. Res. Commun. 390:247-51
-
(2009)
Biochem. Biophys. Res. Commun
, vol.390
, pp. 247-251
-
-
Karbiener, M.1
Fischer, C.2
Nowitsch, S.3
Opriessnig, P.4
Papak, C.5
-
74
-
-
77951219696
-
MicroRNA-27b contributes to lipopolysaccharide-mediated peroxisome proliferator-activated preceptor γ (PPARγ) mRNA destabilization
-
Jennewein C, von Knethen A, Schmid T, Brune B. 2010. MicroRNA-27b contributes to lipopolysaccharide-mediated peroxisome proliferator-activated preceptor γ (PPARγ) mRNA destabilization. J. Biol. Chem. 285:11846-53
-
(2010)
J. Biol. Chem
, vol.285
, pp. 11846-11853
-
-
Jennewein, C.1
Von Knethen, A.2
Schmid, T.3
Brune, B.4
-
75
-
-
76349089521
-
MiR-27a is a negative regulator of adipocyte differentiation via suppressing PPARγexpression
-
Kim SY, Kim AY, Lee HW, Son YH, Lee GY, et al. 2010. miR-27a is a negative regulator of adipocyte differentiation via suppressing PPARγexpression. Biochem. Biophys. Res. Commun. 392:323-28
-
(2010)
Biochem. Biophys. Res. Commun
, vol.392
, pp. 323-328
-
-
Kim, S.Y.1
Kim, A.Y.2
Lee, H.W.3
Son, Y.H.4
Lee, G.Y.5
-
76
-
-
63049108381
-
A role of miR-27 in the regulation of adipogenesis
-
Lin Q, Gao Z, Alarcon RM, Ye J, Yun Z. 2009. A role of miR-27 in the regulation of adipogenesis. FEBS J. 276:2348-58
-
(2009)
FEBS J
, vol.276
, pp. 2348-2358
-
-
Lin, Q.1
Gao, Z.2
Alarcon, R.M.3
Ye, J.4
Yun, Z.5
-
77
-
-
59849084351
-
Over-expressedmicroRNA-27a and 27b influence fat accumulation and cell proliferation during rat hepatic stellate cell activation
-
Ji J, Zhang J, Huang G, Qian J, Wang X, Mei S. 2009. Over- expressedmicroRNA-27a and 27b influence fat accumulation and cell proliferation during rat hepatic stellate cell activation. FEBS Lett. 583:759-66
-
(2009)
FEBS Lett
, vol.583
, pp. 759-766
-
-
Ji, J.1
Zhang, J.2
Huang, G.3
Qian, J.4
Wang, X.5
Mei, S.6
-
78
-
-
0035793045
-
Impaired adipogenesis and lipolysis in the mouse upon selective ablation of the retinoid X receptor α mediated by a tamoxifen-inducible chimeric Cre recombinase (Cre-ERT2) in adipocytes
-
Imai T, Jiang M, Chambon P, Metzger D. 2001. Impaired adipogenesis and lipolysis in the mouse upon selective ablation of the retinoid X receptor α mediated by a tamoxifen-inducible chimeric Cre recombinase (Cre-ERT2) in adipocytes. Proc. Natl. Acad. Sci. USA 98:224-28
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 224-228
-
-
Imai, T.1
Jiang, M.2
Chambon, P.3
Metzger, D.4
-
80
-
-
67649511946
-
MicroRNA-222 regulates cell invasion by targeting matrix metalloproteinase 1 (MMP1) andmanganese superoxide dismutase 2 (SOD2) in tongue squamous cell carcinoma cell lines
-
Liu X, Yu J, Jiang L, Wang A, Shi F, et al. 2009. MicroRNA-222 regulates cell invasion by targeting matrix metalloproteinase 1 (MMP1) andmanganese superoxide dismutase 2 (SOD2) in tongue squamous cell carcinoma cell lines. Cancer Genomics Proteomics 6:131-39
-
(2009)
Cancer Genomics Proteomics
, vol.6
, pp. 131-139
-
-
Liu, X.1
Yu, J.2
Jiang, L.3
Wang, A.4
Shi, F.5
-
81
-
-
78650982065
-
Mir-17 suppresses tumorigenicity of prostate cancer by inhibiting mitochondrial antioxidant enzymes
-
Xu Y, Fang F, Zhang J, Josson S, St. Clair WH, St. Clair DK. 2010. mir-17 suppresses tumorigenicity of prostate cancer by inhibiting mitochondrial antioxidant enzymes. PLoS ONE 12:e14356
-
(2010)
PLoS ONE
, vol.12
-
-
Xu, Y.1
Fang, F.2
Zhang, J.3
Josson, S.4
St. Clair, W.H.5
St. Clair, D.K.6
-
82
-
-
48649102010
-
Identification of hypoxiainducible factor-1αas a novel target for miR-17-92 microRNA cluster
-
Taguchi A, Yanagisawa K, Tanaka M, Cao K, Matsuyama Y, et al. 2008. Identification of hypoxiainducible factor-1αas a novel target for miR-17-92 microRNA cluster. Cancer Res. 68:5540-45
-
(2008)
Cancer Res
, vol.68
, pp. 5540-5545
-
-
Taguchi, A.1
Yanagisawa, K.2
Tanaka, M.3
Cao, K.4
Matsuyama, Y.5
-
83
-
-
34250163202
-
Peroxisome proliferatoractivated receptor α regulates a microRNA-mediated signaling cascade responsible for hepatocellular proliferation
-
Shah YM, Morimura K, Yang Q, Tanabe T, Takagi M, Gonzalez FJ. 2007. Peroxisome proliferatoractivated receptor α regulates a microRNA-mediated signaling cascade responsible for hepatocellular proliferation. Mol. Cell. Biol. 27:4238-47
-
(2007)
Mol. Cell. Biol
, vol.27
, pp. 4238-4247
-
-
Shah, Y.M.1
Morimura, K.2
Yang, Q.3
Tanabe, T.4
Takagi, M.5
Gonzalez, F.J.6
-
84
-
-
0038367669
-
Activation of Nrf2 and accumulation of ubiquitinated A170 by arsenic in osteoblasts
-
Aono J, Yanagawa T, Itoh K, Li B, Yoshida H, et al. 2003. Activation of Nrf2 and accumulation of ubiquitinated A170 by arsenic in osteoblasts. Biochem. Biophys. Res. Commun. 305:271-77
-
(2003)
Biochem. Biophys. Res. Commun
, vol.305
, pp. 271-277
-
-
Aono, J.1
Yanagawa, T.2
Itoh, K.3
Li, B.4
Yoshida, H.5
-
85
-
-
33845312687
-
MicroRNA responses to cellular stress
-
Marsit CJ, Eddy K, Kelsey KT. 2006. MicroRNA responses to cellular stress. Cancer Res. 66:10843-48
-
(2006)
Cancer Res
, vol.66
, pp. 10843-10848
-
-
Marsit, C.J.1
Eddy, K.2
Kelsey, K.T.3
-
86
-
-
35648945351
-
Changes of micro-RNA expression in rat liver treated by acetaminophen or carbon tetrachloride: Regulating role of micro-RNA for RNA expression
-
Fukushima T, Hamada Y, Yamada H, Horii I. 2007. Changes of micro-RNA expression in rat liver treated by acetaminophen or carbon tetrachloride: regulating role of micro-RNA for RNA expression. J. Toxicol. Sci. 32:401-9
-
(2007)
J. Toxicol. Sci
, vol.32
, pp. 401-409
-
-
Fukushima, T.1
Hamada, Y.2
Yamada, H.3
Horii, I.4
-
87
-
-
82755189770
-
Dose-responsiveness and persistence of microRNA expression alterations induced by cigarette smoke in mouse lung
-
Izzotti A, Larghero P, Longobardi M, Cartiglia C, Camoirano A, et al. 2011. Dose-responsiveness and persistence of microRNA expression alterations induced by cigarette smoke in mouse lung. Mutat. Res. 717:9-16
-
(2011)
Mutat. Res
, vol.717
, pp. 9-16
-
-
Izzotti, A.1
Larghero, P.2
Longobardi, M.3
Cartiglia, C.4
Camoirano, A.5
-
88
-
-
60549084170
-
MicroRNAs as modulators of smoking-induced gene expression changes in human airway epithelium
-
Schembri F, Sridhar S, Perdomo C, Gustafson AM, Zhang X, et al. 2009. MicroRNAs as modulators of smoking-induced gene expression changes in human airway epithelium. Proc. Natl. Acad. Sci. USA 106:2319-24
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 2319-2324
-
-
Schembri, F.1
Sridhar, S.2
Perdomo, C.3
Gustafson, A.M.4
Zhang, X.5
-
89
-
-
38449116456
-
MicroRNAs in adult rodent liver are refractory to dioxin treatment
-
Moffat ID, Boutros PC, Celius T, Linden J, Pohjanvirta R, Okey AB. 2007. microRNAs in adult rodent liver are refractory to dioxin treatment. Toxicol. Sci. 99:470-87
-
(2007)
Toxicol. Sci
, vol.99
, pp. 470-487
-
-
Moffat, I.D.1
Boutros, P.C.2
Celius, T.3
Linden, J.4
Pohjanvirta, R.5
Okey, A.B.6
-
90
-
-
80051699704
-
Involvement of microRNAs in dioxin-induced liver damage in the mouse
-
Yoshioka W, Higashiyama W, Tohyama C. 2011. Involvement of microRNAs in dioxin-induced liver damage in the mouse. Toxicol. Sci. 122:457-65
-
(2011)
Toxicol. Sci
, vol.122
, pp. 457-465
-
-
Yoshioka, W.1
Higashiyama, W.2
Tohyama, C.3
-
91
-
-
79957756390
-
Lack of change in microRNA expression in adult mouse liver following treatment with benzo(a)pyrene despite robust mRNA transcriptional response
-
Yauk CL, Jackson K, Malowany M, Williams A. 2011. Lack of change in microRNA expression in adult mouse liver following treatment with benzo(a)pyrene despite robust mRNA transcriptional response. Mutat. Res. 722:131-39
-
(2011)
Mutat. Res
, vol.722
, pp. 131-139
-
-
Yauk, C.L.1
Jackson, K.2
Malowany, M.3
Williams, A.4
-
92
-
-
84855467600
-
Hepatic m RNA, micro RNA, and miR-34a-target responses in mice after 28 days exposure to doses of benzo(a)pyrene that elicit DNA damage and mutation
-
Malik AI, Williams A, Lemieux CL, White PA, Yauk CL. 2012. Hepatic m RNA, micro RNA, and miR-34a-target responses in mice after 28 days exposure to doses of benzo(a)pyrene that elicit DNA damage and mutation. Environ. Mol. Mutagen. 53:10-21
-
(2012)
Environ. Mol. Mutagen
, vol.53
, pp. 10-21
-
-
Malik, A.I.1
Williams, A.2
Lemieux, C.L.3
White, P.A.4
Yauk, C.L.5
-
93
-
-
79957824357
-
Pulmonary gene and microRNA expression changes in mice exposed to benzo(a)pyrene by oral gavage
-
Halappanavar S, WuD, Williams A, Kuo B, Godschalk RW, et al. 2011. Pulmonary gene and microRNA expression changes in mice exposed to benzo(a)pyrene by oral gavage. Toxicology 285:133-41
-
(2011)
Toxicology
, vol.285
, pp. 133-141
-
-
Halappanavar, S.1
Wu, D.2
Williams, A.3
Kuo Godschalk B, R.W.4
-
94
-
-
84862968214
-
Aberrant expression of miR-638 contributes to benzo(a)pyrene-induced human cell transformation
-
Li D, Wang Q, Liu C, Duan H, Zeng X, et al. 2012. Aberrant expression of miR-638 contributes to benzo(a)pyrene-induced human cell transformation. Toxicol. Sci. 125:382-91
-
(2012)
Toxicol. Sci
, vol.125
, pp. 382-391
-
-
Li, D.1
Wang, Q.2
Liu, C.3
Duan, H.4
Zeng, X.5
-
95
-
-
0028588925
-
Short-term toxicity of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin in laboratory animals: Effects, mechanisms, and animal models
-
Pohjanvirta R, Tuomisto J. 1994. Short-term toxicity of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin in laboratory animals: effects, mechanisms, and animal models. Pharmacol. Rev. 46:483-549
-
(1994)
Pharmacol. Rev
, vol.46
, pp. 483-549
-
-
Pohjanvirta, R.1
Tuomisto, J.2
-
96
-
-
84860319933
-
MiRNA-34 intrinsically links p53 tumor suppressor and Wnt signaling
-
Cha YH, Kim NH, Park C, Lee I, Kim HS, Yook JI. 2012. miRNA-34 intrinsically links p53 tumor suppressor and Wnt signaling. Cell Cycle 11:1273-81
-
(2012)
Cell Cycle
, vol.11
, pp. 1273-1281
-
-
Cha, Y.H.1
Kim, N.H.2
Park, C.3
Lee, I.4
Kim, H.S.5
Yook, J.I.6
-
97
-
-
77249177182
-
Differential mutagenicity of aflatoxin B1 in the liver of neonatal and adult mice
-
Chen T, Heflich RH, Moore MM, Mei N. 2010. Differential mutagenicity of aflatoxin B1 in the liver of neonatal and adult mice. Environ. Mol. Mutagen. 51:156-63
-
(2010)
Environ. Mol. Mutagen
, vol.51
, pp. 156-163
-
-
Chen, T.1
Heflich, R.H.2
Moore, M.M.3
Mei, N.4
-
98
-
-
0025828517
-
Selective G to T mutations of p53 gene in hepatocellular carcinoma from southern Africa
-
Bressac B, Kew M, Wands J, Ozturk M. 1991. Selective G to T mutations of p53 gene in hepatocellular carcinoma from southern Africa. Nature 350:429-31
-
(1991)
Nature
, vol.350
, pp. 429-431
-
-
Bressac, B.1
Kew, M.2
Wands, J.3
Ozturk, M.4
-
99
-
-
34247164636
-
Induction of microRNAome deregulation in rat liver by long-term tamoxifen exposure
-
Pogribny IP, Tryndyak VP, Boyko A, Rodriguez-Juarez R, Beland FA, Kovalchuk O. 2007. Induction of microRNAome deregulation in rat liver by long-term tamoxifen exposure. Mutat. Res. 619:30-37
-
(2007)
Mutat. Res
, vol.619
, pp. 30-37
-
-
Pogribny, I.P.1
Tryndyak, V.P.2
Boyko, A.3
Rodriguez-Juarez, R.4
Beland, F.A.5
Kovalchuk, O.6
-
100
-
-
33646157967
-
Comprehensive analysis of microRNA expression patterns in hepatocellular carcinoma and non-tumorous tissues
-
Murakami T, Yasuda T, Saigo K, Urashima T, Toyoda H, et al. 2006. Comprehensive analysis of microRNA expression patterns in hepatocellular carcinoma and non-tumorous tissues. Oncogene 25:2537-45
-
(2006)
Oncogene
, vol.25
, pp. 2537-2545
-
-
Murakami, T.1
Yasuda, T.2
Saigo, K.3
Urashima, T.4
Toyoda, H.5
-
101
-
-
60749122411
-
RDX induces aberrant expression microRNAs in mouse brain and liver
-
Zhang B, Pan X. 2009. RDX induces aberrant expression microRNAs in mouse brain and liver. Environ. Health Perspect. 117:231-40
-
(2009)
Environ. Health Perspect
, vol.117
, pp. 231-240
-
-
Zhang, B.1
Pan, X.2
-
102
-
-
82755161786
-
Epigenetic regulation of microRNAs in cancer: An integrated review of literature
-
Kunej T, Godnic I, Ferdin J, Horvat S, Dovc P, Calin GA. 2011. Epigenetic regulation of microRNAs in cancer: an integrated review of literature. Mutat. Res. 717:77-84
-
(2011)
Mutat. Res
, vol.717
, pp. 77-84
-
-
Kunej, T.1
Godnic, I.2
Ferdin, J.3
Horvat, S.4
Dovc, P.5
Calin, G.A.6
-
103
-
-
67649349865
-
MicroRNA-125a-5p partly regulates the inflammatory response, lipid uptake, andORP9 expression in oxLDL-stimulated monocyte/macrophages
-
Chen T, Huang Z, Wang L, Wang Y, Wu F, et al. 2009. MicroRNA-125a-5p partly regulates the inflammatory response, lipid uptake, andORP9 expression in oxLDL-stimulated monocyte/macrophages. Cardiovasc. Res. 83:131-39
-
(2009)
Cardiovasc. Res
, vol.83
, pp. 131-139
-
-
Chen, T.1
Huang, Z.2
Wang, L.3
Wang, Y.4
Wu, F.5
-
104
-
-
77950600443
-
MicroRNA-dependent regulation of DNA methyltransferase-1 and tumor suppressor gene expression by interleukin-6 in human malignant cholangiocytes
-
Braconi C, Huang N, Patel T. 2010. MicroRNA-dependent regulation of DNA methyltransferase-1 and tumor suppressor gene expression by interleukin-6 in human malignant cholangiocytes. Hepatology 51:881-90
-
(2010)
Hepatology
, vol.51
, pp. 881-890
-
-
Braconi, C.1
Huang, N.2
Patel, T.3
-
105
-
-
66949118228
-
Interleukin-6modulates the expression of the bone morphogenic protein receptor type II through a novel STAT3-microRNA cluster 17/92 pathway
-
BrockM, Trenkmann M, Gay RE, Michel BA, Gay S, et al. 2009. Interleukin-6modulates the expression of the bone morphogenic protein receptor type II through a novel STAT3-microRNA cluster 17/92 pathway. Circ. Res. 104:1184-91
-
(2009)
Circ. Res
, vol.104
, pp. 1184-1191
-
-
Brockmtrenkmann, M.1
Gay, R.E.2
Michel, B.A.3
Gay, S.4
-
106
-
-
34548039517
-
Interleukin-6-dependent survival of multiple myeloma cells involves the Stat3-mediated induction of microRNA-21 through a highly conserved enhancer
-
LofflerD, Brocke-Heidrich K, Pfeifer G, Stocsits C, Hackerm uller J, et al. 2007. Interleukin-6-dependent survival of multiple myeloma cells involves the Stat3-mediated induction of microRNA-21 through a highly conserved enhancer. Blood 110:1330-33
-
(2007)
Blood
, vol.110
, pp. 1330-1333
-
-
Loffler, D.1
Brocke-Heidrich, K.2
Pfeifer, G.3
Stocsits, C.4
Hackermuller, J.5
-
107
-
-
71749096218
-
MiR-146a is critical for endotoxin-induced tolerance: Implication in innate immunity
-
Nahid MA, Pauley KM, Satoh M, Chan EK. 2009. miR-146a is critical for endotoxin-induced tolerance: implication in innate immunity. J. Biol. Chem. 284:34590-99
-
(2009)
J. Biol. Chem
, vol.284
, pp. 34590-34599
-
-
Nahid, M.A.1
Pauley, K.M.2
Satoh, M.3
Chan, E.K.4
-
108
-
-
79251592866
-
Mechanistic role of microRNA-146a in endotoxin-induced differential cross-regulation of TLR signaling
-
Nahid MA, Satoh M, Chan EK. 2011. Mechanistic role of microRNA-146a in endotoxin-induced differential cross-regulation of TLR signaling. J. Immunol. 186:1723-34
-
(2011)
J. Immunol
, vol.186
, pp. 1723-1734
-
-
Nahid, M.A.1
Satoh, M.2
Chan, E.K.3
-
109
-
-
79959387361
-
Targeting of microRNA-142-3p in dendritic cells regulates endotoxin-induced mortality
-
Sun Y, Varambally S, Maher CA, Cao Q, Chockley P, et al. 2012. Targeting of microRNA-142-3p in dendritic cells regulates endotoxin-induced mortality. Blood 117:6172-83
-
(2012)
Blood
, vol.117
, pp. 6172-6183
-
-
Sun, Y.1
Varambally, S.2
Maher, C.A.3
Cao, Q.4
Chockley, P.5
-
110
-
-
70349298831
-
Halothane-induced liver injury is mediated by interleukin-17 in mice
-
Kobayashi E, Kobayashi M, Tsuneyama K, Fukami T, Nakajima M, Yokoi T. 2009. Halothane-induced liver injury is mediated by interleukin-17 in mice. Toxicol. Sci. 111:302-10
-
(2009)
Toxicol. Sci
, vol.111
, pp. 302-310
-
-
Kobayashi, E.1
Kobayashi, M.2
Tsuneyama, K.3
Fukami, T.4
Nakajima, M.5
Yokoi, T.6
-
111
-
-
77954817589
-
Interleukin-17 is involved in α-naphthylisothiocyanate-induced liver injury in mice
-
Kobayashi M, Higuchi S, Mizuno K, Tsuneyama K, Fukami T, et al. 2010. Interleukin-17 is involved in α-naphthylisothiocyanate-induced liver injury in mice. Toxicology 275:50-57
-
(2010)
Toxicology
, vol.275
, pp. 50-57
-
-
Kobayashi, M.1
Higuchi, S.2
Mizuno, K.3
Tsuneyama, K.4
Fukami, T.5
-
112
-
-
84857037326
-
Involvement of immunerelated factors in diclofenac-induced acute liver injury in mice
-
Yano A, Higuchi S, Tsuneyama K, Fukami T, Nakajima M, Yokoi T. 2012. Involvement of immunerelated factors in diclofenac-induced acute liver injury in mice. Toxicology 293:107-14
-
(2012)
Toxicology
, vol.293
, pp. 107-114
-
-
Yano, A.1
Higuchi, S.2
Tsuneyama, K.3
Fukami, T.4
Nakajima, M.5
Yokoi, T.6
-
113
-
-
0027443904
-
Cytokines down-regulate expression of major cytochrome P-450 enzymes in adult human hepatocytes in primary culture
-
Abdel-Razzak Z, Loyer P, Fautrel A, Gautier JC, Corcos L, et al. 1993. Cytokines down-regulate expression of major cytochrome P-450 enzymes in adult human hepatocytes in primary culture. Mol. Pharmacol. 44:707-15
-
(1993)
Mol. Pharmacol
, vol.44
, pp. 707-715
-
-
Abdel-Razzak, Z.1
Loyer, P.2
Fautrel, A.3
Gautier, J.C.4
Corcos, L.5
-
114
-
-
0034637122
-
Interleukin-6 negatively regulates the expression of pregnane X receptor and constitutively activated receptor in primary human hepatocytes
-
Pascussi JM, Gerbal-Chaloin S, Pichard-Garcia L, Daujat M, Fabre JM, et al. 2000. Interleukin-6 negatively regulates the expression of pregnane X receptor and constitutively activated receptor in primary human hepatocytes. Biochem. Biophys. Res. Commun. 274:707-13
-
(2000)
Biochem. Biophys. Res. Commun
, vol.274
, pp. 707-713
-
-
Pascussi, J.M.1
Gerbal-Chaloin, S.2
Pichard-Garcia, L.3
Daujat, M.4
Fabre, J.M.5
-
115
-
-
84865817146
-
Involvement of Th2 cytokines in the mouse model of flutamide-induced liver injury
-
Higuchi S, Kobayashi M, Yano A, Tsuneyama K, Fukami T, et al. 2012. Involvement of Th2 cytokines in the mouse model of flutamide-induced liver injury. J. Appl. Toxicol. 32:815-22
-
(2012)
J. Appl. Toxicol
, vol.32
, pp. 815-822
-
-
Higuchi, S.1
Kobayashi, M.2
Yano, A.3
Tsuneyama, K.4
Fukami, T.5
-
116
-
-
78651090716
-
IL-4 mediates dicloxacillininduced liver injury in mice
-
Higuchi S, Kobayashi M, Yoshikawa Y, Tsuneyama K, Fukami T, et al. 2011. IL-4 mediates dicloxacillininduced liver injury in mice. Toxicol. Lett. 200:139-45
-
(2011)
Toxicol. Lett
, vol.200
, pp. 139-145
-
-
Higuchi, S.1
Kobayashi, M.2
Yoshikawa, Y.3
Tsuneyama, K.4
Fukami, T.5
-
117
-
-
0037447974
-
SNP and haplotype variation in the human genome
-
Salisbury BA, Pungliya M, Choi JY, Jiang R, Sun XJ, Stephens JC. 2003. SNP and haplotype variation in the human genome. Mutat. Res. 526:53-61
-
(2003)
Mutat. Res
, vol.526
, pp. 53-61
-
-
Salisbury, B.A.1
Pungliya, M.2
Choi, J.Y.3
Jiang, R.4
Sun, X.J.5
Stephens, J.C.6
-
119
-
-
34447319406
-
Single nucleotide polymorphism associated with mature miR-125a alters the processing of pri-miRNA
-
Duan R, Pak C, Jin P. 2007. Single nucleotide polymorphism associated with mature miR-125a alters the processing of pri-miRNA. Hum. Mol. Genet. 16:1124-31
-
(2007)
Hum. Mol. Genet
, vol.16
, pp. 1124-1131
-
-
Duan, R.1
Pak, C.2
Jin, P.3
-
120
-
-
33847665108
-
Human polymorphism at microRNAs and microRNA target sites
-
Saunders MA, Liang H, Li WH. 2007. Human polymorphism at microRNAs and microRNA target sites. Proc. Natl. Acad. Sci. USA 104:3300-5
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 3300-3305
-
-
Saunders Ma Liang, H.1
Li, W.H.2
-
121
-
-
81755163596
-
Role of primary miRNA polymorphic variants in metastatic colon cancer patients treated with 5-fluorouracil and irinotecan
-
Boni V, Zarate R, Bandres E, Gomez MA, Maiello E, et al. 2011. Role of primary miRNA polymorphic variants in metastatic colon cancer patients treated with 5-fluorouracil and irinotecan. Pharmacogenomics J. 11:429-36
-
(2011)
Pharmacogenomics J
, vol.11
, pp. 429-436
-
-
Boni, V.1
Zarate, R.2
Bandres, E.3
Gomez, M.A.4
Maiello, E.5
-
122
-
-
52949119537
-
MicroRNA target site polymorphisms and human disease
-
Sethupathy P, Collins FS. 2008. MicroRNA target site polymorphisms and human disease. Trends Genet. 24:489-97
-
(2008)
Trends Genet
, vol.24
, pp. 489-497
-
-
Sethupathy, P.1
Collins, F.S.2
-
123
-
-
65649138698
-
MicroRNA polymorphisms: The future of pharmacogenomics, molecular epidemiology and individualized medicine
-
Mishra PJ, Bertino JR. 2009. MicroRNA polymorphisms: the future of pharmacogenomics, molecular epidemiology and individualized medicine. Pharmacogenomics 10:399-416
-
(2009)
Pharmacogenomics
, vol.10
, pp. 399-416
-
-
Mishra, P.J.1
Bertino, J.R.2
-
124
-
-
78549246589
-
Functional genetic variants in the 3′-untranslated region of sulfotransferase isoform 1A1 (SULT1A1) and their effect on enzymatic activity
-
Yu X, Dhakal IB, Beggs M, Edavana VK, Williams S, et al. 2010. Functional genetic variants in the 3′-untranslated region of sulfotransferase isoform 1A1 (SULT1A1) and their effect on enzymatic activity. Toxicol. Sci. 118:391-403
-
(2010)
Toxicol. Sci
, vol.118
, pp. 391-403
-
-
Yu, X.1
Dhakal, I.B.2
Beggs, M.3
Edavana, V.K.4
Williams, S.5
-
125
-
-
80053901650
-
A genome-wide survey for SNPs altering microRNA seed sites identifies functional candidates in GWAS
-
Richardson K, Lai CQ, Parnell LD, Lee YC, Ordovas JM. 2011. A genome-wide survey for SNPs altering microRNA seed sites identifies functional candidates in GWAS. BMC Genomics 12:504
-
(2011)
BMC Genomics
, vol.12
, pp. 504
-
-
Richardson, K.1
Lai, C.Q.2
Parnell, L.D.3
Lee, Y.C.4
Ordovas, J.M.5
-
126
-
-
34548059198
-
A miR-24 microRNA binding-site polymorphism in dihydrofolate reductase gene leads tomethotrexate resistance
-
Mishra PJ, Humeniuk R, Mishra PJ, Longo-Sorbello GA, Banerjee D, Bertino JR. 2007. A miR-24 microRNA binding-site polymorphism in dihydrofolate reductase gene leads tomethotrexate resistance. Proc. Natl. Acad. Sci. USA 104:13513-18
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 13513-13518
-
-
Mishra, P.J.1
Humeniuk, R.2
Mishra, P.J.3
Longo-Sorbello, G.A.4
Banerjee, D.5
Bertino, J.R.6
-
127
-
-
79957633053
-
Differential allelic expression of c.1568C A at UGT2B15 is due to variation in a novel cis-regulatory element in the 3-UTR
-
Sun C, Southard C, Olopade OI, Di Rienzo AD. 2011. Differential allelic expression of c.1568C A at UGT2B15 is due to variation in a novel cis-regulatory element in the 3-UTR. Gene 481:24-28
-
(2011)
Gene
, vol.481
, pp. 24-28
-
-
Sun, C.1
Southard, C.2
Olopade, O.I.3
Di Rienzo, A.D.4
-
128
-
-
0034724324
-
Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo
-
Hoffmeyer S, Burk O, von Richter O, Arnold HP, Brockm oller J, et al. 2000. Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo. Proc. Natl. Acad. Sci. USA 97:3473-78
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 3473-3478
-
-
Hoffmeyer, S.1
Burk, O.2
Von Richter, O.3
Arnold, H.P.4
Brockm Oller, J.5
-
129
-
-
43449102192
-
Detection of elevated levels of tumor-associated microRNAs in serum of patients with diffuse large B-cell lymphoma
-
Lawrie CH, Gal S, Dunlop HM, Pushkaran B, Liggins AP, et al. 2008. Detection of elevated levels of tumor-associated microRNAs in serum of patients with diffuse large B-cell lymphoma. Br. J. Haematol. 141:672-75
-
(2008)
Br. J. Haematol
, vol.141
, pp. 672-675
-
-
Lawrie, C.H.1
Gal, S.2
Dunlop, H.M.3
Pushkaran, B.4
Liggins, A.P.5
-
130
-
-
82755187564
-
Extracellular microRNA: A new source of biomarkers
-
Etheridge A, Lee I, Hood L, Galas D, Wang K. 2011. Extracellular microRNA: a new source of biomarkers. Mutat. Res. 717:85-90
-
(2011)
Mutat. Res
, vol.717
, pp. 85-90
-
-
Etheridge, A.1
Lee, I.2
Hood, L.3
Galas, D.4
Wang, K.5
-
131
-
-
63149121152
-
Circulating microRNAs, potential biomarkers for drug-induced liver injury
-
Wang K, Zhang S, Marzolf B, Troisch P, Brightman A, et al. 2009. Circulating microRNAs, potential biomarkers for drug-induced liver injury. Proc. Natl. Acad. Sci. USA 106:4402-7
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 4402-4407
-
-
Wang, K.1
Zhang, S.2
Marzolf, B.3
Troisch, P.4
Brightman, A.5
-
132
-
-
70449709341
-
Plasma microRNAs as sensitive and specific biomarkers of tissue injury
-
Laterza OF, Lim L, Garrett-Engele PW, Vlasakova K, Muniappa N, et al. 2009. Plasma microRNAs as sensitive and specific biomarkers of tissue injury. Clin. Chem. 55:1977-83
-
(2009)
Clin. Chem
, vol.55
, pp. 1977-1983
-
-
Laterza, O.F.1
Lim, L.2
Garrett-Engele, P.W.3
Vlasakova, K.4
Muniappa, N.5
-
133
-
-
78649837734
-
Plasma microRNA-122 as a biomarker for viral-, alcohol-, and chemical-related hepatic diseases
-
Zhang Y, Jia Y, Zheng R, Guo Y, Wang Y, et al. 2010. Plasma microRNA-122 as a biomarker for viral-, alcohol-, and chemical-related hepatic diseases. Clin. Chem. 56:1830-38
-
(2010)
Clin. Chem
, vol.56
, pp. 1830-1838
-
-
Zhang, Y.1
Jia, Y.2
Zheng, R.3
Guo, Y.4
Wang, Y.5
-
134
-
-
84857166172
-
Plasma microRNA profiles in rat models of hepatocellular injury, cholestasis, and steatosis
-
Yamaura Y, NakajimaM, Takagi S, FukamiT, Tsuneyama K, Yokoi T. 2012. Plasma microRNA profiles in rat models of hepatocellular injury, cholestasis, and steatosis. PLoS ONE 7:e30250
-
(2012)
PLoS ONE
, vol.7
-
-
Yamaura, Y.1
Nakajima, M.2
Takagi, S.3
Fukami, T.4
Tsuneyama, K.5
Yokoi, T.6
-
135
-
-
84862954550
-
Identification of urinary microRNA profiles in rats that may diagnose hepatotoxicity
-
Yang X, Greenhaw J, Shi Q, Su Z, Qian F, et al. 2012. Identification of urinary microRNA profiles in rats that may diagnose hepatotoxicity. Toxicol. Sci. 125:335-44
-
(2012)
Toxicol. Sci
, vol.125
, pp. 335-344
-
-
Yang, X.1
Greenhaw, J.2
Shi, Q.3
Su, Z.4
Qian, F.5
-
136
-
-
80055038826
-
Circulating microRNAs as potential markers of human drug-induced liver injury
-
Starkey Lewis PJ, Dear J, Platt V, Simpson KJ, Craig DGN, et al. 2011. Circulating microRNAs as potential markers of human drug-induced liver injury. Hepatology 54:1767-76
-
(2011)
Hepatology
, vol.54
, pp. 1767-1776
-
-
Starkey Lewis, P.J.1
Dear, J.2
Platt, V.3
Simpson, K.J.4
Craig, D.G.N.5
-
137
-
-
66449105070
-
MicroRNA 18 and 124a down-regulate the glucocorticoid receptor: Implications for glucocorticoid responsiveness in the brain
-
Vreugdenhil E, Verissimo CS, Mariman R, Kamphorst JT, Barbosa JS, et al. 2009. MicroRNA 18 and 124a down-regulate the glucocorticoid receptor: implications for glucocorticoid responsiveness in the brain. Endocrinology 150:2220-28
-
(2009)
Endocrinology
, vol.150
, pp. 2220-2228
-
-
Vreugdenhil, E.1
Verissimo, C.S.2
Mariman, R.3
Kamphorst, J.T.4
Barbosa, J.S.5
-
138
-
-
80052570740
-
MiR-28 regulates Nrf2 expression through a Keap1-independent mechanism
-
Yang M, Yao Y, Eades G, Zhang Y, Zhou Q. 2011. miR-28 regulates Nrf2 expression through a Keap1-independent mechanism. Breast Cancer Res. Treat. 129:983-91
-
(2011)
Breast Cancer Res. Treat
, vol.129
, pp. 983-991
-
-
Yang, M.1
Yao, Y.2
Eades, G.3
Zhang, Y.4
Zhou, Q.5
-
139
-
-
81755171451
-
MiR-200a regulates Nrf2 activation by targeting Keap1 mRNA in breast cancer cells
-
Eades G, Yang M, Yao Y, Zhang Y, Zhou Q. 2011. miR-200a regulates Nrf2 activation by targeting Keap1 mRNA in breast cancer cells. J. Biol. Chem. 286:40725-33
-
(2011)
J. Biol. Chem
, vol.286
, pp. 40725-40733
-
-
Eades, G.1
Yang, M.2
Yao, Y.3
Zhang, Y.4
Zhou, Q.5
|