메뉴 건너뛰기




Volumn 53, Issue , 2013, Pages 377-400

MicroRNAs as mediators of drug toxicity

Author keywords

P450; polymorphism; posttranscriptional regulation; toxicology; transcriptional factor

Indexed keywords

AROMATIC HYDROCARBON RECEPTOR; CELL NUCLEUS RECEPTOR; CYTOCHROME P450 1B1; CYTOCHROME P450 2E1; CYTOCHROME P450 3A4; DICLOXACILLIN; DRUG METABOLIZING ENZYME; ESTROGEN RECEPTOR ALPHA; FLUOROURACIL; FLUTAMIDE; GENOMIC DNA; GLUCOCORTICOID RECEPTOR; HEPATOCYTE NUCLEAR FACTOR 4ALPHA; IRINOTECAN; MICRORNA; MUTAGENIC AGENT; PARACETAMOL; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PREGNANE X RECEPTOR; RETINOID X RECEPTOR; UNTRANSLATED RNA; VITAMIN D RECEPTOR;

EID: 84872259086     PISSN: 03621642     EISSN: 15454304     Source Type: Book Series    
DOI: 10.1146/annurev-pharmtox-011112-140250     Document Type: Review
Times cited : (101)

References (139)
  • 2
  • 3
  • 4
    • 33748928159 scopus 로고    scopus 로고
    • The diverse functions of microRNAs in animal development and disease
    • Kloosterman WP, Plasterk RH. 2006. The diverse functions of microRNAs in animal development and disease. Dev. Cell 11:441-50
    • (2006) Dev. Cell , vol.11 , pp. 441-450
    • Kloosterman, W.P.1    Plasterk, R.H.2
  • 5
    • 77955902024 scopus 로고    scopus 로고
    • The widespread regulation of microRNA biogenesis, function and decay
    • Krol J, Loedige I, Filipowicz W. 2010. The widespread regulation of microRNA biogenesis, function and decay. Nat. Rev. Genet. 11:597-610
    • (2010) Nat. Rev. Genet , vol.11 , pp. 597-610
    • Krol, J.1    Loedige, I.2    Filipowicz, W.3
  • 6
    • 77953629046 scopus 로고    scopus 로고
    • Regulation of mRNA translation and stability by microRNAs
    • Fabian MR, Sonenberg N, Filipowicz W. 2010. Regulation of mRNA translation and stability by microRNAs. Annu. Rev. Biochem. 79:351-79
    • (2010) Annu. Rev. Biochem , vol.79 , pp. 351-379
    • Fabian, M.R.1    Sonenberg, N.2    Filipowicz, W.3
  • 7
    • 66049133419 scopus 로고    scopus 로고
    • Mechanism of miRNA-mediated post-transcriptional regulation in animal cells
    • Chekulaeva M, Filipowicz W. 2009. Mechanism of miRNA-mediated post-transcriptional regulation in animal cells. Curr. Opin. Cell Biol. 21:452-60
    • (2009) Curr. Opin. Cell Biol , vol.21 , pp. 452-460
    • Chekulaeva, M.1    Filipowicz, W.2
  • 9
    • 0027495519 scopus 로고
    • The human phenolsulphotransferase polymorphism is determined by the level of expression of the enzyme protein
    • Jones AL, Roberts RC, Coughtrie MW. 1993. The human phenolsulphotransferase polymorphism is determined by the level of expression of the enzyme protein. Biochem. J. 296:287-90
    • (1993) Biochem. J , vol.296 , pp. 287-290
    • Jones, A.L.1    Roberts, R.C.2    Coughtrie, M.W.3
  • 13
    • 13944282215 scopus 로고    scopus 로고
    • Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs
    • Lim LP, Lau NC, Garrett-Engele P, Grimson A, Schelter JM, et al. 2005. Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature 433:769-73
    • (2005) Nature , vol.433 , pp. 769-773
    • Lim, L.P.1    Lau, N.C.2    Garrett-Engele, P.3    Grimson, A.4    Schelter, J.M.5
  • 14
    • 67749132423 scopus 로고    scopus 로고
    • Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps
    • Chi SW, Zang JB, Mele A, Darnell RB. 2009. Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps. Nature 460:479-86
    • (2009) Nature , vol.460 , pp. 479-486
    • Chi, S.W.1    Zang, J.B.2    Mele, A.3    Darnell, R.B.4
  • 15
    • 0028276386 scopus 로고
    • Complete cDNA sequence of a human dioxin-inducible mRNA identifies a new gene subfamily of cytochrome P450 that maps to chromosome 2
    • Sutter TR, Tang YM, Hayes CL, Wo YY, Jabs EW, et al. 1994. Complete cDNA sequence of a human dioxin-inducible mRNA identifies a new gene subfamily of cytochrome P450 that maps to chromosome 2. J. Biol. Chem. 269:13092-99
    • (1994) J. Biol. Chem , vol.269 , pp. 13092-13099
    • Sutter, T.R.1    Tang, Y.M.2    Hayes, C.L.3    Wo, Y.Y.4    Jabs, E.W.5
  • 16
    • 0030008731 scopus 로고    scopus 로고
    • Activation of chemically diverse procarcinogens by human cytochrome P-450 1B1
    • Shimada T, Hayes CL, Yamazaki H, Amin S, Hecht SS, et al. 1996. Activation of chemically diverse procarcinogens by human cytochrome P-450 1B1. Cancer Res. 56:2979-84
    • (1996) Cancer Res , vol.56 , pp. 2979-2984
    • Shimada, T.1    Hayes, C.L.2    Yamazaki, H.3    Amin, S.4    Hecht, S.S.5
  • 18
  • 19
    • 0028234634 scopus 로고
    • DNA single-strand breaks in kidneys of Syrian hamsters treated with steroidal estrogens: Hormone-induced free radical damage preceding renal malignancy
    • Han X, Liehr JG. 1994. DNA single-strand breaks in kidneys of Syrian hamsters treated with steroidal estrogens: hormone-induced free radical damage preceding renal malignancy. Carcinogenesis 15:997-1000
    • (1994) Carcinogenesis , vol.15 , pp. 997-1000
    • Han, X.1    Liehr, J.G.2
  • 20
    • 0034650264 scopus 로고    scopus 로고
    • Induction of uterine adenocarcinoma inCD-1mice by catechol estrogens
    • Newbold RR, Liehr JG. 2000. Induction of uterine adenocarcinoma inCD-1mice by catechol estrogens. Cancer Res. 60:235-37
    • (2000) Cancer Res , vol.60 , pp. 235-237
    • Newbold, R.R.1    Liehr, J.G.2
  • 23
    • 33749487425 scopus 로고    scopus 로고
    • MicroRNA regulates the expression of human cytochrome P450 1B1
    • Tsuchiya Y, Nakajima M, Takagi S, Taniya T, Yokoi T. 2006. MicroRNA regulates the expression of human cytochrome P450 1B1. Cancer Res. 66:9090-98
    • (2006) Cancer Res , vol.66 , pp. 9090-9098
    • Tsuchiya, Y.1    Nakajima, M.2    Takagi, S.3    Taniya, T.4    Yokoi, T.5
  • 25
    • 39149123560 scopus 로고    scopus 로고
    • CYP2E1 and oxidative liver injury by alcohol
    • Lu Y, Cederbaum AI. 2008. CYP2E1 and oxidative liver injury by alcohol. Free Radic. Biol.Med. 44:723-38
    • (2008) Free Radic. Biol.Med , vol.44 , pp. 723-738
    • Lu, Y.1    Cederbaum, A.I.2
  • 26
    • 0037938645 scopus 로고    scopus 로고
    • The cytochrome P-450 isoenzyme CYP2E1 in the biological processing of industrial chemicals: Consequences for occupational and environmental medicine
    • Bolt HM, Roos PH, Thier R. 2003. The cytochrome P-450 isoenzyme CYP2E1 in the biological processing of industrial chemicals: consequences for occupational and environmental medicine. Int. Arch. Occup. Environ. Health 76:174-85
    • (2003) Int. Arch. Occup. Environ. Health , vol.76 , pp. 174-185
    • Bolt, H.M.1    Roos, P.H.2    Thier, R.3
  • 27
    • 34547899883 scopus 로고    scopus 로고
    • Reverse transcriptase-PCR quantification of mRNA levels from cytochrome (CYP)1, CYP2 and CYP3 families in 22 different human tissues
    • Bìeche I, Narjoz C, Asselah T, Vacher S, Marcellin P, et al. 2007. Reverse transcriptase-PCR quantification of mRNA levels from cytochrome (CYP)1, CYP2 and CYP3 families in 22 different human tissues. Pharmacogenet. Genomics 17:731-42
    • (2007) Pharmacogenet. Genomics , vol.17 , pp. 731-742
    • Bìeche, I.1    Narjoz, C.2    Asselah, T.3    Vacher, S.4    Marcellin, P.5
  • 28
    • 0028237729 scopus 로고
    • Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: Studies with liver microsomes of 30 Japanese and 30 Caucasians
    • Shimada T, Yamazaki H, Mimura M, Inui Y, Guengerich FP. 1994. Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians. J. Pharmacol. Exp. Ther. 270:414-23
    • (1994) J. Pharmacol. Exp. Ther , vol.270 , pp. 414-423
    • Shimada, T.1    Yamazaki, H.2    Mimura, M.3    Inui, Y.4    Guengerich, F.P.5
  • 30
    • 38049103266 scopus 로고    scopus 로고
    • MicroRNA-378 promotes cell survival, tumor growth, and angiogenesis by targeting SuFu and Fs-1 expression
    • Lee DY, Deng Z, Wang CH, Yang BB. 2007. MicroRNA-378 promotes cell survival, tumor growth, and angiogenesis by targeting SuFu and Fs-1 expression. Proc. Natl. Acad. Sci. USA 104:20350-55
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 20350-20355
    • Lee, D.Y.1    Deng, Z.2    Wang, C.H.3    Yang, B.B.4
  • 31
    • 54949154476 scopus 로고    scopus 로고
    • MiRNA-directed regulation of VEGF and other angiogenic factors under hypoxia
    • Hua Z, Lv Q, Ye W, Wong CK, Cai G, et al. 2006. MiRNA-directed regulation of VEGF and other angiogenic factors under hypoxia. PLoS ONE 1:e116
    • (2006) PLoS ONE , vol.1
    • Hua, Z.1    Lv, Q.2    Ye, W.3    Wong, C.K.4    Cai, G.5
  • 32
    • 0024507690 scopus 로고
    • Identification of a novel P450 expressed in rat lung: CDNA cloning and sequence, chromosome mapping, and induction by 3-methylcholanthrene
    • Kimura S, Kozak CA, Gonzalez FJ. 1989. Identification of a novel P450 expressed in rat lung: cDNA cloning and sequence, chromosome mapping, and induction by 3-methylcholanthrene. Biochemistry 28:3798-803
    • (1989) Biochemistry , vol.28 , pp. 3798-3803
    • Kimura, S.1    Kozak, C.A.2    Gonzalez, F.J.3
  • 33
    • 13944282327 scopus 로고    scopus 로고
    • Cytochrome P450 enzymes as catalysts of metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, a tobacco specific carcinogen
    • Jalas JR, Hecht SS, Murphy SE. 2005. Cytochrome P450 enzymes as catalysts of metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, a tobacco specific carcinogen. Chem. Res. Toxicol. 18:95-110
    • (2005) Chem. Res. Toxicol , vol.18 , pp. 95-110
    • Jalas, J.R.1    Hecht, S.S.2    Murphy, S.E.3
  • 34
    • 57349134379 scopus 로고    scopus 로고
    • Differential expression of microRNAs in earlystage neoplastic transformation in the lungs of F344 rats chronically treated with the tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone
    • Kalscheuer S, Zhang X, Zeng Y, Upadhyaya P. 2008. Differential expression of microRNAs in earlystage neoplastic transformation in the lungs of F344 rats chronically treated with the tobacco carcinogen 4-(methylnitrosamino)-1-(3- pyridyl)-1-butanone. Carcinogenesis 29:2394-99
    • (2008) Carcinogenesis , vol.29 , pp. 2394-2399
    • Kalscheuer, S.1    Zhang, X.2    Zeng, Y.3    Upadhyaya, P.4
  • 35
    • 34548803950 scopus 로고    scopus 로고
    • MicroRNA-34b and microRNA-34c are targets of p53 and cooperate in control of cell proliferation and adhesion-independent growth
    • Corney DC, Flesken-Nikitin A, Godwin AK, WangW, Nikitin AY. 2007. microRNA-34b and microRNA-34c are targets of p53 and cooperate in control of cell proliferation and adhesion-independent growth. Cancer Res. 67:8433-38
    • (2007) Cancer Res , vol.67 , pp. 8433-8438
    • Corney, D.C.1    Flesken-Nikitin, A.2    Godwin, A.K.3    Wang, W.4    Nikitin, A.Y.5
  • 36
    • 34250851115 scopus 로고    scopus 로고
    • A microRNA component of the p53 tumour suppressor network
    • He L, He X, Lim LP, de Stanchina E, Xuan Z, et al. 2007. A microRNA component of the p53 tumour suppressor network. Nature 447:1130-34
    • (2007) Nature , vol.447 , pp. 1130-1134
    • He, L.1    He, X.2    Lim, L.3    Pde Stanchina, E.4    Xuan, Z.5
  • 37
    • 0030935086 scopus 로고    scopus 로고
    • Use of in vitro and in vivo data to estimate the likelihood of metabolic pharmacokinetic interactions
    • Bertz RJ, Granneman GR. 1997. Use of in vitro and in vivo data to estimate the likelihood of metabolic pharmacokinetic interactions. Clin. Pharmacokinet. 32:210-58
    • (1997) Clin. Pharmacokinet , vol.32 , pp. 210-258
    • Bertz, R.J.1    Granneman, G.R.2
  • 38
    • 0025094496 scopus 로고
    • Evidence for involvement of multiple forms of cytochrome P-450 in aflatoxin B1 metabolism in human liver
    • Forrester LM, Neal GE, Judah DJ, Glancey MJ, Wolf CR. 1990. Evidence for involvement of multiple forms of cytochrome P-450 in aflatoxin B1 metabolism in human liver. Proc.Natl. Acad. Sci. USA87:8306-10
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 8306-8310
    • Forrester, L.M.1    Neal, G.E.2    Judah, D.J.3    Glancey, M.J.4    Wolf, C.R.5
  • 39
    • 0024326433 scopus 로고
    • Role of individual human cytochrome P-450 enzymes in the bioactivation of benzo(a)pyrene 7, 8-dihydroxy-7, 8-dihydrobenzo(a)pyrene, and other dihydrodiol derivatives of polycyclic aromatic hydrocarbons
    • Shimada T, Martin MV, Pruess-Schwartz D, Marnett LJ, Guengerich FP. 1989. Role of individual human cytochrome P-450 enzymes in the bioactivation of benzo(a)pyrene, 7, 8-dihydroxy-7, 8-dihydrobenzo(a)pyrene, and other dihydrodiol derivatives of polycyclic aromatic hydrocarbons. Cancer Res. 49:6304-12
    • (1989) Cancer Res , vol.49 , pp. 6304-6312
    • Shimada, T.1    Martin, M.V.2    Pruess-Schwartz, D.3    Marnett, L.J.4    Guengerich, F.P.5
  • 40
    • 0036089341 scopus 로고    scopus 로고
    • Co-regulation of CYP3A4 and CYP3A5 and contribution to hepatic and intestinal midazolam metabolism
    • Lin YS, Dowling AL, Quigley SD, Farin FM, Zhang J, et al. 2002. Co-regulation of CYP3A4 and CYP3A5 and contribution to hepatic and intestinal midazolam metabolism. Mol. Pharmacol. 62:162-72
    • (2002) Mol. Pharmacol , vol.62 , pp. 162-172
    • Lin, Y.S.1    Dowling, A.L.2    Quigley, S.D.3    Farin, F.M.4    Zhang, J.5
  • 41
    • 0142250945 scopus 로고    scopus 로고
    • Genotype-phenotype associations for common CYP3A4 and CYP3A5 variants in the basal and induced metabolism of midazolam in European-and African-American men and women
    • Floyd MD, Gervasini G, Masica AL, Mayo G, George AL Jr, et al. 2003. Genotype-phenotype associations for common CYP3A4 and CYP3A5 variants in the basal and induced metabolism of midazolam in European-and African-American men and women. Pharmacogenetics 13:596-606
    • (2003) Pharmacogenetics , vol.13 , pp. 596-606
    • Floyd, M.D.1    Gervasini, G.2    Masica, A.L.3    Mayo, G.4    George Jr., A.L.5
  • 43
    • 0036219998 scopus 로고    scopus 로고
    • Common allelic variants of cytochrome P4503A4 and their prevalence in different populations
    • Lamba JK, Lin YS, ThummelK, Daly A, Watkins PB, et al. 2002. Common allelic variants of cytochrome P4503A4 and their prevalence in different populations. Pharmacogenetics 12:121-32
    • (2002) Pharmacogenetics , vol.12 , pp. 121-132
    • Lamba, J.K.1    Lin, Y.S.2    Thummel, K.3    Daly, A.4    Watkins, P.B.5
  • 45
    • 44349182094 scopus 로고    scopus 로고
    • Post-transcriptional regulation of human pregnane X receptor by microRNA affects the expression of cytochrome P450 3A4
    • Takagi S, Nakajima M, Mohri T, Yokoi T. 2008. Post-transcriptional regulation of human pregnane X receptor by microRNA affects the expression of cytochrome P450 3A4. J. Biol. Chem. 283:9674-80
    • (2008) J. Biol. Chem , vol.283 , pp. 9674-9680
    • Takagi, S.1    Nakajima, M.2    Mohri, T.3    Yokoi, T.4
  • 46
    • 70349268327 scopus 로고    scopus 로고
    • MicroRNAs regulateCYP3A4 expression via direct and indirect targeting
    • PanYZ, GaoW, YuAM.2009. MicroRNAs regulateCYP3A4 expression via direct and indirect targeting. Drug Metab. Dispos. 37:2112-17
    • (2009) Drug Metab. Dispos , vol.37 , pp. 2112-2117
    • Pan, Y.Z.1    Gao, W.2    Yu, A.M.3
  • 47
    • 23744437421 scopus 로고    scopus 로고
    • Noncalcemic actions of vitamin Dreceptor ligands
    • Nagpal S, Na S, Rathnachalam R. 2005. Noncalcemic actions of vitamin Dreceptor ligands. Endocr. Rev. 26:662-87
    • (2005) Endocr. Rev , vol.26 , pp. 662-687
    • Nagpal, S.1    Na, S.2    Rathnachalam, R.3
  • 48
    • 34548202165 scopus 로고    scopus 로고
    • Vitamin D signaling pathways in cancer: Potential for anticancer therapeutics
    • Deeb KK, Trump DL, Johnson CS. 2007. Vitamin D signaling pathways in cancer: potential for anticancer therapeutics. Nat. Rev. Cancer 7:684-700
    • (2007) Nat. Rev. Cancer , vol.7 , pp. 684-700
    • Deeb, K.K.1    Trump, D.L.2    Johnson, C.S.3
  • 49
    • 33845291140 scopus 로고    scopus 로고
    • Novel patterns of genome rearrangement and their association with survival in breast cancer
    • Hicks J, KrasnitzA, Lakshmi B, Navin NE, Riggs M, et al. 2006. Novel patterns of genome rearrangement and their association with survival in breast cancer. Genome Res. 16:1465-79
    • (2006) Genome Res , vol.16 , pp. 1465-1479
    • Hicks, J.1    Krasnitz, A.2    Lakshmi, B.3    Navin, N.E.4    Riggs, M.5
  • 50
    • 33746822914 scopus 로고    scopus 로고
    • 25(OH)D3 and 1, 25(OH)2D3 serum concentration and breast tissue expression of 1α-hydroxylase, 24-hydroxylase and Vitamin D receptor in women with and without breast cancer
    • de Lyra EC, de Silva IA, Katayama ML, Brentani MM, Nonogaki S, et al. 2006. 25(OH)D3 and 1, 25(OH)2D3 serum concentration and breast tissue expression of 1α-hydroxylase, 24-hydroxylase and Vitamin D receptor in women with and without breast cancer. J. Steroid Biochem. Mol. Biol. 100:184-92
    • (2006) J. Steroid Biochem. Mol. Biol , vol.100 , pp. 184-192
    • De Lyra, E.1    Cde Silva, I.A.2    Katayama, M.L.3    Brentani, M.M.4    Nonogaki, S.5
  • 52
    • 34447514029 scopus 로고    scopus 로고
    • Vitamin D deficiency
    • Holick MF. 2007. Vitamin D deficiency. N. Engl. J. Med. 357:266-81
    • (2007) N. Engl. J. Med , vol.357 , pp. 266-281
    • Holick, M.F.1
  • 54
  • 55
    • 70349333224 scopus 로고    scopus 로고
    • Human CYP24 catalyzing the inactivation of calcitriol is post-transcriptionally regulated by miR-125b
    • Komagata S, Nakajima M, Takagi S, Mohri T, Taniya T, Yokoi T. 2009. Human CYP24 catalyzing the inactivation of calcitriol is post-transcriptionally regulated by miR-125b. Mol. Pharmacol. 76:702-9
    • (2009) Mol. Pharmacol , vol.76 , pp. 702-709
    • Komagata, S.1    Nakajima, M.2    Takagi, S.3    Mohri, T.4    Taniya, T.5    Yokoi, T.6
  • 57
    • 33144490646 scopus 로고    scopus 로고
    • A microRNA expression signature of human solid tumors defines cancer gene targets
    • Volinia S, Calin GA, Liu CG, Ambs S, Cimmino A, et al. 2006. A microRNA expression signature of human solid tumors defines cancer gene targets. Proc. Natl. Acad. Sci. USA 103:2257-61
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 2257-2261
    • Volinia, S.1    Calin, G.A.2    Liu, C.G.3    Ambs, S.4    Cimmino, A.5
  • 58
    • 42249106086 scopus 로고    scopus 로고
    • Regulation of hepatocyte nuclear factor 4α-mediated transcription
    • Gonzalez FJ. 2008. Regulation of hepatocyte nuclear factor 4α-mediated transcription. Drug Metab. Pharmacokinet. 23:2-7
    • (2008) Drug Metab. Pharmacokinet , vol.23 , pp. 2-7
    • Gonzalez, F.J.1
  • 59
    • 34848824067 scopus 로고    scopus 로고
    • Role of human hepatocyte nuclear factor 4αin the expression of drug-metabolizing enzymes and transporters in human hepatocytes assessed by use of small interfering RNA
    • Kamiyama Y, Matsubara T, Yoshinari K, Nagata K, Kamimura H, Yamazoe Y. 2007. Role of human hepatocyte nuclear factor 4αin the expression of drug-metabolizing enzymes and transporters in human hepatocytes assessed by use of small interfering RNA. Drug Metab. Pharmacokinet. 22:287-98
    • (2007) Drug Metab. Pharmacokinet , vol.22 , pp. 287-298
    • Kamiyama, Y.1    Matsubara, T.2    Yoshinari, K.3    Nagata, K.4    Kamimura, H.5    Yamazoe, Y.6
  • 60
    • 77951157723 scopus 로고    scopus 로고
    • MicroRNAs regulate human hepatocyte nuclear factor 4α, modulating the expression of metabolic enzymes and cell cycle
    • Takagi S, Nakajima M, Kida K, Yamaura Y, Fukami T, Yokoi T. 2010. MicroRNAs regulate human hepatocyte nuclear factor 4α, modulating the expression of metabolic enzymes and cell cycle. J. Biol. Chem. 285:4415-22
    • (2010) J. Biol. Chem , vol.285 , pp. 4415-4422
    • Takagi, S.1    Nakajima, M.2    Kida, K.3    Yamaura, Y.4    Fukami, T.5    Yokoi, T.6
  • 61
    • 33750027681 scopus 로고    scopus 로고
    • Cytochrome P450s and cholesterol homeostasis
    • Pikuleva IA. 2006. Cytochrome P450s and cholesterol homeostasis. Pharmacol. Ther. 112:761-73
    • (2006) Pharmacol. Ther , vol.112 , pp. 761-773
    • Pikuleva, I.A.1
  • 62
    • 0029789568 scopus 로고    scopus 로고
    • Functional interference between hypoxia and dioxin signal transduction pathways: Competition for recruitment of the Arnt transcription factor
    • Gradin K, McGuire J, Wenger RH, Kvietikova I, Whitelaw ML, et al. 1996. Functional interference between hypoxia and dioxin signal transduction pathways: competition for recruitment of the Arnt transcription factor. Mol. Cell. Biol. 16:5221-31
    • (1996) Mol. Cell. Biol , vol.16 , pp. 5221-5231
    • Gradin, K.1    McGuire, J.2    Wenger, R.H.3    Kvietikova, I.4    Whitelaw, M.L.5
  • 63
    • 33751162428 scopus 로고    scopus 로고
    • Curcumin inhibits hypoxia-inducible factor-1 by degrading aryl hydrocarbon receptor nuclear translocator: A mechanism of tumor growth inhibition
    • Choi H, Chun YS, Kim SW, Kim MS, Park JW. 2006. Curcumin inhibits hypoxia-inducible factor-1 by degrading aryl hydrocarbon receptor nuclear translocator: a mechanism of tumor growth inhibition. Mol. Pharmacol. 70:1664-71
    • (2006) Mol. Pharmacol , vol.70 , pp. 1664-1671
    • Choi, H.1    Chun, Y.S.2    Kim, S.W.3    Kim, M.S.4    Park, J.W.5
  • 64
    • 57349185988 scopus 로고    scopus 로고
    • Curcumin attenuates cytochrome P450 induction in response to 2,3,7, 8-tetrachlorodibenzo-p-dioxin by ROS-dependently degrading AhR and ARNT
    • Choi H, Chun YS, Shin YJ, Ye SK, Kim MS, Park JW. 2008. Curcumin attenuates cytochrome P450 induction in response to 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin by ROS-dependently degrading AhR and ARNT. Cancer Sci. 99:2518-24
    • (2008) Cancer Sci , vol.99 , pp. 2518-2524
    • Choi, H.1    Chun, Y.S.2    Shin, Y.J.3    Ye, S.K.4    Kim, M.S.5    Park, J.W.6
  • 65
    • 84859976379 scopus 로고    scopus 로고
    • Aryl hydrocarbon nuclear translocator in human liver is regulated by miR-24
    • Oda Y, NakajimaM, Mohri T, Takamiya M, Aoki Y, et al. 2012. Aryl hydrocarbon nuclear translocator in human liver is regulated by miR-24. Toxicol. Appl. Pharmacol. 260:222-31
    • (2012) Toxicol. Appl. Pharmacol , vol.260 , pp. 222-231
    • Oda, Y.1    Nakajima, M.2    Mohri, T.3    Takamiya, M.4    Aoki, Y.5
  • 66
    • 34250843675 scopus 로고    scopus 로고
    • The micro-ribonucleic acid (miRNA) miR-206 targets the human estrogen receptor-α(ERα) and represses ERαmessenger RNA and protein expression in breast cancer cell lines
    • Adams BD, Furneaux H, White BA. 2007. The micro-ribonucleic acid (miRNA) miR-206 targets the human estrogen receptor-α(ERα) and represses ERαmessenger RNA and protein expression in breast cancer cell lines. Mol. Endocrinol. 21:1132-47
    • (2007) Mol. Endocrinol , vol.21 , pp. 1132-1147
    • Adams, B.D.1    Furneaux, H.2    White, B.A.3
  • 67
    • 57649174634 scopus 로고    scopus 로고
    • MicroRNA-221/222 negatively regulates estrogen receptor αand is associated with tamoxifen resistance in breast cancer
    • Zhao JJ, Lin J, Yang H, Kong W, He L, et al. 2008. MicroRNA-221/222 negatively regulates estrogen receptor αand is associated with tamoxifen resistance in breast cancer. J. Biol. Chem. 283:31079-86
    • (2008) J. Biol. Chem , vol.283 , pp. 31079-31086
    • Zhao, J.J.1    Lin, J.2    Yang, H.3    Kong, W.4    He, L.5
  • 68
    • 77949617195 scopus 로고    scopus 로고
    • An estrogen receptor αsuppressor, microRNA-22, is downregulated in estrogen receptor α-positive human breast cancer cell lines and clinical samples
    • Xiong J, Yu D, Wei N, Fu H, Cai T, et al. 2010. An estrogen receptor αsuppressor, microRNA-22, is downregulated in estrogen receptor α-positive human breast cancer cell lines and clinical samples. FEBS J. 277:1684-94
    • (2010) FEBS J , vol.277 , pp. 1684-1694
    • Xiong, J.1    Yu, D.2    Wei, N.3    Fu, H.4    Cai, T.5
  • 69
    • 67650135755 scopus 로고    scopus 로고
    • MiR-22 inhibits estrogen signaling by directly targeting the estrogen receptor αmRNA
    • Pandey DP, Picard D. 2009. miR-22 inhibits estrogen signaling by directly targeting the estrogen receptor αmRNA. Mol. Cell. Biol. 29:3783-90
    • (2009) Mol. Cell. Biol , vol.29 , pp. 3783-3790
    • Pandey, D.P.1    Picard, D.2
  • 70
    • 78549249846 scopus 로고    scopus 로고
    • Epigenetically deregulated microRNA-375 is involved in a positive feedback loop with estrogen receptor α in breast cancer cells
    • de Souza Rocha Simonini P, Breiling A, Gupta N, Malekpour M, Youns M, et al. 2010. Epigenetically deregulated microRNA-375 is involved in a positive feedback loop with estrogen receptor α in breast cancer cells. Cancer Res. 70:9175-84
    • (2010) Cancer Res , vol.70 , pp. 9175-9184
    • De Souza Rocha Simonini, P.1    Breiling, A.2    Gupta, N.3    Malekpour, M.4    Youns, M.5
  • 71
    • 77954497664 scopus 로고    scopus 로고
    • MicroRNA-27a indirectly regulates estrogen receptor αexpression and hormone responsiveness inMCF-7 breast cancer cells
    • Li X, Mertens-Talcott SU, Zhang S, Kim K, Ball J, Safe S. 2010. MicroRNA-27a indirectly regulates estrogen receptor αexpression and hormone responsiveness inMCF-7 breast cancer cells. Endocrinology 151:2462-73
    • (2010) Endocrinology , vol.151 , pp. 2462-2473
    • Li, X.1    Mertens-Talcott, S.U.2    Zhang, S.3    Kim, K.4    Ball, J.5    Safe, S.6
  • 72
    • 80054764011 scopus 로고    scopus 로고
    • PPARα is regulated by miR-21 and miR-27b in human liver
    • Kida K, Nakajima M, Mohri T, Oda Y, Takagi S, et al. 2011. PPARα is regulated by miR-21 and miR-27b in human liver. Pharm. Res. 28:2467-76
    • (2011) Pharm. Res , vol.28 , pp. 2467-2476
    • Kida, K.1    Nakajima, M.2    Mohri, T.3    Oda, Y.4    Takagi, S.5
  • 74
    • 77951219696 scopus 로고    scopus 로고
    • MicroRNA-27b contributes to lipopolysaccharide-mediated peroxisome proliferator-activated preceptor γ (PPARγ) mRNA destabilization
    • Jennewein C, von Knethen A, Schmid T, Brune B. 2010. MicroRNA-27b contributes to lipopolysaccharide-mediated peroxisome proliferator-activated preceptor γ (PPARγ) mRNA destabilization. J. Biol. Chem. 285:11846-53
    • (2010) J. Biol. Chem , vol.285 , pp. 11846-11853
    • Jennewein, C.1    Von Knethen, A.2    Schmid, T.3    Brune, B.4
  • 75
    • 76349089521 scopus 로고    scopus 로고
    • MiR-27a is a negative regulator of adipocyte differentiation via suppressing PPARγexpression
    • Kim SY, Kim AY, Lee HW, Son YH, Lee GY, et al. 2010. miR-27a is a negative regulator of adipocyte differentiation via suppressing PPARγexpression. Biochem. Biophys. Res. Commun. 392:323-28
    • (2010) Biochem. Biophys. Res. Commun , vol.392 , pp. 323-328
    • Kim, S.Y.1    Kim, A.Y.2    Lee, H.W.3    Son, Y.H.4    Lee, G.Y.5
  • 76
    • 63049108381 scopus 로고    scopus 로고
    • A role of miR-27 in the regulation of adipogenesis
    • Lin Q, Gao Z, Alarcon RM, Ye J, Yun Z. 2009. A role of miR-27 in the regulation of adipogenesis. FEBS J. 276:2348-58
    • (2009) FEBS J , vol.276 , pp. 2348-2358
    • Lin, Q.1    Gao, Z.2    Alarcon, R.M.3    Ye, J.4    Yun, Z.5
  • 77
    • 59849084351 scopus 로고    scopus 로고
    • Over-expressedmicroRNA-27a and 27b influence fat accumulation and cell proliferation during rat hepatic stellate cell activation
    • Ji J, Zhang J, Huang G, Qian J, Wang X, Mei S. 2009. Over- expressedmicroRNA-27a and 27b influence fat accumulation and cell proliferation during rat hepatic stellate cell activation. FEBS Lett. 583:759-66
    • (2009) FEBS Lett , vol.583 , pp. 759-766
    • Ji, J.1    Zhang, J.2    Huang, G.3    Qian, J.4    Wang, X.5    Mei, S.6
  • 78
    • 0035793045 scopus 로고    scopus 로고
    • Impaired adipogenesis and lipolysis in the mouse upon selective ablation of the retinoid X receptor α mediated by a tamoxifen-inducible chimeric Cre recombinase (Cre-ERT2) in adipocytes
    • Imai T, Jiang M, Chambon P, Metzger D. 2001. Impaired adipogenesis and lipolysis in the mouse upon selective ablation of the retinoid X receptor α mediated by a tamoxifen-inducible chimeric Cre recombinase (Cre-ERT2) in adipocytes. Proc. Natl. Acad. Sci. USA 98:224-28
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 224-228
    • Imai, T.1    Jiang, M.2    Chambon, P.3    Metzger, D.4
  • 80
    • 67649511946 scopus 로고    scopus 로고
    • MicroRNA-222 regulates cell invasion by targeting matrix metalloproteinase 1 (MMP1) andmanganese superoxide dismutase 2 (SOD2) in tongue squamous cell carcinoma cell lines
    • Liu X, Yu J, Jiang L, Wang A, Shi F, et al. 2009. MicroRNA-222 regulates cell invasion by targeting matrix metalloproteinase 1 (MMP1) andmanganese superoxide dismutase 2 (SOD2) in tongue squamous cell carcinoma cell lines. Cancer Genomics Proteomics 6:131-39
    • (2009) Cancer Genomics Proteomics , vol.6 , pp. 131-139
    • Liu, X.1    Yu, J.2    Jiang, L.3    Wang, A.4    Shi, F.5
  • 81
    • 78650982065 scopus 로고    scopus 로고
    • Mir-17 suppresses tumorigenicity of prostate cancer by inhibiting mitochondrial antioxidant enzymes
    • Xu Y, Fang F, Zhang J, Josson S, St. Clair WH, St. Clair DK. 2010. mir-17 suppresses tumorigenicity of prostate cancer by inhibiting mitochondrial antioxidant enzymes. PLoS ONE 12:e14356
    • (2010) PLoS ONE , vol.12
    • Xu, Y.1    Fang, F.2    Zhang, J.3    Josson, S.4    St. Clair, W.H.5    St. Clair, D.K.6
  • 82
    • 48649102010 scopus 로고    scopus 로고
    • Identification of hypoxiainducible factor-1αas a novel target for miR-17-92 microRNA cluster
    • Taguchi A, Yanagisawa K, Tanaka M, Cao K, Matsuyama Y, et al. 2008. Identification of hypoxiainducible factor-1αas a novel target for miR-17-92 microRNA cluster. Cancer Res. 68:5540-45
    • (2008) Cancer Res , vol.68 , pp. 5540-5545
    • Taguchi, A.1    Yanagisawa, K.2    Tanaka, M.3    Cao, K.4    Matsuyama, Y.5
  • 83
    • 34250163202 scopus 로고    scopus 로고
    • Peroxisome proliferatoractivated receptor α regulates a microRNA-mediated signaling cascade responsible for hepatocellular proliferation
    • Shah YM, Morimura K, Yang Q, Tanabe T, Takagi M, Gonzalez FJ. 2007. Peroxisome proliferatoractivated receptor α regulates a microRNA-mediated signaling cascade responsible for hepatocellular proliferation. Mol. Cell. Biol. 27:4238-47
    • (2007) Mol. Cell. Biol , vol.27 , pp. 4238-4247
    • Shah, Y.M.1    Morimura, K.2    Yang, Q.3    Tanabe, T.4    Takagi, M.5    Gonzalez, F.J.6
  • 84
    • 0038367669 scopus 로고    scopus 로고
    • Activation of Nrf2 and accumulation of ubiquitinated A170 by arsenic in osteoblasts
    • Aono J, Yanagawa T, Itoh K, Li B, Yoshida H, et al. 2003. Activation of Nrf2 and accumulation of ubiquitinated A170 by arsenic in osteoblasts. Biochem. Biophys. Res. Commun. 305:271-77
    • (2003) Biochem. Biophys. Res. Commun , vol.305 , pp. 271-277
    • Aono, J.1    Yanagawa, T.2    Itoh, K.3    Li, B.4    Yoshida, H.5
  • 85
    • 33845312687 scopus 로고    scopus 로고
    • MicroRNA responses to cellular stress
    • Marsit CJ, Eddy K, Kelsey KT. 2006. MicroRNA responses to cellular stress. Cancer Res. 66:10843-48
    • (2006) Cancer Res , vol.66 , pp. 10843-10848
    • Marsit, C.J.1    Eddy, K.2    Kelsey, K.T.3
  • 86
    • 35648945351 scopus 로고    scopus 로고
    • Changes of micro-RNA expression in rat liver treated by acetaminophen or carbon tetrachloride: Regulating role of micro-RNA for RNA expression
    • Fukushima T, Hamada Y, Yamada H, Horii I. 2007. Changes of micro-RNA expression in rat liver treated by acetaminophen or carbon tetrachloride: regulating role of micro-RNA for RNA expression. J. Toxicol. Sci. 32:401-9
    • (2007) J. Toxicol. Sci , vol.32 , pp. 401-409
    • Fukushima, T.1    Hamada, Y.2    Yamada, H.3    Horii, I.4
  • 87
    • 82755189770 scopus 로고    scopus 로고
    • Dose-responsiveness and persistence of microRNA expression alterations induced by cigarette smoke in mouse lung
    • Izzotti A, Larghero P, Longobardi M, Cartiglia C, Camoirano A, et al. 2011. Dose-responsiveness and persistence of microRNA expression alterations induced by cigarette smoke in mouse lung. Mutat. Res. 717:9-16
    • (2011) Mutat. Res , vol.717 , pp. 9-16
    • Izzotti, A.1    Larghero, P.2    Longobardi, M.3    Cartiglia, C.4    Camoirano, A.5
  • 88
    • 60549084170 scopus 로고    scopus 로고
    • MicroRNAs as modulators of smoking-induced gene expression changes in human airway epithelium
    • Schembri F, Sridhar S, Perdomo C, Gustafson AM, Zhang X, et al. 2009. MicroRNAs as modulators of smoking-induced gene expression changes in human airway epithelium. Proc. Natl. Acad. Sci. USA 106:2319-24
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 2319-2324
    • Schembri, F.1    Sridhar, S.2    Perdomo, C.3    Gustafson, A.M.4    Zhang, X.5
  • 90
    • 80051699704 scopus 로고    scopus 로고
    • Involvement of microRNAs in dioxin-induced liver damage in the mouse
    • Yoshioka W, Higashiyama W, Tohyama C. 2011. Involvement of microRNAs in dioxin-induced liver damage in the mouse. Toxicol. Sci. 122:457-65
    • (2011) Toxicol. Sci , vol.122 , pp. 457-465
    • Yoshioka, W.1    Higashiyama, W.2    Tohyama, C.3
  • 91
    • 79957756390 scopus 로고    scopus 로고
    • Lack of change in microRNA expression in adult mouse liver following treatment with benzo(a)pyrene despite robust mRNA transcriptional response
    • Yauk CL, Jackson K, Malowany M, Williams A. 2011. Lack of change in microRNA expression in adult mouse liver following treatment with benzo(a)pyrene despite robust mRNA transcriptional response. Mutat. Res. 722:131-39
    • (2011) Mutat. Res , vol.722 , pp. 131-139
    • Yauk, C.L.1    Jackson, K.2    Malowany, M.3    Williams, A.4
  • 92
    • 84855467600 scopus 로고    scopus 로고
    • Hepatic m RNA, micro RNA, and miR-34a-target responses in mice after 28 days exposure to doses of benzo(a)pyrene that elicit DNA damage and mutation
    • Malik AI, Williams A, Lemieux CL, White PA, Yauk CL. 2012. Hepatic m RNA, micro RNA, and miR-34a-target responses in mice after 28 days exposure to doses of benzo(a)pyrene that elicit DNA damage and mutation. Environ. Mol. Mutagen. 53:10-21
    • (2012) Environ. Mol. Mutagen , vol.53 , pp. 10-21
    • Malik, A.I.1    Williams, A.2    Lemieux, C.L.3    White, P.A.4    Yauk, C.L.5
  • 93
    • 79957824357 scopus 로고    scopus 로고
    • Pulmonary gene and microRNA expression changes in mice exposed to benzo(a)pyrene by oral gavage
    • Halappanavar S, WuD, Williams A, Kuo B, Godschalk RW, et al. 2011. Pulmonary gene and microRNA expression changes in mice exposed to benzo(a)pyrene by oral gavage. Toxicology 285:133-41
    • (2011) Toxicology , vol.285 , pp. 133-141
    • Halappanavar, S.1    Wu, D.2    Williams, A.3    Kuo Godschalk B, R.W.4
  • 94
    • 84862968214 scopus 로고    scopus 로고
    • Aberrant expression of miR-638 contributes to benzo(a)pyrene-induced human cell transformation
    • Li D, Wang Q, Liu C, Duan H, Zeng X, et al. 2012. Aberrant expression of miR-638 contributes to benzo(a)pyrene-induced human cell transformation. Toxicol. Sci. 125:382-91
    • (2012) Toxicol. Sci , vol.125 , pp. 382-391
    • Li, D.1    Wang, Q.2    Liu, C.3    Duan, H.4    Zeng, X.5
  • 95
    • 0028588925 scopus 로고
    • Short-term toxicity of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin in laboratory animals: Effects, mechanisms, and animal models
    • Pohjanvirta R, Tuomisto J. 1994. Short-term toxicity of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin in laboratory animals: effects, mechanisms, and animal models. Pharmacol. Rev. 46:483-549
    • (1994) Pharmacol. Rev , vol.46 , pp. 483-549
    • Pohjanvirta, R.1    Tuomisto, J.2
  • 96
    • 84860319933 scopus 로고    scopus 로고
    • MiRNA-34 intrinsically links p53 tumor suppressor and Wnt signaling
    • Cha YH, Kim NH, Park C, Lee I, Kim HS, Yook JI. 2012. miRNA-34 intrinsically links p53 tumor suppressor and Wnt signaling. Cell Cycle 11:1273-81
    • (2012) Cell Cycle , vol.11 , pp. 1273-1281
    • Cha, Y.H.1    Kim, N.H.2    Park, C.3    Lee, I.4    Kim, H.S.5    Yook, J.I.6
  • 97
    • 77249177182 scopus 로고    scopus 로고
    • Differential mutagenicity of aflatoxin B1 in the liver of neonatal and adult mice
    • Chen T, Heflich RH, Moore MM, Mei N. 2010. Differential mutagenicity of aflatoxin B1 in the liver of neonatal and adult mice. Environ. Mol. Mutagen. 51:156-63
    • (2010) Environ. Mol. Mutagen , vol.51 , pp. 156-163
    • Chen, T.1    Heflich, R.H.2    Moore, M.M.3    Mei, N.4
  • 98
    • 0025828517 scopus 로고
    • Selective G to T mutations of p53 gene in hepatocellular carcinoma from southern Africa
    • Bressac B, Kew M, Wands J, Ozturk M. 1991. Selective G to T mutations of p53 gene in hepatocellular carcinoma from southern Africa. Nature 350:429-31
    • (1991) Nature , vol.350 , pp. 429-431
    • Bressac, B.1    Kew, M.2    Wands, J.3    Ozturk, M.4
  • 100
    • 33646157967 scopus 로고    scopus 로고
    • Comprehensive analysis of microRNA expression patterns in hepatocellular carcinoma and non-tumorous tissues
    • Murakami T, Yasuda T, Saigo K, Urashima T, Toyoda H, et al. 2006. Comprehensive analysis of microRNA expression patterns in hepatocellular carcinoma and non-tumorous tissues. Oncogene 25:2537-45
    • (2006) Oncogene , vol.25 , pp. 2537-2545
    • Murakami, T.1    Yasuda, T.2    Saigo, K.3    Urashima, T.4    Toyoda, H.5
  • 101
    • 60749122411 scopus 로고    scopus 로고
    • RDX induces aberrant expression microRNAs in mouse brain and liver
    • Zhang B, Pan X. 2009. RDX induces aberrant expression microRNAs in mouse brain and liver. Environ. Health Perspect. 117:231-40
    • (2009) Environ. Health Perspect , vol.117 , pp. 231-240
    • Zhang, B.1    Pan, X.2
  • 102
    • 82755161786 scopus 로고    scopus 로고
    • Epigenetic regulation of microRNAs in cancer: An integrated review of literature
    • Kunej T, Godnic I, Ferdin J, Horvat S, Dovc P, Calin GA. 2011. Epigenetic regulation of microRNAs in cancer: an integrated review of literature. Mutat. Res. 717:77-84
    • (2011) Mutat. Res , vol.717 , pp. 77-84
    • Kunej, T.1    Godnic, I.2    Ferdin, J.3    Horvat, S.4    Dovc, P.5    Calin, G.A.6
  • 103
    • 67649349865 scopus 로고    scopus 로고
    • MicroRNA-125a-5p partly regulates the inflammatory response, lipid uptake, andORP9 expression in oxLDL-stimulated monocyte/macrophages
    • Chen T, Huang Z, Wang L, Wang Y, Wu F, et al. 2009. MicroRNA-125a-5p partly regulates the inflammatory response, lipid uptake, andORP9 expression in oxLDL-stimulated monocyte/macrophages. Cardiovasc. Res. 83:131-39
    • (2009) Cardiovasc. Res , vol.83 , pp. 131-139
    • Chen, T.1    Huang, Z.2    Wang, L.3    Wang, Y.4    Wu, F.5
  • 104
    • 77950600443 scopus 로고    scopus 로고
    • MicroRNA-dependent regulation of DNA methyltransferase-1 and tumor suppressor gene expression by interleukin-6 in human malignant cholangiocytes
    • Braconi C, Huang N, Patel T. 2010. MicroRNA-dependent regulation of DNA methyltransferase-1 and tumor suppressor gene expression by interleukin-6 in human malignant cholangiocytes. Hepatology 51:881-90
    • (2010) Hepatology , vol.51 , pp. 881-890
    • Braconi, C.1    Huang, N.2    Patel, T.3
  • 105
    • 66949118228 scopus 로고    scopus 로고
    • Interleukin-6modulates the expression of the bone morphogenic protein receptor type II through a novel STAT3-microRNA cluster 17/92 pathway
    • BrockM, Trenkmann M, Gay RE, Michel BA, Gay S, et al. 2009. Interleukin-6modulates the expression of the bone morphogenic protein receptor type II through a novel STAT3-microRNA cluster 17/92 pathway. Circ. Res. 104:1184-91
    • (2009) Circ. Res , vol.104 , pp. 1184-1191
    • Brockmtrenkmann, M.1    Gay, R.E.2    Michel, B.A.3    Gay, S.4
  • 106
    • 34548039517 scopus 로고    scopus 로고
    • Interleukin-6-dependent survival of multiple myeloma cells involves the Stat3-mediated induction of microRNA-21 through a highly conserved enhancer
    • LofflerD, Brocke-Heidrich K, Pfeifer G, Stocsits C, Hackerm uller J, et al. 2007. Interleukin-6-dependent survival of multiple myeloma cells involves the Stat3-mediated induction of microRNA-21 through a highly conserved enhancer. Blood 110:1330-33
    • (2007) Blood , vol.110 , pp. 1330-1333
    • Loffler, D.1    Brocke-Heidrich, K.2    Pfeifer, G.3    Stocsits, C.4    Hackermuller, J.5
  • 107
    • 71749096218 scopus 로고    scopus 로고
    • MiR-146a is critical for endotoxin-induced tolerance: Implication in innate immunity
    • Nahid MA, Pauley KM, Satoh M, Chan EK. 2009. miR-146a is critical for endotoxin-induced tolerance: implication in innate immunity. J. Biol. Chem. 284:34590-99
    • (2009) J. Biol. Chem , vol.284 , pp. 34590-34599
    • Nahid, M.A.1    Pauley, K.M.2    Satoh, M.3    Chan, E.K.4
  • 108
    • 79251592866 scopus 로고    scopus 로고
    • Mechanistic role of microRNA-146a in endotoxin-induced differential cross-regulation of TLR signaling
    • Nahid MA, Satoh M, Chan EK. 2011. Mechanistic role of microRNA-146a in endotoxin-induced differential cross-regulation of TLR signaling. J. Immunol. 186:1723-34
    • (2011) J. Immunol , vol.186 , pp. 1723-1734
    • Nahid, M.A.1    Satoh, M.2    Chan, E.K.3
  • 109
    • 79959387361 scopus 로고    scopus 로고
    • Targeting of microRNA-142-3p in dendritic cells regulates endotoxin-induced mortality
    • Sun Y, Varambally S, Maher CA, Cao Q, Chockley P, et al. 2012. Targeting of microRNA-142-3p in dendritic cells regulates endotoxin-induced mortality. Blood 117:6172-83
    • (2012) Blood , vol.117 , pp. 6172-6183
    • Sun, Y.1    Varambally, S.2    Maher, C.A.3    Cao, Q.4    Chockley, P.5
  • 111
    • 77954817589 scopus 로고    scopus 로고
    • Interleukin-17 is involved in α-naphthylisothiocyanate-induced liver injury in mice
    • Kobayashi M, Higuchi S, Mizuno K, Tsuneyama K, Fukami T, et al. 2010. Interleukin-17 is involved in α-naphthylisothiocyanate-induced liver injury in mice. Toxicology 275:50-57
    • (2010) Toxicology , vol.275 , pp. 50-57
    • Kobayashi, M.1    Higuchi, S.2    Mizuno, K.3    Tsuneyama, K.4    Fukami, T.5
  • 112
    • 84857037326 scopus 로고    scopus 로고
    • Involvement of immunerelated factors in diclofenac-induced acute liver injury in mice
    • Yano A, Higuchi S, Tsuneyama K, Fukami T, Nakajima M, Yokoi T. 2012. Involvement of immunerelated factors in diclofenac-induced acute liver injury in mice. Toxicology 293:107-14
    • (2012) Toxicology , vol.293 , pp. 107-114
    • Yano, A.1    Higuchi, S.2    Tsuneyama, K.3    Fukami, T.4    Nakajima, M.5    Yokoi, T.6
  • 113
    • 0027443904 scopus 로고
    • Cytokines down-regulate expression of major cytochrome P-450 enzymes in adult human hepatocytes in primary culture
    • Abdel-Razzak Z, Loyer P, Fautrel A, Gautier JC, Corcos L, et al. 1993. Cytokines down-regulate expression of major cytochrome P-450 enzymes in adult human hepatocytes in primary culture. Mol. Pharmacol. 44:707-15
    • (1993) Mol. Pharmacol , vol.44 , pp. 707-715
    • Abdel-Razzak, Z.1    Loyer, P.2    Fautrel, A.3    Gautier, J.C.4    Corcos, L.5
  • 114
    • 0034637122 scopus 로고    scopus 로고
    • Interleukin-6 negatively regulates the expression of pregnane X receptor and constitutively activated receptor in primary human hepatocytes
    • Pascussi JM, Gerbal-Chaloin S, Pichard-Garcia L, Daujat M, Fabre JM, et al. 2000. Interleukin-6 negatively regulates the expression of pregnane X receptor and constitutively activated receptor in primary human hepatocytes. Biochem. Biophys. Res. Commun. 274:707-13
    • (2000) Biochem. Biophys. Res. Commun , vol.274 , pp. 707-713
    • Pascussi, J.M.1    Gerbal-Chaloin, S.2    Pichard-Garcia, L.3    Daujat, M.4    Fabre, J.M.5
  • 115
    • 84865817146 scopus 로고    scopus 로고
    • Involvement of Th2 cytokines in the mouse model of flutamide-induced liver injury
    • Higuchi S, Kobayashi M, Yano A, Tsuneyama K, Fukami T, et al. 2012. Involvement of Th2 cytokines in the mouse model of flutamide-induced liver injury. J. Appl. Toxicol. 32:815-22
    • (2012) J. Appl. Toxicol , vol.32 , pp. 815-822
    • Higuchi, S.1    Kobayashi, M.2    Yano, A.3    Tsuneyama, K.4    Fukami, T.5
  • 119
    • 34447319406 scopus 로고    scopus 로고
    • Single nucleotide polymorphism associated with mature miR-125a alters the processing of pri-miRNA
    • Duan R, Pak C, Jin P. 2007. Single nucleotide polymorphism associated with mature miR-125a alters the processing of pri-miRNA. Hum. Mol. Genet. 16:1124-31
    • (2007) Hum. Mol. Genet , vol.16 , pp. 1124-1131
    • Duan, R.1    Pak, C.2    Jin, P.3
  • 120
    • 33847665108 scopus 로고    scopus 로고
    • Human polymorphism at microRNAs and microRNA target sites
    • Saunders MA, Liang H, Li WH. 2007. Human polymorphism at microRNAs and microRNA target sites. Proc. Natl. Acad. Sci. USA 104:3300-5
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 3300-3305
    • Saunders Ma Liang, H.1    Li, W.H.2
  • 121
    • 81755163596 scopus 로고    scopus 로고
    • Role of primary miRNA polymorphic variants in metastatic colon cancer patients treated with 5-fluorouracil and irinotecan
    • Boni V, Zarate R, Bandres E, Gomez MA, Maiello E, et al. 2011. Role of primary miRNA polymorphic variants in metastatic colon cancer patients treated with 5-fluorouracil and irinotecan. Pharmacogenomics J. 11:429-36
    • (2011) Pharmacogenomics J , vol.11 , pp. 429-436
    • Boni, V.1    Zarate, R.2    Bandres, E.3    Gomez, M.A.4    Maiello, E.5
  • 122
    • 52949119537 scopus 로고    scopus 로고
    • MicroRNA target site polymorphisms and human disease
    • Sethupathy P, Collins FS. 2008. MicroRNA target site polymorphisms and human disease. Trends Genet. 24:489-97
    • (2008) Trends Genet , vol.24 , pp. 489-497
    • Sethupathy, P.1    Collins, F.S.2
  • 123
    • 65649138698 scopus 로고    scopus 로고
    • MicroRNA polymorphisms: The future of pharmacogenomics, molecular epidemiology and individualized medicine
    • Mishra PJ, Bertino JR. 2009. MicroRNA polymorphisms: the future of pharmacogenomics, molecular epidemiology and individualized medicine. Pharmacogenomics 10:399-416
    • (2009) Pharmacogenomics , vol.10 , pp. 399-416
    • Mishra, P.J.1    Bertino, J.R.2
  • 124
    • 78549246589 scopus 로고    scopus 로고
    • Functional genetic variants in the 3′-untranslated region of sulfotransferase isoform 1A1 (SULT1A1) and their effect on enzymatic activity
    • Yu X, Dhakal IB, Beggs M, Edavana VK, Williams S, et al. 2010. Functional genetic variants in the 3′-untranslated region of sulfotransferase isoform 1A1 (SULT1A1) and their effect on enzymatic activity. Toxicol. Sci. 118:391-403
    • (2010) Toxicol. Sci , vol.118 , pp. 391-403
    • Yu, X.1    Dhakal, I.B.2    Beggs, M.3    Edavana, V.K.4    Williams, S.5
  • 125
    • 80053901650 scopus 로고    scopus 로고
    • A genome-wide survey for SNPs altering microRNA seed sites identifies functional candidates in GWAS
    • Richardson K, Lai CQ, Parnell LD, Lee YC, Ordovas JM. 2011. A genome-wide survey for SNPs altering microRNA seed sites identifies functional candidates in GWAS. BMC Genomics 12:504
    • (2011) BMC Genomics , vol.12 , pp. 504
    • Richardson, K.1    Lai, C.Q.2    Parnell, L.D.3    Lee, Y.C.4    Ordovas, J.M.5
  • 127
    • 79957633053 scopus 로고    scopus 로고
    • Differential allelic expression of c.1568C A at UGT2B15 is due to variation in a novel cis-regulatory element in the 3-UTR
    • Sun C, Southard C, Olopade OI, Di Rienzo AD. 2011. Differential allelic expression of c.1568C A at UGT2B15 is due to variation in a novel cis-regulatory element in the 3-UTR. Gene 481:24-28
    • (2011) Gene , vol.481 , pp. 24-28
    • Sun, C.1    Southard, C.2    Olopade, O.I.3    Di Rienzo, A.D.4
  • 128
    • 0034724324 scopus 로고    scopus 로고
    • Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo
    • Hoffmeyer S, Burk O, von Richter O, Arnold HP, Brockm oller J, et al. 2000. Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo. Proc. Natl. Acad. Sci. USA 97:3473-78
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 3473-3478
    • Hoffmeyer, S.1    Burk, O.2    Von Richter, O.3    Arnold, H.P.4    Brockm Oller, J.5
  • 129
    • 43449102192 scopus 로고    scopus 로고
    • Detection of elevated levels of tumor-associated microRNAs in serum of patients with diffuse large B-cell lymphoma
    • Lawrie CH, Gal S, Dunlop HM, Pushkaran B, Liggins AP, et al. 2008. Detection of elevated levels of tumor-associated microRNAs in serum of patients with diffuse large B-cell lymphoma. Br. J. Haematol. 141:672-75
    • (2008) Br. J. Haematol , vol.141 , pp. 672-675
    • Lawrie, C.H.1    Gal, S.2    Dunlop, H.M.3    Pushkaran, B.4    Liggins, A.P.5
  • 130
    • 82755187564 scopus 로고    scopus 로고
    • Extracellular microRNA: A new source of biomarkers
    • Etheridge A, Lee I, Hood L, Galas D, Wang K. 2011. Extracellular microRNA: a new source of biomarkers. Mutat. Res. 717:85-90
    • (2011) Mutat. Res , vol.717 , pp. 85-90
    • Etheridge, A.1    Lee, I.2    Hood, L.3    Galas, D.4    Wang, K.5
  • 133
    • 78649837734 scopus 로고    scopus 로고
    • Plasma microRNA-122 as a biomarker for viral-, alcohol-, and chemical-related hepatic diseases
    • Zhang Y, Jia Y, Zheng R, Guo Y, Wang Y, et al. 2010. Plasma microRNA-122 as a biomarker for viral-, alcohol-, and chemical-related hepatic diseases. Clin. Chem. 56:1830-38
    • (2010) Clin. Chem , vol.56 , pp. 1830-1838
    • Zhang, Y.1    Jia, Y.2    Zheng, R.3    Guo, Y.4    Wang, Y.5
  • 134
    • 84857166172 scopus 로고    scopus 로고
    • Plasma microRNA profiles in rat models of hepatocellular injury, cholestasis, and steatosis
    • Yamaura Y, NakajimaM, Takagi S, FukamiT, Tsuneyama K, Yokoi T. 2012. Plasma microRNA profiles in rat models of hepatocellular injury, cholestasis, and steatosis. PLoS ONE 7:e30250
    • (2012) PLoS ONE , vol.7
    • Yamaura, Y.1    Nakajima, M.2    Takagi, S.3    Fukami, T.4    Tsuneyama, K.5    Yokoi, T.6
  • 135
    • 84862954550 scopus 로고    scopus 로고
    • Identification of urinary microRNA profiles in rats that may diagnose hepatotoxicity
    • Yang X, Greenhaw J, Shi Q, Su Z, Qian F, et al. 2012. Identification of urinary microRNA profiles in rats that may diagnose hepatotoxicity. Toxicol. Sci. 125:335-44
    • (2012) Toxicol. Sci , vol.125 , pp. 335-344
    • Yang, X.1    Greenhaw, J.2    Shi, Q.3    Su, Z.4    Qian, F.5
  • 136
    • 80055038826 scopus 로고    scopus 로고
    • Circulating microRNAs as potential markers of human drug-induced liver injury
    • Starkey Lewis PJ, Dear J, Platt V, Simpson KJ, Craig DGN, et al. 2011. Circulating microRNAs as potential markers of human drug-induced liver injury. Hepatology 54:1767-76
    • (2011) Hepatology , vol.54 , pp. 1767-1776
    • Starkey Lewis, P.J.1    Dear, J.2    Platt, V.3    Simpson, K.J.4    Craig, D.G.N.5
  • 137
    • 66449105070 scopus 로고    scopus 로고
    • MicroRNA 18 and 124a down-regulate the glucocorticoid receptor: Implications for glucocorticoid responsiveness in the brain
    • Vreugdenhil E, Verissimo CS, Mariman R, Kamphorst JT, Barbosa JS, et al. 2009. MicroRNA 18 and 124a down-regulate the glucocorticoid receptor: implications for glucocorticoid responsiveness in the brain. Endocrinology 150:2220-28
    • (2009) Endocrinology , vol.150 , pp. 2220-2228
    • Vreugdenhil, E.1    Verissimo, C.S.2    Mariman, R.3    Kamphorst, J.T.4    Barbosa, J.S.5
  • 138
    • 80052570740 scopus 로고    scopus 로고
    • MiR-28 regulates Nrf2 expression through a Keap1-independent mechanism
    • Yang M, Yao Y, Eades G, Zhang Y, Zhou Q. 2011. miR-28 regulates Nrf2 expression through a Keap1-independent mechanism. Breast Cancer Res. Treat. 129:983-91
    • (2011) Breast Cancer Res. Treat , vol.129 , pp. 983-991
    • Yang, M.1    Yao, Y.2    Eades, G.3    Zhang, Y.4    Zhou, Q.5
  • 139
    • 81755171451 scopus 로고    scopus 로고
    • MiR-200a regulates Nrf2 activation by targeting Keap1 mRNA in breast cancer cells
    • Eades G, Yang M, Yao Y, Zhang Y, Zhou Q. 2011. miR-200a regulates Nrf2 activation by targeting Keap1 mRNA in breast cancer cells. J. Biol. Chem. 286:40725-33
    • (2011) J. Biol. Chem , vol.286 , pp. 40725-40733
    • Eades, G.1    Yang, M.2    Yao, Y.3    Zhang, Y.4    Zhou, Q.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.