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We thank J. E. Darnell Jr. for comments and guidance and for sharing the environment to initiate this work and P. Hoodless for providing a genomic HNF-3α clone. M.S. and S.A.D. also thank J. Smith and T. Minsa for giving us enthusiasm for science. M.S. is an Irma Hirschl Scholar, Pew Scholar, and Robert and Harriet Heilbrunn Professor. S.A.D. is a Naomi Judd American Liver and an Alexandrine and Alexander Sinsheimer Scholar. M.A.N. was supported by a postdoctoral fellowship of the Spanish Ministry of Education and Culture. D.D. was supported by the Fons de la Recherche en Sante du Quebec and the National Cancer Institute of Canada (NCIC). J.R. is a NCIC Terry Fox Research Scientist, a Medical Research Council Distinguished Scientist, and a Howard Hughes Medical Institute International Research Scholar. Supported in part by the American Diabetes Association and by the March of Dimes.
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