-
1
-
-
34250899722
-
Signal integration in the endoplasmic reticulum unfolded protein response
-
Ron D., Walter P. Signal integration in the endoplasmic reticulum unfolded protein response. Nat Rev Mol Cell Biol 2007, 8(7):519-529.
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, Issue.7
, pp. 519-529
-
-
Ron, D.1
Walter, P.2
-
2
-
-
79952844773
-
The unfolded protein response, degradation from endoplasmic reticulum and cancer
-
Tsai Y.C., Weissman A.M. The unfolded protein response, degradation from endoplasmic reticulum and cancer. Genes Cancer 2010, 1(7):764-778.
-
(2010)
Genes Cancer
, vol.1
, Issue.7
, pp. 764-778
-
-
Tsai, Y.C.1
Weissman, A.M.2
-
3
-
-
84883387793
-
Targeting the unfolded protein response in disease
-
Hetz C., Chevet E., Harding H.P. Targeting the unfolded protein response in disease. Nat Rev Drug Discov 2013, 12(9):703-719.
-
(2013)
Nat Rev Drug Discov
, vol.12
, Issue.9
, pp. 703-719
-
-
Hetz, C.1
Chevet, E.2
Harding, H.P.3
-
4
-
-
84896867224
-
The impact of autophagy on cell death modalities
-
Ryter S.W., Mizumura K., Choi A.M. The impact of autophagy on cell death modalities. Int J Cell Biol 2014, 2014:502676.
-
(2014)
Int J Cell Biol
, vol.2014
, pp. 502676
-
-
Ryter, S.W.1
Mizumura, K.2
Choi, A.M.3
-
5
-
-
33845459165
-
Autophagy is activated for cell survival after endoplasmic reticulum stress
-
Ogata M., Hino S., Saito A., Morikawa K., Kondo S., Kanemoto S., et al. Autophagy is activated for cell survival after endoplasmic reticulum stress. Mol Cell Biol 2006, 26(24):9220-9231.
-
(2006)
Mol Cell Biol
, vol.26
, Issue.24
, pp. 9220-9231
-
-
Ogata, M.1
Hino, S.2
Saito, A.3
Morikawa, K.4
Kondo, S.5
Kanemoto, S.6
-
6
-
-
78649338141
-
Autophagy and the integrated stress response
-
Kroemer G., Marino G., Levine B. Autophagy and the integrated stress response. Mol Cell 2010, 40(2):280-293.
-
(2010)
Mol Cell
, vol.40
, Issue.2
, pp. 280-293
-
-
Kroemer, G.1
Marino, G.2
Levine, B.3
-
7
-
-
37649005234
-
Autophagy in the pathogenesis of disease
-
Levine B., Kroemer G. Autophagy in the pathogenesis of disease. Cell 2008, 132(1):27-42.
-
(2008)
Cell
, vol.132
, Issue.1
, pp. 27-42
-
-
Levine, B.1
Kroemer, G.2
-
8
-
-
84904990966
-
Inside and out: the activities of senescence in cancer
-
Perez-Mancera P.A., Young A.R., Narita M. Inside and out: the activities of senescence in cancer. Nat Rev Cancer 2014, 14(8):547-558.
-
(2014)
Nat Rev Cancer
, vol.14
, Issue.8
, pp. 547-558
-
-
Perez-Mancera, P.A.1
Young, A.R.2
Narita, M.3
-
9
-
-
84923259951
-
Therapeutic targeting of autophagy in cancer. Part I: Molecular pathways controlling autophagy
-
Epub 2014 May 29
-
Nagelkerke A., Sweep F.C., Geurts-Moespot A., Bussink J, Span P.N. Therapeutic targeting of autophagy in cancer. Part I: Molecular pathways controlling autophagy. Semin Cancer Biol 2015, 31C:89-98. Epub 2014 May 29. 10.1016/j.semcancer.2014.05.004.
-
(2015)
Semin Cancer Biol
, vol.31C
, pp. 89-98
-
-
Nagelkerke, A.1
Sweep, F.C.2
Geurts-Moespot, A.3
Bussink, J.4
Span, P.N.5
-
10
-
-
84893825919
-
The four faces of autophagy: implications for cancer therapy
-
Gewirtz D.A. The four faces of autophagy: implications for cancer therapy. Cancer Res 2014, 74(3):647-651.
-
(2014)
Cancer Res
, vol.74
, Issue.3
, pp. 647-651
-
-
Gewirtz, D.A.1
-
11
-
-
84892832968
-
Oncogenic activation of MEK/ERK primes melanoma cells for adaptation to endoplasmic reticulum stress
-
Croft A., Tay K.H., Boyd S.C., Guo S.T., Jiang C.C., Lai F., et al. Oncogenic activation of MEK/ERK primes melanoma cells for adaptation to endoplasmic reticulum stress. J Invest Dermatol 2014, 134(2):488-497.
-
(2014)
J Invest Dermatol
, vol.134
, Issue.2
, pp. 488-497
-
-
Croft, A.1
Tay, K.H.2
Boyd, S.C.3
Guo, S.T.4
Jiang, C.C.5
Lai, F.6
-
12
-
-
84900312241
-
Endoplasmic reticulum stress in malignancy
-
Clarke H.J., Chambers J.E., Liniker E., Marciniak S.J. Endoplasmic reticulum stress in malignancy. Cancer Cell 2014, 25(5):563-573.
-
(2014)
Cancer Cell
, vol.25
, Issue.5
, pp. 563-573
-
-
Clarke, H.J.1
Chambers, J.E.2
Liniker, E.3
Marciniak, S.J.4
-
13
-
-
0027324844
-
Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase
-
Cox J.S., Shamu C.E., Walter P. Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase. Cell 1993, 73(6):1197-1206.
-
(1993)
Cell
, vol.73
, Issue.6
, pp. 1197-1206
-
-
Cox, J.S.1
Shamu, C.E.2
Walter, P.3
-
14
-
-
0027305620
-
A transmembrane protein with a cdc2+/CDC28-related kinase activity is required for signaling from the ER to the nucleus
-
Mori K., Ma W., Gething M.J., Sambrook J. A transmembrane protein with a cdc2+/CDC28-related kinase activity is required for signaling from the ER to the nucleus. Cell 1993, 74(4):743-756.
-
(1993)
Cell
, vol.74
, Issue.4
, pp. 743-756
-
-
Mori, K.1
Ma, W.2
Gething, M.J.3
Sambrook, J.4
-
15
-
-
0032525990
-
A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian cells
-
Tirasophon W., Welihinda A.A., Kaufman R.J. A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian cells. Genes Dev 1998, 12(12):1812-1824.
-
(1998)
Genes Dev
, vol.12
, Issue.12
, pp. 1812-1824
-
-
Tirasophon, W.1
Welihinda, A.A.2
Kaufman, R.J.3
-
16
-
-
0032190546
-
Cloning of mammalian Ire1 reveals diversity in the ER stress responses
-
Wang X.Z., Harding H.P., Zhang Y., Jolicoeur E.M., Kuroda M., Ron D. Cloning of mammalian Ire1 reveals diversity in the ER stress responses. EMBO J 1998, 17(19):5708-5717.
-
(1998)
EMBO J
, vol.17
, Issue.19
, pp. 5708-5717
-
-
Wang, X.Z.1
Harding, H.P.2
Zhang, Y.3
Jolicoeur, E.M.4
Kuroda, M.5
Ron, D.6
-
17
-
-
14944371187
-
The unfolded protein response sensor IRE1alpha is required at 2 distinct steps in B cell lymphopoiesis
-
Zhang K., Wong H.N., Song B., Miller C.N., Scheuner D., Kaufman R.J. The unfolded protein response sensor IRE1alpha is required at 2 distinct steps in B cell lymphopoiesis. J Clin Invest 2005, 115(2):268-281.
-
(2005)
J Clin Invest
, vol.115
, Issue.2
, pp. 268-281
-
-
Zhang, K.1
Wong, H.N.2
Song, B.3
Miller, C.N.4
Scheuner, D.5
Kaufman, R.J.6
-
18
-
-
70349756962
-
Function of IRE1 alpha in the placenta is essential for placental development and embryonic viability
-
Iwawaki T., Akai R., Yamanaka S., Kohno K. Function of IRE1 alpha in the placenta is essential for placental development and embryonic viability. Proc Natl Acad Sci U S A 2009, 106(39):16657-16662.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, Issue.39
, pp. 16657-16662
-
-
Iwawaki, T.1
Akai, R.2
Yamanaka, S.3
Kohno, K.4
-
19
-
-
0035094262
-
Increased sensitivity to dextran sodium sulfate colitis in IRE1beta-deficient mice
-
Bertolotti A., Wang X., Novoa I., Jungreis R., Schlessinger K., Cho J.H., et al. Increased sensitivity to dextran sodium sulfate colitis in IRE1beta-deficient mice. J Clin Invest 2001, 107(5):585-593.
-
(2001)
J Clin Invest
, vol.107
, Issue.5
, pp. 585-593
-
-
Bertolotti, A.1
Wang, X.2
Novoa, I.3
Jungreis, R.4
Schlessinger, K.5
Cho, J.H.6
-
20
-
-
84874251933
-
Negative feedback by IRE1beta optimizes mucin production in goblet cells
-
Tsuru A., Fujimoto N., Takahashi S., Saito M., Nakamura D., Iwano M., et al. Negative feedback by IRE1beta optimizes mucin production in goblet cells. Proc Natl Acad Sci U S A 2013, 110(8):2864-2869.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, Issue.8
, pp. 2864-2869
-
-
Tsuru, A.1
Fujimoto, N.2
Takahashi, S.3
Saito, M.4
Nakamura, D.5
Iwano, M.6
-
21
-
-
80052366845
-
Stressed out about obesity: IRE1alpha-XBP1 in metabolic disorders
-
Sha H., He Y., Yang L., Qi L. Stressed out about obesity: IRE1alpha-XBP1 in metabolic disorders. Trends Endocrinol Metab 2011, 22(9):374-381.
-
(2011)
Trends Endocrinol Metab
, vol.22
, Issue.9
, pp. 374-381
-
-
Sha, H.1
He, Y.2
Yang, L.3
Qi, L.4
-
22
-
-
68549092781
-
Regulated Ire1-dependent decay of messenger RNAs in mammalian cells
-
Hollien J., Lin J.H., Li H., Stevens N., Walter P., Weissman J.S. Regulated Ire1-dependent decay of messenger RNAs in mammalian cells. J Cell Biol 2009, 186(3):323-331.
-
(2009)
J Cell Biol
, vol.186
, Issue.3
, pp. 323-331
-
-
Hollien, J.1
Lin, J.H.2
Li, H.3
Stevens, N.4
Walter, P.5
Weissman, J.S.6
-
23
-
-
84867038186
-
Silencing of lipid metabolism genes through IRE1alpha-mediated mRNA decay lowers plasma lipids in mice
-
So J.S., Hur K.Y., Tarrio M., Ruda V., Frank-Kamenetsky M., Fitzgerald K., et al. Silencing of lipid metabolism genes through IRE1alpha-mediated mRNA decay lowers plasma lipids in mice. Cell Metab 2012, 16(4):487-499.
-
(2012)
Cell Metab
, vol.16
, Issue.4
, pp. 487-499
-
-
So, J.S.1
Hur, K.Y.2
Tarrio, M.3
Ruda, V.4
Frank-Kamenetsky, M.5
Fitzgerald, K.6
-
24
-
-
84861434815
-
RNA surveillance is required for endoplasmic reticulum homeostasis
-
Sakaki K., Yoshina S., Shen X., Han J., DeSantis M.R., Xiong M., et al. RNA surveillance is required for endoplasmic reticulum homeostasis. Proc Natl Acad Sci U S A 2012, 109(21):8079-8084.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, Issue.21
, pp. 8079-8084
-
-
Sakaki, K.1
Yoshina, S.2
Shen, X.3
Han, J.4
DeSantis, M.R.5
Xiong, M.6
-
25
-
-
33745893809
-
Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response
-
Hollien J., Weissman J.S. Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response. Science 2006, 313(5783):104-107.
-
(2006)
Science
, vol.313
, Issue.5783
, pp. 104-107
-
-
Hollien, J.1
Weissman, J.S.2
-
26
-
-
84868525253
-
IRE1alpha cleaves select microRNAs during ER stress to derepress translation of proapoptotic caspase-2
-
Upton J.P., Wang L., Han D., Wang E.S., Huskey N.E., Lim L., et al. IRE1alpha cleaves select microRNAs during ER stress to derepress translation of proapoptotic caspase-2. Science 2012, 338(6108):818-822.
-
(2012)
Science
, vol.338
, Issue.6108
, pp. 818-822
-
-
Upton, J.P.1
Wang, L.2
Han, D.3
Wang, E.S.4
Huskey, N.E.5
Lim, L.6
-
27
-
-
84876906034
-
MicroRNA-199a-5p protects hepatocytes from bile acid-induced sustained endoplasmic reticulum stress
-
Dai B.H., Geng L., Wang Y., Sui C.J., Xie F., Shen R.X., et al. microRNA-199a-5p protects hepatocytes from bile acid-induced sustained endoplasmic reticulum stress. Cell Death Dis 2013, 4:pe604.
-
(2013)
Cell Death Dis
, vol.4
, pp. pe604
-
-
Dai, B.H.1
Geng, L.2
Wang, Y.3
Sui, C.J.4
Xie, F.5
Shen, R.X.6
-
28
-
-
84879155370
-
Endoplasmic reticulum stress signaling: the microRNA connection
-
Maurel M., Chevet E. Endoplasmic reticulum stress signaling: the microRNA connection. Am J Physiol Cell Physiol 2013, 304(12):C1117-C1126.
-
(2013)
Am J Physiol Cell Physiol
, vol.304
, Issue.12
, pp. C1117-C1126
-
-
Maurel, M.1
Chevet, E.2
-
29
-
-
0034650851
-
An essential role in liver development for transcription factor XBP-1
-
Reimold A.M., Etkin A., Clauss I., Perkins A., Friend D.S., Zhang J., et al. An essential role in liver development for transcription factor XBP-1. Genes Dev 2000, 14(2):152-157.
-
(2000)
Genes Dev
, vol.14
, Issue.2
, pp. 152-157
-
-
Reimold, A.M.1
Etkin, A.2
Clauss, I.3
Perkins, A.4
Friend, D.S.5
Zhang, J.6
-
30
-
-
0035913294
-
Plasma cell differentiation requires the transcription factor XBP-1
-
Reimold A.M., Iwakoshi N.N., Manis J., Vallabhajosyula P., Szomolanyi-Tsuda E., Gravallese E.M., et al. Plasma cell differentiation requires the transcription factor XBP-1. Nature 2001, 412(6844):300-307.
-
(2001)
Nature
, vol.412
, Issue.6844
, pp. 300-307
-
-
Reimold, A.M.1
Iwakoshi, N.N.2
Manis, J.3
Vallabhajosyula, P.4
Szomolanyi-Tsuda, E.5
Gravallese, E.M.6
-
31
-
-
3142658576
-
XBP1: downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation
-
Shaffer A.L., Shapiro-Shelef M., Iwakoshi N.N., Lee A.H., Qian S.B., Zhao H., et al. XBP1: downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation. Immunity 2004, 21(1):81-93.
-
(2004)
Immunity
, vol.21
, Issue.1
, pp. 81-93
-
-
Shaffer, A.L.1
Shapiro-Shelef, M.2
Iwakoshi, N.N.3
Lee, A.H.4
Qian, S.B.5
Zhao, H.6
-
32
-
-
70350452319
-
XBP1 governs late events in plasma cell differentiation and is not required for antigen-specific memory B cell development
-
Todd D.J., McHeyzer-Williams L.J., Kowal C., Lee A.H., Volpe B.T., Diamond B., et al. XBP1 governs late events in plasma cell differentiation and is not required for antigen-specific memory B cell development. J Exp Med 2009, 206(10):2151-2159.
-
(2009)
J Exp Med
, vol.206
, Issue.10
, pp. 2151-2159
-
-
Todd, D.J.1
McHeyzer-Williams, L.J.2
Kowal, C.3
Lee, A.H.4
Volpe, B.T.5
Diamond, B.6
-
33
-
-
33747849846
-
Regulation of insulin biosynthesis in pancreatic beta cells by an endoplasmic reticulum-resident protein kinase IRE1
-
Lipson K.L., Fonseca S.G., Ishigaki S., Nguyen L.X., Foss E., Bortell R., et al. Regulation of insulin biosynthesis in pancreatic beta cells by an endoplasmic reticulum-resident protein kinase IRE1. Cell Metab 2006, 4(3):245-254.
-
(2006)
Cell Metab
, vol.4
, Issue.3
, pp. 245-254
-
-
Lipson, K.L.1
Fonseca, S.G.2
Ishigaki, S.3
Nguyen, L.X.4
Foss, E.5
Bortell, R.6
-
34
-
-
45749114525
-
The role of IRE1alpha in the degradation of insulin mRNA in pancreatic beta-cells
-
Lipson K.L., Ghosh R., Urano F. The role of IRE1alpha in the degradation of insulin mRNA in pancreatic beta-cells. PLoS ONE 2008, 3(2):e1648.
-
(2008)
PLoS ONE
, vol.3
, Issue.2
, pp. e1648
-
-
Lipson, K.L.1
Ghosh, R.2
Urano, F.3
-
35
-
-
79957773163
-
Dual and opposing roles of the unfolded protein response regulated by IRE1alpha and XBP1 in proinsulin processing and insulin secretion
-
Lee A.H., Heidtman K., Hotamisligil G.S., Glimcher L.H. Dual and opposing roles of the unfolded protein response regulated by IRE1alpha and XBP1 in proinsulin processing and insulin secretion. Proc Natl Acad Sci U S A 2011, 108(21):8885-8890.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, Issue.21
, pp. 8885-8890
-
-
Lee, A.H.1
Heidtman, K.2
Hotamisligil, G.S.3
Glimcher, L.H.4
-
36
-
-
85027947620
-
The IRE1alpha-XBP1 pathway regulates metabolic stress-induced compensatory proliferation of pancreatic beta-cells
-
Xu T., Yang L., Yan C., Wang X., Huang P., Zhao F., et al. The IRE1alpha-XBP1 pathway regulates metabolic stress-induced compensatory proliferation of pancreatic beta-cells. Cell Res 2014, 24(9):1137-1140.
-
(2014)
Cell Res
, vol.24
, Issue.9
, pp. 1137-1140
-
-
Xu, T.1
Yang, L.2
Yan, C.3
Wang, X.4
Huang, P.5
Zhao, F.6
-
37
-
-
30844472027
-
Activation of the endoplasmic reticulum stress pathway is associated with survival of myeloma cells
-
Nakamura M., Gotoh T., Okuno Y., Tatetsu H., Sonoki T., Uneda S., et al. Activation of the endoplasmic reticulum stress pathway is associated with survival of myeloma cells. Leuk Lymphoma 2006, 47(3):531-539.
-
(2006)
Leuk Lymphoma
, vol.47
, Issue.3
, pp. 531-539
-
-
Nakamura, M.1
Gotoh, T.2
Okuno, Y.3
Tatetsu, H.4
Sonoki, T.5
Uneda, S.6
-
38
-
-
77955486614
-
XBP1s levels are implicated in the biology and outcome of myeloma mediating different clinical outcomes to thalidomide-based treatments
-
Bagratuni T., Wu P., Gonzalez de Castro D., Davenport E.L., Dickens N.J., Walker B.A., et al. XBP1s levels are implicated in the biology and outcome of myeloma mediating different clinical outcomes to thalidomide-based treatments. Blood 2010, 116(2):250-253.
-
(2010)
Blood
, vol.116
, Issue.2
, pp. 250-253
-
-
Bagratuni, T.1
Wu, P.2
Gonzalez de Castro, D.3
Davenport, E.L.4
Dickens, N.J.5
Walker, B.A.6
-
39
-
-
79251589342
-
Identification of an Ire1alpha endonuclease specific inhibitor with cytotoxic activity against human multiple myeloma
-
Papandreou I., Denko N.C., Olson M., Van Melckebeke H., Lust S., Tam A., et al. Identification of an Ire1alpha endonuclease specific inhibitor with cytotoxic activity against human multiple myeloma. Blood 2011, 117(4):1311-1314.
-
(2011)
Blood
, vol.117
, Issue.4
, pp. 1311-1314
-
-
Papandreou, I.1
Denko, N.C.2
Olson, M.3
Van Melckebeke, H.4
Lust, S.5
Tam, A.6
-
40
-
-
84859587957
-
The molecular basis for selective inhibition of unconventional mRNA splicing by an IRE1-binding small molecule
-
Cross B.C., Bond P.J., Sadowski P.G., Jha B.K., Zak J., Goodman J.M., et al. The molecular basis for selective inhibition of unconventional mRNA splicing by an IRE1-binding small molecule. Proc Natl Acad Sci U S A 2012, 109(15):E869-E878.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, Issue.15
, pp. E869-E878
-
-
Cross, B.C.1
Bond, P.J.2
Sadowski, P.G.3
Jha, B.K.4
Zak, J.5
Goodman, J.M.6
-
41
-
-
0043193876
-
Proteasome inhibitors disrupt the unfolded protein response in myeloma cells
-
Lee A.H., Iwakoshi N.N., Anderson K.C., Glimcher L.H. Proteasome inhibitors disrupt the unfolded protein response in myeloma cells. Proc Natl Acad Sci U S A 2003, 100(17):9946-9951.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, Issue.17
, pp. 9946-9951
-
-
Lee, A.H.1
Iwakoshi, N.N.2
Anderson, K.C.3
Glimcher, L.H.4
-
42
-
-
84866001506
-
Identification of Toyocamycin, an agent cytotoxic for multiple myeloma cells, as a potent inhibitor of ER stress-induced XBP1 mRNA splicing
-
Ri M., Tashiro E., Oikawa D., Shinjo S., Tokuda M., Yokouchi Y., et al. Identification of Toyocamycin, an agent cytotoxic for multiple myeloma cells, as a potent inhibitor of ER stress-induced XBP1 mRNA splicing. Blood Cancer J 2012, 2(7):e79.
-
(2012)
Blood Cancer J
, vol.2
, Issue.7
, pp. e79
-
-
Ri, M.1
Tashiro, E.2
Oikawa, D.3
Shinjo, S.4
Tokuda, M.5
Yokouchi, Y.6
-
43
-
-
34047136169
-
The differentiation and stress response factor XBP-1 drives multiple myeloma pathogenesis
-
Carrasco D.R., Sukhdeo K., Protopopova M., Sinha R., Enos M., Carrasco D.E., et al. The differentiation and stress response factor XBP-1 drives multiple myeloma pathogenesis. Cancer Cell 2007, 11(4):349-360.
-
(2007)
Cancer Cell
, vol.11
, Issue.4
, pp. 349-360
-
-
Carrasco, D.R.1
Sukhdeo, K.2
Protopopova, M.3
Sinha, R.4
Enos, M.5
Carrasco, D.E.6
-
44
-
-
33847663808
-
Overexpression of human X-box binding protein 1 (XBP-1) in colorectal adenomas and adenocarcinomas
-
Fujimoto T., Yoshimatsu K., Watanabe K., Yokomizo H., Otani T., Matsumoto A., et al. Overexpression of human X-box binding protein 1 (XBP-1) in colorectal adenomas and adenocarcinomas. Anticancer Res 2007, 27(1A):127-131.
-
(2007)
Anticancer Res
, vol.27
, Issue.1 A
, pp. 127-131
-
-
Fujimoto, T.1
Yoshimatsu, K.2
Watanabe, K.3
Yokomizo, H.4
Otani, T.5
Matsumoto, A.6
-
45
-
-
84885437087
-
ER stress transcription factor Xbp1 suppresses intestinal tumorigenesis and directs intestinal stem cells
-
Niederreiter L., Fritz T.M., Adolph T.E., Krismer A.M., Offner F.A., Tschurtschenthaler M., et al. ER stress transcription factor Xbp1 suppresses intestinal tumorigenesis and directs intestinal stem cells. J Exp Med 2013, 210(10):2041-2056.
-
(2013)
J Exp Med
, vol.210
, Issue.10
, pp. 2041-2056
-
-
Niederreiter, L.1
Fritz, T.M.2
Adolph, T.E.3
Krismer, A.M.4
Offner, F.A.5
Tschurtschenthaler, M.6
-
46
-
-
84897541350
-
XBP1 promotes triple-negative breast cancer by controlling the HIF1alpha pathway
-
Chen X., Iliopoulos D., Zhang Q., Tang Q., Greenblatt M.B., Hatziapostolou M., et al. XBP1 promotes triple-negative breast cancer by controlling the HIF1alpha pathway. Nature 2014, 508(7494):103-107.
-
(2014)
Nature
, vol.508
, Issue.7494
, pp. 103-107
-
-
Chen, X.1
Iliopoulos, D.2
Zhang, Q.3
Tang, Q.4
Greenblatt, M.B.5
Hatziapostolou, M.6
-
47
-
-
34547114745
-
IRE1 signaling is essential for ischemia-induced vascular endothelial growth factor-A expression and contributes to angiogenesis and tumor growth in vivo
-
Drogat B., Auguste P., Nguyen DT, Bouchecareilh M., Pineau R., Nalbantoglu J., et al. IRE1 signaling is essential for ischemia-induced vascular endothelial growth factor-A expression and contributes to angiogenesis and tumor growth in vivo. Cancer Res 2007, 67(14):6700-6707.
-
(2007)
Cancer Res
, vol.67
, Issue.14
, pp. 6700-6707
-
-
Drogat, B.1
Auguste, P.2
Nguyen, DT3
Bouchecareilh, M.4
Pineau, R.5
Nalbantoglu, J.6
-
48
-
-
77957288028
-
Inositol-requiring enzyme 1alpha is a key regulator of angiogenesis and invasion in malignant glioma
-
Auf G., Jabouille A., Guerit S., Pineau R., Delugin M., Bouchecareilh M., et al. Inositol-requiring enzyme 1alpha is a key regulator of angiogenesis and invasion in malignant glioma. Proc Natl Acad Sci U S A 2010, 107(35):15553-15558.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, Issue.35
, pp. 15553-15558
-
-
Auf, G.1
Jabouille, A.2
Guerit, S.3
Pineau, R.4
Delugin, M.5
Bouchecareilh, M.6
-
49
-
-
4344598305
-
Nck-dependent activation of extracellular signal-regulated kinase-1 and regulation of cell survival during endoplasmic reticulum stress
-
Nguyen DT, Kebache S., Fazel A., Wong H.N., Jenna S., Emadali A., et al. Nck-dependent activation of extracellular signal-regulated kinase-1 and regulation of cell survival during endoplasmic reticulum stress. Mol Biol Cell 2004, 15(9):4248-4260.
-
(2004)
Mol Biol Cell
, vol.15
, Issue.9
, pp. 4248-4260
-
-
Nguyen, DT1
Kebache, S.2
Fazel, A.3
Wong, H.N.4
Jenna, S.5
Emadali, A.6
-
50
-
-
84871911924
-
Comparison of mRNA localization and regulation during endoplasmic reticulum stress in Drosophila cells
-
Gaddam D., Stevens N., Hollien J. Comparison of mRNA localization and regulation during endoplasmic reticulum stress in Drosophila cells. Mol Biol Cell 2013, 24(1):14-20.
-
(2013)
Mol Biol Cell
, vol.24
, Issue.1
, pp. 14-20
-
-
Gaddam, D.1
Stevens, N.2
Hollien, J.3
-
51
-
-
84872173393
-
Autocrine control of glioma cells adhesion and migration through IRE1alpha-mediated cleavage of SPARC mRNA
-
Dejeans N., Pluquet O., Lhomond S., Grise F., Bouchecareilh M., Juin A., et al. Autocrine control of glioma cells adhesion and migration through IRE1alpha-mediated cleavage of SPARC mRNA. J Cell Sci 2012, 125(Pt 18):4278-4287.
-
(2012)
J Cell Sci
, vol.125
, pp. 4278-4287
-
-
Dejeans, N.1
Pluquet, O.2
Lhomond, S.3
Grise, F.4
Bouchecareilh, M.5
Juin, A.6
-
52
-
-
84878047476
-
MicroRNA-1291-mediated silencing of IRE1alpha enhances Glypican-3 expression
-
Maurel M., Dejeans N., Taouji S., Chevet E., Grosset CF. MicroRNA-1291-mediated silencing of IRE1alpha enhances Glypican-3 expression. RNA 2013, 19(6):778-788.
-
(2013)
RNA
, vol.19
, Issue.6
, pp. 778-788
-
-
Maurel, M.1
Dejeans, N.2
Taouji, S.3
Chevet, E.4
Grosset, C.F.5
-
53
-
-
33947659004
-
Glypican-3: from the mutations of Simpson-Golabi-Behmel genetic syndrome to a tumor marker for hepatocellular carcinoma
-
Jakubovic B.D., Jothy S. Glypican-3: from the mutations of Simpson-Golabi-Behmel genetic syndrome to a tumor marker for hepatocellular carcinoma. Exp Mol Pathol 2007, 82(2):184-189.
-
(2007)
Exp Mol Pathol
, vol.82
, Issue.2
, pp. 184-189
-
-
Jakubovic, B.D.1
Jothy, S.2
-
54
-
-
22244480967
-
Glypican-3 promotes the growth of hepatocellular carcinoma by stimulating canonical Wnt signaling
-
Capurro M.I., Xiang YY, Lobe C., Filmus J. Glypican-3 promotes the growth of hepatocellular carcinoma by stimulating canonical Wnt signaling. Cancer Res 2005, 65(14):6245-6254.
-
(2005)
Cancer Res
, vol.65
, Issue.14
, pp. 6245-6254
-
-
Capurro, M.I.1
Xiang, YY2
Lobe, C.3
Filmus, J.4
-
55
-
-
59649111087
-
The unfolded protein response signals through high-order assembly of Ire1
-
Korennykh A.V., Egea P.F., Korostelev A.A., Finer-Moore J., Zhang C., Shokat K.M., et al. The unfolded protein response signals through high-order assembly of Ire1. Nature 2009, 457(7230):687-693.
-
(2009)
Nature
, vol.457
, Issue.7230
, pp. 687-693
-
-
Korennykh, A.V.1
Egea, P.F.2
Korostelev, A.A.3
Finer-Moore, J.4
Zhang, C.5
Shokat, K.M.6
-
56
-
-
80052227409
-
A conserved structural determinant located at the interdomain region of mammalian inositol-requiring enzyme 1alpha
-
Xue Z., He Y., Ye K., Gu Z., Mao Y., Qi L. A conserved structural determinant located at the interdomain region of mammalian inositol-requiring enzyme 1alpha. J Biol Chem 2011, 286(35):30859-30866.
-
(2011)
J Biol Chem
, vol.286
, Issue.35
, pp. 30859-30866
-
-
Xue, Z.1
He, Y.2
Ye, K.3
Gu, Z.4
Mao, Y.5
Qi, L.6
-
57
-
-
84905492694
-
Allosteric inhibition of the IRE1alpha RNase preserves cell viability and function during endoplasmic reticulum stress
-
Ghosh R., Wang L., Wang E.S., Perera B.G., Igbaria A., Morita S., et al. Allosteric inhibition of the IRE1alpha RNase preserves cell viability and function during endoplasmic reticulum stress. Cell 2014, 158(3):534-548.
-
(2014)
Cell
, vol.158
, Issue.3
, pp. 534-548
-
-
Ghosh, R.1
Wang, L.2
Wang, E.S.3
Perera, B.G.4
Igbaria, A.5
Morita, S.6
-
58
-
-
84903749341
-
Cell death. Opposing unfolded-protein-response signals converge on death receptor 5 to control apoptosis
-
Lu M., Lawrence D.A., Marsters S., Acosta-Alvear D, Kimmig P., Mendez A.S., et al. Cell death. Opposing unfolded-protein-response signals converge on death receptor 5 to control apoptosis. Science 2014, 345(6192):98-101.
-
(2014)
Science
, vol.345
, Issue.6192
, pp. 98-101
-
-
Lu, M.1
Lawrence, D.A.2
Marsters, S.3
Acosta-Alvear, D.4
Kimmig, P.5
Mendez, A.S.6
-
60
-
-
33746377894
-
Protein misfolding, functional amyloid, and human disease
-
Chiti F., Dobson C.M. Protein misfolding, functional amyloid, and human disease. Annu Rev Biochem 2006, 75:333-366.
-
(2006)
Annu Rev Biochem
, vol.75
, pp. 333-366
-
-
Chiti, F.1
Dobson, C.M.2
-
61
-
-
84860118506
-
The delicate balance between secreted protein folding and endoplasmic reticulum-associated degradation in human physiology
-
Guerriero C.J., Brodsky J.L. The delicate balance between secreted protein folding and endoplasmic reticulum-associated degradation in human physiology. Physiol Rev 2012, 92(2):537-576.
-
(2012)
Physiol Rev
, vol.92
, Issue.2
, pp. 537-576
-
-
Guerriero, C.J.1
Brodsky, J.L.2
-
62
-
-
0029811218
-
Role of 26S proteasome and HRD genes in the degradation of 3-hydroxy-3-methylglutaryl-CoA reductase: an integral endoplasmic reticulum membrane protein
-
Hampton R.Y., Gardner R.G., Rine J. Role of 26S proteasome and HRD genes in the degradation of 3-hydroxy-3-methylglutaryl-CoA reductase: an integral endoplasmic reticulum membrane protein. Mol Biol Cell 1996, 7(12):2029-2044.
-
(1996)
Mol Biol Cell
, vol.7
, Issue.12
, pp. 2029-2044
-
-
Hampton, R.Y.1
Gardner, R.G.2
Rine, J.3
-
63
-
-
0034597161
-
Endoplasmic reticulum degradation requires lumen to cytosol signaling. Transmembrane control of Hrd1p by Hrd3p
-
Gardner R.G., Swarbrick G.M., Bays NW, Cronin S.R., Wilhovsky S., Seelig L., et al. Endoplasmic reticulum degradation requires lumen to cytosol signaling. Transmembrane control of Hrd1p by Hrd3p. J Cell Biol 2000, 151(1):69-82.
-
(2000)
J Cell Biol
, vol.151
, Issue.1
, pp. 69-82
-
-
Gardner, R.G.1
Swarbrick, G.M.2
Bays, NW3
Cronin, S.R.4
Wilhovsky, S.5
Seelig, L.6
-
64
-
-
33750359201
-
SEL1L: the homologue of yeast Hrd3p, is involved in protein dislocation from the mammalian ER
-
Mueller B., Lilley B.N., Ploegh H.L. SEL1L: the homologue of yeast Hrd3p, is involved in protein dislocation from the mammalian ER. J Cell Biol 2006, 175(2):261-270.
-
(2006)
J Cell Biol
, vol.175
, Issue.2
, pp. 261-270
-
-
Mueller, B.1
Lilley, B.N.2
Ploegh, H.L.3
-
65
-
-
50449107542
-
SEL1L nucleates a protein complex required for dislocation of misfolded glycoproteins
-
Mueller B., Klemm E.J., Spooner E., Claessen J.H., Ploegh HL. SEL1L nucleates a protein complex required for dislocation of misfolded glycoproteins. Proc Natl Acad Sci U S A 2008, 105(34):12325-12330.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, Issue.34
, pp. 12325-12330
-
-
Mueller, B.1
Klemm, E.J.2
Spooner, E.3
Claessen, J.H.4
Ploegh, H.L.5
-
66
-
-
84255169603
-
Defining human ERAD networks through an integrative mapping strategy
-
Christianson J.C., Olzmann J.A., Shaler T.A., Sowa M.E., Bennett E.J., Richter C.M., et al. Defining human ERAD networks through an integrative mapping strategy. Nat Cell Biol 2012, 14(1):93-105.
-
(2012)
Nat Cell Biol
, vol.14
, Issue.1
, pp. 93-105
-
-
Christianson, J.C.1
Olzmann, J.A.2
Shaler, T.A.3
Sowa, M.E.4
Bennett, E.J.5
Richter, C.M.6
-
67
-
-
77951564358
-
Deficiency of suppressor enhancer lin12 1 like (SEL1L) in mice leads to systemic endoplasmic reticulum stress and embryonic lethality
-
Francisco A.B., Singh R., Li S., Vani A.K., Yang L., Munroe R.J., et al. Deficiency of suppressor enhancer lin12 1 like (SEL1L) in mice leads to systemic endoplasmic reticulum stress and embryonic lethality. J Biol Chem 2010, 285(18):13694-13703.
-
(2010)
J Biol Chem
, vol.285
, Issue.18
, pp. 13694-13703
-
-
Francisco, A.B.1
Singh, R.2
Li, S.3
Vani, A.K.4
Yang, L.5
Munroe, R.J.6
-
68
-
-
84893517295
-
Sel1L is indispensable for mammalian endoplasmic reticulum-associated degradation: endoplasmic reticulum homeostasis, and survival
-
Sun S., Shi G., Han X., Francisco A.B., Ji Y., Mendonca N., et al. Sel1L is indispensable for mammalian endoplasmic reticulum-associated degradation: endoplasmic reticulum homeostasis, and survival. Proc Natl Acad Sci U S A 2014, 111(5):E582-E591.
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, Issue.5
, pp. E582-E591
-
-
Sun, S.1
Shi, G.2
Han, X.3
Francisco, A.B.4
Ji, Y.5
Mendonca, N.6
-
69
-
-
77649283223
-
SEL1L deficiency impairs growth and differentiation of pancreatic epithelial cells
-
Li S., Francisco A.B., Munroe R.J., Schimenti J.C., Long Q. SEL1L deficiency impairs growth and differentiation of pancreatic epithelial cells. BMC Dev Biol 2010, 10:19.
-
(2010)
BMC Dev Biol
, vol.10
, pp. 19
-
-
Li, S.1
Francisco, A.B.2
Munroe, R.J.3
Schimenti, J.C.4
Long, Q.5
-
70
-
-
84913536702
-
The ER-associated degradation adaptor protein Sel1L regulates LPL secretion and lipid metabolism
-
Sha H., Sun S., Francisco A.B., Ehrhardt N., Xue Z., Liu L., et al. The ER-associated degradation adaptor protein Sel1L regulates LPL secretion and lipid metabolism. Cell Metab 2014, 20(3):458-470.
-
(2014)
Cell Metab
, vol.20
, Issue.3
, pp. 458-470
-
-
Sha, H.1
Sun, S.2
Francisco, A.B.3
Ehrhardt, N.4
Xue, Z.5
Liu, L.6
-
71
-
-
33646376968
-
A novel polymorphism in SEL1L confers susceptibility to Alzheimer's disease
-
Saltini G., Dominici R., Lovati C., Cattaneo M., Michelini S., Malferrari G., et al. A novel polymorphism in SEL1L confers susceptibility to Alzheimer's disease. Neurosci Lett 2006, 398(1-2):53-58.
-
(2006)
Neurosci Lett
, vol.398
, Issue.1-2
, pp. 53-58
-
-
Saltini, G.1
Dominici, R.2
Lovati, C.3
Cattaneo, M.4
Michelini, S.5
Malferrari, G.6
-
72
-
-
84875076497
-
A SEL1L mutation links a canine progressive early-onset cerebellar ataxia to the endoplasmic reticulum-associated protein degradation (ERAD) machinery
-
Kyostila K., Cizinauskas S., Seppala E.H., Suhonen E., Jeserevics J., Sukura A., et al. A SEL1L mutation links a canine progressive early-onset cerebellar ataxia to the endoplasmic reticulum-associated protein degradation (ERAD) machinery. PLoS Genet 2012, 8(6):e1002759.
-
(2012)
PLoS Genet
, vol.8
, Issue.6
, pp. e1002759
-
-
Kyostila, K.1
Cizinauskas, S.2
Seppala, E.H.3
Suhonen, E.4
Jeserevics, J.5
Sukura, A.6
-
73
-
-
20044394518
-
Essential role of synoviolin in embryogenesis
-
Yagishita N., Ohneda K., Amano T., Yamasaki S., Sugiura A., Tsuchimochi K., et al. Essential role of synoviolin in embryogenesis. J Biol Chem 2005, 280(9):7909-7916.
-
(2005)
J Biol Chem
, vol.280
, Issue.9
, pp. 7909-7916
-
-
Yagishita, N.1
Ohneda, K.2
Amano, T.3
Yamasaki, S.4
Sugiura, A.5
Tsuchimochi, K.6
-
74
-
-
84898874270
-
Hrd1 suppresses Nrf2-mediated cellular protection during liver cirrhosis
-
Wu T., Zhao F., Gao B., Tan C., Yagishita N., Nakajima T., et al. Hrd1 suppresses Nrf2-mediated cellular protection during liver cirrhosis. Genes Dev 2014, 28(7):708-722.
-
(2014)
Genes Dev
, vol.28
, Issue.7
, pp. 708-722
-
-
Wu, T.1
Zhao, F.2
Gao, B.3
Tan, C.4
Yagishita, N.5
Nakajima, T.6
-
75
-
-
84911924274
-
Hrd1-mediated BLIMP-1 ubiquitination promotes dendritic cell MHCII expression for CD4 T cell priming during inflammation
-
Yang H., Qiu Q., Gao B., Kong S., Lin Z., Fang D. Hrd1-mediated BLIMP-1 ubiquitination promotes dendritic cell MHCII expression for CD4 T cell priming during inflammation. J Exp Med 2014, 211(12):2467-2479.
-
(2014)
J Exp Med
, vol.211
, Issue.12
, pp. 2467-2479
-
-
Yang, H.1
Qiu, Q.2
Gao, B.3
Kong, S.4
Lin, Z.5
Fang, D.6
-
76
-
-
33644822689
-
SEL1L affects human pancreatic cancer cell cycle and invasiveness through modulation of PTEN and genes related to cell-matrix interactions
-
Cattaneo M., Fontanella E., Canton C., Delia D., Biunno I. SEL1L affects human pancreatic cancer cell cycle and invasiveness through modulation of PTEN and genes related to cell-matrix interactions. Neoplasia 2005, 7(11):1030-1038.
-
(2005)
Neoplasia
, vol.7
, Issue.11
, pp. 1030-1038
-
-
Cattaneo, M.1
Fontanella, E.2
Canton, C.3
Delia, D.4
Biunno, I.5
-
77
-
-
84859744603
-
A single-nucleotide polymorphism in tumor suppressor gene SEL1L as a predictive and prognostic marker for pancreatic ductal adenocarcinoma in Caucasians
-
Liu Q., Chen J., Mai B., Amos C., Killary A.M., Sen S., et al. A single-nucleotide polymorphism in tumor suppressor gene SEL1L as a predictive and prognostic marker for pancreatic ductal adenocarcinoma in Caucasians. Mol Carcinog 2012, 51(5):433-438.
-
(2012)
Mol Carcinog
, vol.51
, Issue.5
, pp. 433-438
-
-
Liu, Q.1
Chen, J.2
Mai, B.3
Amos, C.4
Killary, A.M.5
Sen, S.6
-
78
-
-
84864054515
-
SEL1L: an UPR response protein, a potential marker of colonic cell transformation
-
Ashktorab H., Green W., Finzi G., Sessa F., Nouraie M., Lee E.L., et al. SEL1L: an UPR response protein, a potential marker of colonic cell transformation. Dig Dis Sci 2012, 57(4):905-912.
-
(2012)
Dig Dis Sci
, vol.57
, Issue.4
, pp. 905-912
-
-
Ashktorab, H.1
Green, W.2
Finzi, G.3
Sessa, F.4
Nouraie, M.5
Lee, E.L.6
-
79
-
-
79956305479
-
MSEL-1L (suppressor/enhancer Lin12-like) protein levels influence murine neural stem cell self-renewal and lineage commitment
-
Cardano M., Diaferia G.R., Cattaneo M., Dessi S.S., Long Q., Conti L., et al. mSEL-1L (suppressor/enhancer Lin12-like) protein levels influence murine neural stem cell self-renewal and lineage commitment. J Biol Chem 2011, 286(21):18708-18719.
-
(2011)
J Biol Chem
, vol.286
, Issue.21
, pp. 18708-18719
-
-
Cardano, M.1
Diaferia, G.R.2
Cattaneo, M.3
Dessi, S.S.4
Long, Q.5
Conti, L.6
-
80
-
-
84893493393
-
Down-modulation of SEL1L: an unfolded protein response and endoplasmic reticulum-associated degradation protein, sensitizes glioma stem cells to the cytotoxic effect of valproic acid
-
Cattaneo M., Baronchelli S., Schiffer D., Mellai M., Caldera V., Saccani G.J., et al. Down-modulation of SEL1L: an unfolded protein response and endoplasmic reticulum-associated degradation protein, sensitizes glioma stem cells to the cytotoxic effect of valproic acid. J Biol Chem 2014, 289(5):2826-2838.
-
(2014)
J Biol Chem
, vol.289
, Issue.5
, pp. 2826-2838
-
-
Cattaneo, M.1
Baronchelli, S.2
Schiffer, D.3
Mellai, M.4
Caldera, V.5
Saccani, G.J.6
-
81
-
-
0037081182
-
SEL1L expression decreases breast tumor cell aggressiveness in vivo and in vitro
-
Orlandi R., Cattaneo M., Troglio F., Casalini P., Ronchini C., Menard S., et al. SEL1L expression decreases breast tumor cell aggressiveness in vivo and in vitro. Cancer Res 2002, 62(2):567-574.
-
(2002)
Cancer Res
, vol.62
, Issue.2
, pp. 567-574
-
-
Orlandi, R.1
Cattaneo, M.2
Troglio, F.3
Casalini, P.4
Ronchini, C.5
Menard, S.6
-
82
-
-
4444253793
-
SEL1L and squamous cell carcinoma of the esophagus
-
Granelli P., Cattaneo M., Ferrero S., Bottiglieri L., Bosari S., Fichera G., et al. SEL1L and squamous cell carcinoma of the esophagus. Clin Cancer Res 2004, 10(17):5857-5861.
-
(2004)
Clin Cancer Res
, vol.10
, Issue.17
, pp. 5857-5861
-
-
Granelli, P.1
Cattaneo, M.2
Ferrero, S.3
Bottiglieri, L.4
Bosari, S.5
Fichera, G.6
-
83
-
-
40249088336
-
OS-9 and GRP94 deliver mutant alpha1-antitrypsin to the Hrd1-SEL1L ubiquitin ligase complex for ERAD
-
Christianson J.C., Shaler T.A., Tyler R.E., Kopito RR. OS-9 and GRP94 deliver mutant alpha1-antitrypsin to the Hrd1-SEL1L ubiquitin ligase complex for ERAD. Nat Cell Biol 2008, 10(3):272-282.
-
(2008)
Nat Cell Biol
, vol.10
, Issue.3
, pp. 272-282
-
-
Christianson, J.C.1
Shaler, T.A.2
Tyler, R.E.3
Kopito, R.R.4
-
84
-
-
67650535999
-
Human OS-9: a lectin required for glycoprotein endoplasmic reticulum-associated degradation, recognizes mannose-trimmed N-glycans
-
Hosokawa N., Kamiya Y., Kamiya D., Kato K., Nagata K. Human OS-9: a lectin required for glycoprotein endoplasmic reticulum-associated degradation, recognizes mannose-trimmed N-glycans. J Biol Chem 2009, 284(25):17061-17068.
-
(2009)
J Biol Chem
, vol.284
, Issue.25
, pp. 17061-17068
-
-
Hosokawa, N.1
Kamiya, Y.2
Kamiya, D.3
Kato, K.4
Nagata, K.5
-
85
-
-
13944276440
-
OS-9 interacts with hypoxia-inducible factor 1alpha and prolyl hydroxylases to promote oxygen-dependent degradation of HIF-1alpha
-
Baek J.H., Mahon P.C., Oh J., Kelly B., Krishnamachary B., Pearson M., et al. OS-9 interacts with hypoxia-inducible factor 1alpha and prolyl hydroxylases to promote oxygen-dependent degradation of HIF-1alpha. Mol Cell 2005, 17(4):503-512.
-
(2005)
Mol Cell
, vol.17
, Issue.4
, pp. 503-512
-
-
Baek, J.H.1
Mahon, P.C.2
Oh, J.3
Kelly, B.4
Krishnamachary, B.5
Pearson, M.6
-
86
-
-
0035917313
-
2 sensing
-
2 sensing. Science 2001, 292(5516):464-468.
-
(2001)
Science
, vol.292
, Issue.5516
, pp. 464-468
-
-
Ivan, M.1
Kondo, K.2
Yang, H.3
Kim, W.4
Valiando, J.5
Ohh, M.6
-
87
-
-
78649962068
-
Novel metastasis-related gene CIM functions in the regulation of multiple cellular stress-response pathways
-
Yanagisawa K., Konishi H., Arima C., Tomida S., Takeuchi T., Shimada Y., et al. Novel metastasis-related gene CIM functions in the regulation of multiple cellular stress-response pathways. Cancer Res 2010, 70(23):9949-9958.
-
(2010)
Cancer Res
, vol.70
, Issue.23
, pp. 9949-9958
-
-
Yanagisawa, K.1
Konishi, H.2
Arima, C.3
Tomida, S.4
Takeuchi, T.5
Shimada, Y.6
-
88
-
-
84904999339
-
Selective inhibition of unfolded protein response induces apoptosis in pancreatic cancer cells
-
Chien W., Ding LW, Sun QY, Torres-Fernandez LA, Tan SZ, Xiao J., et al. Selective inhibition of unfolded protein response induces apoptosis in pancreatic cancer cells. Oncotarget 2014, 5(13):4881-4894.
-
(2014)
Oncotarget
, vol.5
, Issue.13
, pp. 4881-4894
-
-
Chien, W.1
Ding, LW2
Sun, QY3
Torres-Fernandez, LA4
Tan, SZ5
Xiao, J.6
-
89
-
-
79951857650
-
Unfolded protein response in cancer: the physician's perspective
-
Li X., Zhang K., Li Z. Unfolded protein response in cancer: the physician's perspective. J Hematol Oncol 2011, 4:8.
-
(2011)
J Hematol Oncol
, vol.4
, pp. 8
-
-
Li, X.1
Zhang, K.2
Li, Z.3
-
90
-
-
80054764086
-
Virus-tumor interactome screen reveals ER stress response can reprogram resistant cancers for oncolytic virus-triggered caspase-2 cell death
-
Mahoney D.J., Lefebvre C., Allan K., Brun J., Sanaei C.A., Baird S., et al. Virus-tumor interactome screen reveals ER stress response can reprogram resistant cancers for oncolytic virus-triggered caspase-2 cell death. Cancer Cell 2011, 20(4):443-456.
-
(2011)
Cancer Cell
, vol.20
, Issue.4
, pp. 443-456
-
-
Mahoney, D.J.1
Lefebvre, C.2
Allan, K.3
Brun, J.4
Sanaei, C.A.5
Baird, S.6
-
91
-
-
84900295626
-
Endoplasmic reticulum stress: its role in disease and novel prospects for therapy
-
Schonthal A.H. Endoplasmic reticulum stress: its role in disease and novel prospects for therapy. Scientifica (Cairo) 2012, 2012:857516.
-
(2012)
Scientifica (Cairo)
, vol.2012
, pp. 857516
-
-
Schonthal, A.H.1
-
92
-
-
78649742954
-
The ERAD inhibitor Eeyarestatin I is a bifunctional compound with a membrane-binding domain and a p97/VCP inhibitory group
-
Wang Q., Shinkre B.A., Lee J.G., Weniger M.A., Liu Y., Chen W., et al. The ERAD inhibitor Eeyarestatin I is a bifunctional compound with a membrane-binding domain and a p97/VCP inhibitory group. PLoS ONE 2010, 5(11):e15479.
-
(2010)
PLoS ONE
, vol.5
, Issue.11
, pp. e15479
-
-
Wang, Q.1
Shinkre, B.A.2
Lee, J.G.3
Weniger, M.A.4
Liu, Y.5
Chen, W.6
-
93
-
-
84875134606
-
Curability of multiple myeloma
-
Alexanian R., Delasalle K., Wang M., Thomas S., Weber D. Curability of multiple myeloma. Bone Marrow Res 2012, 2012:916479.
-
(2012)
Bone Marrow Res
, vol.2012
, pp. 916479
-
-
Alexanian, R.1
Delasalle, K.2
Wang, M.3
Thomas, S.4
Weber, D.5
-
94
-
-
84883625365
-
Xbp1s-negative tumor B cells and pre-plasmablasts mediate therapeutic proteasome inhibitor resistance in multiple myeloma
-
Leung-Hagesteijn C, Erdmann N., Cheung G., Keats J.J., Stewart A.K., Reece D.E., et al. Xbp1s-negative tumor B cells and pre-plasmablasts mediate therapeutic proteasome inhibitor resistance in multiple myeloma. Cancer Cell 2013, 24(3):289-304.
-
(2013)
Cancer Cell
, vol.24
, Issue.3
, pp. 289-304
-
-
Leung-Hagesteijn, C.1
Erdmann, N.2
Cheung, G.3
Keats, J.J.4
Stewart, A.K.5
Reece, D.E.6
-
95
-
-
84870808965
-
Nonmuscle myosin IIB links cytoskeleton to IRE1alpha signaling during ER stress
-
He Y., Beatty A., Han X., Ji Y., Ma X., Adelstein R.S., et al. Nonmuscle myosin IIB links cytoskeleton to IRE1alpha signaling during ER stress. Dev Cell 2012, 23(6):1141-1152.
-
(2012)
Dev Cell
, vol.23
, Issue.6
, pp. 1141-1152
-
-
He, Y.1
Beatty, A.2
Han, X.3
Ji, Y.4
Ma, X.5
Adelstein, R.S.6
-
96
-
-
66049108823
-
The IRE1alpha-XBP1 pathway of the unfolded protein response is required for adipogenesis
-
Sha H., He Y., Chen H., Wang C., Zenno A., Shi H., et al. The IRE1alpha-XBP1 pathway of the unfolded protein response is required for adipogenesis. Cell Metab 2009, 9(6):556-564.
-
(2009)
Cell Metab
, vol.9
, Issue.6
, pp. 556-564
-
-
Sha, H.1
He, Y.2
Chen, H.3
Wang, C.4
Zenno, A.5
Shi, H.6
-
97
-
-
77955342864
-
A Phos-tag-based approach reveals the extent of physiological endoplasmic reticulum stress
-
Yang L., Xue Z., He Y., Sun S., Chen H., Qi L. A Phos-tag-based approach reveals the extent of physiological endoplasmic reticulum stress. PLoS ONE 2010, 5(7):e11621.
-
(2010)
PLoS ONE
, vol.5
, Issue.7
, pp. e11621
-
-
Yang, L.1
Xue, Z.2
He, Y.3
Sun, S.4
Chen, H.5
Qi, L.6
-
98
-
-
50449086728
-
Bortezomib plus melphalan and prednisone for initial treatment of multiple myeloma
-
San Miguel J.F., Schlag R., Khuageva N.K., Dimopoulos M.A., Shpilberg O., Kropff M., et al. Bortezomib plus melphalan and prednisone for initial treatment of multiple myeloma. N Engl J Med 2008, 359:906-917.
-
(2008)
N Engl J Med
, vol.359
, pp. 906-917
-
-
San Miguel, J.F.1
Schlag, R.2
Khuageva, N.K.3
Dimopoulos, M.A.4
Shpilberg, O.5
Kropff, M.6
-
99
-
-
34247265390
-
The HIV protease inhibitor nelfinavir downregulates Akt phosphorylation by inhibiting proteasomal activity and inducing the unfolded protein response
-
Gupta A.K., Li B., Cerniglia G.J., Ahmed M.S., Hahn S.M., Maity A. The HIV protease inhibitor nelfinavir downregulates Akt phosphorylation by inhibiting proteasomal activity and inducing the unfolded protein response. Neoplasia 2007, 9:271-278.
-
(2007)
Neoplasia
, vol.9
, pp. 271-278
-
-
Gupta, A.K.1
Li, B.2
Cerniglia, G.J.3
Ahmed, M.S.4
Hahn, S.M.5
Maity, A.6
-
100
-
-
70849133790
-
Eeyarestatin I inhibits Sec61-mediated protein translocation at the endoplasmic reticulum
-
Cross B.C., McKibbin C., Callan A.C., Roboti P., Piacenti M., Rabu C., et al. Eeyarestatin I inhibits Sec61-mediated protein translocation at the endoplasmic reticulum. J Cell Sci 2009, 122:4393-4400.
-
(2009)
J Cell Sci
, vol.122
, pp. 4393-4400
-
-
Cross, B.C.1
McKibbin, C.2
Callan, A.C.3
Roboti, P.4
Piacenti, M.5
Rabu, C.6
-
101
-
-
84864580657
-
Antiviral activity of a small molecule deubiquitinase inhibitor occurs via induction of the unfolded protein response
-
Perry J.W., Ahmed M., Chang K.O., Donato N.J., Showalter H.D., Wobus C.E. Antiviral activity of a small molecule deubiquitinase inhibitor occurs via induction of the unfolded protein response. PLoS Pathog 2012, 8:e1002783.
-
(2012)
PLoS Pathog
, vol.8
, pp. e1002783
-
-
Perry, J.W.1
Ahmed, M.2
Chang, K.O.3
Donato, N.J.4
Showalter, H.D.5
Wobus, C.E.6
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