ER stress transcription factor Xbp1 suppresses intestinal tumorigenesis and directs intestinal stem cells

Journal of Experimental Medicine

Volumn 210, Issue 10, 2013, Pages 2041-2056

  Niederreiter, Lukas ^a   Fritz, Teresa M J ^b   Adolph, Timon E ^a   Krismer, Anna Maria ^b   Offner, Felix A ^c   Tschurtschenthaler, Markus ^b   Flak, Magdalena B ^d   Hosomi, Shuhei ^d   Tomczak, Michal F ^d   Kaneider, Nicole C ^a,b   Sarcevic, Edina ^c   Kempster, Sarah L ^a   Raine, Tim ^a   Esser, Daniela ^e   Rosenstiel, Philip ^e   Kohno, Kenji ^f   Iwawaki, Takao ^g,h   Tilg, Herbert ^b   Blumberg, Richard S ^d   Kaser, Arthur ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^c Academic Teaching Hospital Feldkirch   (Australia)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

^e UNIVERSITY OF KIEL   (Germany)

^f NARA INSTITUTE OF SCIENCE AND TECHNOLOGY   (Japan)

^g GUNMA UNIVERSITY   (Japan)

^h INST OF PHYS AND CHEMICAL RESEARCH   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

STAT3 PROTEIN; X BOX BINDING PROTEIN 1;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; COLON TUMOR; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; INTESTINAL STEM CELL; INTESTINE CELL; INTESTINE EPITHELIUM; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; STEM CELL;

ANIMALS; AUTOCRINE COMMUNICATION; CELL TRANSFORMATION, NEOPLASTIC; COLORECTAL NEOPLASMS; DNA-BINDING PROTEINS; ENDOPLASMIC RETICULUM STRESS; ENDORIBONUCLEASES; ENZYME ACTIVATION; GENE DELETION; GENES, APC; INTERLEUKIN-11; INTERLEUKIN-6; INTESTINAL MUCOSA; INTESTINES; JANUS KINASE 1; MAP KINASE KINASE 4; MICE; MICE, KNOCKOUT; NF-KAPPA B; PROTEIN-SERINE-THREONINE KINASES; STAT3 TRANSCRIPTION FACTOR; STEM CELLS; TRANSCRIPTION FACTORS; TUMOR BURDEN;

EID: 84885437087     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20122341     Document Type: Article

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