Activation of the endoplasmic reticulum stress pathway is associated with survival of myeloma cells

Leukemia and Lymphoma

Volumn 47, Issue 3, 2006, Pages 531-539

  Nakamura, Miki ^a   Gotoh, Tomomi ^a   Okuno, Yutaka ^a   Tatetsu, Hiro ^a   Sonoki, Takashi ^a   Uneda, Shima ^a   Mori, Masataka ^a   Mitsuya, Hiroaki ^a   Hata, Hiroyuki ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

Author keywords

Apoptosis; Endoplasmic reticulum stress; Multiple myeloma; XBP 1

Indexed keywords

CASPASE 3; CHAPERONE; M PROTEIN; THAPSIGARGIN; TRANSCRIPTION FACTOR;

ADULT; AGED; APOPTOSIS; ARTICLE; CELL FUNCTION; CELL ISOLATION; CELL LINE; CELL SURVIVAL; CELLULAR DISTRIBUTION; CLINICAL ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENDOPLASMIC RETICULUM; FEMALE; GENETIC HETEROGENEITY; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; MYELOMA CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN SYNTHESIS; REGULATORY MECHANISM; STRESS; UPREGULATION;

ADULT; AGED; AGED, 80 AND OVER; APOPTOSIS; CELL LINE, TUMOR; CELL SURVIVAL; DNA-BINDING PROTEINS; DRUG RESISTANCE, NEOPLASM; ENDOPLASMIC RETICULUM; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MALE; MIDDLE AGED; MOLECULAR CHAPERONES; MULTIPLE MYELOMA; NUCLEAR PROTEINS; OXIDATIVE STRESS; PROGNOSIS; RETROSPECTIVE STUDIES; RNA, MESSENGER; SURVIVAL ANALYSIS; THAPSIGARGIN;

EID: 30844472027     PISSN: 10428194     EISSN: None     Source Type: Journal    
DOI: 10.1080/10428190500312196     Document Type: Article

References (42)

1. Ribas, C and Colleoni, G. (2003) Advances in the treatment of multiple myeloma: The role of thalidomide Leuk Lymphoma, 44, pp. 291-298.
2. Sirohi, B and Powles, R. (2004) Multiple myeloma Lancet, 363, pp. 875-887.
3. Mitsiades, N and Mitsiades, C and Richardson, P and Poulaki, V and Tai, Y and Chauhan, D and (2003) The proteasome inhibitor PS-341 potentiates sensitivity of multiple myeloma cells to conventional chemotherapeutic agents: Therapeutic applications Blood, 101, pp. 2377-2380.
4. Shapiro-Shelef, M and Calame, K. (2004) Plasma cell differentiation and multiple myeloma Curr Opin Immunol, 16, pp. 226-234.
5. Oyadomari, S and Araki, E and Mori, M. (2002) Endoplasmic reticulum stress-mediated apoptosis in pancreatic beta-cells Apoptosis, 7, pp. 335-345.
6. Rutkowski, D and Kaufman, R. (2003) All roads lead to ATF4 Dev in Cell, 4, pp. 442-444.
7. Rutkowski, D and Kaufman, R. (2004) A trip to the ER: Coping with stress Trends in Cell Biol, 14, pp. 20-28.
8. Ferri, K and Kroemer, G. (2001) Organelle-specific initiation of cell death pathways Nat Cell Biol, 3, pp. E255-E263.
9. Yoshida, H and Matsui, T and Hosokawa, N and Kaufman, R and Nagata, K and Mori, K. (2003) A time-dependent phase shift in the mammalian unfolded protein response Dev in Cell, 4, pp. 265-271.
10. Lee, K and Tirasophon, W and Shen, X and Michalak, M and Prywes, R and Okada, T and (2002) IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response Genes Devel, 16, pp. 452-466.
11. Oyadomari, S and Mori, M. (2004) Roles of CHOP/GADD153 in endoplasmic reticulum stress Cell Death Difference, 11, pp. 381-389.
12. Iwakoshi, N and Lee, A and Glimcher, L. (2003) The X-box binding protein-1 transcription factor is required for plasma cell differentiation and the unfolded protein response Immunol Rev, 194, pp. 29-38.
13. Melnick, J and Aviel, S and Argon, Y. (1992) The endoplasmic reticulum stress protein GRP94, in addition to BiP, associates with unassembled immunoglobulin chains J Biol Chem, 267, pp. 21303-21306.
14. Yoshida, H and Matsui, T and Yamamoto, A and Okada, T and Mori, K. (2001) XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor Cell, 107, pp. 881-891.
15. Shen, X and Ellis, R and Lee, K and Liu, C and Yang, K and Solomon, A and (2001) Complementary signaling pathways regulate the unfolded protein response and are required for C. elegans development Cell, 107, pp. 893-903.
16. Calfon, M and Zeng, H and Urano, F and Till, J and Hubbard, S and Harding, H and (2002) IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA Nature, 415, pp. 92-96.
17. Reimold, A and Iwakoshi, N and Manis, J and Vallabhajosyula, P and Szomolanyi-Tsuda, E and Gravallese, E and (2001) Plasma cell differentiation requires the transcription factor XBP-1 Nature, 412, pp. 300-307.
18. Iwakoshi, N and Lee, A and Vallabhajosyula, P and Otipoby, K and Rajewsky, K and Glimcher, L. (2003) Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1 Nat Immunol, 4, pp. 321-329.
19. Munshi, N and Hideshima, T and Carrasco, D and Shammas, M and Auclair, D and Davies, F and (2004) Identification of genes modulated in multiple myeloma using genetically identical twin samples Blood, 103, pp. 1799-1806.
20. Lee, A and Iwakoshi, N and Anderson, K and Glimcher, L. (2003) Proteasome inhibitors disrupt the unfolded protein response in myeloma cells Proc Natl Acad Sci USA, 100, pp. 9946-9951.
21. Durie, B and Salmon, S. (1975) A clinical staging system for multiple myeloma. Correlation of measured myeloma cell mass with presenting clinical features, response to treatment, and survival Cancer, 36, pp. 842-854.
22. Uneda, S and Hata, H and Matsuno, F and Harada, N and Mitsuya, Y and Kawano, F and Mitsuya, H. (2003) Macrophage inflammatory protein-1 alpha is produced by human multiple myeloma (MM) cells and its expression correlates with bone lesions in patients with MM Br J Haematol, 120, pp. 53-55.
23. Ohtsuki, T and Yawata, Y and Wada, H and Sugihara, T and Mori, M and Namba, M. (1989) Two human myeloma cell lines, amylase-producing KMS-12-PE and amylase-non-producing KMS-12-BM, were established from a patient, having the same chromosome marker, t(11;14)(q13;q32) Br J Haematol, 73, pp. 199-204.
24. Ikeyama, S and Nakagawa, S and Arakawa, M and Sugino, H and Kakinuma, A. (1986) Purification and characterization of IgE produced by human myeloma cell line, U266 Mol Immunol, 23, pp. 159-167.
25. Matsuoka, Y and Moore, G. and Yagi, Y and Pressman, D. (1967) Production of free light chains of immunoglobulin by a hematopoietic cell line derived from a patient with multiple myeloma Proceedings of the Society of Exp Biol Med, 125, pp. 1246.
26. Hata, H and Matsuzaki, H and Sonoki, T and Takemoto, S and Kuribayashi, N and Nagasaki, A and Takatsuki, K. (1994) Establishment of a CD45-positive immature plasma cell line from an aggressive multiple myeloma with high serum lactate dehydrogenase Leukemia, 8, pp. 1768-1773.
27. Togawa, A and Inoue, N and Miyamoto, K and Hyodo, H and Namba, M. (1982) Establishment and characterization of a human myeloma cell line (KMM-1) Int J Cancer, 29, pp. 495-500.
28. Epstein, M and Achong, B and Barr, Y and Zajac, B and Henle, G and Henle, W. (1966) Morphological and virological investigations on cultured Burkitt tumor lymphoblasts (strain Raji) J Nat Cancer Inst, 37, pp. 547-559.
29. Sonoki, T and Matsuzaki, H and Miyamoto, K and Taniwaki, M and Yoshino, T and Hata, H and (1995) Establishment of the novel B acute lymphoblastic leukemia (FAB L3) cell line KHM-10B with a 13q34 abnormality and constitutive expression of c-myc and max during cell cycle Leukemia, 9, pp. 2093-2099.
30. Collins, S and Ruscetti, F and Gallagher, R and Gallo, R. (1978) Terminal differentiation of human promyelocytic leukemia cells induced by dimethyl sulfoxide and other polar compounds Proc Nat Acad Sci USA, 75, pp. 2458-2462.
31. Chomczynski, P. (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction Analyt Biochemis, 162, pp. 156-159.
32. Gotoh, T and Mori, M. (1999) Arginase II downregulates nitric oxide (NO) production and prevents NO-mediated apoptosis in murine macrophage-derived RAW 264.7 cells J Cell Biol, 144, pp. 427-434.
33. Reddy, R and Mao, C and Baumeister, P and Austin, R and Kaufman, R and Lee, A. (2003) Endoplasmic reticulum chaperone protein GRP78 protects cells from apoptosis induced by topoisomerase inhibitors: Role of ATP binding site in suppression of caspase-7 activation J Biolog Chem, 278, pp. 20915-20924.
34. Ma, Y and Hendershot, L. (2003) The stressful road to antibody secretion Nat Immunol, 4, pp. 310-311.
35. Matsumoto, M and Minami, M and Takeda, K and Sakao, Y and Akira, S. (1996) Ectopic expression of CHOP (GADD153) induces apoptosis in M1 myeloblastic leukemia cells FEBS Letters, 395, pp. 143-147.
36. McCullough, K and Martindale, J and Klotz, L and Aw, T and Holbrook, N. (2001) Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state Mol Cell Biol, 21, pp. 1249-1259.
37. Anether, G and Tinhofer, I and Senfter, M and Greil, R. (2003) Tetrocarcin-A - induced ER stress mediates apoptosis in B-CLL cells via a Bcl-2-independent pathway Blood, 101, pp. 4561-4568.
38. Wen, X and Stewart, A and Sooknanan, R and Henderson, G and Hawley, T and Reimold, A and (1999) Identification of c-myc promoter-binding protein and X-box binding protein 1 as interleukin-6 target genes in human multiple myeloma cells Int J Oncol, 15, pp. 173-178.
39. Anagnostopoulos, A and Gika, D and Hamilos, G and Zervas, K and Zomas, A and Pouli, A and (2004) Treatment of relapsed/refractory multiple myeloma with thalidomide-based regimens: Identification of prognostic factors Leuk Lymphoma, 45, pp. 2275-2279.
40. Harding, H and Zhang, Y and Zeng, H and Novoa, I and Lu, P and Calfon, M and (2003) An integrated stress response regulates amino acid metabolism and resistance to oxidative stress Mol Cell, 11, pp. 619-633.
41. Jiang, H and Wek, S and McGrath, B and Lu, D and Hai, T and Harding, H and (2004) Activating transcription factor 3 is integral to the eukaryotic initiation factor 2 kinase stress response Mol Cell Biol, 24, pp. 1365-1377.
42. Okada, T and Haze, K and Nadanaka, S and Yoshida, H and Seidah, N and Hirano, Y and (2003) A serine protease inhibitor prevents endoplasmic reticulum stress-induced cleavage but not transport of the membrane-bound transcription factor ATF6 J Biol Chem, 278, pp. 31024-31032.