RNA surveillance is required for endoplasmic reticulum homeostasis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 21, 2012, Pages 8079-8084

  Sakaki, Kenjiro ^a,b   Yoshina, Sawako ^b,c   Shen, Xiaohua ^d   Han, Jaeseok ^a,e   DeSantis, Melinda R ^a   Xiong, Mon ^a   Mitani, Shohei ^b,c   Kaufman, Randal J ^a,e  

^a UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^b TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^d Tsinghua University   (China)

^e BURNHAM INSTITUTE   (United States)

Author keywords

Endoplasmic reticulum quality control; Premature termination codons

Indexed keywords

MESSENGER RNA;

ANIMAL CELL; ARTICLE; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; DEGENERATION; DEVELOPMENTAL GENE; ENDOPLASMIC RETICULUM STRESS; EXOS 3 GENE; EXOSOME; F48E8 6 GENE; GENE FUNCTION; GENE IDENTIFICATION; GENE PRODUCT; GENETIC SCREENING; HOMEOSTASIS; INTESTINE MALFORMATION; IRE1 GENE; LARVAL DEVELOPMENT; MAMMAL CELL; MUTANT; NONHUMAN; NONSENSE MEDIATED MRNA DECAY; NULL ALLELE; PRIORITY JOURNAL; RNA INTERFERENCE; SMG 1 GENE; SMG 4 GENE; SMG 6 GENE; UNFOLDED PROTEIN RESPONSE; WILD TYPE;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CELL LINE, TRANSFORMED; CELL SURVIVAL; CODON, NONSENSE; EIF-2 KINASE; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; HELA CELLS; HEPATOCYTES; HOMEOSTASIS; HUMANS; LARVA; MICE; NUCLEAR PROTEINS; PROTEIN-SERINE-THREONINE KINASES; PROTEOSTASIS DEFICIENCIES; RNA; RNA INTERFERENCE; TELOMERASE; UNFOLDED PROTEIN RESPONSE;

CAENORHABDITIS ELEGANS; MAMMALIA; METAZOA;

EID: 84861434815     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1110589109     Document Type: Article

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