Change in heat capacity accurately predicts vibrational coupling in enzyme catalyzed reactions

FEBS Letters

Volumn 589, Issue 17, 2015, Pages 2200-2206

  Arcus, Vickery L ^a   Pudney, Christopher R ^b  

^a UNIVERSITY OF WAIKATO   (New Zealand)

^b University of Bath   (United Kingdom)

Author keywords

Catalysis; Enzyme dynamics; Heat capacity; Promoting motion; Vibrational coupling

Indexed keywords

ACCURACY; ARTICLE; CATALYSIS; CHEMICAL PARAMETERS; CHEMICAL PHENOMENA; CHEMICAL REACTION; CONTROLLED STUDY; DEUTERIUM HYDROGEN EXCHANGE; ENZYME ACTIVE SITE; ENZYME MECHANISM; ENZYME SUBSTRATE COMPLEX; HEAT CAPACITY; HYDROGEN BOND; HYDROGEN TRANSFER REACTION; KINETIC ISOTOPE EFFECT; MACROMOLECULAR RATE THEORY; MATHEMATICAL MODEL; MOLECULAR DYNAMICS; OBSERVED RATE CONSTANT; PREDICTIVE VALUE; PRIORITY JOURNAL; SENSITIVITY ANALYSIS; TEMPERATURE DEPENDENCE; TEMPERATURE RELATED PHENOMENA; THEORY; VIBRATIONAL COUPLING; ALGORITHM; CHEMICAL MODEL; CHEMISTRY; ENZYME SPECIFICITY; HEAT; KINETICS; METABOLISM; PH; THERMODYNAMICS;

ENZYME; ISOTOPE;

ALGORITHMS; CATALYSIS; ENZYMES; HOT TEMPERATURE; HYDROGEN-ION CONCENTRATION; ISOTOPES; KINETICS; MODELS, CHEMICAL; SUBSTRATE SPECIFICITY; THERMODYNAMICS;

EID: 84938118039     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2015.06.042     Document Type: Article

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