Enzyme structure and dynamics affect hydrogen tunneling: The impact of a remote side chain (I553) in soybean lipoxygenase-1

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 4, 2008, Pages 1146-1151

  Meyer, Matthew P ^a,c   Tomchick, Diana R ^b   Klinman, Judith P ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Hydrogenic wave function overlap; Protein dynamics

Indexed keywords

HYDROGEN; LIPOOXYGENASE 1; LIPOXYGENASE; UNCLASSIFIED DRUG; IRON; ISOLEUCINE; PROTEIN SUBUNIT; VEGETABLE PROTEIN;

CATALYSIS; CONFERENCE PAPER; ENZYME ACTIVE SITE; ENZYME DEGRADATION; ENZYME KINETICS; ENZYME STRUCTURE; HYDROPHOBICITY; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN FUNCTION; SOYBEAN; STRUCTURE ANALYSIS; X RAY ANALYSIS; AMINO ACID SUBSTITUTION; ARTICLE; BINDING SITE; CHEMISTRY; ENZYMOLOGY; GENETICS; KINETICS; METABOLISM; THERMODYNAMICS; X RAY CRYSTALLOGRAPHY;

GLYCINE MAX;

AMINO ACID SUBSTITUTION; BINDING SITES; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; HYDROGEN; HYDROPHOBICITY; IRON; ISOLEUCINE; KINETICS; LIPOXYGENASE; PLANT PROTEINS; PROTEIN SUBUNITS; SOYBEANS; THERMODYNAMICS;

EID: 39549094013     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0710643105     Document Type: Article

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