How does pressure affect barrier compression and isotope effects in an enzymatic hydrogen tunneling reaction?

Angewandte Chemie - International Edition

Volumn 50, Issue 9, 2011, Pages 2129-2132

  Johannissen, Linus O ^a   Scrutton, Nigel S ^b   Sutcliffe, Michael J ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

compressive modes; enzyme catalysis; H tunneling; kinetic isotope effect; promoting vibrations

Indexed keywords

COMPRESSIVE MODE; ENZYME CATALYSIS; H-TUNNELING; KINETIC ISOTOPE EFFECT; PROMOTING VIBRATIONS;

AMIDES; CARRIER MOBILITY; CATALYSIS; ENZYMES; MOLECULAR DYNAMICS; REACTION KINETICS;

ISOTOPES;

BACTERIAL PROTEIN; FLAVINE MONONUCLEOTIDE; HYDROGEN; MORPHINONE REDUCTASE; NICOTINAMIDE ADENINE DINUCLEOTIDE; OXIDOREDUCTASE;

ARTICLE; BIOCATALYSIS; CHEMISTRY; KINETICS; METABOLISM; MOLECULAR DYNAMICS; PRESSURE; TEMPERATURE; THERMODYNAMICS; VIBRATION;

BACTERIAL PROTEINS; BIOCATALYSIS; FLAVIN MONONUCLEOTIDE; HYDROGEN; KINETICS; MOLECULAR DYNAMICS SIMULATION; NAD; OXIDOREDUCTASES; PRESSURE; TEMPERATURE; THERMODYNAMICS; VIBRATION;

EID: 79951913324     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201006668     Document Type: Article

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