-
2
-
-
0003974187
-
-
Geneva, Switzerland: World Health Organization
-
Fenner F, Henderson DA, Arita I, Jezek Z, Ladnyi ID, World Health Organization. 1988 Smallpox and its eradication. Geneva, Switzerland: World Health Organization.
-
(1988)
Smallpox and its eradication
-
-
Fenner, F.1
Henderson, D.A.2
Arita, I.3
Jezek, Z.4
Ladnyi, I.D.5
World Health Organization6
-
5
-
-
0036188743
-
Emil von Behring and serum therapy
-
Winau F, Winau R. 2002 Emil von Behring and serum therapy. Microbes Infect. 4, 185-188. (doi:10.1016/S1286-4579(01)01526-X)
-
(2002)
Microbes Infect
, vol.4
, pp. 185-188
-
-
Winau, F.1
Winau, R.2
-
6
-
-
0344037339
-
Reshaping a human monoclonal antibody to inhibit human respiratory syncytial virus infection in vivo
-
Tempest PR, Bremner P, Lambert M, Taylor G, Furze JM, Carr FJ, Harris WJ. 1991 Reshaping a human monoclonal antibody to inhibit human respiratory syncytial virus infection in vivo. Biotechnology 9, 266-271. (doi:10.1038/nbt0391-266)
-
(1991)
Biotechnology
, vol.9
, pp. 266-271
-
-
Tempest, P.R.1
Bremner, P.2
Lambert, M.3
Taylor, G.4
Furze, J.M.5
Carr, F.J.6
Harris, W.J.7
-
7
-
-
0031683919
-
Palivizumab, a humanized respiratory syncytial virus monoclonal antibody, reduces hospitalization from respiratory syncytial virus infection in high-risk infants
-
The IMpact-RSV Study Group. 1998 Palivizumab, a humanized respiratory syncytial virus monoclonal antibody, reduces hospitalization from respiratory syncytial virus infection in high-risk infants. Pediatrics 102, 531-537. (doi:10.1542/peds. 102.3.531)
-
(1998)
Pediatrics
, vol.102
, pp. 531-537
-
-
-
8
-
-
0345337254
-
Rituximab chimeric anti- CD20 monoclonal antibody therapy for relapsed indolent lymphoma: Half of patients respond to a four-dose treatment program
-
McLaughlin P et al. 1998 Rituximab chimeric anti- CD20 monoclonal antibody therapy for relapsed indolent lymphoma: half of patients respond to a four-dose treatment program. J. Clin. Oncol. 16, 2825-2833.
-
(1998)
J. Clin. Oncol
, vol.16
, pp. 2825-2833
-
-
McLaughlin, P.1
-
9
-
-
0035869407
-
Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2
-
Slamon DJ et al. 2001 Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. N. Engl. J. Med. 344, 783-792. (doi:10.1056/NEJM2001031 53441101)
-
(2001)
N. Engl. J. Med
, vol.344
, pp. 783-792
-
-
Slamon, D.J.1
-
10
-
-
0037092951
-
Therapeutic role of alemtuzumab (Campath-1H) in patients who have failed fludarabine: Results of a large international study
-
Keating MJ et al. 2002 Therapeutic role of alemtuzumab (Campath-1H) in patients who have failed fludarabine: results of a large international study. Blood 99, 3554-3561. (doi:10.1182/blood.V99.10.3554)
-
(2002)
Blood
, vol.99
, pp. 3554-3561
-
-
Keating, M.J.1
-
11
-
-
54949085398
-
K-ras mutations and benefit from cetuximab in advanced colorectal cancer
-
Karapetis CS et al. 2008 K-ras mutations and benefit from cetuximab in advanced colorectal cancer. N. Engl. J. Med. 359, 1757-1765. (doi:10.1056/ NEJMoa0804385)
-
(2008)
N. Engl. J. Med
, vol.359
, pp. 1757-1765
-
-
Karapetis, C.S.1
-
12
-
-
77949544945
-
Effectiveness and safety of bevacizumab for unresectable non-small-cell lung cancer: A metaanalysis
-
Yang K, Wang Y-J, Chen X-R, Chen H-N. 2010 Effectiveness and safety of bevacizumab for unresectable non-small-cell lung cancer: a metaanalysis. Clin. Drug Invest. 30, 229-241. (doi:10. 2165/11532260-000000000-00000)
-
(2010)
Clin. Drug Invest
, vol.30
, pp. 229-241
-
-
Yang, K.1
Wang, Y.-J.2
Chen, X.-R.3
Chen, H.-N.4
-
13
-
-
0035320525
-
Autoimmunity versus horror autotoxicus: The struggle for recognition
-
Silverstein AM. 2001 Autoimmunity versus horror autotoxicus: the struggle for recognition. Nat. Immunol. 2, 279-281. (doi:10.1038/86280)
-
(2001)
Nat. Immunol
, vol.2
, pp. 279-281
-
-
Silverstein, A.M.1
-
14
-
-
0034892128
-
Autoimmune disease: Why and where it occurs
-
Marrack P, Kappler J, Kotzin BL. 2001 Autoimmune disease: why and where it occurs. Nat. Med. 7, 899-905. (doi:10.1038/90935)
-
(2001)
Nat. Med
, vol.7
, pp. 899-905
-
-
Marrack, P.1
Kappler, J.2
Kotzin, B.L.3
-
15
-
-
0018184359
-
Detection and properties of TSH-binding inhibitor immunoglobulins in patients with Graves' disease and Hashimoto's thyroiditis
-
Endo K, Kasagi K, Konishi J, Ikekubo K, Okuno T, Takeda Y, Mori T, Torizuka K. 1978 Detection and properties of TSH-binding inhibitor immunoglobulins in patients with Graves' disease and Hashimoto's thyroiditis. J. Clin. Endocrinol. Metab. 46, 734-739. (doi:10.1210/jcem-46-5-734)
-
(1978)
J. Clin. Endocrinol. Metab
, vol.46
, pp. 734-739
-
-
Endo, K.1
Kasagi, K.2
Konishi, J.3
Ikekubo, K.4
Okuno, T.5
Takeda, Y.6
Mori, T.7
Torizuka, K.8
-
16
-
-
0013964845
-
Deoxybonucleic acid (DNA) and antibodies to DNA in the serum of patients with systemic lupus erythematosus
-
Tan EM, Schur PH, Carr RI, Kunkel HG. 1966 Deoxybonucleic acid (DNA) and antibodies to DNA in the serum of patients with systemic lupus erythematosus. J. Clin. Invest. 45, 1732-1740. (doi:10.1172/JCI105479)
-
(1966)
J. Clin. Invest
, vol.45
, pp. 1732-1740
-
-
Tan, E.M.1
Schur, P.H.2
Carr, R.I.3
Kunkel, H.G.4
-
17
-
-
0019813834
-
Ro (SSA) and La (SSB) antibodies
-
Alexander EL, Provost TT. 1981 Ro (SSA) and La (SSB) antibodies. Semin. Immunopathol. 4, 253-273. (doi:10.1007/BF01892181)
-
(1981)
Semin. Immunopathol
, vol.4
, pp. 253-273
-
-
Alexander, E.L.1
Provost, T.T.2
-
18
-
-
0037211477
-
Enterovirus infections are associated with the induction of b-cell autoimmunity in a prospective birth cohort study
-
Salminen K et al. 2003 Enterovirus infections are associated with the induction of b-cell autoimmunity in a prospective birth cohort study. J. Med. Virol. 69, 91-98. (doi:10.1002/jmv.10260)
-
(2003)
J. Med. Virol
, vol.69
, pp. 91-98
-
-
Salminen, K.1
-
19
-
-
34948879087
-
Viral infection can induce the production of autoantibodies
-
Barzilai O, Ram M, Shoenfeld Y. 2007 Viral infection can induce the production of autoantibodies. Curr. Opin. Rheumatol. 19, 636-643. (doi:10.1097/BOR. 0b013e3282f0ad25)
-
(2007)
Curr. Opin. Rheumatol
, vol.19
, pp. 636-643
-
-
Barzilai, O.1
Ram, M.2
Shoenfeld, Y.3
-
20
-
-
43249119095
-
Defining the role of the MHC in autoimmunity: A review and pooled analysis
-
Fernando MMA, Stevens CR, Walsh EC, De Jager PL, Goyette P, Plenge RM, Vyse TJ, Rioux JD. 2008 Defining the role of the MHC in autoimmunity: a review and pooled analysis. PLoS Genet. Public Libr. Sci. 4, e1000024. (doi:10.1371/journal.pgen.1000024)
-
(2008)
PLoS Genet. Public Libr. Sci
, vol.4
-
-
Fernando, M.M.A.1
Stevens, C.R.2
Walsh, E.C.3
De Jager, P.L.4
Goyette, P.5
Plenge, R.M.6
Vyse, T.J.7
Rioux, J.D.8
-
21
-
-
34249950588
-
Dissecting the neutralizing antibody specificities of broadly neutralizing sera from human immunodeficiency virus type 1- infected donors
-
Dhillon AK et al. 2007 Dissecting the neutralizing antibody specificities of broadly neutralizing sera from human immunodeficiency virus type 1- infected donors. J. Virol. 81, 6548-6562. (doi:10. 1128/JVI.02749-06)
-
(2007)
J. Virol
, vol.81
, pp. 6548-6562
-
-
Dhillon, A.K.1
-
22
-
-
34948854718
-
Broad HIV-1 neutralization mediated by CD4-binding site antibodies
-
Li Y et al. 2007 Broad HIV-1 neutralization mediated by CD4-binding site antibodies. Nat. Med. 13, 1032-1034. (doi:10.1038/nm1624)
-
(2007)
Nat. Med
, vol.13
, pp. 1032-1034
-
-
Li, Y.1
-
23
-
-
56449131391
-
Profiling the specificity of neutralizing antibodies in a large panel of plasmas from patients chronically infected with human immunodeficiency virus type 1 subtypes B and C
-
Binley JM et al. 2008 Profiling the specificity of neutralizing antibodies in a large panel of plasmas from patients chronically infected with human immunodeficiency virus type 1 subtypes B and C. J. Virol. 82, 11 651-11 668. (doi:10.1128/JVI. 01762-08)
-
(2008)
J. Virol
, vol.82
, pp. 11 651-11 668
-
-
Binley, J.M.1
-
24
-
-
78651488739
-
Broadly cross-reactive antibodies dominate the human B cell response against 2009 pandemic H1N1 influenza virus infection
-
Wrammert J et al. 2011 Broadly cross-reactive antibodies dominate the human B cell response against 2009 pandemic H1N1 influenza virus infection. J. Exp. Med. 208, 181-193. (doi:10.1084/ jem.20101352)
-
(2011)
J. Exp. Med
, vol.208
, pp. 181-193
-
-
Wrammert, J.1
-
25
-
-
77951876927
-
Heterosubtypic neutralizing antibodies are produced by individuals immunized with a seasonal influenza vaccine
-
Corti D et al. 2010 Heterosubtypic neutralizing antibodies are produced by individuals immunized with a seasonal influenza vaccine. J. Clin. Invest. 120, 1663-1673. (doi:10.1172/JCI41902)
-
(2010)
J. Clin. Invest
, vol.120
, pp. 1663-1673
-
-
Corti, D.1
-
26
-
-
84861872090
-
Pandemic H1N1 influenza vaccine induces a recall response in humans that favors broadly cross-reactive memory B cells
-
Li G-M et al. 2012 Pandemic H1N1 influenza vaccine induces a recall response in humans that favors broadly cross-reactive memory B cells. Proc. Natl Acad. Sci. USA 109, 9047-9052. (doi:10.1073/pnas. 1118979109)
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, pp. 9047-9052
-
-
Li, G.-M.1
-
27
-
-
84855466746
-
Antibody-based protection against HIV infection by vectored immunoprophylaxis
-
Balazs AB, Chen J, Hong CM, Rao DS, Yang L, Baltimore D. 2012 Antibody-based protection against HIV infection by vectored immunoprophylaxis. Nature 481, 81-84. (doi:10.1038/nature10660)
-
(2012)
Nature
, vol.481
, pp. 81-84
-
-
Balazs, A.B.1
Chen, J.2
Hong, C.M.3
Rao, D.S.4
Yang, L.5
Baltimore, D.6
-
28
-
-
84907212727
-
Passive transfer of modest titers of potent and broadly neutralizing anti-HIV monoclonal antibodies block SHIV infection in macaques
-
Shingai M et al. 2014 Passive transfer of modest titers of potent and broadly neutralizing anti-HIV monoclonal antibodies block SHIV infection in macaques. J. Exp. Med. 211, 2061-2074. (doi:10. 1084/jem.20132494)
-
(2014)
J. Exp. Med
, vol.211
, pp. 2061-2074
-
-
Shingai, M.1
-
29
-
-
67149120819
-
Heterogeneous neutralizing antibody and antibody-dependent cell cytotoxicity responses in HIV-1 elite controllers
-
Lambotte O et al. 2009 Heterogeneous neutralizing antibody and antibody-dependent cell cytotoxicity responses in HIV-1 elite controllers. AIDS 23, 897-906. (doi:10.1097/QAD.0b013e328329f97d)
-
(2009)
AIDS
, vol.23
, pp. 897-906
-
-
Lambotte, O.1
-
30
-
-
70349873173
-
Cross-reactive antibody responses to the 2009 pandemic H1N1 influenza virus
-
Hancock K et al. 2009 Cross-reactive antibody responses to the 2009 pandemic H1N1 influenza virus. N. Engl. J. Med. 361, 1945-1952. (doi:10. 1056/NEJMoa0906453)
-
(2009)
N. Engl. J. Med
, vol.361
, pp. 1945-1952
-
-
Hancock, K.1
-
31
-
-
79953885168
-
Wide prevalence of heterosubtypic broadly neutralizing human anti-influenza A antibodies
-
Sui J, Sheehan J, Hwang WC, Bankston LA, Burchett SK, Huang C-Y, Liddington RC, Beigel JH, Marasco WA. 2011 Wide prevalence of heterosubtypic broadly neutralizing human anti-influenza A antibodies. Clin. Infect. Dis. 52, 1003-1009. (doi:10.1093/cid/cir121)
-
(2011)
Clin. Infect. Dis
, vol.52
, pp. 1003-1009
-
-
Sui, J.1
Sheehan, J.2
Hwang, W.C.3
Bankston, L.A.4
Burchett, S.K.5
Huang, C.-Y.6
Liddington, R.C.7
Beigel, J.H.8
Marasco, W.A.9
-
32
-
-
84924034216
-
Preexisting human antibodies neutralize recently emerged H7N9 influenza strains
-
Henry Dunand CJ et al. 2015 Preexisting human antibodies neutralize recently emerged H7N9 influenza strains. J. Clin. Invest. 125, 1255-1268. (doi:10.1172/JCI74374)
-
(2015)
J. Clin. Invest
, vol.125
, pp. 1255-1268
-
-
Henry Dunand, C.J.1
-
33
-
-
77956415891
-
Immunity to pre-1950 H1N1 influenza viruses confers cross-protection against the pandemic swine-origin 2009 A (H1N1) influenza virus
-
Skountzou I et al. 2010 Immunity to pre-1950 H1N1 influenza viruses confers cross-protection against the pandemic swine-origin 2009 A (H1N1) influenza virus. J. Immunol. 185, 1642-1649. (doi:10.4049/ jimmunol.1000091)
-
(2010)
J. Immunol
, vol.185
, pp. 1642-1649
-
-
Skountzou, I.1
-
34
-
-
84884238986
-
Immune history shapes specificity of pandemic H1N1 influenza antibody responses
-
Li Y et al. 2013 Immune history shapes specificity of pandemic H1N1 influenza antibody responses. J. Exp. Med. 210, 1493-1500. (doi:10.1084/jem. 20130212)
-
(2013)
J. Exp. Med
, vol.210
, pp. 1493-1500
-
-
Li, Y.1
-
35
-
-
84914695546
-
Potential antigenic explanation for atypical H1N1 infections among middle-aged adults during the 2013-2014 influenza season
-
Linderman SL et al. 2014 Potential antigenic explanation for atypical H1N1 infections among middle-aged adults during the 2013-2014 influenza season. Proc. Natl Acad. Sci. USA 111, 15 798-15 803. (doi:10.1073/pnas.1409171111)
-
(2014)
Proc. Natl Acad. Sci. USA
, vol.111
, pp. 15 798-15 803
-
-
Linderman, S.L.1
-
36
-
-
84864612944
-
Evidence for antigenic seniority in influenza A (H3N2) antibody responses in southern China
-
Lessler J et al. 2012 Evidence for antigenic seniority in influenza A (H3N2) antibody responses in southern China. PLoS Pathog. 8, e1002802. (doi:10. 1371/journal.ppat.1002802)
-
(2012)
PLoS Pathog
, vol.8
-
-
Lessler, J.1
-
37
-
-
84874092680
-
Lineage structure of the human antibody repertoire in response to influenza vaccination
-
171ra19
-
Jiang N et al. 2013 Lineage structure of the human antibody repertoire in response to influenza vaccination. Sci. Transl. Med. 5, 171ra19. (doi:10. 1126/scitranslmed.3004794)
-
(2013)
Sci. Transl. Med
, vol.5
-
-
Jiang, N.1
-
38
-
-
84892778834
-
Effects of aging, cytomegalovirus infection, and EBV infection on human B cell repertoires
-
Wang C et al. 2013 Effects of aging, cytomegalovirus infection, and EBV infection on human B cell repertoires. J. Immunol. 192, 603-611. (doi:10.4049/jimmunol.1301384)
-
(2013)
J. Immunol
, vol.192
, pp. 603-611
-
-
Wang, C.1
-
39
-
-
84055181361
-
Naive antibody genesegment frequencies are heritable and unaltered by chronic lymphocyte ablation
-
Glanville J et al. 2011 Naive antibody genesegment frequencies are heritable and unaltered by chronic lymphocyte ablation. Proc. Natl Acad. Sci. USA 108, 20 066-20 071. (doi:10.1073/pnas. 1107498108)
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 20 066-20 071
-
-
Glanville, J.1
-
40
-
-
84920997236
-
B-cell repertoire responses to varicella-zoster vaccination in human identical twins
-
Wang C et al. 2015 B-cell repertoire responses to varicella-zoster vaccination in human identical twins. Proc. Natl Acad. Sci. USA 112, 500-505. (doi:10.1073/pnas.1415875112)
-
(2015)
Proc. Natl Acad. Sci. USA
, vol.112
, pp. 500-505
-
-
Wang, C.1
-
41
-
-
80053557269
-
Epitope-specific human influenza antibody repertoires diversify by B cell intraclonal sequence divergence and interclonal convergence
-
Krause JC, Tsibane T, Tumpey TM, Huffman CJ, Briney BS, Smith SA, Basler CF, Crowe JE. 2011 Epitope-specific human influenza antibody repertoires diversify by B cell intraclonal sequence divergence and interclonal convergence. J. Immunol. 187, 3704-3711. (doi:10.4049/jimmunol.1101823)
-
(2011)
J. Immunol
, vol.187
, pp. 3704-3711
-
-
Krause, J.C.1
Tsibane, T.2
Tumpey, T.M.3
Huffman, C.J.4
Briney, B.S.5
Smith, S.A.6
Basler, C.F.7
Crowe, J.E.8
-
42
-
-
84879109338
-
Convergent antibody signatures in human dengue
-
Parameswaran P et al. 2013 Convergent antibody signatures in human dengue. Cell Host Microbe 13, 691-700. (doi:10.1016/j.chom.2013.05.008)
-
(2013)
Cell Host Microbe
, vol.13
, pp. 691-700
-
-
Parameswaran, P.1
-
43
-
-
84882589754
-
Multidonor analysis reveals structural elements, genetic determinants, and maturation pathway for HIV-1 neutralization by VRC01-class antibodies
-
Zhou T et al. 2013 Multidonor analysis reveals structural elements, genetic determinants, and maturation pathway for HIV-1 neutralization by VRC01-class antibodies. Immunity 39, 245-258. (doi:10.1016/j.immuni.2013.04.012)
-
(2013)
Immunity
, vol.39
, pp. 245-258
-
-
Zhou, T.1
-
44
-
-
84885979012
-
The shape of the lymphocyte receptor repertoire: Lessons from the B cell receptor
-
Jackson KJL, Kidd MJ, Wang Y, Collins AM. 2013 The shape of the lymphocyte receptor repertoire: lessons from the B cell receptor. Front. Immunol. 4, 263. (doi:10.3389/fimmu.2013.00263)
-
(2013)
Front. Immunol
, vol.4
, pp. 263
-
-
Jackson, K.J.L.1
Kidd, M.J.2
Wang, Y.3
Collins, A.M.4
-
45
-
-
84919667651
-
Identification of antigen-specific B cell receptor sequences using public repertoire analysis
-
Tru¨ck J, Ramasamy MN, Galson JD, Rance R, Parkhill J, Lunter G, Pollard AJ, Kelly DF. 2015 Identification of antigen-specific B cell receptor sequences using public repertoire analysis. J. Immunol. 194, 252-261. (doi:10.4049/ jimmunol.1401405)
-
(2015)
J. Immunol
, vol.194
, pp. 252-261
-
-
Tru¨ck, J.1
Ramasamy, M.N.2
Galson, J.D.3
Rance, R.4
Parkhill, J.5
Lunter, G.6
Pollard, A.J.7
Kelly, D.F.8
-
46
-
-
37049242573
-
Immunological specificity, unique combinations of selected natural globulins provide an alternative to the classical concept
-
Talmage DW. 1959 Immunological specificity, unique combinations of selected natural globulins provide an alternative to the classical concept. Science 129, 1643-1648. (doi:10.1126/science.129. 3364.1643)
-
(1959)
Science
, vol.129
, pp. 1643-1648
-
-
Talmage, D.W.1
-
48
-
-
0011084483
-
Variations in affinities of antibodies during the immune response
-
Eisen HN, Siskind GW. 1964 Variations in affinities of antibodies during the immune response. Biochemistry 3, 996-1008. (doi:10.1021/ bi00895a027)
-
(1964)
Biochemistry
, vol.3
, pp. 996-1008
-
-
Eisen, H.N.1
Siskind, G.W.2
-
49
-
-
0001492287
-
Delineation of the thymic and bursal lymphoid systems in the chicken
-
Cooper MD, Peterson RD, Good RA. 1965 Delineation of the thymic and bursal lymphoid systems in the chicken. Nature 205, 143-146. (doi:10.1038/ 205143a0)
-
(1965)
Nature
, vol.205
, pp. 143-146
-
-
Cooper, M.D.1
Peterson, R.D.2
Good, R.A.3
-
50
-
-
77955483636
-
Optimality of mutation and selection in germinal centers
-
Zhang J, Shakhnovich EI. 2010 Optimality of mutation and selection in germinal centers. PLoS Comput. Biol. 6, e1000800. (doi:10.1371/journal. pcbi.1000800)
-
(2010)
PLoS Comput. Biol
, vol.6
-
-
Zhang, J.1
Shakhnovich, E.I.2
-
51
-
-
84855512128
-
Memory B cells, but not long-lived plasma cells, possess antigen specificities for viral escape mutants
-
Purtha WE, Tedder TF, Johnson S, Bhattacharya D, Diamond MS. 2011 Memory B cells, but not long-lived plasma cells, possess antigen specificities for viral escape mutants. J. Exp. Med. 208, 2599-2606. (doi:10.1084/jem.20110740)
-
(2011)
J. Exp. Med
, vol.208
, pp. 2599-2606
-
-
Purtha, W.E.1
Tedder, T.F.2
Johnson, S.3
Bhattacharya, D.4
Diamond, M.S.5
-
52
-
-
73949116413
-
Precise determination of the diversity of a combinatorial antibody library gives insight into the human immunoglobulin repertoire
-
Glanville J et al. 2009 Precise determination of the diversity of a combinatorial antibody library gives insight into the human immunoglobulin repertoire. Proc. Natl Acad. Sci. USA 106, 20 216-20 221. (doi:10.1073/pnas.0909775106)
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 20 216-20 221
-
-
Glanville, J.1
-
53
-
-
84929191605
-
How a well-adapted immune system is organized
-
Mayer A, Balasubramanian V, Mora T, Walczak AM. 2015 How a well-adapted immune system is organized. Proc. Natl Acad. Sci. USA 112, 5950-5955. (doi:10.1073/pnas.1421827112)
-
(2015)
Proc. Natl Acad. Sci. USA
, vol.112
, pp. 5950-5955
-
-
Mayer, A.1
Balasubramanian, V.2
Mora, T.3
Walczak, A.M.4
-
54
-
-
84922261187
-
B cell Variable genes have evolved their codon usage to focus the targeted patterns of somatic mutation on the complementarity determining regions
-
Saini J, Hershberg U. 2015 B cell Variable genes have evolved their codon usage to focus the targeted patterns of somatic mutation on the complementarity determining regions. Mol. Immunol. 65, 157-167. (doi:10.1016/j.molimm. 2015.01.001)
-
(2015)
Mol. Immunol
, vol.65
, pp. 157-167
-
-
Saini, J.1
Hershberg, U.2
-
55
-
-
84923195015
-
Overlapping hotspots in CDRs are critical sites for V region diversification
-
Wei L, Chahwan R, Wang S, Wang X, Pham PT, Goodman MF, Bergman A, Scharff MD, MacCarthy T. 2015 Overlapping hotspots in CDRs are critical sites for V region diversification. Proc. Natl Acad. Sci. USA 112, E728-E737. (doi:10.1073/pnas.1500788112)
-
(2015)
Proc. Natl Acad. Sci. USA
, vol.112
, pp. E728-E737
-
-
Wei, L.1
Chahwan, R.2
Wang, S.3
Wang, X.4
Pham, P.T.5
Goodman, M.F.6
Bergman, A.7
Scharff, M.D.8
MacCarthy, T.9
-
56
-
-
0041689676
-
Predominant autoantibody production by early human B cell precursors
-
Wardemann H, Yurasov S, Schaefer A, Young JW, Meffre E, Nussenzweig MC. 2003 Predominant autoantibody production by early human B cell precursors. Science 301, 1374-1377. (doi:10.1126/ science.1086907)
-
(2003)
Science
, vol.301
, pp. 1374-1377
-
-
Wardemann, H.1
Yurasov, S.2
Schaefer, A.3
Young, J.W.4
Meffre, E.5
Nussenzweig, M.C.6
-
57
-
-
84874223925
-
Molecular deconvolution of the monoclonal antibodies that comprise the polyclonal serum response
-
Wine Y et al. 2013 Molecular deconvolution of the monoclonal antibodies that comprise the polyclonal serum response. Proc. Natl Acad. Sci. USA 110, 2993-2998. (doi:10.1073/pnas.1213737110)
-
(2013)
Proc. Natl Acad. Sci. USA
, vol.110
, pp. 2993-2998
-
-
Wine, Y.1
-
58
-
-
84893831480
-
The promise and challenge of high-throughput sequencing of the antibody repertoire
-
Georgiou G, Ippolito GC, Beausang J, Busse CE, Wardemann H, Quake SR. 2014 The promise and challenge of high-throughput sequencing of the antibody repertoire. Nat. Biotechnol. 32, 158-168. (doi:10.1038/nbt.2782)
-
(2014)
Nat. Biotechnol
, vol.32
, pp. 158-168
-
-
Georgiou, G.1
Ippolito, G.C.2
Beausang, J.3
Busse, C.E.4
Wardemann, H.5
Quake, S.R.6
-
59
-
-
84925284996
-
In-depth determination and analysis of the human paired heavy- and light-chain antibody repertoire
-
DeKosky BJ, Kojima T, Rodin A, Charab W, Ippolito GC, Ellington AD, Georgiou G. 2015 In-depth determination and analysis of the human paired heavy- and light-chain antibody repertoire. Nat. Med. 21, 86-91. (doi:10.1038/nm.3743)
-
(2015)
Nat. Med
, vol.21
, pp. 86-91
-
-
DeKosky, B.J.1
Kojima, T.2
Rodin, A.3
Charab, W.4
Ippolito, G.C.5
Ellington, A.D.6
Georgiou, G.7
-
60
-
-
44449118948
-
Rapid cloning of highaffinity human monoclonal antibodies against influenza virus
-
Wrammert J et al. 2008 Rapid cloning of highaffinity human monoclonal antibodies against influenza virus. Nature 453, 667-671. (doi:10. 1038/nature06890)
-
(2008)
Nature
, vol.453
, pp. 667-671
-
-
Wrammert, J.1
-
61
-
-
78149477766
-
Germinal center dynamics revealed by multiphoton microscopy with a photoactivatable fluorescent reporter
-
Victora GD, Schwickert TA, Fooksman DR, Kamphorst AO, Meyer-Hermann M, Dustin ML, Nussenzweig MC. 2010 Germinal center dynamics revealed by multiphoton microscopy with a photoactivatable fluorescent reporter. Cell 143, 592-605. (doi:10. 1016/j.cell.2010.10.032)
-
(2010)
Cell
, vol.143
, pp. 592-605
-
-
Victora, G.D.1
Schwickert, T.A.2
Fooksman, D.R.3
Kamphorst, A.O.4
Meyer-Hermann, M.5
Dustin, M.L.6
Nussenzweig, M.C.7
-
62
-
-
34548496893
-
Fc receptor but not complement binding is important in antibody protection against HIV
-
Hessell AJ et al. 2007 Fc receptor but not complement binding is important in antibody protection against HIV. Nature 449, 101-104. (doi:10.1038/nature06106)
-
(2007)
Nature
, vol.449
, pp. 101-104
-
-
Hessell, A.J.1
-
63
-
-
84908077691
-
Broadly neutralizing anti-HIV-1 antibodies require Fc effector functions for in vivo activity
-
Bournazos S, Klein F, Pietzsch J, Seaman MS, Nussenzweig MC, Ravetch JV. 2014 Broadly neutralizing anti-HIV-1 antibodies require Fc effector functions for in vivo activity. Cell 158, 1243-1253. (doi:10.1016/j.cell.2014.08.023)
-
(2014)
Cell
, vol.158
, pp. 1243-1253
-
-
Bournazos, S.1
Klein, F.2
Pietzsch, J.3
Seaman, M.S.4
Nussenzweig, M.C.5
Ravetch, J.V.6
-
64
-
-
0020534965
-
Somatic generation of antibody diversity
-
Tonegawa S. 1983 Somatic generation of antibody diversity. Nature 302, 575-581. (doi:10.1038/ 302575a0)
-
(1983)
Nature
, vol.302
, pp. 575-581
-
-
Tonegawa, S.1
-
65
-
-
79961160227
-
High-resolution description of antibody heavychain repertoires in humans
-
Arnaout R, Lee W, Cahill P, Honan T, Sparrow T, Weiand M, Nusbaum C, Rajewsky K, Koralov SB. 2011 High-resolution description of antibody heavychain repertoires in humans. PLoS ONE 6, e22365. (doi:10.1371/journal.pone.0022365)
-
(2011)
PLoS ONE
, vol.6
-
-
Arnaout, R.1
Lee, W.2
Cahill, P.3
Honan, T.4
Sparrow, T.5
Weiand, M.6
Nusbaum, C.7
Rajewsky, K.8
Koralov, S.B.9
-
66
-
-
0023652303
-
Somatic diversification of the chicken immunoglobulin light chain gene is limited to the rearranged variable gene segment
-
Thompson CB, Neiman PE. 1987 Somatic diversification of the chicken immunoglobulin light chain gene is limited to the rearranged variable gene segment. Cell 48, 369-378. (doi:10.1016/ 0092-8674(87)90188-7)
-
(1987)
Cell
, vol.48
, pp. 369-378
-
-
Thompson, C.B.1
Neiman, P.E.2
-
67
-
-
0025676044
-
Somatic diversification of immunoglobulin heavy chain VDJ genes: Evidence for somatic gene conversion in rabbits
-
Becker RS, Knight KL. 1990 Somatic diversification of immunoglobulin heavy chain VDJ genes: evidence for somatic gene conversion in rabbits. Cell 63, 987-997. (doi:10.1016/0092-8674(90)90502-6)
-
(1990)
Cell
, vol.63
, pp. 987-997
-
-
Becker, R.S.1
Knight, K.L.2
-
68
-
-
0013803936
-
Antigens in immunity: VII. Analysis of immunological memory
-
Nossal G, Austin CM, Ada GL. 1965 Antigens in immunity: VII. Analysis of immunological memory. Immunology 9, 333.
-
(1965)
Immunology
, vol.9
, pp. 333
-
-
Nossal, G.1
Austin, C.M.2
Ada, G.L.3
-
69
-
-
0014943022
-
Variability in the lambda light chain sequences of mouse antibody
-
Weigert MG, Cesari IM, Yonkovich SJ, Cohn M. 1970 Variability in the lambda light chain sequences of mouse antibody. Nature 228, 1045-1047. (doi:10. 1038/2281045a0)
-
(1970)
Nature
, vol.228
, pp. 1045-1047
-
-
Weigert, M.G.1
Cesari, I.M.2
Yonkovich, S.J.3
Cohn, M.4
-
70
-
-
0008476550
-
Generation of antibody diversity in the immune response of BALB/c mice to influenza virus hemagglutinin
-
McKean D, Huppi K, Bell M, Staudt L, Gerhard W, Weigert M. 1984 Generation of antibody diversity in the immune response of BALB/c mice to influenza virus hemagglutinin. Proc. Natl Acad. Sci. USA 81, 3180-3184. (doi:10.1073/pnas.81.10.3180)
-
(1984)
Proc. Natl Acad. Sci. USA
, vol.81
, pp. 3180-3184
-
-
McKean, D.1
Huppi, K.2
Bell, M.3
Staudt, L.4
Gerhard, W.5
Weigert, M.6
-
71
-
-
84907681865
-
Immunoglobulin gene insertions and deletions in the affinity maturation of HIV-1 broadly reactive neutralizing antibodies
-
Kepler TB et al. 2014 Immunoglobulin gene insertions and deletions in the affinity maturation of HIV-1 broadly reactive neutralizing antibodies. Cell Host Microbe 16, 304-313. (doi:10.1016/j.chom. 2014.08.006)
-
(2014)
Cell Host Microbe
, vol.16
, pp. 304-313
-
-
Kepler, T.B.1
-
72
-
-
0034268780
-
Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme
-
Muramatsu M, Kinoshita K, Fagarasan S, Yamada S, Shinkai Y, Honjo T. 2000 Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme. Cell 102, 553-563. (doi:10.1016/S0092- 8674(00)00078-7)
-
(2000)
Cell
, vol.102
, pp. 553-563
-
-
Muramatsu, M.1
Kinoshita, K.2
Fagarasan, S.3
Yamada, S.4
Shinkai, Y.5
Honjo, T.6
-
73
-
-
0034264851
-
Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the hyper-IgM syndrome (HIGM2)
-
Revy P et al. 2000 Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the hyper-IgM syndrome (HIGM2). Cell 102, 565-575. (doi:10.1016/S0092-8674(00) 00079-9)
-
(2000)
Cell
, vol.102
, pp. 565-575
-
-
Revy, P.1
-
74
-
-
0036863733
-
RNA editing enzyme APOBEC1 and some of its homologs can act as DNA mutators
-
Harris RS, Petersen-Mahrt SK, Neuberger MS. 2002 RNA editing enzyme APOBEC1 and some of its homologs can act as DNA mutators. Mol Cell 10, 1247-1253. (doi:10.1016/S1097-2765(02) 00742-6)
-
(2002)
Mol Cell
, vol.10
, pp. 1247-1253
-
-
Harris, R.S.1
Petersen-Mahrt, S.K.2
Neuberger, M.S.3
-
75
-
-
0035379581
-
Somatic mutation hotspots correlate with DNA polymerase h error spectrum
-
Rogozin IB, Pavlov YI, Bebenek K, Matsuda T, Kunkel TA. 2001 Somatic mutation hotspots correlate with DNA polymerase h error spectrum. Nat. Immunol. 2, 530-536. (doi:10.1038/88732)
-
(2001)
Nat. Immunol
, vol.2
, pp. 530-536
-
-
Rogozin, I.B.1
Pavlov, Y.I.2
Bebenek, K.3
Matsuda, T.4
Kunkel, T.A.5
-
76
-
-
18644366944
-
Intricate targeting of immunoglobulin somatic hypermutation maximizes the efficiency of affinity maturation
-
Zheng N-Y, Wilson K, Jared M, Wilson PC. 2005 Intricate targeting of immunoglobulin somatic hypermutation maximizes the efficiency of affinity maturation. J. Exp. Med. 201, 1467-1478. (doi:10. 1084/jem.20042483)
-
(2005)
J. Exp. Med
, vol.201
, pp. 1467-1478
-
-
Zheng, N.-Y.1
Wilson, K.2
Jared, M.3
Wilson, P.C.4
-
77
-
-
0027499308
-
Passenger transgenes reveal intrinsic specificity of the antibody hypermutation mechanism: Clustering, polarity, and specific hot spots
-
Betz AG, Rada C, Pannell R, Milstein C, Neuberger MS. 1993 Passenger transgenes reveal intrinsic specificity of the antibody hypermutation mechanism: clustering, polarity, and specific hot spots. Proc. Natl Acad. Sci. USA 90, 2385-2388. (doi:10.1073/pnas.90.6.2385)
-
(1993)
Proc. Natl Acad. Sci. USA
, vol.90
, pp. 2385-2388
-
-
Betz, A.G.1
Rada, C.2
Pannell, R.3
Milstein, C.4
Neuberger, M.S.5
-
78
-
-
84937675261
-
The analysis of clonal expansions in normal and autoimmune B cell repertoires
-
Hershberg U, Luning Prak ET. 2015 The analysis of clonal expansions in normal and autoimmune B cell repertoires. Phil. Trans. R. Soc. B 370, 20140239. (doi:10.1098/rstb.2014.0239)
-
(2015)
Phil. Trans. R. Soc. B
, vol.370
-
-
Hershberg, U.1
Luning Prak, E.T.2
-
79
-
-
83755184217
-
Is there a typical germinal center? A large-scale immunohistological study on the cellular composition of germinal centers during the hapten-carrier-driven primary immune response in mice
-
Wittenbrink N, Klein A, Weiser AA, Schuchhardt J, Or-Guil M. 2011 Is there a typical germinal center? A large-scale immunohistological study on the cellular composition of germinal centers during the hapten-carrier-driven primary immune response in mice. J. Immunol. 187, 6185-6196. (doi:10.4049/ jimmunol.1101440)
-
(2011)
J. Immunol
, vol.187
, pp. 6185-6196
-
-
Wittenbrink, N.1
Klein, A.2
Weiser, A.A.3
Schuchhardt, J.4
Or-Guil, M.5
-
80
-
-
0021855144
-
Inter- and intraclonal diversity in the antibody response to influenza hemagglutinin
-
Clarke SH, Huppi K, Ruezinsky D, Staudt L, Gerhard W, Weigert M. 1985 Inter- and intraclonal diversity in the antibody response to influenza hemagglutinin. J. Exp. Med. 161, 687-704. (doi:10. 1084/jem.161.4.687)
-
(1985)
J. Exp. Med
, vol.161
, pp. 687-704
-
-
Clarke, S.H.1
Huppi, K.2
Ruezinsky, D.3
Staudt, L.4
Gerhard, W.5
Weigert, M.6
-
82
-
-
84877614313
-
Germinal center B cells govern their own fate via antibody feedback
-
Zhang Y et al. 2013 Germinal center B cells govern their own fate via antibody feedback. J. Exp. Med. 210, 457-464. (doi:10.1084/jem.20120150)
-
(2013)
J. Exp. Med
, vol.210
, pp. 457-464
-
-
Zhang, Y.1
-
83
-
-
84882432416
-
Genetic measurement of memory B-cell recall using antibody repertoire sequencing
-
Vollmers C, Sit RV, Weinstein JA, Dekker CL, Quake SR. 2013 Genetic measurement of memory B-cell recall using antibody repertoire sequencing. Proc. Natl Acad. Sci. USA 110, 13 463-13 468. (doi:10. 1073/pnas.1312146110)
-
(2013)
Proc. Natl Acad. Sci. USA
, vol.110
, pp. 13 463-13 468
-
-
Vollmers, C.1
Sit, R.V.2
Weinstein, J.A.3
Dekker, C.L.4
Quake, S.R.5
-
84
-
-
0031041305
-
Viral superantigen drives extrafollicular and follicular B cell differentiation leading to virus-specific antibody production
-
Luther SA, Gulbranson-Judge A, Acha-Orbea H, MacLennan IC. 1997 Viral superantigen drives extrafollicular and follicular B cell differentiation leading to virus-specific antibody production. J. Exp. Med. 185, 551-562. (doi:10.1084/jem.185.3.551)
-
(1997)
J. Exp. Med
, vol.185
, pp. 551-562
-
-
Luther, S.A.1
Gulbranson-Judge, A.2
Acha-Orbea, H.3
MacLennan, I.C.4
-
85
-
-
77953632929
-
Individual variation in the germline Ig gene repertoire inferred from variable region gene rearrangements
-
Boyd SD et al. 2010 Individual variation in the germline Ig gene repertoire inferred from variable region gene rearrangements. J. Immunol. 184, 6986-6992. (doi:10.4049/jimmunol.1000445)
-
(2010)
J. Immunol
, vol.184
, pp. 6986-6992
-
-
Boyd, S.D.1
-
86
-
-
84937702280
-
The mouse antibody heavy chain repertoire is germline-focused and highly variable between inbred strains
-
Collins AM, Wang Y, Roskin KM, Marquis CP, Jackson KJL. 2015 The mouse antibody heavy chain repertoire is germline-focused and highly variable between inbred strains. Phil. Trans. R. Soc. B 370, 20140236. (doi:10.1098/rstb.2014.0236)
-
(2015)
Phil. Trans. R. Soc. B
, vol.370
-
-
Collins, A.M.1
Wang, Y.2
Roskin, K.M.3
Marquis, C.P.4
Jackson, K.J.L.5
-
87
-
-
0032482172
-
Sequence of the spacer in the recombination signal sequence affects V(D)J rearrangement frequency and correlates with nonrandom Vk usage in vivo
-
Nadel B, Tang A, Escuro G, Lugo G, Feeney AJ. 1998 Sequence of the spacer in the recombination signal sequence affects V(D)J rearrangement frequency and correlates with nonrandom Vk usage in vivo. J. Exp. Med. 187, 1495-1503. (doi:10.1084/jem. 187.9.1495)
-
(1998)
J. Exp. Med
, vol.187
, pp. 1495-1503
-
-
Nadel, B.1
Tang, A.2
Escuro, G.3
Lugo, G.4
Feeney, A.J.5
-
88
-
-
0033918155
-
B-cell repertoire formation: Role of the recombination signal sequence in non-random V segment utilization
-
Feeney AJ, Tang A, Ogwaro KM. 2000 B-cell repertoire formation: role of the recombination signal sequence in non-random V segment utilization. Immunol. Rev. 175, 59-69. (doi:10. 1111/j.1600-065X.2000.imr017508.x)
-
(2000)
Immunol. Rev
, vol.175
, pp. 59-69
-
-
Feeney, A.J.1
Tang, A.2
Ogwaro, K.M.3
-
89
-
-
84875948859
-
Complete haplotype sequence of the human immunoglobulin heavy-chain variable, diversity, and joining genes and characterization of allelic and copy-number variation
-
Watson CT et al. 2013 Complete haplotype sequence of the human immunoglobulin heavy-chain variable, diversity, and joining genes and characterization of allelic and copy-number variation. Am. J. Hum. Genet. 92, 530-546. (doi:10. 1016/j.ajhg.2013.03.004)
-
(2013)
Am. J. Hum. Genet
, vol.92
, pp. 530-546
-
-
Watson, C.T.1
-
90
-
-
84921612155
-
Sequencing of the human IG light chain loci from a hydatidiform mole BAC library reveals locus-specific signatures of genetic diversity
-
Watson CT et al. 2014 Sequencing of the human IG light chain loci from a hydatidiform mole BAC library reveals locus-specific signatures of genetic diversity. Genes Immun. 16, 24-34. (doi:10.1038/ gene.2014.56)
-
(2014)
Genes Immun
, vol.16
, pp. 24-34
-
-
Watson, C.T.1
-
91
-
-
0029664291
-
Expression of the immunoglobulin VH gene 51p1 is proportional to its germline gene copy number
-
Sasso EH, Johnson T, Kipps TJ. 1996 Expression of the immunoglobulin VH gene 51p1 is proportional to its germline gene copy number. J. Clin. Invest. 97, 2074-2080. (doi:10.1172/JCI118644)
-
(1996)
J. Clin. Invest
, vol.97
, pp. 2074-2080
-
-
Sasso, E.H.1
Johnson, T.2
Kipps, T.J.3
-
92
-
-
43349084775
-
Large-scale analysis of human heavy chain V(D)J recombination patterns
-
Volpe JM, Kepler TB. 2008 Large-scale analysis of human heavy chain V(D)J recombination patterns. Immunome Res. 4, 3. (doi:10.1186/1745-7580-4-3)
-
(2008)
Immunome Res
, vol.4
, pp. 3
-
-
Volpe, J.M.1
Kepler, T.B.2
-
93
-
-
77954601328
-
Measurement and clinical monitoring of human lymphocyte clonality by massively parallel V-D-J pyrosequencing
-
t 12ra23
-
Boyd SD et al. 2009 Measurement and clinical monitoring of human lymphocyte clonality by massively parallel V-D-J pyrosequencing. Sci. Transl. Med. 1, 12ra23. (doi:10.1126/scitranslmed.3000540)
-
(2009)
Sci. Transl. Med
, vol.1
-
-
Boyd, S.D.1
-
94
-
-
84866495323
-
Human antibodies that neutralize HIV-1: Identification, structures, and B cell ontogenies
-
Kwong PD, Mascola JR. 2012 Human antibodies that neutralize HIV-1: identification, structures, and B cell ontogenies. Immunity 37, 412-425. (doi:10. 1016/j.immuni.2012.08.012)
-
(2012)
Immunity
, vol.37
, pp. 412-425
-
-
Kwong, P.D.1
Mascola, J.R.2
-
95
-
-
84876797103
-
Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus
-
Liao H-X et al. 2013 Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus. Nature 496, 469-476. (doi:10.1038/nature12053)
-
(2013)
Nature
, vol.496
, pp. 469-476
-
-
Liao, H.-X.1
-
96
-
-
84904263671
-
Human responses to influenza vaccination show seroconversion signatures and convergent antibody rearrangements
-
Jackson KJL et al. 2014 Human responses to influenza vaccination show seroconversion signatures and convergent antibody rearrangements. Cell Host Microbe 16, 105-114 (doi:10.1016/j.chom.2014.05.013)
-
(2014)
Cell Host Microbe
, vol.16
, pp. 105-114
-
-
Jackson, K.J.L.1
-
97
-
-
84937696301
-
Restricted, canonical, stereotyped and convergent immunoglobulin responses
-
Dunand CJH, Wilson PC. 2015 Restricted, canonical, stereotyped and convergent immunoglobulin responses. Phil. Trans. R. Soc. B 370, 20140238. (doi:10.1098/rstb.2014.0238)
-
(2015)
Phil. Trans. R. Soc. B
, vol.370
-
-
Dunand, C.J.H.1
Wilson, P.C.2
-
99
-
-
84867834056
-
IMGT/HighV-QUEST: The IMGTw web portal for immunoglobulin (IG) or antibody and T cell receptor (TR) analysis from NGS high throughput and deep sequencing
-
Alamyar E, Giudicelli V, Li S, Duroux P, Lefranc M-P. 2012 IMGT/HighV-QUEST: the IMGTw web portal for immunoglobulin (IG) or antibody and T cell receptor (TR) analysis from NGS high throughput and deep sequencing. Immunome Res. 8, 26.
-
(2012)
Immunome Res
, vol.8
, pp. 26
-
-
Alamyar, E.1
Giudicelli, V.2
Li, S.3
Duroux, P.4
Lefranc, M.-P.5
-
100
-
-
84883563447
-
IgBLAST: An immunoglobulin variable domain sequence analysis tool
-
Ye J, Ma N, Madden TL, Ostell JM. 2013 IgBLAST: an immunoglobulin variable domain sequence analysis tool. Nucleic Acids Res. 41, W34-W40. (doi:10. 1093/nar/gkt382)
-
(2013)
Nucleic Acids Res
, vol.41
, pp. W34-W40
-
-
Ye, J.1
Ma, N.2
Madden, T.L.3
Ostell, J.M.4
-
101
-
-
34547840205
-
iHMMune-align: Hidden Markov model-based alignment and identification of germline genes in rearranged immunoglobulin gene sequences
-
Gae¨ta BA, Malming HR, Jackson KJL, Bain ME, Wilson P, Collins AM. 2007 iHMMune-align: hidden Markov model-based alignment and identification of germline genes in rearranged immunoglobulin gene sequences. Bioinformatics 23, 1580-1587. (doi:10.1093/bioinformatics/btm147)
-
(2007)
Bioinformatics
, vol.23
, pp. 1580-1587
-
-
Gae¨ta, B.A.1
Malming, H.R.2
Jackson, K.J.L.3
Bain, M.E.4
Wilson, P.5
Collins, A.M.6
-
102
-
-
77951949737
-
SoDA2: A hidden Markov model approach for identification of immunoglobulin rearrangements
-
Munshaw S, Kepler TB. 2010 SoDA2: a hidden Markov model approach for identification of immunoglobulin rearrangements. Bioinformatics 26, 867-872. (doi:10.1093/bioinformatics/btq056)
-
(2010)
Bioinformatics
, vol.26
, pp. 867-872
-
-
Munshaw, S.1
Kepler, T.B.2
-
103
-
-
84937682989
-
Assigning and visualizing germline genes in antibody repertoires
-
Frost SDW, Murrell B, Hossain ASMM, Silverman GJ, Pond SLK. 2015 Assigning and visualizing germline genes in antibody repertoires. Phil. Trans. R. Soc. B 370, 20140240. (doi:10.1098/rstb. 2014.0240)
-
(2015)
Phil. Trans. R. Soc. B
, vol.370
-
-
Frost, S.D.W.1
Murrell, B.2
Hossain, A.S.M.M.3
Silverman, G.J.4
Pond, S.L.K.5
-
104
-
-
84937719428
-
Inferring processes underlying B-cell repertoire diversity
-
Elhanati Y, Sethna Z, Marcou Q, Callan Jr CG, Mora T, Walczak AM. 2015 Inferring processes underlying B-cell repertoire diversity. Phil. Trans. R. Soc. B 370, 20140243. (doi:10.1098/rstb.2014.0243)
-
(2015)
Phil. Trans. R. Soc. B
, vol.370
-
-
Elhanati, Y.1
Sethna, Z.2
Marcou, Q.3
Callan Jr, C.G.4
Mora, T.5
Walczak, A.M.6
-
105
-
-
85000360533
-
Reconstructing a B-cell clonal lineage. I. Statistical inference of unobserved ancestors
-
Kepler TB. 2013 Reconstructing a B-cell clonal lineage. I. Statistical inference of unobserved ancestors. F1000Res 2, 103. (doi:10.12688/ f1000research.2-103.v1)
-
(2013)
F1000Res
, vol.2
, pp. 103
-
-
Kepler, T.B.1
-
106
-
-
84923657453
-
Automated analysis of high-throughput B-cell sequencing data reveals a high frequency of novel immunoglobulin V gene segment alleles
-
Gadala-Maria D, Yaari G, Uduman M, Kleinstein SH. 2015 Automated analysis of high-throughput B-cell sequencing data reveals a high frequency of novel immunoglobulin V gene segment alleles. Proc. Natl Acad. Sci. USA 112, E862-E870. (doi:10.1073/pnas. 1417683112)
-
(2015)
Proc. Natl Acad. Sci. USA
, vol.112
, pp. E862-E870
-
-
Gadala-Maria, D.1
Yaari, G.2
Uduman, M.3
Kleinstein, S.H.4
-
107
-
-
79955109675
-
Determinism and stochasticity during maturation of the zebrafish antibody repertoire
-
Jiang N, Weinstein JA, Penland L, White 3rd RA, Fisher DS, Quake SR. 2011 Determinism and stochasticity during maturation of the zebrafish antibody repertoire. Proc. Natl Acad. Sci. USA 108, 5348-5353. (doi:10.1073/pnas.1014277108)
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 5348-5353
-
-
Jiang, N.1
Weinstein, J.A.2
Penland, L.3
White, R.A.4
Fisher, D.S.5
Quake, S.R.6
-
108
-
-
84887433048
-
Network properties derived from deep sequencing of human B-cell receptor repertoires delineate B-cell populations
-
Bashford-Rogers RJM, Palser AL, Huntly BJ, Rance R, Vassiliou GS, Follows GA, Kellam P. 2013 Network properties derived from deep sequencing of human B-cell receptor repertoires delineate B-cell populations. Genome Res. 23, 1874-1884. (doi:10. 1101/gr.154815.113)
-
(2013)
Genome Res
, vol.23
, pp. 1874-1884
-
-
Bashford-Rogers, R.J.M.1
Palser, A.L.2
Huntly, B.J.3
Rance, R.4
Vassiliou, G.S.5
Follows, G.A.6
Kellam, P.7
-
109
-
-
84899991983
-
Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies
-
Doria-Rose NA et al. 2014 Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies. Nature 509, 55-62. (doi:10.1038/nature13036)
-
(2014)
Nature
, vol.509
, pp. 55-62
-
-
Doria-Rose, N.A.1
-
110
-
-
84937698863
-
Quantifying evolutionary constraints on B-cell affinity maturation
-
McCoy CO, Bedford T, Minin VN, Bradley P, Robins H, Matsen IV FA. 2015 Quantifying evolutionary constraints on B-cell affinity maturation. Phil. Trans. R. Soc. B 370, 20140244. (doi:10.1098/rstb. 2014.0244)
-
(2015)
Phil. Trans. R. Soc. B
, vol.370
-
-
McCoy, C.O.1
Bedford, T.2
Minin, V.N.3
Bradley, P.4
Robins, H.5
Matsen IV, F.A.6
-
111
-
-
84937681813
-
The mutation patterns in B-cell immunoglobulin receptors reflect the influence of selection acting at multiple time-scales
-
Yaari G, Benichou JIC, Vander Heiden JA, Kleinstein SH, Louzoun Y. 2015 The mutation patterns in B-cell immunoglobulin receptors reflect the influence of selection acting at multiple time-scales. Phil. Trans. R. Soc. B 370, 20140242. (doi:10.1098/rstb. 2014.0242)
-
(2015)
Phil. Trans. R. Soc. B
, vol.370
-
-
Yaari, G.1
Benichou, J.I.C.2
Vander Heiden, J.A.3
Kleinstein, S.H.4
Louzoun, Y.5
-
112
-
-
84895858301
-
A predictive fitness model for influenza
-
Łuksza M, La¨ssig M. 2014 A predictive fitness model for influenza. Nature 507, 57-61. (doi:10.1038/ nature13087)
-
(2014)
Nature
, vol.507
, pp. 57-61
-
-
Łuksza, M.1
La¨ssig, M.2
-
113
-
-
84898728051
-
Integrating influenza antigenic dynamics with molecular evolution
-
Bedford T et al. 2014 Integrating influenza antigenic dynamics with molecular evolution. Elife 3, e01914. (doi:10.7554/eLife.01914)
-
(2014)
Elife
, vol.3
-
-
Bedford, T.1
-
114
-
-
84906255301
-
Efficient Bayesian inference under the structured coalescent
-
Vaughan TG, Ku¨hnert D, Popinga A, Welch D, Drummond AJ. 2014 Efficient Bayesian inference under the structured coalescent. Bioinformatics 30, 2272-2279. (doi:10.1093/bioinformatics/btu201)
-
(2014)
Bioinformatics
, vol.30
, pp. 2272-2279
-
-
Vaughan, T.G.1
Ku¨hnert, D.2
Popinga, A.3
Welch, D.4
Drummond, A.J.5
-
116
-
-
0021254368
-
Immunodominant protein epitopes I. Induction of suppression to hen egg white lysozyme is obliterated by removal of the first three N-terminal amino acids
-
Wicker LS, Katz M, Sercarz EE, Miller A. 1984 Immunodominant protein epitopes I. Induction of suppression to hen egg white lysozyme is obliterated by removal of the first three N-terminal amino acids. Eur. J. Immunol. 14, 442-447. (doi:10.1002/eji.1830140511)
-
(1984)
Eur. J. Immunol
, vol.14
, pp. 442-447
-
-
Wicker, L.S.1
Katz, M.2
Sercarz, E.E.3
Miller, A.4
-
117
-
-
0027200302
-
Redistribution of a murine humoral immune response following removal of an immunodominant B cell epitope from a recombinant fusion protein
-
Scheerlinck JP, DeLeys R, Saman E, Brys L, Geldhof A, De Baetselier P. 1993 Redistribution of a murine humoral immune response following removal of an immunodominant B cell epitope from a recombinant fusion protein. Mol. Immunol. 30, 733-739. (doi:10.1016/0161-5890(93)90144-Z)
-
(1993)
Mol. Immunol
, vol.30
, pp. 733-739
-
-
Scheerlinck, J.P.1
DeLeys, R.2
Saman, E.3
Brys, L.4
Geldhof, A.5
De Baetselier, P.6
-
118
-
-
0028107775
-
Antigen-specific early primary humoral responses modulate immunodominance of B cell epitopes
-
Vijayakrishnan L, Kumar V, Agrewala JN, Mishra GC, Rao KV. 1994 Antigen-specific early primary humoral responses modulate immunodominance of B cell epitopes. J. Immunol. 153, 1613-1625.
-
(1994)
J. Immunol
, vol.153
, pp. 1613-1625
-
-
Vijayakrishnan, L.1
Kumar, V.2
Agrewala, J.N.3
Mishra, G.C.4
Rao, K.V.5
-
119
-
-
84937717442
-
Trade-offs in antibody repertoires to complex antigens
-
Childs LM, Baskerville EB, Cobey S. 2015 Trade-offs in antibody repertoires to complex antigens. Phil. Trans. R. Soc. B 370, 20140245. (doi:10.1098/rstb. 2014.0245)
-
(2015)
Phil. Trans. R. Soc. B
, vol.370
-
-
Childs, L.M.1
Baskerville, E.B.2
Cobey, S.3
-
120
-
-
84911940230
-
Staphylococcus aureus infection induces protein A-mediated immune evasion in humans
-
Pauli NT et al. 2014 Staphylococcus aureus infection induces protein A-mediated immune evasion in humans. J. Exp. Med. 211, 2331-2339. (doi:10. 1084/jem.20141404)
-
(2014)
J. Exp. Med
, vol.211
, pp. 2331-2339
-
-
Pauli, N.T.1
-
121
-
-
84924060844
-
Advances in the development of influenza virus vaccines
-
Krammer F, Palese P. 2015 Advances in the development of influenza virus vaccines. Nat. Rev. Drug Discov. 14, 167-182. (doi:10.1038/nrd4529)
-
(2015)
Nat. Rev. Drug Discov
, vol.14
, pp. 167-182
-
-
Krammer, F.1
Palese, P.2
-
122
-
-
66649100756
-
Differential neutralization efficiency of hemagglutinin epitopes, antibody interference, and the design of influenza vaccines
-
Ndifon W, Wingreen NS, Levin SA. 2009 Differential neutralization efficiency of hemagglutinin epitopes, antibody interference, and the design of influenza vaccines. Proc. Natl Acad. Sci. USA 106, 8701-8706. (doi:10.1073/pnas.0903427106)
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 8701-8706
-
-
Ndifon, W.1
Wingreen, N.S.2
Levin, S.A.3
-
123
-
-
0006348842
-
On the doctrine of original antigenic sin
-
Francis Jr T. 1960 On the doctrine of original antigenic sin. Proc. Am. Philos. Soc. 104, 572-578.
-
(1960)
Proc. Am. Philos. Soc
, vol.104
, pp. 572-578
-
-
Francis Jr, T.1
-
124
-
-
70349237173
-
Original antigenic sin responses to influenza viruses
-
Kim JH, Skountzou I, Compans R, Jacob J. 2009 Original antigenic sin responses to influenza viruses. J. Immunol. 183, 3294-3301. (doi:10.4049/ jimmunol.0900398)
-
(2009)
J. Immunol
, vol.183
, pp. 3294-3301
-
-
Kim, J.H.1
Skountzou, I.2
Compans, R.3
Jacob, J.4
-
125
-
-
84930083052
-
Viral receptor-binding site antibodies with diverse germline origins
-
Schmidt AG et al. 2015 Viral receptor-binding site antibodies with diverse germline origins. Cell 161, 1026-1034. (doi:10.1016/j.cell.2015. 04.028)
-
(2015)
Cell
, vol.161
, pp. 1026-1034
-
-
Schmidt, A.G.1
-
126
-
-
84937696312
-
Masking of antigenic epitopes by antibodies shapes the humoral immune response to influenza
-
Zarnitsyna VI, Ellebedy AH, Davis C, Jacob J, Ahmed R, Antia R. 2015 Masking of antigenic epitopes by antibodies shapes the humoral immune response to influenza. Phil. Trans. R. Soc. B 370, 20140248. (doi:10.1098/rstb.2014.0248)
-
(2015)
Phil. Trans. R. Soc. B
, vol.370
-
-
Zarnitsyna, V.I.1
Ellebedy, A.H.2
Davis, C.3
Jacob, J.4
Ahmed, R.5
Antia, R.6
-
127
-
-
84937709395
-
The challenges of modelling antibody repertoire dynamics in HIV infection
-
Luo S, Perelson AS. 2015 The challenges of modelling antibody repertoire dynamics in HIV infection. Phil. Trans. R. Soc. B 370, 20140247. (doi:10.1098/rstb.2014.0247)
-
(2015)
Phil. Trans. R. Soc. B
, vol.370
-
-
Luo, S.1
Perelson, A.S.2
-
128
-
-
85000814907
-
Dynamics of immunoglobulin sequence diversity in HIV-1 infected individuals
-
Hoehn KB et al. 2015 Dynamics of immunoglobulin sequence diversity in HIV-1 infected individuals. Phil. Trans. R. Soc. B 370, 20140241. (doi:10.1098/ rstb.2014.0241)
-
(2015)
Phil. Trans. R. Soc. B
, vol.370
-
-
Hoehn, K.B.1
-
129
-
-
84911909440
-
Next-generation sequencing and protein mass spectrometry for the comprehensive analysis of human cellular and serum antibody repertoires
-
Lavinder JJ, Horton AP, Georgiou G, Ippolito GC. 2015 Next-generation sequencing and protein mass spectrometry for the comprehensive analysis of human cellular and serum antibody repertoires. Curr. Opin. Chem. Biol. 24, 112-120. (doi:10.1016/ j.cbpa.2014.11.007)
-
(2015)
Curr. Opin. Chem. Biol
, vol.24
, pp. 112-120
-
-
Lavinder, J.J.1
Horton, A.P.2
Georgiou, G.3
Ippolito, G.C.4
-
130
-
-
84886430146
-
De novo identification of VRC01 class HIV-1-neutralizing antibodies by nextgeneration sequencing of B-cell transcripts
-
Zhu J et al. 2013 De novo identification of VRC01 class HIV-1-neutralizing antibodies by nextgeneration sequencing of B-cell transcripts. Proc. Natl Acad. Sci. USA 110, E4088-E4097. (doi:10. 1073/pnas.1306262110)
-
(2013)
Proc. Natl Acad. Sci. USA
, vol.110
, pp. E4088-E4097
-
-
Zhu, J.1
-
131
-
-
84905369598
-
Cooperation of B cell lineages in induction of HIV-1-broadly neutralizing antibodies
-
Gao F et al. 2014 Cooperation of B cell lineages in induction of HIV-1-broadly neutralizing antibodies. Cell 158, 481-491. (doi:10.1016/j.cell.2014.06.022)
-
(2014)
Cell
, vol.158
, pp. 481-491
-
-
Gao, F.1
-
132
-
-
80052938385
-
Analysis of a clonal lineage of HIV-1 envelope V2/V3 conformational epitopespecific broadly neutralizing antibodies and their inferred unmutated common ancestors
-
Bonsignori M et al. 2011 Analysis of a clonal lineage of HIV-1 envelope V2/V3 conformational epitopespecific broadly neutralizing antibodies and their inferred unmutated common ancestors. J. Virol. 85, 9998-10 009. (doi:10.1128/JVI.05045-11)
-
(2011)
J. Virol
, vol.85
, pp. 9998-10 009
-
-
Bonsignori, M.1
-
133
-
-
84922740556
-
Manipulating the selection forces during affinity maturation to generate crossreactive HIV antibodies
-
Wang S et al. 2015 Manipulating the selection forces during affinity maturation to generate crossreactive HIV antibodies. Cell 160, 785-797. (doi:10. 1016/j.cell.2015.01.027)
-
(2015)
Cell
, vol.160
, pp. 785-797
-
-
Wang, S.1
-
134
-
-
84917691102
-
Antigen modification regulates competition of broad and narrow neutralizing HIV antibodies
-
McGuire AT, Dreyer AM, Carbonetti S, Lippy A, Glenn J, Scheid JF, Mouquet H, Stamatatos L. 2014 Antigen modification regulates competition of broad and narrow neutralizing HIV antibodies. Science 346, 1380-1383. (doi:10.1126/science.1259206)
-
(2014)
Science
, vol.346
, pp. 1380-1383
-
-
McGuire, A.T.1
Dreyer, A.M.2
Carbonetti, S.3
Lippy, A.4
Glenn, J.5
Scheid, J.F.6
Mouquet, H.7
Stamatatos, L.8
-
135
-
-
84907033460
-
Simulation of B cell affinity maturation explains enhanced antibody cross-reactivity induced by the polyvalent malaria vaccine AMA1
-
Chaudhury S, Reifman J, Wallqvist A. 2014 Simulation of B cell affinity maturation explains enhanced antibody cross-reactivity induced by the polyvalent malaria vaccine AMA1. J. Immunol. 193, 2073-2086. (doi:10.4049/jimmunol.1401054)
-
(2014)
J. Immunol
, vol.193
, pp. 2073-2086
-
-
Chaudhury, S.1
Reifman, J.2
Wallqvist, A.3
-
136
-
-
0019411535
-
Expression of influenza A virus internal antigens on the surface of infected P815 cells
-
Yewdell JW, Frank E, Gerhard W. 1981 Expression of influenza A virus internal antigens on the surface of infected P815 cells. J. Immunol. 126, 1814-1819.
-
(1981)
J. Immunol
, vol.126
, pp. 1814-1819
-
-
Yewdell, J.W.1
Frank, E.2
Gerhard, W.3
-
137
-
-
84880902923
-
In vitro assessment of the immunological significance of a human monoclonal antibody directed to the influenza A virus nucleoprotein
-
Bodewes R, Geelhoed-Mieras MM, Wrammert J, Ahmed R, Wilson PC, Fouchier RAM, Osterhaus ADME, Rimmelzwaan GF. 2013 In vitro assessment of the immunological significance of a human monoclonal antibody directed to the influenza A virus nucleoprotein. Clin. Vaccine Immunol. 20, 1333-1337. (doi:10.1128/CVI.00339-13)
-
(2013)
Clin. Vaccine Immunol
, vol.20
, pp. 1333-1337
-
-
Bodewes, R.1
Geelhoed-Mieras, M.M.2
Wrammert, J.3
Ahmed, R.4
Wilson, P.C.5
Fouchier, R.A.M.6
Osterhaus, A.D.M.E.7
Rimmelzwaan, G.F.8
-
138
-
-
84922619699
-
Class-switched memory B cells remodel BCRs within secondary germinal centers
-
McHeyzer-Williams LJ, Milpied PJ, Okitsu SL, McHeyzer-Williams MG. 2015 Class-switched memory B cells remodel BCRs within secondary germinal centers. Nat. Immunol. 16, 296-305. (doi:10.1038/ni.3095)
-
(2015)
Nat. Immunol
, vol.16
, pp. 296-305
-
-
McHeyzer-Williams, L.J.1
Milpied, P.J.2
Okitsu, S.L.3
McHeyzer-Williams, M.G.4
-
139
-
-
84898492241
-
Using a combined computational-experimental approach to predict antibody-specific B cell epitopes
-
Sela-Culang I et al. 2014 Using a combined computational-experimental approach to predict antibody-specific B cell epitopes. Structure 22, 646-657. (doi:10.1016/j.str.2014.02.003)
-
(2014)
Structure
, vol.22
, pp. 646-657
-
-
Sela-Culang, I.1
-
140
-
-
84923177364
-
The fitness landscape of HIV-1 gag: Advanced modeling approaches and validation of model predictions by in vitro testing
-
Mann JK, Barton JP, Ferguson AL, Omarjee S, Walker BD, Chakraborty A, Ndung T. 2014 The fitness landscape of HIV-1 gag: advanced modeling approaches and validation of model predictions by in vitro testing. PLoS Comput. Biol. 10, e1003776. (doi:10.1371/journal.pcbi.1003776)
-
(2014)
PLoS Comput. Biol
, vol.10
-
-
Mann, J.K.1
Barton, J.P.2
Ferguson, A.L.3
Omarjee, S.4
Walker, B.D.5
Chakraborty, A.6
Ndung, T.7
-
141
-
-
84926190765
-
Predicting vaccine responsiveness
-
Boyd SD, Jackson KJL. 2015 Predicting vaccine responsiveness. Cell Host Microbe 17, 301-307. (doi:10.1016/j.chom.2015.02.015)
-
(2015)
Cell Host Microbe
, vol.17
, pp. 301-307
-
-
Boyd, S.D.1
Jackson, K.J.L.2
-
142
-
-
84904390863
-
Pathogen evolution and the immunological niche
-
Cobey S. 2014 Pathogen evolution and the immunological niche. Ann. NY Acad. Sci. 1320, 1-15. (doi:10.1111/nyas.12493)
-
(2014)
Ann. NY Acad. Sci
, vol.1320
, pp. 1-15
-
-
Cobey, S.1
|