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Volumn 187, Issue 9, 1998, Pages 1495-1503

Sequence of the spacer in the recombination signal sequence affects V(D)j rearrangement frequency and correlates with nonrandom Vκ usage in vivo

Author keywords

[No Author keywords available]

Indexed keywords

SPACER DNA;

EID: 0032482172     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.187.9.1495     Document Type: Article
Times cited : (70)

References (46)
  • 1
    • 0023513107 scopus 로고
    • Development of the primary antibody repertoire
    • Alt, F.W., T.K. Blackwell, and G.D. Yancopoulos. 1987. Development of the primary antibody repertoire. Science. 238:1079-1087.
    • (1987) Science , vol.238 , pp. 1079-1087
    • Alt, F.W.1    Blackwell, T.K.2    Yancopoulos, G.D.3
  • 2
    • 0020534965 scopus 로고
    • Somatic generation of antibody diversity
    • Tonegawa, S. 1983. Somatic generation of antibody diversity. Nature. 14:575-581.
    • (1983) Nature , vol.14 , pp. 575-581
    • Tonegawa, S.1
  • 6
    • 0023054151 scopus 로고
    • H gene family utilization in colonies derived from B and pre-B cells detected by the RNA colony blot assay
    • H gene family utilization in colonies derived from B and pre-B cells detected by the RNA colony blot assay. EMBO (Eur. Mol. Biol. Organ.) J. 5:3475.
    • (1986) EMBO (Eur. Mol. Biol. Organ.) J. , vol.5 , pp. 3475
    • Wu, G.E.1    Paige, C.J.2
  • 7
    • 0022773519 scopus 로고
    • VHDJH formation and DJH replacement during pre-B differentiation: Non-random usage of gene segments
    • Reth, M.G., S. Jackson, and F.W. Alt. 1986. VHDJH formation and DJH replacement during pre-B differentiation: non-random usage of gene segments. EMBO (Eur. Mol. Biol. Organ.) J. 5:2131-2138.
    • (1986) EMBO (Eur. Mol. Biol. Organ.) J. , vol.5 , pp. 2131-2138
    • Reth, M.G.1    Jackson, S.2    Alt, F.W.3
  • 8
    • 0023184166 scopus 로고
    • H families in adult C57BL/6 and BALB/c mice
    • H families in adult C57BL/6 and BALB/c mice. J. Exp. Med. 166:163-172.
    • (1987) J. Exp. Med. , vol.166 , pp. 163-172
    • Schulze, D.H.1    Kelsoe, G.2
  • 9
    • 0023722178 scopus 로고
    • Comparison of the fetal and adult functional B cell repertoires by analysis of VH gene family expression
    • Jeong, H.D., and J.M. Teale. 1988. Comparison of the fetal and adult functional B cell repertoires by analysis of VH gene family expression. J. Exp. Med. 168:589-603.
    • (1988) J. Exp. Med. , vol.168 , pp. 589-603
    • Jeong, H.D.1    Teale, J.M.2
  • 11
    • 0024461281 scopus 로고
    • Expression of antibody V-regions is genetically and developmentally controlled and modulated by the B lymphocyte environment
    • Freitas, A.A., M.-P. Lembezat, and A. Coutinho. 1989. Expression of antibody V-regions is genetically and developmentally controlled and modulated by the B lymphocyte environment. Int. Immunol. 1:342-354.
    • (1989) Int. Immunol. , vol.1 , pp. 342-354
    • Freitas, A.A.1    Lembezat, M.-P.2    Coutinho, A.3
  • 13
    • 0025198395 scopus 로고
    • Selection of VH gene repertoires: Differentiating B cells of adult bone marrow mimic fetal development
    • Freitas, A.A., L. Andrade, M.-P. Lembezat, and A. Coutinho. 1990. Selection of VH gene repertoires: differentiating B cells of adult bone marrow mimic fetal development. Int. Immunol. 2:15-23.
    • (1990) Int. Immunol. , vol.2 , pp. 15-23
    • Freitas, A.A.1    Andrade, L.2    Lembezat, M.-P.3    Coutinho, A.4
  • 16
    • 0027333350 scopus 로고
    • A role for a pre-T-cell receptor in T-cell development
    • Groettrup, M., and H. von Boehmer. 1493. A role for a pre-T-cell receptor in T-cell development. Immunol. Today. 14:610-614.
    • (1493) Immunol. Today , vol.14 , pp. 610-614
    • Groettrup, M.1    Von Boehmer, H.2
  • 17
    • 0030765923 scopus 로고    scopus 로고
    • Changes in the VH gene repertoire of developing precursor B lymphocytes in mouse bone marrow mediated by the pre-B cell receptor
    • ten Boekel, E., F. Melchers, and A.G. Rolink. 1997. Changes in the VH gene repertoire of developing precursor B lymphocytes in mouse bone marrow mediated by the pre-B cell receptor. Immunity. 7:357-368.
    • (1997) Immunity , vol.7 , pp. 357-368
    • Ten Boekel, E.1    Melchers, F.2    Rolink, A.G.3
  • 18
    • 0027428398 scopus 로고
    • Expressed human immunoglobulin κ genes and their hypermutation
    • Klein, R., R. Jaenichen, and H.G. Zachau. 1993. Expressed human immunoglobulin κ genes and their hypermutation. Eur. J. Immunol. 23:3248-3271.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 3248-3271
    • Klein, R.1    Jaenichen, R.2    Zachau, H.G.3
  • 20
    • 0031569544 scopus 로고    scopus 로고
    • Human cord blood κ repertoire
    • Feeney, A.J., G. Lugo, and G. Escuro. 1997. Human cord blood κ repertoire. J. Immunol. 158:3761-3768.
    • (1997) J. Immunol. , vol.158 , pp. 3761-3768
    • Feeney, A.J.1    Lugo, G.2    Escuro, G.3
  • 21
    • 0026612430 scopus 로고
    • Q52 is determined by the primary DNA sequence and is largely dependent on recombination signal sequences
    • Q52 is determined by the primary DNA sequence and is largely dependent on recombination signal sequences. Eur. J. Immunol. 22:2225-2230.
    • (1992) Eur. J. Immunol. , vol.22 , pp. 2225-2230
    • Suzuki, H.1    Shiku, H.2
  • 22
    • 0025788230 scopus 로고
    • Mouse κ light-chain recombination signal sequences mediate recombination more frequently than do those of λ light chain
    • Ramsden, D.A., and G.E. Wu. 1991. Mouse κ light-chain recombination signal sequences mediate recombination more frequently than do those of λ light chain. Proc. Natl. Natl. Sci. USA. 88:10721-10725.
    • (1991) Proc. Natl. Natl. Sci. USA , vol.88 , pp. 10721-10725
    • Ramsden, D.A.1    Wu, G.E.2
  • 24
    • 0023475193 scopus 로고
    • Two pairs of recombination signals are sufficient to cause immunoglobulin V-(D)-J joining
    • Akira, S., K. Okazaki, and H. Sakano. 1987. Two pairs of recombination signals are sufficient to cause immunoglobulin V-(D)-J joining. Science. 238:1134-1138.
    • (1987) Science , vol.238 , pp. 1134-1138
    • Akira, S.1    Okazaki, K.2    Sakano, H.3
  • 25
    • 0024691453 scopus 로고
    • V(D)J recombination: A functional definition of the joining signals
    • Hesse, J.E., M.R. Lieber, K. Mizuuchi, and M. Gellert. 1989. V(D)J recombination: a functional definition of the joining signals. Genes Dev. 3:1053-1061.
    • (1989) Genes Dev. , vol.3 , pp. 1053-1061
    • Hesse, J.E.1    Lieber, M.R.2    Mizuuchi, K.3    Gellert, M.4
  • 27
    • 0027465704 scopus 로고
    • Lymphoid V(D)J recombination
    • Wei, Z., and M.R. Lieber. 1993. Lymphoid V(D)J recombination. J. Biol. Chem. 268:3180-3183.
    • (1993) J. Biol. Chem. , vol.268 , pp. 3180-3183
    • Wei, Z.1    Lieber, M.R.2
  • 28
    • 0030004660 scopus 로고    scopus 로고
    • Mouse RSS spacer sequences affect the rate of V(D)J recombination
    • Fanning, L., A. Connor, K. Baetz, D. Ramsden, and G.E. Wu. 1996. Mouse RSS spacer sequences affect the rate of V(D)J recombination. Immunogenetics. 44:146-150.
    • (1996) Immunogenetics , vol.44 , pp. 146-150
    • Fanning, L.1    Connor, A.2    Baetz, K.3    Ramsden, D.4    Wu, G.E.5
  • 29
    • 0028351920 scopus 로고
    • Level of human TCRBV3S1 (Vβ3) expression correlates with allelic polymorphism in the spacer region of the recombination signal sequence
    • Posnett, D.N., C.S. Vissinga, C. Pambuccian, S. Wei, M.A. Robinson, D. Kostyu, and P. Cancannon. 1994. Level of human TCRBV3S1 (Vβ3) expression correlates with allelic polymorphism in the spacer region of the recombination signal sequence. J. Exp. Med. 179:1707-1711.
    • (1994) J. Exp. Med. , vol.179 , pp. 1707-1711
    • Posnett, D.N.1    Vissinga, C.S.2    Pambuccian, C.3    Wei, S.4    Robinson, M.A.5    Kostyu, D.6    Cancannon, P.7
  • 31
    • 0024820851 scopus 로고
    • Sequence and fine specificity analysis of primary 511 anti-phosphorylcholine antibodies
    • Feeney, A.J., and D. Thuerauf. 1989. Sequence and fine specificity analysis of primary 511 anti-phosphorylcholine antibodies. J. Immunol. 143:4061-4068.
    • (1989) J. Immunol. , vol.143 , pp. 4061-4068
    • Feeney, A.J.1    Thuerauf, D.2
  • 32
    • 0029116259 scopus 로고
    • Somatic mutation and CDR3 lengths of immunoglobulin K light chains expressed in patients with rheumatoid arthritis and in normal individuals
    • Bridges, S.L., Jr., S.K. Lee, M.L. Johnson, J.C. Lavelle, P.G. Fowler, W.J. Koopman, and H.W. Schroeder, Jr. 1995. Somatic mutation and CDR3 lengths of immunoglobulin K light chains expressed in patients with rheumatoid arthritis and in normal individuals. J. Clin. Invest. 96:831-841.
    • (1995) J. Clin. Invest. , vol.96 , pp. 831-841
    • Bridges Jr., S.L.1    Lee, S.K.2    Johnson, M.L.3    Lavelle, J.C.4    Fowler, P.G.5    Koopman, W.J.6    Schroeder Jr., H.W.7
  • 34
  • 36
    • 0028291092 scopus 로고
    • Conservation of sequence in recombination signal sequence spacers
    • Ramsden, D.A., K. Baetz, and G.E. Wu. 1994. Conservation of sequence in recombination signal sequence spacers. Nucleic Acids Res. 22:1785-1796.
    • (1994) Nucleic Acids Res. , vol.22 , pp. 1785-1796
    • Ramsden, D.A.1    Baetz, K.2    Wu, G.E.3
  • 37
    • 0026507505 scopus 로고
    • CpG methylated minichromosomes become inaccessible for V(D)J recombination after undergoing replication
    • Hsieh, C.-L., and M.R. Lieber. 1992. CpG methylated minichromosomes become inaccessible for V(D)J recombination after undergoing replication. EMBO (Eur. Mol. Biol. Organ.) J. 11:315-325.
    • (1992) EMBO (Eur. Mol. Biol. Organ.) J. , vol.11 , pp. 315-325
    • Hsieh, C.-L.1    Lieber, M.R.2
  • 38
    • 0027396509 scopus 로고
    • Influence of CpG methylation and target spacing on V(D)J recombination in a transgenic substrate
    • Engler, P., A. Weng, and U. Storb. 1993. Influence of CpG methylation and target spacing on V(D)J recombination in a transgenic substrate. Mol. Cell. Biol. 13:571-577.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 571-577
    • Engler, P.1    Weng, A.2    Storb, U.3
  • 40
    • 0029664445 scopus 로고    scopus 로고
    • κA2 allele in Navajos which may play a role in increased susceptibility to Haemophilus influenzae type b disease
    • κA2 allele in Navajos which may play a role in increased susceptibility to Haemophilus influenzae type b disease. J. Clin. Invest. 97:2277-2282.
    • (1996) J. Clin. Invest. , vol.97 , pp. 2277-2282
    • Feeney, A.J.1    Atkinson, M.J.2    Cowan, M.J.3    Escuro, G.4    Lugo, G.5
  • 41
    • 0027237601 scopus 로고
    • Coding end sequence can markedly affect the initiation of V(D)J recombination
    • Gerstein, R.M., and M.R. Lieber. 1993. Coding end sequence can markedly affect the initiation of V(D)J recombination. Genes Dev. 7:1459-1469.
    • (1993) Genes Dev. , vol.7 , pp. 1459-1469
    • Gerstein, R.M.1    Lieber, M.R.2
  • 42
    • 0027495670 scopus 로고
    • V(D)J recombination coding junction formation without DNA homology: Processing of coding termini
    • Boubnov, N.V., Z.P. Wills, and D.T. Weaver. 1993. V(D)J recombination coding junction formation without DNA homology: processing of coding termini. Mol. Cell. Biol. 13: 6957-6968.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 6957-6968
    • Boubnov, N.V.1    Wills, Z.P.2    Weaver, D.T.3
  • 43
    • 0028956147 scopus 로고
    • Asymmetric processing of coding ends and the effect of coding end nucleotide composition on V(D)J recombination
    • Ezekiel, U.R., P. Engler, D. Stern, and U. Storb. 1995. Asymmetric processing of coding ends and the effect of coding end nucleotide composition on V(D)J recombination. Immunity. 2:381-389.
    • (1995) Immunity , vol.2 , pp. 381-389
    • Ezekiel, U.R.1    Engler, P.2    Stern, D.3    Storb, U.4
  • 44
    • 0030984706 scopus 로고    scopus 로고
    • The composition of coding joints formed in V(D)J recombination is strongly affected by the nucleotide sequence of the coding ends and their relationship to the recombination signal sequences
    • Ezekiel, U.R., T. Sun, G. Bozek, and U. Storb. 1997. The composition of coding joints formed in V(D)J recombination is strongly affected by the nucleotide sequence of the coding ends and their relationship to the recombination signal sequences. Mol. Cell. Biol. 17:4191-4197.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 4191-4197
    • Ezekiel, U.R.1    Sun, T.2    Bozek, G.3    Storb, U.4
  • 45
    • 0030293631 scopus 로고    scopus 로고
    • Immunoglobulin DH recombination signal sequence targeting. Effect of DH coding and flanking regions and recombination partner
    • VanDyk, L.F., T.W. Wise, B.B. Moore, and K. Meek. 1996. Immunoglobulin DH recombination signal sequence targeting. Effect of DH coding and flanking regions and recombination partner. J. Immunol. 157:4005-4015.
    • (1996) J. Immunol. , vol.157 , pp. 4005-4015
    • VanDyk, L.F.1    Wise, T.W.2    Moore, B.B.3    Meek, K.4
  • 46
    • 0030788616 scopus 로고    scopus 로고
    • V(D)J recombination frequency is affected by the sequence interposed between a pair of recombination signals: Sequence comparison reveals a putative recombinational enhancer element
    • Roch, F.A., R. Hobi, M.W. Berchtold, and C.C. Kuenzle. 1997. V(D)J recombination frequency is affected by the sequence interposed between a pair of recombination signals: sequence comparison reveals a putative recombinational enhancer element. Nucleic Acids Res. 25:2303-2310.
    • (1997) Nucleic Acids Res. , vol.25 , pp. 2303-2310
    • Roch, F.A.1    Hobi, R.2    Berchtold, M.W.3    Kuenzle, C.C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.