Intricate targeting of immunoglobulin somatic hypermutation maximizes the efficiency of affinity maturation

Journal of Experimental Medicine

Volumn 201, Issue 9, 2005, Pages 1467-1478

  Zheng, Nai Ying ^a   Wilson, Kenneth ^a   Jared, Matthew ^a   Wilson, Patrick C ^a  

^a OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTIDINE DEAMINASE; DNA POLYMERASE;

ARTICLE; BASE MISPAIRING; CODON USAGE; CONTROLLED STUDY; DEAMINATION; EXCISION REPAIR; GENE SEQUENCE; GENE TARGETING; IMMUNOGLOBULIN GENE; IMMUNOGLOBULIN VARIABLE REGION; NUCLEIC ACID BASE SUBSTITUTION; PRIORITY JOURNAL; SOMATIC MUTATION;

B-LYMPHOCYTES; BASE SEQUENCE; CODON; CYTIDINE DEAMINASE; CYTOSINE DEAMINASE; DNA REPAIR; DNA-DIRECTED DNA POLYMERASE; EVOLUTION, MOLECULAR; FLOW CYTOMETRY; HUMANS; IMMUNOGLOBULIN VARIABLE REGION; MOLECULAR SEQUENCE DATA; MUTATION; SEQUENCE ANALYSIS, DNA; SOMATIC HYPERMUTATION, IMMUNOGLOBULIN;

EID: 18644366944     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20042483     Document Type: Article

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