Resistance is not futile: Gliotoxin biosynthesis, functionality and utility

Trends in Microbiology

Volumn 23, Issue 7, 2015, Pages 419-428

  Dolan, Stephen K ^a   O'Keeffe, Grainne ^a   Jones, Gary W ^a   Doyle, Sean ^a  

^a NATIONAL UNIVERSITY OF IRELAND   (Ireland)

Author keywords

Antioxidant; Aspergillus fumigatus; Natural products; NRPS; Secondary metabolism

Indexed keywords

GLIOTOXIN; GLUTATHIONE; HISTONE H3K9 METHYLTRANSFERASE; HISTONE METHYLTRANSFERASE; UNCLASSIFIED DRUG; BIOLOGICAL PRODUCT; FUNGAL PROTEIN;

APOPTOSIS; ASPERGILLUS FUMIGATUS; BIOSYNTHESIS; CYTOTOXICITY; DISULFIDE BOND; ENZYME INHIBITION; GENE; GENE EXPRESSION; GLI GENE; HISTONE METHYLATION; MICROBIAL SENSITIVITY TEST; MOLECULAR INTERACTION; NONHUMAN; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; PEST RESISTANCE; PRIORITY JOURNAL; PROTEIN DEGRADATION; REGULATORY MECHANISM; REVIEW; ANIMAL; CHEMISTRY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; METABOLOME; MULTIGENE FAMILY; PATHOGENICITY; PHYSIOLOGY;

ANIMALIA; ASPERGILLUS FUMIGATUS; EUKARYOTA; FUNGI;

ANIMALS; ASPERGILLUS FUMIGATUS; BIOLOGICAL PRODUCTS; FUNGAL PROTEINS; GENE EXPRESSION REGULATION, FUNGAL; GLIOTOXIN; METABOLOME; MULTIGENE FAMILY;

EID: 84937631505     PISSN: 0966842X     EISSN: 18784380     Source Type: Journal    
DOI: 10.1016/j.tim.2015.02.005     Document Type: Review

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