Mechanistic and chiroptical studies on the desulfurization of epidithiodioxopiperazines reveal universal retention of configuration at the bridgehead carbon atoms

Journal of Organic Chemistry

Volumn 78, Issue 23, 2013, Pages 11646-11655

  Cherblanc, Fanny L ^a   Lo, Ya Pei ^a   Herrebout, Wouter A ^b,d   Bultinck, Patrick ^c,d   Rzepa, Henry S ^a   Fuchter, Matthew J ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF ANTWERP   (Belgium)

^c GHENT UNIVERSITY   (Belgium)

^d European Centre for Chirality   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON ATOMS; CHEMICAL DERIVATIZATION; COMPUTATIONAL STUDIES; ELECTRONIC CIRCULAR DICHROISM; INVERSION OF CONFIGURATION; MECHANISTIC PATHWAYS; STEREOCHEMICAL PATHWAYS; VIBRATIONAL CIRCULAR DICHROISM SPECTRUM;

DICHROISM; STEREOCHEMISTRY;

DESULFURIZATION;

3,6 EPIDITHIODIOXOPIPERAZINE; CARBON; GLIOTOXIN; PIPERAZINE DERIVATIVE; PIPERAZINEDIONE; TRIPHENYLPHOSPHINE; UNCLASSIFIED DRUG;

ARTICLE; ATOM; CIRCULAR DICHROISM; DERIVATIZATION; DESULFURIZATION; ENANTIOMER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; OPTICAL ROTATION; OPTICAL ROTATORY DISPERSION; QUANTUM CHEMISTRY; RACEMIZATION; RING OPENING; ROOM TEMPERATURE; STEREOCHEMISTRY; STEREOISOMERISM; X RAY CRYSTALLOGRAPHY;

CARBON; MOLECULAR CONFORMATION; PIPERAZINES; QUANTUM THEORY; SULFHYDRYL COMPOUNDS;

EID: 84890232045     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo401316a     Document Type: Article

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