Regulation of nonribosomal peptide synthesis: Bis-thiomethylation attenuates gliotoxin biosynthesis in Aspergillus fumigatus

Chemistry and Biology

Volumn 21, Issue 8, 2014, Pages 999-1012

  Dolan, Stephen K ^a   Owens, Rebecca A ^a   O'Keeffe, Grainne ^a   Hammel, Stephen ^a   Fitzpatrick, David A ^a   Jones, Gary W ^a   Doyle, Sean ^a  

^a NATIONAL UNIVERSITY OF IRELAND   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

2,3,5A,6 TETRAHYDRO 6 HYDROXY 3 HYDROXYMETHYL 2 METHYL 3,10A BIS(METHYLTHIO)PYRAZINO[1,2 A]INDOLE 1,4 DIONE; DITHIOGLIOTOXIN; FUNGAL ENZYME; FUNGAL PROTEIN; GLIOTOXIN; GLIOTOXIN BIS THIOMETHYLTRANSFERASE A; OXIDOREDUCTASE; PROTEIN GTMA; PROTEIN HYDROLYSATE; S ADENOSYLMETHIONINE; UNCLASSIFIED DRUG;

ARTICLE; ASCOMYCETES; ASPERGILLUS FUMIGATUS; BIOSYNTHESIS; CHEMICAL REACTION; CONTROLLED STUDY; ENZYME ACTIVITY; FUNGAL GENE; GTMA GENE; METHYLATION; NONHUMAN; NONRIBOSOMAL PEPTIDE SYNTHESIS; PHYLOGENY; PRIORITY JOURNAL; PROTEOMICS; REGULATORY MECHANISM; THIOMETHYLATION; ANALOGS AND DERIVATIVES; CHEMISTRY; CONFORMATION; ENZYMOLOGY; GENETICS; ISOLATION AND PURIFICATION; METABOLISM;

ASPERGILLUS FUMIGATUS; GLIOTOXIN; METHYLATION; MOLECULAR CONFORMATION; OXIDOREDUCTASES; PEPTIDE BIOSYNTHESIS, NUCLEIC ACID-INDEPENDENT; PHYLOGENY;

EID: 84920668030     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2014.07.006     Document Type: Article

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