The immunosuppressive fungal metabolite gliotoxin specifically inhibits transcription factor NF-κB

Journal of Experimental Medicine

Volumn 183, Issue 4, 1996, Pages 1829-1840

  Pahl, Heike L ^a   Krauß, Beate ^a   Schulze Osthof, Klaus ^a   Decker, Thomas ^b   Traenckner, E Britta Mareen ^a   Vogt, Markus ^a   Myers, Christina ^c   Parks, Tom ^c   Warring, Paul ^d   Mühlbacher, Arno ^d   Czernilofsky, Armin Peter ^e   Baeuerle, Patrick A ^a,f  

^a UNIVERSITY OF FREIBURG   (Germany)

^b Vienna Biocenter   (Austria)

^c BOEHRINGER INGELHEIM PHARMACEUTICALS INC   (United States)

^d AUSTRALIAN NATIONAL UNIVERSITY   (Australia)

^e BOEHRINGER INGELHEIM RCV GMBH AND CO KG   (Austria)

^f AMGEN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLIOTOXIN; TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; ASPERGILLOSIS; ASPERGILLUS FUMIGATUS; B LYMPHOCYTE ACTIVATION; CELL PROLIFERATION; DNA BINDING; IMMUNOSUPPRESSIVE TREATMENT; MESENTERY LYMPH NODE; NONHUMAN; OPPORTUNISTIC INFECTION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION;

CELLS, CULTURED; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; GENES, REPORTER; GLIOTOXIN; HUMANS; I-KAPPA B PROTEINS; IMMUNOSUPPRESSIVE AGENTS; INTERCELLULAR ADHESION MOLECULE-1; NF-KAPPA B; PHOSPHORYLATION; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; PROTEIN-TYROSINE KINASES; T-LYMPHOCYTES; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 15844381960     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.183.4.1829     Document Type: Article

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