메뉴 건너뛰기




Volumn 120, Issue 1, 2000, Pages 59-65

Nuclear factor-κB activity and intestinal inflammation in dextran sulphate sodium (DSS)-induced colitis in mice is suppressed by gliotoxin

Author keywords

DSS colitis; Gliotoxin; NF B

Indexed keywords

DEXTRAN SULFATE; GLIOTOXIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN;

EID: 0034024741     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.2000.01184.x     Document Type: Article
Times cited : (78)

References (48)
  • 1
    • 0028006855 scopus 로고
    • Dextran sulfate sodium-induced colitis occurs in severe combined immunodeficient mice
    • Dieleman LA, Ridwan BU, Tennyson GS et al. Dextran sulfate sodium-induced colitis occurs in severe combined immunodeficient mice. Gastroenterology 1994; 107:1643-52.
    • (1994) Gastroenterology , vol.107 , pp. 1643-1652
    • Dieleman, L.A.1    Ridwan, B.U.2    Tennyson, G.S.3
  • 2
    • 0029127778 scopus 로고
    • Experimental models of inflammatory bowel disease
    • Elson CO, Sartor RB, Tennyson GS et al. Experimental models of inflammatory bowel disease. Gastroenterology 1995; 109:1344-67.
    • (1995) Gastroenterology , vol.109 , pp. 1344-1367
    • Elson, C.O.1    Sartor, R.B.2    Tennyson, G.S.3
  • 3
    • 0032408502 scopus 로고    scopus 로고
    • Involvement of interleukin-1 in the development of ulcerative colitis induced by dextran sulfate sodium in mice
    • Arai Y, Takanashi H, Kitagawa H et al. Involvement of interleukin-1 in the development of ulcerative colitis induced by dextran sulfate sodium in mice. Cytokine 1998; 10:890-6.
    • (1998) Cytokine , vol.10 , pp. 890-896
    • Arai, Y.1    Takanashi, H.2    Kitagawa, H.3
  • 4
    • 0031763281 scopus 로고    scopus 로고
    • Mucosal immunoregulation and inflammatory bowel disease: New insights from murine models of inflammation
    • Strober W, Fuss IJ, Ehrhardt RO et al. Mucosal immunoregulation and inflammatory bowel disease: new insights from murine models of inflammation. Scand J Immunol 1998; 48:453-8.
    • (1998) Scand J Immunol , vol.48 , pp. 453-458
    • Strober, W.1    Fuss, I.J.2    Ehrhardt, R.O.3
  • 5
    • 0031914778 scopus 로고    scopus 로고
    • Cytokines in inflammatory bowel disease
    • Rogler G, Andus T. Cytokines in inflammatory bowel disease. World J Surg 1998; 22:382-9.
    • (1998) World J Surg , vol.22 , pp. 382-389
    • Rogler, G.1    Andus, T.2
  • 6
    • 0031926192 scopus 로고    scopus 로고
    • Medical therapy of inflammatory bowel disease
    • Rutgeerts P. Medical therapy of inflammatory bowel disease. Digestion 1998; 59:453-69.
    • (1998) Digestion , vol.59 , pp. 453-469
    • Rutgeerts, P.1
  • 7
    • 0031925362 scopus 로고    scopus 로고
    • Activation of nuclear factor κB in inflammatory bowel disease
    • Schreiber S, Nikolaus S, Hampe J. Activation of nuclear factor κB in inflammatory bowel disease. Gut 1998; 42:477-84.
    • (1998) Gut , vol.42 , pp. 477-484
    • Schreiber, S.1    Nikolaus, S.2    Hampe, J.3
  • 8
    • 0029836444 scopus 로고    scopus 로고
    • Local administration of antisense phosphorothiotate oligonucleotides to the p65 subunit of NF-kappa B abrogates established experimental colitis in mice
    • Neurath MF, Petterson S, Meyer zum Büschenfelde KH et al. Local administration of antisense phosphorothiotate oligonucleotides to the p65 subunit of NF-kappa B abrogates established experimental colitis in mice. Nat Med 1996; 2:998-1004.
    • (1996) Nat Med , vol.2 , pp. 998-1004
    • Neurath, M.F.1    Petterson, S.2    Meyer Zum Büschenfelde, K.H.3
  • 9
    • 0031595210 scopus 로고    scopus 로고
    • Nuclear factor-kappa B is activated in macrophages and epithelial cells of inflamed intestinal mucosa
    • Rogler G, Brand K, Vogel D et al. Nuclear factor-kappa B is activated in macrophages and epithelial cells of inflamed intestinal mucosa. Gastroenterology 1998; 115:357-69.
    • (1998) Gastroenterology , vol.115 , pp. 357-369
    • Rogler, G.1    Brand, K.2    Vogel, D.3
  • 10
    • 0029874138 scopus 로고    scopus 로고
    • The NF-kappa B and I kappa B proteins: New discoveries and insights
    • Baldwin As Jr. The NF-kappa B and I kappa B proteins: new discoveries and insights. Annu Rev Immunol 1996; 14:649-83.
    • (1996) Annu Rev Immunol , vol.14 , pp. 649-683
    • Baldwin A.S., Jr.1
  • 11
    • 0030885492 scopus 로고    scopus 로고
    • Proteasome inhibition attenuates nitric oxide synthase expression, VCAM- 1 transcription and the development of chronic colitis
    • Conner EM, Brand S, Davis JM et al. Proteasome inhibition attenuates nitric oxide synthase expression, VCAM- 1 transcription and the development of chronic colitis. J Pharmacol Exp Ther 1997; 282:1615-22.
    • (1997) J Pharmacol Exp Ther , vol.282 , pp. 1615-1622
    • Conner, E.M.1    Brand, S.2    Davis, J.M.3
  • 12
    • 0022658585 scopus 로고
    • Structural relationship of epipolythiodioxopiperazines and their immunomodulating activity
    • Mullbacher A, Waring P, Tiwari-Palni U et al. Structural relationship of epipolythiodioxopiperazines and their immunomodulating activity. Mol Immunol 1986; 23:231-5.
    • (1986) Mol Immunol , vol.23 , pp. 231-235
    • Mullbacher, A.1    Waring, P.2    Tiwari-Palni, U.3
  • 13
    • 0030561529 scopus 로고    scopus 로고
    • Gliotoxin and related epipolythiodioxopiperazines
    • Waring P, Beaver J. Gliotoxin and related epipolythiodioxopiperazines. Gen Pharmacol 1996; 27:1311-6.
    • (1996) Gen Pharmacol , vol.27 , pp. 1311-1316
    • Waring, P.1    Beaver, J.2
  • 14
    • 0011925448 scopus 로고
    • Immunosuppression in vitro by a metabolite of a human pathogenic fungus
    • Mullbacher A, Eichner RD. Immunosuppression in vitro by a metabolite of a human pathogenic fungus. Proc Natl Acad Sci USA 1984; 81:3835-7.
    • (1984) Proc Natl Acad Sci USA , vol.81 , pp. 3835-3837
    • Mullbacher, A.1    Eichner, R.D.2
  • 15
    • 0030045045 scopus 로고    scopus 로고
    • Suppressive effects of Aspergillus fumigatus culture filtrates on human alveolar macrophages and polymorphonuclear leucocytes
    • Murayama T, Amitani R, Ikegami Y et al. Suppressive effects of Aspergillus fumigatus culture filtrates on human alveolar macrophages and polymorphonuclear leucocytes. Eur Respir J 1996; 9:293-300.
    • (1996) Eur Respir J , vol.9 , pp. 293-300
    • Murayama, T.1    Amitani, R.2    Ikegami, Y.3
  • 16
    • 15844381960 scopus 로고    scopus 로고
    • The immunosuppressive fungal metabolite gliotoxin specifically inhibits transcription factor NF-kappaB
    • Pahl HL, Krauss B, Schulze OK et al. The immunosuppressive fungal metabolite gliotoxin specifically inhibits transcription factor NF-kappaB. J Exp Med 1996; 183:1829-40.
    • (1996) J Exp Med , vol.183 , pp. 1829-1840
    • Pahl, H.L.1    Krauss, B.2    Schulze, O.K.3
  • 17
    • 0031015257 scopus 로고    scopus 로고
    • Neutralization of tumour necrosis factor (TNF) but not of IL-1 reduces inflammation in chronic dextran sulphate sodium-induced colitis in mice
    • Kojouharoff G, Hans W, Obermeier F et al. Neutralization of tumour necrosis factor (TNF) but not of IL-1 reduces inflammation in chronic dextran sulphate sodium-induced colitis in mice. Clin Exp Immunol 1997; 107:353-8.
    • (1997) Clin Exp Immunol , vol.107 , pp. 353-358
    • Kojouharoff, G.1    Hans, W.2    Obermeier, F.3
  • 18
    • 0019997889 scopus 로고
    • Cellular and extracellular myeloperoxidase in pyogenic inflammation
    • Bradley PP, Christensen RD, Rothstein G. Cellular and extracellular myeloperoxidase in pyogenic inflammation. Blood 1982; 60:618-22.
    • (1982) Blood , vol.60 , pp. 618-622
    • Bradley, P.P.1    Christensen, R.D.2    Rothstein, G.3
  • 19
    • 0030480323 scopus 로고    scopus 로고
    • Interleukin-10 suppresses chronic granulomatous inflammation induced by bacterial cell wall polymers in a rat model
    • Herfarth HH, Mohanty SP, Rath HC et al. Interleukin-10 suppresses chronic granulomatous inflammation induced by bacterial cell wall polymers in a rat model. Gut 1996; 39:836-45.
    • (1996) Gut , vol.39 , pp. 836-845
    • Herfarth, H.H.1    Mohanty, S.P.2    Rath, H.C.3
  • 20
    • 0022861668 scopus 로고
    • A procedure for Northern blot analysis of native RNA
    • Khandjian EW, Meric C. A procedure for Northern blot analysis of native RNA. Anal Biochem 1986; 159:227-32.
    • (1986) Anal Biochem , vol.159 , pp. 227-232
    • Khandjian, E.W.1    Meric, C.2
  • 21
    • 0022484665 scopus 로고
    • UV crosslinking of RNA to nylon membrane enhances hybridization signals
    • Khandjian EW. UV crosslinking of RNA to nylon membrane enhances hybridization signals. Mol Biol Rep 1986; 11:107-15.
    • (1986) Mol Biol Rep , vol.11 , pp. 107-115
    • Khandjian, E.W.1
  • 22
    • 13344261982 scopus 로고    scopus 로고
    • Activated transcription factor nuclear factor-kappa B is present in the atherosclerotic lesion
    • Brand K, Page S, Rogler G et al. Activated transcription factor nuclear factor-kappa B is present in the atherosclerotic lesion. J Clin Invest 1996; 97:1715-22.
    • (1996) J Clin Invest , vol.97 , pp. 1715-1722
    • Brand, K.1    Page, S.2    Rogler, G.3
  • 23
    • 0028264950 scopus 로고
    • In vivo immunosuppressive activity of gliotoxin, a metabolite produced by human pathogenic fungi
    • Sutton P, Newcombe NR, Waring P et al. In vivo immunosuppressive activity of gliotoxin, a metabolite produced by human pathogenic fungi. Infect Immun 1994; 62:1192-8.
    • (1994) Infect Immun , vol.62 , pp. 1192-1198
    • Sutton, P.1    Newcombe, N.R.2    Waring, P.3
  • 25
    • 0026025630 scopus 로고
    • Expression of leukocyte adhesion molecules by mucosal mononuclear phagocytes in inflammatory bowel disease
    • Malizia G, Calabrese A, Cottone M et al. Expression of leukocyte adhesion molecules by mucosal mononuclear phagocytes in inflammatory bowel disease. Gastroenterology 1991; 100:150-9.
    • (1991) Gastroenterology , vol.100 , pp. 150-159
    • Malizia, G.1    Calabrese, A.2    Cottone, M.3
  • 26
    • 0027424953 scopus 로고
    • Altered expression of cell adhesion molecules in uninvolved gut in inflammatory bowel disease
    • Schuermann GM, Aber BA, Facer P et al. Altered expression of cell adhesion molecules in uninvolved gut in inflammatory bowel disease. Clin Exp Immunol 1993; 94:341-7.
    • (1993) Clin Exp Immunol , vol.94 , pp. 341-347
    • Schuermann, G.M.1    Aber, B.A.2    Facer, P.3
  • 27
    • 0030071347 scopus 로고    scopus 로고
    • Interleukin 8: Cells of origin in inflammatory bowel disease
    • Grimm MC, Elsbury S, Pavli P et al. Interleukin 8: cells of origin in inflammatory bowel disease. Gut 1996; 38:90-98.
    • (1996) Gut , vol.38 , pp. 90-98
    • Grimm, M.C.1    Elsbury, S.2    Pavli, P.3
  • 28
    • 0030067724 scopus 로고
    • Increased interleukin 8 expression in the colon mucosa of patients with inflammatory bowel disease
    • Daig R, Andus T, Aschenbrenner E et al. Increased interleukin 8 expression in the colon mucosa of patients with inflammatory bowel disease. Gut 1995; 38:216-22.
    • (1995) Gut , vol.38 , pp. 216-222
    • Daig, R.1    Andus, T.2    Aschenbrenner, E.3
  • 29
    • 0030041142 scopus 로고    scopus 로고
    • Differential in situ expression of the genes encoding the chemokines MCP-1 and RANTES in human inflammatory bowel disease
    • Mazzucchelli L, Hauser C, Zgraggen K et al. Differential in situ expression of the genes encoding the chemokines MCP-1 and RANTES in human inflammatory bowel disease. J Pathol 1996; 178:201-6.
    • (1996) J Pathol , vol.178 , pp. 201-206
    • Mazzucchelli, L.1    Hauser, C.2    Zgraggen, K.3
  • 30
    • 0028813487 scopus 로고
    • Monocyte-chemoattractant protein 1 gene expression in intestinal epithelial cells and inflammatory bowel disease mucosa
    • Reinecker H-C, Loh EY, Ringler DJ et al. Monocyte-chemoattractant protein 1 gene expression in intestinal epithelial cells and inflammatory bowel disease mucosa. Gastroenterology 1995; 108:40-50.
    • (1995) Gastroenterology , vol.108 , pp. 40-50
    • Reinecker, H.-C.1    Loh, E.Y.2    Ringler, D.J.3
  • 31
    • 0031573593 scopus 로고    scopus 로고
    • A role for TNF-alpha and mucosal T helper-1 cytokines in the pathogenesis of Crohn's disease
    • Plevy SE, Landers CJ, Prehn J et al. A role for TNF-alpha and mucosal T helper-1 cytokines in the pathogenesis of Crohn's disease. J Immunol 1997; 159:6276-82.
    • (1997) J Immunol , vol.159 , pp. 6276-6282
    • Plevy, S.E.1    Landers, C.J.2    Prehn, J.3
  • 32
    • 0024344814 scopus 로고
    • Enhanced production of interleukin-1β by mononuclear cells isolated from mucosa with active ulcerative colitis and Crohn's disease
    • Mahida YR, Wu K, Jewell DP. Enhanced production of interleukin-1β by mononuclear cells isolated from mucosa with active ulcerative colitis and Crohn's disease. Gut 1989; 30:835-8.
    • (1989) Gut , vol.30 , pp. 835-838
    • Mahida, Y.R.1    Wu, K.2    Jewell, D.P.3
  • 33
    • 0025181580 scopus 로고
    • A novel method in the induction of reliable experimental acute and chronic ulcerative colitis in mice
    • Okayasu I, Hatakeyma S, Yamada M et al. A novel method in the induction of reliable experimental acute and chronic ulcerative colitis in mice. Gastroenterology 1990; 98:694-702.
    • (1990) Gastroenterology , vol.98 , pp. 694-702
    • Okayasu, I.1    Hatakeyma, S.2    Yamada, M.3
  • 34
    • 0031945843 scopus 로고    scopus 로고
    • Differential susceptibility of inbred mouse strains to dextran sulfate sodium-induced colitis
    • Mahler M, Bristol IJ, Leiter EH et al. Differential susceptibility of inbred mouse strains to dextran sulfate sodium-induced colitis. Am J Physiol 1998; 274:G544-G551.
    • (1998) Am J Physiol , vol.274
    • Mahler, M.1    Bristol, I.J.2    Leiter, E.H.3
  • 35
    • 0001561524 scopus 로고    scopus 로고
    • Colonic antioxidant status in dextran sulfate-induced colitis in mice
    • Blackburn AC, Doe WF, Buffinton GD. Colonic antioxidant status in dextran sulfate-induced colitis in mice. Inflamm Bowel Dis 1997; 3:198-203.
    • (1997) Inflamm Bowel Dis , vol.3 , pp. 198-203
    • Blackburn, A.C.1    Doe, W.F.2    Buffinton, G.D.3
  • 36
    • 0031897632 scopus 로고    scopus 로고
    • NF-kappa B and Rel proteins: Evolutionarily conserved mediators of immune responses
    • Ghosh S, May MJ, Kopp EB. NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses. Annu Rev Immunol 1998; 16:225-60.
    • (1998) Annu Rev Immunol , vol.16 , pp. 225-260
    • Ghosh, S.1    May, M.J.2    Kopp, E.B.3
  • 37
    • 0001535050 scopus 로고    scopus 로고
    • In vivo treatment with the fungal metabolite gliotoxin suppresses intestinal inflammation in dextran sulphate sodium [DSS]-induced colitis
    • Abstr.
    • Herfarth H, Rath HC, Hofmeister R et al. In vivo treatment with the fungal metabolite gliotoxin suppresses intestinal inflammation in dextran sulphate sodium [DSS]-induced colitis. Gastroenterology 1998; 114:A993(Abstr.).
    • (1998) Gastroenterology , vol.114
    • Herfarth, H.1    Rath, H.C.2    Hofmeister, R.3
  • 38
    • 4243518362 scopus 로고    scopus 로고
    • Immunosuppressive effect of treatment with the fungal metabolite gliotoxin in dextran sulphate sodium [DSS]-induced colitis
    • Abstr.
    • Herfarth H, Brand K, Rogler G et al. Immunosuppressive effect of treatment with the fungal metabolite gliotoxin in dextran sulphate sodium [DSS]-induced colitis. Gastroenterology 1999; 116:A3086(Abstr.).
    • (1999) Gastroenterology , vol.116
    • Herfarth, H.1    Brand, K.2    Rogler, G.3
  • 39
    • 0031434763 scopus 로고    scopus 로고
    • Predominant role of NF-B p65 in the pathogenesis of chronic intestinal inflammation
    • Neurath MF, Petterson S. Predominant role of NF-B p65 in the pathogenesis of chronic intestinal inflammation. Immunobiol 1997; 198:91-98.
    • (1997) Immunobiol , vol.198 , pp. 91-98
    • Neurath, M.F.1    Petterson, S.2
  • 40
    • 0030615201 scopus 로고    scopus 로고
    • Nuclear factor-kappaB: A pivotal transcription factor in chronic inflammatory diseases
    • Barnes PJ, Karin M. Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases. N Engl J Med 1997; 336:1066-71.
    • (1997) N Engl J Med , vol.336 , pp. 1066-1071
    • Barnes, P.J.1    Karin, M.2
  • 41
    • 0031932422 scopus 로고    scopus 로고
    • Inhibition of proinflammatory molecule production by adenovirus-mediated expression of a nuclear factor kappaB super-repressor in human intestinal epithelial cells
    • Jobin C, Panja A, Hellerbrand C et al. Inhibition of proinflammatory molecule production by adenovirus-mediated expression of a nuclear factor kappaB super-repressor in human intestinal epithelial cells. J Immunol 1998; 160:410-8.
    • (1998) J Immunol , vol.160 , pp. 410-418
    • Jobin, C.1    Panja, A.2    Hellerbrand, C.3
  • 42
    • 0031808369 scopus 로고    scopus 로고
    • Mediation by NF-kappa B of cytokine induced expression of intercellular adhesion molecule 1 (ICAM-1) in an intestinal epithelial cell line, a process blocked by proteasome inhibitors
    • Jobin C, Hellerbrand C, Licato LL et al. Mediation by NF-kappa B of cytokine induced expression of intercellular adhesion molecule 1 (ICAM-1) in an intestinal epithelial cell line, a process blocked by proteasome inhibitors. Gut 1998; 42:779-87.
    • (1998) Gut , vol.42 , pp. 779-787
    • Jobin, C.1    Hellerbrand, C.2    Licato, L.L.3
  • 43
    • 0032433179 scopus 로고    scopus 로고
    • Molecular mechanisms involved in NSAID-induced gastropathy
    • Morise Z, Grisham MB. Molecular mechanisms involved in NSAID-induced gastropathy. J Clin Gastroenterol 1998; 27:S87-S90.
    • (1998) J Clin Gastroenterol , vol.27
    • Morise, Z.1    Grisham, M.B.2
  • 44
    • 0013646514 scopus 로고    scopus 로고
    • ICAM-1 antibody treatment reduces leukocyte adherence and extravasation in DSS-induced colitis in mice: Assessment by in vivo fluorescence microscopy
    • Farkas S, Herfarth H, Cuba M et al. ICAM-1 antibody treatment reduces leukocyte adherence and extravasation in DSS-induced colitis in mice: assessment by in vivo fluorescence microscopy. Langenbecks Arch Surg Suppl 1999; 1:403-6.
    • (1999) Langenbecks Arch Surg Suppl , vol.1 , pp. 403-406
    • Farkas, S.1    Herfarth, H.2    Cuba, M.3
  • 45
    • 0013663874 scopus 로고
    • Effect of interleukin-10 in dextran sulfate sodium-induced colitis
    • Abstr.
    • Dieleman LA, de Rover Z, Bloemena E et al. Effect of interleukin-10 in dextran sulfate sodium-induced colitis. Gastroenterology 1995; 110:A895(Abstr.).
    • (1995) Gastroenterology , vol.110
    • Dieleman, L.A.1    De Rover, Z.2    Bloemena, E.3
  • 46
    • 0031707727 scopus 로고    scopus 로고
    • Subtherapeutic corticosteroids potentiate the ability of interleukin-10 to prevent chronic inflammation in rats
    • Herfarth HH, Böcker U, Janardhanam R et al. Subtherapeutic corticosteroids potentiate the ability of interleukin-10 to prevent chronic inflammation in rats. Gastroenterology 1998; 115:1-11.
    • (1998) Gastroenterology , vol.115 , pp. 1-11
    • Herfarth, H.H.1    Böcker, U.2    Janardhanam, R.3
  • 47
    • 4243327373 scopus 로고    scopus 로고
    • In vivo fluorescence microscopy for assessment of leukocyte-endothelial interaction in the left colon in dextran sulphate sodium-induced colitis
    • Abstr.
    • Farkas S, Herfarth H, Steinbauer M et al. In vivo fluorescence microscopy for assessment of leukocyte-endothelial interaction in the left colon in dextran sulphate sodium-induced colitis. Gastroenterology 1998; 114:A973(Abstr.).
    • (1998) Gastroenterology , vol.114
    • Farkas, S.1    Herfarth, H.2    Steinbauer, M.3
  • 48
    • 0032505870 scopus 로고    scopus 로고
    • NF-kappaB activation provides the potential link between inflammation and hyperplasia in the arthritic joint
    • Miagkov AV, Kovalenko DV, Brown CE et al. NF-kappaB activation provides the potential link between inflammation and hyperplasia in the arthritic joint. Proc Natl Acad Sci USA 1998; 95:13859-64.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 13859-13864
    • Miagkov, A.V.1    Kovalenko, D.V.2    Brown, C.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.