Loss of CclA, required for histone 3 lysine 4 methylation, decreases growth but increases secondary metabolite production in Aspergillus fumigatus

PeerJ

Volumn 2013, Issue 1, 2013, Pages

  Palmer, Jonathan M ^a   Bok, Jin Woo ^a   Lee, Seul ^a,c   Dagenais, Taylor R T ^a,d   Andes, David R ^a   Kontoyiannis, Dimitrios P ^b   Keller, Nancy P ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^c University of Texas MD Anderson Cancer Center ^*

^d Madison Area Technical College   (United States)

Author keywords

6 azauracil sensitivity; Aspergillus fumigatus; COMPASS complex; Gliotoxin; Growth and development; Histone methylation; Secondary metabolism

Indexed keywords

AZAURACIL; FUNGAL PROTEIN; GLIOTOXIN; HISTONE H3; LYSINE; PROTEIN CCLA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASPERGILLUS FUMIGATUS; CONTROLLED STUDY; DROSOPHILA; FEMALE; FUNGAL METABOLISM; FUNGAL STRAIN; FUNGUS GROWTH; GENE DELETION; HISTONE METHYLATION; METABOLITE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOGENICITY; POLYMERASE CHAIN REACTION; SOUTHERN BLOTTING; THIN LAYER CHROMATOGRAPHY; WESTERN BLOTTING;

EID: 84877122181     PISSN: None     EISSN: 21678359     Source Type: Journal    
DOI: 10.7717/peerj.4     Document Type: Article

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