VelB/VeA/LaeA complex coordinates light signal with fungal development and secondary metabolism

Science

Volumn 320, Issue 5882, 2008, Pages 1504-1506

  Bayram, Özgür ^a   Krappmann, Sven ^a,d   Ni, Min ^b   Jin, Woo Bok ^b   Helmstaedt, Kerstin ^a,c   Valerius, Oliver ^a   Braus Stromeyer, Susanna ^a   Kwon, Nak Jung ^b   Keller, Nancy P ^b   Yu, Jae Hyuk ^b   Braus, Gerhard H ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

^c Deutsche Forschungsgemeinschaft   (Germany)

^d UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

FUNGAL PROTEIN; PROTEIN LAEA; PROTEIN VEA; PROTEIN VELB; HYBRID PROTEIN; STERIGMATOCYSTIN;

FRUITING; FUNGUS; LIGHT; METABOLISM; SECONDARY METABOLITE; SEXUAL REPRODUCTION; SIGNAL;

ARTICLE; ASPERGILLUS NIDULANS; COMPLEX FORMATION; FRUITING BODY; FUNGAL DEVELOPMENT; FUNGAL METABOLISM; GENE DELETION; LIGHT ABSORPTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SEXUAL DEVELOPMENT; ACTIVE TRANSPORT; BIOSYNTHESIS; CELL NUCLEUS; CHEMISTRY; CYTOPLASM; DARKNESS; FUNGUS SPORE; GENE EXPRESSION REGULATION; GENETIC EPIGENESIS; GENETICS; GROWTH, DEVELOPMENT AND AGING; LIGHT; METABOLISM; PHYSIOLOGY; PROTEIN ANALYSIS; PROTEIN BINDING;

EMERICELLA NIDULANS; FUNGI;

ACTIVE TRANSPORT, CELL NUCLEUS; ASPERGILLUS NIDULANS; CELL NUCLEUS; CYTOPLASM; DARKNESS; EPIGENESIS, GENETIC; FUNGAL PROTEINS; GENE EXPRESSION REGULATION, FUNGAL; LIGHT; PROTEIN BINDING; PROTEIN INTERACTION MAPPING; RECOMBINANT FUSION PROTEINS; SPORES, FUNGAL; STERIGMATOCYSTIN;

EID: 45849147020     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1155888     Document Type: Article

References (29)

1. A. A. Brakhage, FEMS Microbiol. Lett. 148, 1 (1997).
2. J. Hicks, K. Shimizu, N. P. Keller, in The Mycota, vol. 11, F. Kempken, Ed. (Springer, Berlin, 2002), pp. 55-69.
3. T. H. Adams, J. K. Wieser, J.-H. Yu, Microbiol. Mol. Biol. Rev. 62, 35 (1998).
4. J. Purschwitz et al., Curr. Biol. 18, 255 (2008).
5. G. H. Braus, S. Krappmann, S. Eckert, in Molecular Biology of Fungal Development, H. D. Osiewacz, Ed. (Marcel Dekker, New York, 2002), pp. 215-244.
6. A. M. Calvo, R. A. Wilson, J. W. Bok, N. P. Keller, Microbiol. Mol. Biol. Rev. 66, 447 (2002).
7. H. Kim et al., Fungal Genet. Biol. 37, 72 (2002).
8. N. Kato, W. Brooks, A. M. Calvo, Eukaryot. Cell 2, 1178 (2003).
9. S. Busch, S. E. Eckert, S. Krappmann, G. H. Braus, Mol. Microbiol. 49, 717 (2003).
10. S. Krappmann, Ö. Bayram, G. H. Braus, Eukaryot. Cell 4, 1298 (2005).
11. S. Li et al., Mol. Microbiol. 62, 1418 (2006).
12. J. Dreyer, H. Eichhorn, E. Friedlin, H. Kürnsteiner, U. Kück, Appl. Environ. Microbiol. 73, 3412 (2007).
13. S. M. Stinnett, E. A. Espeso, L. Cobeño, L. Araújo- Bazán, A. M. Calvo, Mol. Microbiol. 63, 242 (2007).
14. J. L. Mooney, L. N. Yager, Genes Dev. 4, 1473 (1990).
15. P. Spröte, A. A. Brakhage, Arch. Microbiol. 188, 69 (2007).
16. C. P. Woloshuk et al., Appl. Environ. Microbiol. 60, 2408 (1994).
17. N. P. Keller, G. Turner, J. W. Bennett, Nat. Rev. Microbiol. 3, 937 (2005).
18. J. W. Bok, N. P. Keller, Eukaryot. Cell 3, 527 (2004).
19. J. W. Bok, D. Noordermeer, S. P. Kale, N. P. Keller, Mol. Microbiol. 61, 1636 (2006).
20. E. K. Shwab et al., Eukaryot. Cell 6, 1656 (2007).
21. O. Puig et al., Methods 24, 218 (2001).
22. J. S. Rohila, M. Chen, R. Cerny, M. E. Fromm, Plant J. 38, 172 (2004).
23. S. Busch et al., Proc. Natl. Acad. Sci. U.S.A. 104, 8089 (2007).
24. Materials and methods are available as supporting material on Science Online.
25. M. Ni, J. H. Yu, PLoS One 2, e970 (2007).
26. J. Gyuris, E. Golemis, H. Chertkov, R. Brent, Cell 75, 791 (1993).
27. C. D. Hu, Y. Chinenov, T. K. Kerppola, Mol. Cell 9, 789 (2002).
28. Openlab software 5.0.1, www.improvision.com/.
29. We thank V. Pretz, G. Heinrich, V. Große, and Ö. S. Bayram for technical assistance. This project was supported by the DFG, CMPB, Volkswagen Vorab, and Fonds der Chemischen Industrie to G.H.B; Hatch (WIS04667) and NSF (MCB-0421863) grants to J.-H.Y.; and an NSF grant (MCB-0236393) to N.P.K. The GeneID for velB is 2876142.