Streptomyces clavuligerus HlmI is an intramolecular disulfide-forming dithiol oxidase in holomycin biosynthesis

Biochemistry

Volumn 50, Issue 21, 2011, Pages 4615-4622

  Li, Bo ^a   Walsh, Christopher T ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTI-MICROBIAL ACTIVITY; BIOSYNTHETIC PATHWAY; CO-SUBSTRATE; DISULFIDE BRIDGE; DITHIOL OXIDASE; DITHIOLS; E. COLI; FLAVIN ADENINE DINUCLEOTIDE; LATE STAGE; NATURAL PRODUCTS; OXIDOREDUCTASES; RING STRUCTURES; SMALL MOLECULES; STREPTOMYCES CLAVULIGERUS; THIOREDOXINS; WILD TYPES;

BACTERIA; BIOCHEMISTRY; CATALYSTS; COVALENT BONDS; ENZYMES; ESCHERICHIA COLI; GENES;

BIOSYNTHESIS;

DISULFIDE; DITHIOL DERIVATIVE; FLAVINE ADENINE NUCLEOTIDE; FLAVOPROTEIN; GLIOTOXIN; HOLOMYCIN 1; OXIDOREDUCTASE; OXYGEN; ROMIDEPSIN; THIOREDOXIN; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG SYNTHESIS; ENZYME PURIFICATION; ESCHERICHIA COLI; GENE DELETION; NONHUMAN; OXIDATION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STREPTOMYCES CLAVULIGERUS; WILD TYPE;

BACTERIAL PROTEINS; BASE SEQUENCE; CLONING, MOLECULAR; DISULFIDES; DNA PRIMERS; LACTAMS; MULTIGENE FAMILY; OXIDOREDUCTASES; PHYLOGENY; RECOMBINANT PROTEINS; STREPTOMYCES;

STREPTOMYCES CLAVULIGERUS;

EID: 79958122239     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi200321c     Document Type: Article

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