메뉴 건너뛰기




Volumn 10, Issue , 2015, Pages 3955-3971

Multifaceted applications of bile salts in pharmacy: An emphasis on nanomedicine

Author keywords

Bile salt; Bilosomes; Liposomes; Nanomedicine; Size tunable nanoparticles

Indexed keywords

BILE SALT; BILOSOME; CHOLIC ACID; DRUG CARRIER; LIPOSOME; MACROGOL; NANOCARRIER; NANOPARTICLE; PHOSPHATIDYLCHOLINE; PHOSPHOLIPID; UNCLASSIFIED DRUG; VACCINE; BILE ACID; MICELLE;

EID: 84933545214     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/IJN.S82558     Document Type: Review
Times cited : (77)

References (100)
  • 3
    • 84871166425 scopus 로고    scopus 로고
    • Intestinal probiotics: Interactions with bile salts and reduction of cholesterol
    • Li, G. Intestinal probiotics: interactions with bile salts and reduction of cholesterol. Procedia Environ Sci. 2012;12(Part B):1180–1186.
    • (2012) Procedia Environ Sci , vol.12 , pp. 1180-1186
    • Li, G.1
  • 4
    • 0035815518 scopus 로고    scopus 로고
    • Oral immunisation with peptide and protein antigens by formulation in lipid vesicles incorporating bile salts (bilosomes)
    • Conacher M, Alexander J, Brewer JM. Oral immunisation with peptide and protein antigens by formulation in lipid vesicles incorporating bile salts (bilosomes). Vaccine. 2001;19(20–22): 2965–2974.
    • (2001) Vaccine , vol.19 , Issue.20-22 , pp. 2965-2974
    • Conacher, M.1    Alexander, J.2    Brewer, J.M.3
  • 5
    • 84888857095 scopus 로고    scopus 로고
    • Increased bile acids in enterohepatic circulation by short-term calorie restriction in male mice
    • Fu ZD, Klaassen CD. Increased bile acids in enterohepatic circulation by short-term calorie restriction in male mice. Toxicol Appl Pharmacol. 2013;273(3):680–690.
    • (2013) Toxicol Appl Pharmacol , vol.273 , Issue.3 , pp. 680-690
    • Fu, Z.D.1    Klaassen, C.D.2
  • 6
    • 79956088562 scopus 로고    scopus 로고
    • The bile acid membrane receptor TGR5 as an emerging target in metabolism and infammation
    • Pols TWH, Noriega LG, Nomura M, Auwerx J, Schoonjans K. The bile acid membrane receptor TGR5 as an emerging target in metabolism and infammation. J Hepatol. 2011;54(6):1263–1272.
    • (2011) J Hepatol , vol.54 , Issue.6 , pp. 1263-1272
    • Pols, T.1    Noriega, L.G.2    Nomura, M.3    Auwerx, J.4    Schoonjans, K.5
  • 7
    • 75849126024 scopus 로고    scopus 로고
    • Self-assembly in aqueous bile salt solutions
    • Madenci, D, Egelhaaf SU. Self-assembly in aqueous bile salt solutions. Curr Opin Colloid Interface Sci. 2010;15(1–2):109–115.
    • (2010) Curr Opin Colloid Interface Sci , vol.15 , Issue.1-2 , pp. 109-115
    • Madenci, D.1    Egelhaaf, S.U.2
  • 8
    • 84874118314 scopus 로고    scopus 로고
    • Bile acids: From digestion to cancers
    • Baptissart M, Vega A, Maqdasy S, et al. Bile acids: from digestion to cancers. Biochimie. 2013;95(3):504–517.
    • (2013) Biochimie , vol.95 , Issue.3 , pp. 504-517
    • Baptissart, M.1    Vega, A.2    Maqdasy, S.3
  • 9
    • 80052771111 scopus 로고    scopus 로고
    • Bile acids and colon cancer: Solving the puzzle with nuclear receptors
    • Degirolamo C, Modica S, Palasciano G, Moschetta A. Bile acids and colon cancer: solving the puzzle with nuclear receptors. Trends Mol Med. 2011;17(10):564–572.
    • (2011) Trends Mol Med , vol.17 , Issue.10 , pp. 564-572
    • Degirolamo, C.1    Modica, S.2    Palasciano, G.3    Moschetta, A.4
  • 10
    • 0031687644 scopus 로고    scopus 로고
    • Infuence of absorption enhancers (bile salts) and the preservative (benzalkonium chloride) on mucociliary function and permeation barrier function in rabbit tracheas
    • Morimoto K, Uehara Y, Iwanaga K, et al. Infuence of absorption enhancers (bile salts) and the preservative (benzalkonium chloride) on mucociliary function and permeation barrier function in rabbit tracheas. Eur J Pharm Sci. 1998;6(3):225–230.
    • (1998) Eur J Pharm Sci , vol.6 , Issue.3 , pp. 225-230
    • Morimoto, K.1    Uehara, Y.2    Iwanaga, K.3
  • 12
    • 79960609140 scopus 로고    scopus 로고
    • Improvement of oxaprozin solubility and permeability by the combined use of cyclo-dextrin, chitosan, and bile components
    • Maestrelli F, Cirri M, Mennini N, Zerrouk N, Mura P. Improvement of oxaprozin solubility and permeability by the combined use of cyclo-dextrin, chitosan, and bile components. Eur J Pharm Biopharm. 2011; 78(3):385–393.
    • (2011) Eur J Pharm Biopharm , vol.78 , Issue.3 , pp. 385-393
    • Maestrelli, F.1    Cirri, M.2    Mennini, N.3    Zerrouk, N.4    Mura, P.5
  • 13
    • 70349637456 scopus 로고    scopus 로고
    • A photophysical study on the role of bile salt hydrophobicity in solubilizing amphotericin B aggregates
    • Selvam, S, Andrews ME, Mishra AK. A photophysical study on the role of bile salt hydrophobicity in solubilizing amphotericin B aggregates. J Pharm Sci. 2009;98(11):4153–4160.
    • (2009) J Pharm Sci , vol.98 , Issue.11 , pp. 4153-4160
    • Selvam, S.1    Rews, M.E.2    Mishra, A.K.3
  • 14
    • 84896837155 scopus 로고    scopus 로고
    • Lecithin-based nanostructured gels for skin delivery: An update on state of art and recent applications
    • Elnaggar YS, El-Refaie WM, El-Massik MA, Abdallah OY. Lecithin-based nanostructured gels for skin delivery: an update on state of art and recent applications. J Control Release. 2014;180: 10–24.
    • (2014) J Control Release , vol.180 , pp. 10-24
    • Elnaggar, Y.S.1    El-Refaie, W.M.2    El-Massik, M.A.3    Abdallah, O.Y.4
  • 15
    • 0032484579 scopus 로고    scopus 로고
    • Optimization of systemic nasal drug delivery with pharmaceutical excipients
    • Romeo VD, deMeireles JC, Gries WJ, et al. Optimization of systemic nasal drug delivery with pharmaceutical excipients. Adv Drug Deliv Rev. 1998;29(1–2):117–133.
    • (1998) Adv Drug Deliv Rev , vol.29 , Issue.1-2 , pp. 117-133
    • Romeo, V.D.1    Demeireles, J.C.2    Gries, W.J.3
  • 16
    • 0033844540 scopus 로고    scopus 로고
    • Enhanced permeation of triamcinolone acetonide through the buccal mucosa
    • Shin S-C, Kim J-Y. Enhanced permeation of triamcinolone acetonide through the buccal mucosa. Eur J Pharm Biopharm. 2000;50(2): 217–220.
    • (2000) Eur J Pharm Biopharm , vol.50 , Issue.2 , pp. 217-220
    • Shin, S.-C.1    Kim, J.-Y.2
  • 17
    • 8444221576 scopus 로고    scopus 로고
    • Development of lidocaine gels for enhanced local anesthetic action
    • Shin S-C, Cho C-W, Yang K-H. Development of lidocaine gels for enhanced local anesthetic action. Int J Pharm. 2004;287(1–2): 73–78.
    • (2004) Int J Pharm , vol.287 , Issue.1-2 , pp. 73-78
    • Shin, S.-C.1    Cho, C.-W.2    Yang, K.-H.3
  • 18
    • 34250645007 scopus 로고    scopus 로고
    • Low molecular mass cationic gelators derived from deoxycholic acid: Remarkable gelation of aqueous solvents
    • Bhat S, Maitra U. Low molecular mass cationic gelators derived from deoxycholic acid: remarkable gelation of aqueous solvents. Tetrahedron. 2007;63(31):7309–7320.
    • (2007) Tetrahedron , vol.63 , Issue.31 , pp. 7309-7320
    • Bhat, S.1    Maitra, U.2
  • 19
    • 85017733937 scopus 로고    scopus 로고
    • Novel self-assembled, gel-core hyaluosomes for non-invasive management of osteoarthritis: In-vitro optimization, ex-vivo and in-vivo permeation. Pharm Res
    • El-Refaieb WM, Elnagger YS, El-Massikb MA, Abdallaha OY. Novel self-assembled, gel-core hyaluosomes for non-invasive management of osteoarthritis: in-vitro optimization, ex-vivo and in-vivo permeation. Pharm Res. Epub March 17, 2015.
    • (2015) Epub March , pp. 17
    • El-Refaieb, W.M.1    Elnagger, Y.S.2    El-Massikb, M.A.3    Abdallaha, O.Y.4
  • 20
    • 84861302273 scopus 로고    scopus 로고
    • Fabrication, appraisal, and transdermal permeation of sildenafl citrate-loaded nanostructured lipid carriers versus solid lipid nanoparticles
    • Elnaggar, YS, El-Massik MA, Abdallah OY. Fabrication, appraisal, and transdermal permeation of sildenafl citrate-loaded nanostructured lipid carriers versus solid lipid nanoparticles. Int J Nanomedicine. 2011; 6:3195–3205.
    • (2011) Int J Nanomedicine , vol.6 , pp. 3195-3205
    • Elnaggar, Y.S.1    El-Massik, M.A.2    Abdallah, O.Y.3
  • 21
    • 69749105594 scopus 로고    scopus 로고
    • Self-nanoemulsifying drug delivery systems of tamoxifen citrate: Design and optimization
    • Elnaggar YS, El-Massik MA, Abdallah OY. Self-nanoemulsifying drug delivery systems of tamoxifen citrate: design and optimization. Int J Pharm. 2009;380(1–2):133–141.
    • (2009) Int J Pharm , vol.380 , Issue.1-2 , pp. 133-141
    • Elnaggar, Y.S.1    El-Massik, M.A.2    Abdallah, O.Y.3
  • 22
    • 84870315186 scopus 로고    scopus 로고
    • Nanoemulsion liquid preconcentrates for raloxifene hydrochloride: Optimization and in vivo appraisal
    • Elsheikh MA, Elnaggar YS, Gohar EY, Abdallah OY. Nanoemulsion liquid preconcentrates for raloxifene hydrochloride: optimization and in vivo appraisal. Int J Nanomedicine. 2012;7:3787–3802.
    • (2012) Int J Nanomedicine , vol.7 , pp. 3787-3802
    • Elsheikh, M.A.1    Elnaggar, Y.S.2    Gohar, E.Y.3    Abdallah, O.Y.4
  • 23
    • 84879977264 scopus 로고    scopus 로고
    • Lyophilized phytosomal nano-carriers as platforms for enhanced diosmin delivery: Optimization and ex vivo permeation
    • Freag MS, Elnaggar YS, Abdallah OY. Lyophilized phytosomal nano-carriers as platforms for enhanced diosmin delivery: optimization and ex vivo permeation. Int J Nanomedicine. 2013;8:2385–2397.
    • (2013) Int J Nanomedicine , vol.8 , pp. 2385-2397
    • Freag, M.S.1    Elnaggar, Y.S.2    Abdallah, O.Y.3
  • 24
    • 84884160175 scopus 로고    scopus 로고
    • Development of novel polymer-stabilized diosmin nanosuspensions: In vitro appraisal and ex vivo permeation
    • Freag MS, Elnaggar YS, Abdallah OY. Development of novel polymer-stabilized diosmin nanosuspensions: in vitro appraisal and ex vivo permeation. Int J Pharm. 2013;454(1):462–471.
    • (2013) Int J Pharm , vol.454 , Issue.1 , pp. 462-471
    • Freag, M.S.1    Elnaggar, Y.S.2    Abdallah, O.Y.3
  • 25
    • 79960803950 scopus 로고    scopus 로고
    • Sildenafl citrate nano-emulsion vs self-nanoemulsifying delivery systems: Rational development and transdermal permeation
    • Elnaggar YS, El-Massik MA, Abdallah O Y. Sildenafl citrate nano-emulsion vs self-nanoemulsifying delivery systems: rational development and transdermal permeation. Int J Nanotechnol. 2011;8(8): 749–763.
    • (2011) Int J Nanotechnol , vol.8 , Issue.8 , pp. 749-763
    • Elnaggar, Y.S.1    El-Massik, M.A.2    Abdallah, O.Y.3
  • 26
    • 84929091401 scopus 로고    scopus 로고
    • Development of dual toxoid-loaded layersomes for complete immunostimulatory response following peroral administration
    • Harde H, Siddhapura K, Agrawal AK, Jain S. Development of dual toxoid-loaded layersomes for complete immunostimulatory response following peroral administration. Nanomedicine (Lond). 2015;10(7): 1077–1091.
    • (2015) Nanomedicine (Lond) , vol.10 , Issue.7 , pp. 1077-1091
    • Harde, H.1    Siddhapura, K.2    Agrawal, A.K.3    Jain, S.4
  • 27
    • 84969418052 scopus 로고    scopus 로고
    • Enhanced permeability across Caco-2 cell monolayers by specific man-nosylating ligand of buserelin acetate proliposomes
    • Yingsukwattana K, Puttipipatkhachorn S, Ruktanonchai U, Sarisuta N. Enhanced permeability across Caco-2 cell monolayers by specific man-nosylating ligand of buserelin acetate proliposomes. J Liposome Res. Epub 2015;6:1–11.
    • (2015) J Liposome Res. Epub , vol.6 , pp. 1-11
    • Yingsukwattana, K.1    Puttipipatkhachorn, S.2    Ruktanonchai, U.3    Sarisuta, N.4
  • 28
    • 79151473262 scopus 로고    scopus 로고
    • Stability of liposomes containing bio-enhancers and tetraether lipids in simulated gastrointestinal fuids
    • Parmentier J, Becker MM, Heintz U, Fricker G. Stability of liposomes containing bio-enhancers and tetraether lipids in simulated gastrointestinal fuids. Int J Pharm. 2011;405(1–2):210–217.
    • (2011) Int J Pharm , vol.405 , Issue.1-2 , pp. 210-217
    • Parmentier, J.1    Becker, M.M.2    Heintz, U.3    Fricker, G.4
  • 29
    • 84895068018 scopus 로고    scopus 로고
    • Improved stability and immunological potential of tetanus toxoid containing surface engineered bilosomes following oral administration
    • Jain S, Harde H, Indulkar A, Agrawal AK. Improved stability and immunological potential of tetanus toxoid containing surface engineered bilosomes following oral administration. Nanomedicine. 2014; 10(2):431–440.
    • (2014) Nanomedicine , vol.10 , Issue.2 , pp. 431-440
    • Jain, S.1    Harde, H.2    Indulkar, A.3    Agrawal, A.K.4
  • 30
    • 0032948154 scopus 로고    scopus 로고
    • Improved stability of highly fuori-nated phospholipid-based vesicles in the presence of bile salts
    • Gadras C, Santaella C, Vierling P. Improved stability of highly fuori-nated phospholipid-based vesicles in the presence of bile salts. J Control Release. 1999;57(1):29–34.
    • (1999) J Control Release , vol.57 , Issue.1 , pp. 29-34
    • Gadras, C.1    Santaella, C.2    Vierling, P.3
  • 31
    • 84872763300 scopus 로고    scopus 로고
    • Integrity and stability of oral liposomes containing bile salts studied in simulated and ex vivo gastrointestinal media
    • Hu S, Niu M, Hu F, et al. Integrity and stability of oral liposomes containing bile salts studied in simulated and ex vivo gastrointestinal media. Int J Pharm. 2013;441(1–2):693–700.
    • (2013) Int J Pharm , vol.441 , Issue.1-2 , pp. 693-700
    • Hu, S.1    Niu, M.2    Hu, F.3
  • 32
    • 59649096972 scopus 로고    scopus 로고
    • Solubilisation of dipalmitoylphosphatidylcholine bilay-ers by sodium taurocholate: A model to study the stability of liposomes in the gastrointestinal tract and their mechanism of interaction with a model bile salt
    • Andrieux K, Forte L, Lesieur S, Paternostre M, Ollivon M, Grabielle-Madelmont C. Solubilisation of dipalmitoylphosphatidylcholine bilay-ers by sodium taurocholate: a model to study the stability of liposomes in the gastrointestinal tract and their mechanism of interaction with a model bile salt. Eur J Pharm Biopharm. 2009;71(2):346–355.
    • (2009) Eur J Pharm Biopharm , vol.71 , Issue.2 , pp. 346-355
    • Andrieux, K.1    Forte, L.2    Lesieur, S.3    Paternostre, M.4    Ollivon, M.5    Grabielle-Madelmont, C.6
  • 33
    • 21344455951 scopus 로고    scopus 로고
    • Cholesterol–bile salt vesicles as potential delivery vehicles for drug and vaccine delivery
    • Martin C, Thongborisute J, Takeuchi H, Yamamoto H, Kawashima Y, Alpar HO. Cholesterol–bile salt vesicles as potential delivery vehicles for drug and vaccine delivery. Int J Pharm. 2005;298(2):339–343.
    • (2005) Int J Pharm , vol.298 , Issue.2 , pp. 339-343
    • Martin, C.1    Thongborisute, J.2    Takeuchi, H.3    Yamamoto, H.4    Kawashima, Y.5    Alpar, H.O.6
  • 34
    • 84873503828 scopus 로고    scopus 로고
    • Recombinant baculovirus associated with bilosomes as an oral vaccine candidate against HEV71 infection in mice
    • Premanand B, Prabakaran M, Kiener TK, Kwang J. Recombinant baculovirus associated with bilosomes as an oral vaccine candidate against HEV71 infection in mice. PLoS One. 2013;8(2):e55536.
    • (2013) Plos One , vol.8 , Issue.2
    • Premanand, B.1    Prabakaran, M.2    Kiener, T.K.3    Kwang, J.4
  • 35
    • 0035888375 scopus 로고    scopus 로고
    • Bilosomes: The answer to oral vaccine delivery?
    • Senior K. Bilosomes: the answer to oral vaccine delivery? Drug Discov Today. 2001;6(20):1031–1032.
    • (2001) Drug Discov Today , vol.6 , Issue.20 , pp. 1031-1032
    • Senior, K.1
  • 36
    • 72449211710 scopus 로고    scopus 로고
    • M-cell targeted delivery of recombinant hepatitis B surface antigen using cholera toxin B subunit conjugated bilosomes
    • Shukla A, Katare OP, Singh B, Vyas SP. M-cell targeted delivery of recombinant hepatitis B surface antigen using cholera toxin B subunit conjugated bilosomes. Int J Pharm. 2010;385(1–2):47–52.
    • (2010) Int J Pharm , vol.385 , Issue.1-2 , pp. 47-52
    • Shukla, A.1    Katare, O.P.2    Singh, B.3    Vyas, S.P.4
  • 37
    • 53549127573 scopus 로고    scopus 로고
    • Oral immunization against hepatitis B using bile salt stabilized vesicles (bilosomes)
    • Shukla A, Khatri K, Gupta PN, Goyal AK, Mehta A, Vyas SP. Oral immunization against hepatitis B using bile salt stabilized vesicles (bilosomes). J Pharm Pharm Sci. 2008;11(1):59–66.
    • (2008) J Pharm Pharm Sci , vol.11 , Issue.1 , pp. 59-66
    • Shukla, A.1    Khatri, K.2    Gupta, P.N.3    Goyal, A.K.4    Mehta, A.5    Vyas, S.P.6
  • 38
    • 80052238985 scopus 로고    scopus 로고
    • Significant systemic and mucosal immune response induced on oral delivery of diphtheria toxoid using nano-bilosomes
    • Shukla A, Singh B, Katare OP. Significant systemic and mucosal immune response induced on oral delivery of diphtheria toxoid using nano-bilosomes. Br J Pharmacol. 2011;164(2b):820–827.
    • (2011) Br J Pharmacol , vol.164 , Issue.2 b , pp. 820-827
    • Shukla, A.1    Singh, B.2    Katare, O.P.3
  • 40
    • 84888599853 scopus 로고    scopus 로고
    • Enhanced oral absorption of insulin-loaded liposomes containing bile salts: A mechanistic study
    • Niu M, Tan Y, Guan P, et al. Enhanced oral absorption of insulin-loaded liposomes containing bile salts: a mechanistic study. Int J Pharm. 2014; 460(1–2):119–130.
    • (2014) Int J Pharm , vol.460 , Issue.1-2 , pp. 119-130
    • Niu, M.1    Tan, Y.2    Guan, P.3
  • 41
    • 67349097388 scopus 로고    scopus 로고
    • Enhanced bioavailability of the poorly water-soluble drug fenofbrate by using liposomes containing a bile salt
    • Chen Y, Lu Y, Chen J, et al. Enhanced bioavailability of the poorly water-soluble drug fenofbrate by using liposomes containing a bile salt. Int J Pharm. 2009;376(1–2):153–160.
    • (2009) Int J Pharm , vol.376 , Issue.1-2 , pp. 153-160
    • Chen, Y.1    Lu, Y.2    Chen, J.3
  • 42
    • 84865698988 scopus 로고    scopus 로고
    • Imaging of the GI tract by QDs loaded heparin-deoxycholic acid (DOCA) nanoparticles
    • Khatun Z, Nurunnabi M, Cho KJ, Lee YK. Imaging of the GI tract by QDs loaded heparin-deoxycholic acid (DOCA) nanoparticles. Carbo-hydr Polym. 2012;90(4):1461–1468.
    • (2012) Carbo-Hydr Polym , vol.90 , Issue.4 , pp. 1461-1468
    • Khatun, Z.1    Nurunnabi, M.2    Cho, K.J.3    Lee, Y.K.4
  • 43
    • 77952742675 scopus 로고    scopus 로고
    • Deoxycholic acid modified-carboxymethyl curdlan conjugate as a novel carrier of epirubicin: In vitro and in vivo studies
    • Gao F, Li L, Zhang H, et al. Deoxycholic acid modified-carboxymethyl curdlan conjugate as a novel carrier of epirubicin: in vitro and in vivo studies. Int J Pharm. 2010;392(1–2):254–260.
    • (2010) Int J Pharm , vol.392 , Issue.1-2 , pp. 254-260
    • Gao, F.1    Li, L.2    Zhang, H.3
  • 44
    • 84884154027 scopus 로고    scopus 로고
    • Bile salts and their importance for drug absorption
    • Holm R, Mullertz A, Mu H. Bile salts and their importance for drug absorption. Int J Pharm. 2013;453(1):44–55.
    • (2013) Int J Pharm , vol.453 , Issue.1 , pp. 44-55
    • Holm, R.1    Mullertz, A.2    Mu, H.3
  • 46
    • 33745976753 scopus 로고    scopus 로고
    • The novel formulation design of self-emulsifying drug delivery systems (SEDDS) type O/W microemulsion I: Enhancing effects on oral bioavailability of poorly water soluble compounds in rats and beagle dogs
    • Araya H, Nagao S, Tomita M, Hayashi M. The novel formulation design of self-emulsifying drug delivery systems (SEDDS) type O/W microemulsion I: enhancing effects on oral bioavailability of poorly water soluble compounds in rats and beagle dogs. Drug Metab Phar-macokinet. 2005;20(4):244–256.
    • (2005) Drug Metab Phar-Macokinet , vol.20 , Issue.4 , pp. 244-256
    • Araya, H.1    Nagao, S.2    Tomita, M.3    Hayashi, M.4
  • 47
    • 0033039631 scopus 로고    scopus 로고
    • Enhanced absorption of cyclosporin A by complexation with dimethyl-beta-cyclodextrin in bile duct-cannulated and -noncannulated rats
    • Miyake K, Arima H, Irie T, Hirayama F, Uekama K. Enhanced absorption of cyclosporin A by complexation with dimethyl-beta-cyclodextrin in bile duct-cannulated and -noncannulated rats. Biol Pharm Bull. 1999; 22(1):66–72.
    • (1999) Biol Pharm Bull , vol.22 , Issue.1 , pp. 66-72
    • Miyake, K.1    Arima, H.2    Irie, T.3    Hirayama, F.4    Uekama, K.5
  • 48
    • 57349157027 scopus 로고    scopus 로고
    • The infuence of bile acids on the oral bioavailability of vitamin K encapsulated in polymeric micelles
    • van Hasselt PM, Janssens GE, Slot TK, et al. The infuence of bile acids on the oral bioavailability of vitamin K encapsulated in polymeric micelles. J Control Release. 2009;133(2):161–168.
    • (2009) J Control Release , vol.133 , Issue.2 , pp. 161-168
    • Van Hasselt, P.M.1    Janssens, G.E.2    Slot, T.K.3
  • 49
    • 0032706009 scopus 로고    scopus 로고
    • Enhanced absorption of oral furosemide by bile juice in rats
    • Kim EJ, Han KS, Lee MG. Enhanced absorption of oral furosemide by bile juice in rats. Res Commun Mol Pathol Pharmacol. 1999;104(1): 107–110.
    • (1999) Res Commun Mol Pathol Pharmacol , vol.104 , Issue.1 , pp. 107-110
    • Kim, E.J.1    Han, K.S.2    Lee, M.G.3
  • 50
    • 84884202738 scopus 로고    scopus 로고
    • Bile salts enhance the intestinal absorption of lipophilic drug loaded lipid nanocarriers: Mechanism and effect in rats
    • Zhang Z, Gao F, Jiang S, et al. Bile salts enhance the intestinal absorption of lipophilic drug loaded lipid nanocarriers: mechanism and effect in rats. Int J Pharm. 2013;452(1–2):374–381.
    • (2013) Int J Pharm , vol.452 , Issue.1-2 , pp. 374-381
    • Zhang, Z.1    Gao, F.2    Jiang, S.3
  • 51
    • 79958830034 scopus 로고    scopus 로고
    • Bile acid alkylamide derivatives as low molecular weight organogelators: Systematic gelation studies and qualitative structural analysis of the systems
    • Lofman M, Koivukorpi J, Noponen V, Salo H, Sievänen E. Bile acid alkylamide derivatives as low molecular weight organogelators: systematic gelation studies and qualitative structural analysis of the systems. J Colloid Interface Sci. 2011;360(2):633–644.
    • (2011) J Colloid Interface Sci , vol.360 , Issue.2 , pp. 633-644
    • Lofman, M.1    Koivukorpi, J.2    Noponen, V.3    Salo, H.4    Sievänen, E.5
  • 52
    • 84878917518 scopus 로고    scopus 로고
    • Study on interaction of bile salts with curcumin and curcumin embedded in dipalmitoyl-sn-glycero-3-phosphocholine liposome
    • Patra D, Ahmadieh D, Aridi R. Study on interaction of bile salts with curcumin and curcumin embedded in dipalmitoyl-sn-glycero-3-phosphocholine liposome. Colloids Surf B Biointerfaces. 2013;110: 296–304.
    • (2013) Colloids Surf B Biointerfaces , vol.110 , pp. 296-304
    • Patra, D.1    Ahmadieh, D.2    Aridi, R.3
  • 53
    • 77649183728 scopus 로고    scopus 로고
    • Mixed micelle formation with phos-phatidylcholines: The infuence of surfactants with different molecule structures
    • Rupp C, Steckel H, Muller B W. Mixed micelle formation with phos-phatidylcholines: the infuence of surfactants with different molecule structures. Int J Pharm. 2010;387(1–2):120–128.
    • (2010) Int J Pharm , vol.387 , Issue.1-2 , pp. 120-128
    • Rupp, C.1    Steckel, H.2    Muller, B.W.3
  • 54
    • 33750115275 scopus 로고    scopus 로고
    • Biodegradable polymers based on bile acids and potential biomedical applications
    • Gautrot JE, Zhu XX. Biodegradable polymers based on bile acids and potential biomedical applications. J Biomater Sci. 2006;17(10): 1123–1139.
    • (2006) J Biomater Sci , vol.17 , Issue.10 , pp. 1123-1139
    • Gautrot, J.E.1    Zhu, X.X.2
  • 55
    • 84893751465 scopus 로고    scopus 로고
    • Physicochemical characterization of amphiphilic nanoparticles based on the novel starch-deoxycholic acid conjugates and self-aggregates
    • Yang J, Gao C, Lü S, Zhang X, Yu C, Liu M. Physicochemical characterization of amphiphilic nanoparticles based on the novel starch-deoxycholic acid conjugates and self-aggregates. Carbohydr Polym. 2014;102:838–845.
    • (2014) Carbohydr Polym , vol.102 , pp. 838-845
    • Yang, J.1    Gao, C.2    Lü, S.3    Zhang, X.4    Yu, C.5    Liu, M.6
  • 56
    • 84887264700 scopus 로고    scopus 로고
    • Paclitaxel-loaded nanoparticles of star-shaped cholic acid-core PLA-TPGS copolymer for breast cancer treatment
    • Tang X, Cai S, Zhang R, et al. Paclitaxel-loaded nanoparticles of star-shaped cholic acid-core PLA-TPGS copolymer for breast cancer treatment. Nanoscale Res Lett. 2013;8(1):420.
    • (2013) Nanoscale Res Lett , vol.8 , Issue.1 , pp. 420
    • Tang, X.1    Cai, S.2    Zhang, R.3
  • 57
    • 84878614148 scopus 로고    scopus 로고
    • Cholic acid-function-alized nanoparticles of star-shaped PLGA-vitamin E TPGS copolymer for docetaxel delivery to cervical cancer
    • Zeng X, Tao W, Mei L, Huang L, Tan C, Feng SS. Cholic acid-function-alized nanoparticles of star-shaped PLGA-vitamin E TPGS copolymer for docetaxel delivery to cervical cancer. Biomaterials. 2013;34(25): 6058–6067.
    • (2013) Biomaterials , vol.34 , Issue.25 , pp. 6058-6067
    • Zeng, X.1    Tao, W.2    Mei, L.3    Huang, L.4    Tan, C.5    Feng, S.S.6
  • 58
    • 77953286839 scopus 로고    scopus 로고
    • A novel size-tunable nanocarrier system for targeted anticancer drug delivery
    • Li Y, Xiao K, Luo J, Lee J, Pan S, Lam KS. A novel size-tunable nanocarrier system for targeted anticancer drug delivery. J Control Release. 2010;144(3):314–323.
    • (2010) J Control Release , vol.144 , Issue.3 , pp. 314-323
    • Li, Y.1    Xiao, K.2    Luo, J.3    Lee, J.4    Pan, S.5    Lam, K.S.6
  • 59
    • 37048998748 scopus 로고    scopus 로고
    • Preparation and physicochemi-cal characteristics of self-assembled nanoparticles of deoxycholic acid modified-carboxymethyl curdlan conjugates
    • Gao F-P, Zhang, HZ, Liu, LR, et al. Preparation and physicochemi-cal characteristics of self-assembled nanoparticles of deoxycholic acid modified-carboxymethyl curdlan conjugates. Carbohydr Polym. 2008;71(4):606–613.
    • (2008) Carbohydr Polym , vol.71 , Issue.4 , pp. 606-613
    • Gao, F.-P.1    Zhang, H.Z.2    Liu, L.R.3
  • 60
    • 77249104877 scopus 로고    scopus 로고
    • Effects of particle size and surface charge on cellular uptake and biodistribution of polymeric nanoparticles
    • He C, Hu Y, Yin L, Tang C, Yin C. Effects of particle size and surface charge on cellular uptake and biodistribution of polymeric nanoparticles. Biomaterials. 2010;31(13):3657–3666.
    • (2010) Biomaterials , vol.31 , Issue.13 , pp. 3657-3666
    • He, C.1    Hu, Y.2    Yin, L.3    Tang, C.4    Yin, C.5
  • 61
    • 69249202279 scopus 로고    scopus 로고
    • A self-assembling nanoparticle for paclitaxel delivery in ovarian cancer
    • Xiao K, Luo J, Fowler WL, et al. A self-assembling nanoparticle for paclitaxel delivery in ovarian cancer. Biomaterials. 2009;30(30): 6006–6016.
    • (2009) Biomaterials , vol.30 , Issue.30 , pp. 6006-6016
    • Xiao, K.1    Luo, J.2    Fowler, W.L.3
  • 62
    • 77954875228 scopus 로고    scopus 로고
    • Well-defined, size-tunable, multifunctional micelles for efficient paclitaxel delivery for cancer treatment
    • Luo J, Xiao K, Li Y, et al. Well-defined, size-tunable, multifunctional micelles for efficient paclitaxel delivery for cancer treatment. Bioconjug Chem. 2010;21(7):1216–1224.
    • (2010) Bioconjug Chem , vol.21 , Issue.7 , pp. 1216-1224
    • Luo, J.1    Xiao, K.2    Li, Y.3
  • 63
    • 51049090204 scopus 로고    scopus 로고
    • Nanoparticle therapeutics: An emerging treatment modality for cancer
    • Davis ME, Chen ZG, Shin DM. Nanoparticle therapeutics: an emerging treatment modality for cancer. Nat Rev Drug Discov. 2008;7(9): 771–782.
    • (2008) Nat Rev Drug Discov , vol.7 , Issue.9 , pp. 771-782
    • Davis, M.E.1    Chen, Z.G.2    Shin, D.M.3
  • 64
    • 33748797672 scopus 로고    scopus 로고
    • Macrophage uptake of core-shell nanoparticles surface modified with poly(ethylene glycol)
    • Zahr AS, Davis CA, Pishko MV. Macrophage uptake of core-shell nanoparticles surface modified with poly(ethylene glycol). Langmuir. 2006;22(19):8178–8185.
    • (2006) Langmuir , vol.22 , Issue.19 , pp. 8178-8185
    • Zahr, A.S.1    Davis, C.A.2    Pishko, M.V.3
  • 65
    • 79952008706 scopus 로고    scopus 로고
    • The effect of surface charge on in vivo biodistribution of PEG-oligocholic acid based micellar nanoparticles
    • Xiao K, Li Y, Luo J, et al. The effect of surface charge on in vivo biodistribution of PEG-oligocholic acid based micellar nanoparticles. Biomaterials. 2011;32(13):3435–3446.
    • (2011) Biomaterials , vol.32 , Issue.13 , pp. 3435-3446
    • Xiao, K.1    Li, Y.2    Luo, J.3
  • 66
    • 84888419295 scopus 로고    scopus 로고
    • Infuence of nanoparticle shape, size, and surface functionalization on cellular uptake
    • Ma N, Ma C, Li C, et al. Infuence of nanoparticle shape, size, and surface functionalization on cellular uptake. J Nanosci Nanotechnol. 2013;13(10): 6485–6498.
    • (2013) J Nanosci Nanotechnol , vol.13 , Issue.10 , pp. 6485-6498
    • Ma, N.1    Ma, C.2    Li, C.3
  • 69
    • 84866617174 scopus 로고    scopus 로고
    • Interactions of phenothiazine drugs with bile salts: Micellization and binding studies
    • Mahajan S, Mahajan RK. Interactions of phenothiazine drugs with bile salts: micellization and binding studies. J Colloid Interface Sci. 2012;387(1):194–204.
    • (2012) J Colloid Interface Sci , vol.387 , Issue.1 , pp. 194-204
    • Mahajan, S.1    Mahajan, R.K.2
  • 70
    • 84871884902 scopus 로고    scopus 로고
    • Lecithin in mixed micelles attenuates the cytotoxicity of bile salts in Caco-2 cells
    • Tan Y, Qi J, Lu Y, Hu F, Yin Z, Wu W. Lecithin in mixed micelles attenuates the cytotoxicity of bile salts in Caco-2 cells. Toxicol In Vitro. 2013;27(2): 714–720.
    • (2013) Toxicol in Vitro , vol.27 , Issue.2 , pp. 714-720
    • Tan, Y.1    Qi, J.2    Lu, Y.3    Hu, F.4    Yin, Z.5    Wu, W.6
  • 72
    • 77953283333 scopus 로고    scopus 로고
    • Enhancement of oral bioavailability of the poorly water-soluble drug silybin by sodium cholate/phospholipid-mixed micelles
    • Yu JN, Zhu Y, Wang L, et al. Enhancement of oral bioavailability of the poorly water-soluble drug silybin by sodium cholate/phospholipid-mixed micelles. Acta Pharmacol Sin. 2010;31(6):759–764.
    • (2010) Acta Pharmacol Sin , vol.31 , Issue.6 , pp. 759-764
    • Yu, J.N.1    Zhu, Y.2    Wang, L.3
  • 73
    • 0001577992 scopus 로고    scopus 로고
    • From mixed micelles to liposomes: Critical steps during detergent removal by membrane dialysis
    • Wacker M, Schubert R. From mixed micelles to liposomes: critical steps during detergent removal by membrane dialysis. Int J Pharm. 1998;162(1–2):171–175.
    • (1998) Int J Pharm , vol.162 , Issue.1-2 , pp. 171-175
    • Wacker, M.1    Schubert, R.2
  • 74
    • 84862824387 scopus 로고    scopus 로고
    • Hypoglycemic activity and oral bio-availability of insulin-loaded liposomes containing bile salts in rats: The effect of cholate type, particle size and administered dose
    • Niu M, Lu Y, Hovgaard L, et al. Hypoglycemic activity and oral bio-availability of insulin-loaded liposomes containing bile salts in rats: the effect of cholate type, particle size and administered dose. Eur J Pharm Biopharm. 2012;81(2):265–272.
    • (2012) Eur J Pharm Biopharm , vol.81 , Issue.2 , pp. 265-272
    • Niu, M.1    Lu, Y.2    Hovgaard, L.3
  • 75
    • 84898442761 scopus 로고    scopus 로고
    • Oral mucosal immunization using glucomannosylated bilosomes
    • Jain S, Indulkar A, Harde H, Agrawal AK. Oral mucosal immunization using glucomannosylated bilosomes. J Biomed Nanotechnol. 2014;10(6): 932–947.
    • (2014) J Biomed Nanotechnol , vol.10 , Issue.6 , pp. 932-947
    • Jain, S.1    Indulkar, A.2    Harde, H.3    Agrawal, A.K.4
  • 76
    • 84925341684 scopus 로고    scopus 로고
    • Bile salts-containing vesicles: Promising pharmaceutical carriers for oral delivery of poorly water-soluble drugs and peptide/protein-based therapeutics or vaccines
    • Aburahma MH. Bile salts-containing vesicles: promising pharmaceutical carriers for oral delivery of poorly water-soluble drugs and peptide/protein-based therapeutics or vaccines. Drug Deliv. 2014: 1–21.
    • (2014) Drug Deliv , pp. 1-21
    • Aburahma, M.H.1
  • 77
    • 79961128909 scopus 로고    scopus 로고
    • Effects of bile salts on propranolol distribution into liposomes studied by capillary electrophoresis
    • Yang L, Tucker IG, Ostergaard J. Effects of bile salts on propranolol distribution into liposomes studied by capillary electrophoresis. J Pharm Biomed Anal. 2011;56(3):553–559.
    • (2011) J Pharm Biomed Anal , vol.56 , Issue.3 , pp. 553-559
    • Yang, L.1    Tucker, I.G.2    Ostergaard, J.3
  • 78
    • 80155182416 scopus 로고    scopus 로고
    • Enhanced oral bioavailability of cyclo-sporine A by liposomes containing a bile salt
    • Guan P, Lu Y, Qi J, et al. Enhanced oral bioavailability of cyclo-sporine A by liposomes containing a bile salt. Int J Nanomedicine. 2011;6:965–974.
    • (2011) Int J Nanomedicine , vol.6 , pp. 965-974
    • Guan, P.1    Lu, Y.2    Qi, J.3
  • 79
    • 84907200641 scopus 로고    scopus 로고
    • Rationale employment of cell culture versus conventional techniques in pharmaceutical appraisal of nanocarriers
    • Elsheikh MA, Elnaggar YS, Abdallah OY. Rationale employment of cell culture versus conventional techniques in pharmaceutical appraisal of nanocarriers. J Control Release. 2014;194:92–102.
    • (2014) J Control Release , vol.194 , pp. 92-102
    • Elsheikh, M.A.1    Elnaggar, Y.S.2    Abdallah, O.Y.3
  • 80
    • 84887381890 scopus 로고    scopus 로고
    • Ion pairing with bile salts modulates intestinal permeability and contributes to food-drug interaction of BCS class III compound trospium chloride
    • Heinen CA, Reuss S, Amidon GL, Langguth P. Ion pairing with bile salts modulates intestinal permeability and contributes to food-drug interaction of BCS class III compound trospium chloride. Mol Pharm. 2013;10(11): 3989–3996.
    • (2013) Mol Pharm , vol.10 , Issue.11 , pp. 3989-3996
    • Heinen, C.A.1    Reuss, S.2    Amidon, G.L.3    Langguth, P.4
  • 81
    • 23944494896 scopus 로고    scopus 로고
    • Enhanced intestinal absorption of salmon calcitonin (sCT) from proliposomes containing bile salts
    • Song K-H, Chung S-J, Shim C-K. Enhanced intestinal absorption of salmon calcitonin (sCT) from proliposomes containing bile salts. J Control Release. 2005;106(3):298–308.
    • (2005) J Control Release , vol.106 , Issue.3 , pp. 298-308
    • Song, K.-H.1    Chung, S.-J.2    Shim, C.-K.3
  • 82
    • 0033991088 scopus 로고    scopus 로고
    • Stability of SUV liposomes in the presence of cholate salts and pancreatic lipases: Effect of lipid composition
    • Kokkona M, Kallinteri P, Fatouros D, Antimisiaris SG. Stability of SUV liposomes in the presence of cholate salts and pancreatic lipases: effect of lipid composition. Eur J Pharm Sci. 2000;9(3):245–252.
    • (2000) Eur J Pharm Sci , vol.9 , Issue.3 , pp. 245-252
    • Kokkona, M.1    Kallinteri, P.2    Fatouros, D.3    Antimisiaris, S.G.4
  • 83
    • 84888287958 scopus 로고    scopus 로고
    • Structural transition in aqueous lipid/bile salt [DPPC/ NaDC] supramolecular aggregates: SANS and DLS study
    • Kiselev MA, Janich M, Hildebrand A, Strunz P, Neubert RHH, Lombardo D. Structural transition in aqueous lipid/bile salt [DPPC/ NaDC] supramolecular aggregates: SANS and DLS study. Chem Phys. 2013;424:93–99.
    • (2013) Chem Phys , vol.424 , pp. 93-99
    • Kiselev, M.A.1    Janich, M.2    Hildebrand, A.3    Strunz, P.4    Neubert, R.5    Lombardo, D.6
  • 84
    • 84862833264 scopus 로고    scopus 로고
    • Liposomes containing glycocholate as potential oral insulin delivery systems: Preparation, in vitro characterization, and improved protection against enzymatic degradation
    • Niu M, Lu Y, Hovgaard L, Wu W. Liposomes containing glycocholate as potential oral insulin delivery systems: preparation, in vitro characterization, and improved protection against enzymatic degradation. Int J Nanomedicine. 2011;6:1155–1166.
    • (2011) Int J Nanomedicine , vol.6 , pp. 1155-1166
    • Niu, M.1    Lu, Y.2    Hovgaard, L.3    Wu, W.4
  • 86
    • 84864711867 scopus 로고    scopus 로고
    • Improved in vitro and in vivo collagen biosynthesis by asiaticoside-loaded ultradeformable vesicles
    • Paolino D, Cosco D, Cilurzo F, et al. Improved in vitro and in vivo collagen biosynthesis by asiaticoside-loaded ultradeformable vesicles. J Control Release. 2012;162(1):143–151.
    • (2012) J Control Release , vol.162 , Issue.1 , pp. 143-151
    • Paolino, D.1    Cosco, D.2    Cilurzo, F.3
  • 87
    • 0033951387 scopus 로고    scopus 로고
    • Oestradiol skin delivery from ultradeformable liposomes: Refinement of surfactant concentration
    • El Maghraby GM, Williams AC, Barry B W. Oestradiol skin delivery from ultradeformable liposomes: refinement of surfactant concentration. Int J Pharm. 2000;196(1):63–74.
    • (2000) Int J Pharm , vol.196 , Issue.1 , pp. 63-74
    • El Maghraby, G.M.1    Williams, A.C.2    Barry, B.W.3
  • 88
    • 84877881610 scopus 로고    scopus 로고
    • Liposomes containing bile salts as novel ocular delivery systems for tacrolimus (FK506): In vitro characterization and improved corneal permeation
    • Dai Y, Zhou R, Liu L, Lu Y, Qi J, Wu W. Liposomes containing bile salts as novel ocular delivery systems for tacrolimus (FK506): in vitro characterization and improved corneal permeation. Int J Nanomedicine. 2013;8:1921–1933.
    • (2013) Int J Nanomedicine , vol.8 , pp. 1921-1933
    • Dai, Y.1    Zhou, R.2    Liu, L.3    Lu, Y.4    Qi, J.5    Wu, W.6
  • 89
    • 84888095688 scopus 로고    scopus 로고
    • Preparation of cefquinome sulfate proli-posome and its pharmacokinetics in rabbit
    • Fu Q, Fu HL, Huan L, et al. Preparation of cefquinome sulfate proli-posome and its pharmacokinetics in rabbit. Iran J Pharm Res. 2013; 12(4):611–621.
    • (2013) Iran J Pharm Res , vol.12 , Issue.4 , pp. 611-621
    • Fu, Q.1    Fu, H.L.2    Huan, L.3
  • 90
    • 84887225122 scopus 로고    scopus 로고
    • Proliposome powders for enhanced intestinal absorption and bioavailability of raloxifene hydro-chloride: Effect of surface charge
    • Velpula A, Jukanti R, Janga KY, et al. Proliposome powders for enhanced intestinal absorption and bioavailability of raloxifene hydro-chloride: effect of surface charge. Drug Dev Ind Pharm. 2013;39(12): 1895–1906.
    • (2013) Drug Dev Ind Pharm , vol.39 , Issue.12 , pp. 1895-1906
    • Velpula, A.1    Jukanti, R.2    Janga, K.Y.3
  • 91
    • 0025804183 scopus 로고
    • Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells
    • Artursson P, Karlsson J. Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells. Biochem Biophys Res Commun. 1991; 175(3):880–885.
    • (1991) Biochem Biophys Res Commun , vol.175 , Issue.3 , pp. 880-885
    • Artursson, P.1    Karlsson, J.2
  • 93
    • 33845642480 scopus 로고    scopus 로고
    • Mannosylated niosomes as adjuvant-carrier system for oral mucosal immunization
    • Jain S, Vyas SP. Mannosylated niosomes as adjuvant-carrier system for oral mucosal immunization. J Liposome Res. 2006;16(4): 331–345.
    • (2006) J Liposome Res , vol.16 , Issue.4 , pp. 331-345
    • Jain, S.1    Vyas, S.P.2
  • 94
    • 0022519340 scopus 로고
    • M cell transport of Vibrio cholerae from the intestinal lumen into Peyer’s patches: A mechanism for antigen sampling and for microbial transepithelial migration
    • Owen RL, Pierce NF, Apple RT, Cray WC Jr. M cell transport of Vibrio cholerae from the intestinal lumen into Peyer’s patches: a mechanism for antigen sampling and for microbial transepithelial migration. J Infect Dis. 1986;153(6):1108–1118.
    • (1986) J Infect Dis , vol.153 , Issue.6 , pp. 1108-1118
    • Owen, R.L.1    Pierce, N.F.2    Apple, R.T.3    Cray, W.C.4
  • 95
    • 0027474251 scopus 로고
    • Reduced bioavailability of atenolol in man: The role of bile acids
    • Barnwell SG, Laudanski T, Dwyer M, et al. Reduced bioavailability of atenolol in man: the role of bile acids. Int J Pharm. 1993;89(3): 245–250.
    • (1993) Int J Pharm , vol.89 , Issue.3 , pp. 245-250
    • Barnwell, S.G.1    Laudanski, T.2    Dwyer, M.3
  • 96
    • 0035675948 scopus 로고    scopus 로고
    • Effect of bile acids on absorption of nitrendipine in healthy subjects
    • Sasaki M, Maeda A, Sakamoto K, Fujimura A. Effect of bile acids on absorption of nitrendipine in healthy subjects. Br J Clin Pharmacol. 2001;52(6):699–701.
    • (2001) Br J Clin Pharmacol , vol.52 , Issue.6 , pp. 699-701
    • Sasaki, M.1    Maeda, A.2    Sakamoto, K.3    Fujimura, A.4
  • 98
    • 69749108382 scopus 로고    scopus 로고
    • Engineered chylomicron mimicking carrier emulsome for lymph targeted oral delivery of methotrexate
    • Paliwal R, Paliwal SR, Mishra N, Mehta A, Vyas SP. Engineered chylomicron mimicking carrier emulsome for lymph targeted oral delivery of methotrexate. Int J Pharm. 2009;380(1–2):181–188.
    • (2009) Int J Pharm , vol.380 , Issue.1-2 , pp. 181-188
    • Paliwal, R.1    Paliwal, S.R.2    Mishra, N.3    Mehta, A.4    Vyas, S.P.5
  • 99
    • 84875941826 scopus 로고    scopus 로고
    • Characterization and optimization of bilosomes for oral vaccine delivery
    • Wilkhu JS, McNeil SE, Anderson DE, Perrie Y. Characterization and optimization of bilosomes for oral vaccine delivery. J Drug Target. 2013;21(3):291–299.
    • (2013) J Drug Target , vol.21 , Issue.3 , pp. 291-299
    • Wilkhu, J.S.1    McNeil, S.E.2    Erson, D.E.3    Perrie, Y.4
  • 100
    • 84880468991 scopus 로고    scopus 로고
    • Design and optimization of surfactant-based nanovesicles for ocular delivery of Clotrimazole
    • 100. Basha M, Abd El-Alim SH, Shamma RN, Awad GE. Design and optimization of surfactant-based nanovesicles for ocular delivery of Clotrimazole. J Liposome Res. 2013;23(3):203–210.
    • (2013) J Liposome Res , vol.23 , Issue.3 , pp. 203-210
    • Basha, M.1    Abd El-Alim, S.H.2    Shamma, R.N.3    Awad, G.E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.