Integrity and stability of oral liposomes containing bile salts studied in simulated and ex vivo gastrointestinal media

International Journal of Pharmaceutics

Volumn 441, Issue 1-2, 2013, Pages 693-700

  Hu, Shunwen ^a,b   Niu, Mengmeng ^a   Hu, Fuqiang ^c   Lu, Yi ^a   Qi, Jianping ^a   Yin, Zongning ^b   Wu, Wei ^a  

^a FUDAN UNIVERSITY   (China)

^b SICHUAN UNIVERSITY   (China)

^c ZHEJIANG UNIVERSITY   (China)

Author keywords

Entrapment efficiency; Glycocholate; Insulin; Liposomes; Membrane integrity; Oral; Particle size; Stability

Indexed keywords

BILE SALT; CALCEIN; CHOLESTEROL; INSULIN; LIPOSOME; PANCREATIN; PEPSIN A; PHOSPHATIDYLCHOLINE;

ANIMAL EXPERIMENT; ARTICLE; DEGRADATION; DRUG ABSORPTION; ENCAPSULATION; EX VIVO STUDY; GASTROINTESTINAL TRACT; GASTROINTESTINAL TRANSIT; INTESTINE FLUID; MALE; NONHUMAN; PARTICLE SIZE; PH; PRIORITY JOURNAL; RAT; SIMULATION; SOYBEAN;

ADMINISTRATION, ORAL; ANIMALS; CHOLESTEROL; DRUG DELIVERY SYSTEMS; DRUG STABILITY; FLUORESCEINS; GLYCOCHOLIC ACID; INSULIN; LIPOSOMES; MALE; PANCREATIN; PARTICLE SIZE; PEPSIN A; PHOSPHATIDYLCHOLINES; RATS; RATS, WISTAR; SOYBEANS;

EID: 84872763300     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2012.10.025     Document Type: Article

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