Enhanced permeation of triamcinolone acetonide through the buccal mucosa

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 50, Issue 2, 2000, Pages 217-220

  Shin, Sang Chul ^a   Kim, Ja Young ^a  

^a Chonnam National University   (South Korea)

Author keywords

Bioadhesive; Buccal mucosa; Carbopol; Permeation; Poloxamer; Triamcinolone acetonide

Indexed keywords

BILE SALT; CARBOMER; GLYCOL; POLOXAMER; SURFACTANT; TRIAMCINOLONE ACETONIDE;

ANIMAL TISSUE; ARTICLE; CHEEK MUCOSA; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG EFFECT; DRUG FORMULATION; DRUG PENETRATION; DRUG RELEASE; NONHUMAN; SWINE; TEMPERATURE;

ANIMALS; GLUCOCORTICOIDS; MOUTH MUCOSA; PERMEABILITY; POLOXAMER; POLYVINYLS; SOLUBILITY; SWINE; TEMPERATURE; TRIAMCINOLONE ACETONIDE;

EID: 0033844540     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0939-6411(00)00101-6     Document Type: Article

References (10)

1. B.J. Aungst, N.J. Rogers, Comparison of the effects of various transmucosal absorption promoters on buccal insulin delivery, Int. J. Pharm. 53 (1989) 227-235.
2. M. Ishida, Y. Machida, N. Nambu, T. Nagai, New mucosal dosage form of insulin, Chem. Pharm. Bull. 209 (1981) 810-816.
3. I.R. Schmolka, Artificial skin I. Preparation and properties of pluronic F-127 gels for treatment of burns, J. Biomed. Mater. Res. 6 (1972) 571-582.
4. C.W. Cho, S.C. Shin, I.J. Oh, Thermorheological properties of aqueous solutions and gels of poloxamer 407, Drug Dev. Ind. Pharm. 23 (1997) 1227-1232.
5. S.C. Shin, J.Y. Kim, I.J. Oh, Mucoadhesive and physicochemical characteristics of carbopol-poloxamer gels containing triamcinolone acetonide, Drug Dev. Ind. Pharm. 26 (2000) 307-312.
6. S.C. Shin, C.W. Cho, H.K. Choi, Permeation of piroxicam from the poloxamer gels, Drug Dev. Ind. Pharm. 25 (1999) 273-279.
7. A.J. Hoogstraate, S. Senel, C. Cullander, J. Verhoef, H.E. Junginger, H.E. Bodde, Effects of bile salts on transport rates and routes of FITC-labelled compounds across porcine buccal epithelium in vitro, J. Control. Release 40 (1996) 211-221.
8. S. Miyazaku, C. Yokouchi, T. Nakamura, N. Hashiguchi, W.M. Hou, M. Takada, Pluronic F-127 gels as a novel vehicle for rectal administration of indomethacin, Chem. Pharm. Bull. 34 (1986) 1801-1808.
9. G.L. Flynn, S.H. Yalkowsky, T.J. Roseman, Mass transport phenomena and models: theoretical concepts, J. Pharm. Sci. 63 (1974) 479-510.
10. S.W. Hseuh-Ling, S.C. Miller, In vitro release of nicotinic acid alkyl esters from poloxamer vehicles, Int. J. Pharm. 66 (1990) 213-221.