Engineered chylomicron mimicking carrier emulsome for lymph targeted oral delivery of methotrexate

International Journal of Pharmaceutics

Volumn 380, Issue 1-2, 2009, Pages 181-188

  Paliwal, Rishi ^a   Paliwal, Shivani Rai ^a   Mishra, Neeraj ^a   Mehta, Abhinav ^a   Vyas, Suresh P ^a  

^a DR H S GOUR UNIVERSITY   (India)

Author keywords

Bioavailability; Emulsome; Intestinal lymphatics; Methotrexate

Indexed keywords

CHYLOMICRON; EMULSOME; GLYCEROL BEHENATE; LIPOSOME; METHOTREXATE; PHOSPHATIDYLCHOLINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DRUG BIOAVAILABILITY; DRUG FORMULATION; DRUG LYMPH LEVEL; DRUG STABILITY; DRUG STORAGE; FEMALE; INTESTINE FLUID; INTESTINE LYMPH; LYMPHATIC SYSTEM; MALE; MAXIMUM PLASMA CONCENTRATION; MEAN RESIDENCE TIME; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; RAT; TIME TO MAXIMUM PLASMA CONCENTRATION;

ADMINISTRATION, ORAL; ANIMALS; BIOLOGICAL AVAILABILITY; CALORIMETRY, DIFFERENTIAL SCANNING; CHYLOMICRONS; DRUG CARRIERS; DRUG COMPOUNDING; DRUG DELIVERY SYSTEMS; DRUG STABILITY; DRUG STORAGE; EMULSIONS; FEMALE; GASTRIC JUICE; INTESTINAL SECRETIONS; LIPOSOMES; LYMPH; MALE; METHOTREXATE; NANOTECHNOLOGY; PARTICLE SIZE; RATS; RATS, INBRED STRAINS;

EID: 69749108382     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2009.06.026     Document Type: Article

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