A self-assembling nanoparticle for paclitaxel delivery in ovarian cancer

Biomaterials

Volumn 30, Issue 30, 2009, Pages 6006-6016

  Xiao, Kai ^a,b   Luo, Juntao ^a   Fowler, Wiley L ^a   Li, Yuanpei ^a,c   Lee, Joyce S ^a   Xing, Li ^d   Cheng, R Holland ^d   Wang, Li ^b   Lam, Kit S ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b SICHUAN UNIVERSITY   (China)

^c SUN YAT SEN UNIVERSITY   (China)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Amphiphilic linear dendritic copolymer; Biocompatibility; Chemotherapy; Drug delivery; Micelle; Ovarian cancer

Indexed keywords

AMPHIPHILIC LINEAR-DENDRITIC COPOLYMER; AMPHIPHILIC MOLECULES; AMPHIPHILICS; ANTITUMOR EFFECT; AQUEOUS CONDITION; CHEMOTHERAPEUTIC DRUGS; CHOLIC ACIDS; CORE/SHELL; DEEP PENETRATION; HIGH LOADINGS; HYDROPHOBIC DRUG; IN-VITRO; INTRAPERITONEAL; MAXIMUM TOLERATED DOSE; MURINE MODEL; NEAR-INFRARED FLUORESCENCE; ORTHOTOPIC; OVARIAN CANCER; OVARIAN CANCER CELLS; OVARIAN CANCERS; PACLITAXEL; PACLITAXEL DELIVERY; SELF-ASSEMBLING; SERUM ALBUMIN; SIDE EFFECT; SINGLE-DOSE; TUMOR ACCUMULATION; TUMOR TISSUES;

AMINO ACIDS; BIOCOMPATIBILITY; CHEMOTHERAPY; COPOLYMERIZATION; DENDRIMERS; DRUG DELIVERY; DRUG INTERACTIONS; EMULSIFICATION; MICELLES; NANOPARTICLES; POLYETHYLENE OXIDES; TUMORS;

POLYETHYLENE GLYCOLS;

CHOLIC ACID; LYSINE; MACROGOL; NANOPARTICLE; PACLITAXEL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CONTROLLED STUDY; CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG DOSAGE FORM COMPARISON; DRUG EFFICACY; DRUG FORMULATION; DRUG PENETRATION; DRUG RESPONSE; DRUG STRUCTURE; FEMALE; FLUORESCENCE IMAGING; HUMAN; HUMAN CELL; IN VITRO STUDY; MOUSE; NONHUMAN; OVARY CANCER; PRIORITY JOURNAL; REPEATED DRUG DOSE; SINGLE DRUG DOSE; STRUCTURE ANALYSIS; TOXICITY TESTING; TREATMENT DURATION;

ALBUMINS; ANIMALS; ANTINEOPLASTIC AGENTS; BIOCOMPATIBLE MATERIALS; CELL LINE, TUMOR; DRUG DELIVERY SYSTEMS; EMULSIFYING AGENTS; FEMALE; HUMANS; MALE; MAXIMUM TOLERATED DOSE; MICE; MICE, NUDE; NANOPARTICLES; OVARIAN NEOPLASMS; PACLITAXEL; POLYETHYLENE GLYCOLS; SPECTROSCOPY, NEAR-INFRARED;

MURINAE; MUS;

EID: 69249202279     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2009.07.015     Document Type: Article

References (40)

1. Goff B.A., Mandel L., Muntz H.G., and Melancon C.H. Ovarian carcinoma diagnosis. Cancer 89 10 (2000) 2068-2075
2. Rowinsky E.K., Cazenave L.A., and Donehower R.C. Taxol: a novel investigational antimicrotubule agent. J Natl Cancer Inst 82 15 (1990) 1247-1259
3. Anon. Paclitaxel (taxol) for ovarian cancer. Med Lett Drugs Ther 35 896 (1993) 39-40
4. Weiss R.B., Donehower R.C., Wiernik P.H., Ohnuma T., Gralla R.J., Trump D.L., et al. Hypersensitivity reactions from taxol. J Clin Oncol 8 7 (1990) 1263-1268
5. Devalapally H., Duan Z., Seiden M.V., and Amiji M.M. Modulation of drug resistance in ovarian adenocarcinoma by enhancing intracellular ceramide using tamoxifen-loaded biodegradable polymeric nanoparticles. Clin Cancer Res 14 10 (2008) 3193-3203
6. Kingsley J.D., Dou H., Morehead J., Rabinow B., Gendelman H.E., and Destache C.J. Nanotechnology: a focus on nanoparticles as a drug delivery system. J Neuroimmune Pharmacol 1 3 (2006) 340-350
7. Matsumura Y., and Maeda H. A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs. Cancer Res 46 12 Pt 1 (1986) 6387-6392
8. Davis M.E., Chen Z.G., and Shin D.M. Nanoparticle therapeutics: an emerging treatment modality for cancer. Nat Rev Drug Discov 7 9 (2008) 771-782
9. Liu J., Lee H., and Allen C. Formulation of drugs in block copolymer micelles: drug loading and release. Curr Pharm Des 12 36 (2006) 4685-4701
10. Tong R., and Cheng J. Anticancer polymeric nanomedicines. (Philadelphia, PA, United States). Polymer Reviews 47 3 (2007) 345-381
11. Trubetskoy V.S. Polymeric micelles as carriers of diagnostic agents. Adv Drug Deliv Rev 37 1-3 (1999) 81-88
12. Liggins R.T., and Burt H.M. Polyether-polyester diblock copolymers for the preparation of paclitaxel loaded polymeric micelle formulations. Adv Drug Deliv Rev 54 2 (2002) 191-202
13. Le Garrec D., Ranger M., and Leroux J.-C. Micelles in anticancer drug delivery. Am J Drug Deliv 2 1 (2004) 15-42
14. Zhang X., Jackson J.K., and Burt H.M. Development of amphiphilic diblock copolymers as micellar carriers of taxol. Int J Pharm 132 1, 2 (1996) 195-206
15. Ct M., HG L., Me J., and SK A. J Am Chem Soc 116 (1994) 11195
16. van Hest J.C.M., Delnoye D.A.P., Baars M.W.P.L., van Genderen M.H.P., and Meijer E.W. Polystyrene-dendrimer amphiphilic block copolymers with a generation-dependent aggregation. Science 268 5217 (1995) 1592-1595
17. Gillies E.R., Jonsson T.B., and Frechet J.M.J. Stimuli-responsive supramolecular assemblies of linear-dendritic copolymers. J Am Chem Soc 126 38 (2004) 11936-11943
18. Chang Y., Kwon Y.C., Lee S.C., and Kim C. Amphiphilic linear peo-dendritic carbosilane block copolymers. Macromolecules 33 12 (2000) 4496-4500
19. Gitsov I., Wooley K.L., Hawker C.J., Ivanova P.T., and Frechet J.M.J. Synthesis and properties of novel linear-dendritic block copolymers. Reactivity of dendritic macromolecules toward linear polymers. Macromolecules 26 21 (1993) 5621-5627
20. Iyer J., Fleming K., and Hammond P.T. Synthesis and solution properties of new linear-dendritic diblock copolymers. Macromolecules 31 25 (1998) 8757-8765
21. TV P. Self-assembling complexes for gene delivery: from laboratory to clinical trial (1998) 277
22. Lee C.C., Gillies E.R., Fox M.E., Guillaudeu S.J., Frechet J.M., Dy E.E., et al. A single dose of doxorubicin-functionalized bow-tie dendrimer cures mice bearing C-26 colon carcinomas. Proc Natl Acad Sci U S A 103 45 (2006 Nov 7) 16649-16654
23. Gillies E.R., and Frechet J.M. pH-responsive copolymer assemblies for controlled release of doxorubicin. Bioconjugate Chem 16 2 (2005 Mar-Apr) 361-368
24. Vijayalakshmi N., and Maitra U. A simple construction of a bile acid based dendritic light harvesting system. Org Lett 7 13 (2005) 2727-2730
25. Gref R., Minamitake Y., Peracchia M.T., Trubetskoy V., Torchilin V., and Langer R. Biodegradable long-circulating polymeric nanospheres. Science 263 5153 (1994) 1600-1603
26. Blume G., and Cevc G. Liposomes for the sustained drug release in vivo. Biochim Biophys Acta 1029 1 (1990) 91-97
27. Pandey P.S., Rai R., and Singh R.B. Synthesis of cholic acid-based molecular receptors: head-to-head cholaphanes. J Chem Soc Perkin Trans 1 7 (2002) 918-923
28. Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 65 1-2 (1983) 55-63
29. Desai N., Trieu V., Yao Z., Louie L., Ci S., Yang A., et al. Increased antitumor activity, intratumor paclitaxel concentrations, and endothelial cell transport of cremophor-free, albumin-bound paclitaxel, ABI-007, compared with cremophor-based paclitaxel. Clin Cancer Res 12 4 (2006) 1317-1324
30. Bilensoy E., Gurkaynak O., Dogan A.L., and Hincal A.A. Safety and efficacy of amphiphilic beta-cyclodextrin nanoparticles for paclitaxel delivery. Int J Pharm 347 1-2 (2008) 163-170
31. Peng L., Liu R., Marik J., Wang X., Takada Y., and Lam K.S. Combinatorial chemistry identifies high-affinity peptidomimetics against alpha4beta1 integrin for in vivo tumor imaging. Nat Chem Biol 2 7 (2006) 381-389
32. Kim S.C., Kim D.W., Shim Y.H., Bang J.S., Oh H.S., Wan Kim S., et al. In vivo evaluation of polymeric micellar paclitaxel formulation: toxicity and efficacy. J Control Release 72 1-3 (2001) 191-202
33. de Bree E., Theodoropoulos P.A., Rosing H., Michalakis J., Romanos J., Beijnen J.H., et al. Treatment of ovarian cancer using intraperitoneal chemotherapy with taxanes: from laboratory bench to bedside. Cancer Treat Rev 32 6 (2006) 471-482
34. Matsumura Y. Poly(amino acid) micelle nanocarriers in preclinical and clinical studies. Adv Drug Deliv Rev 60 8 (2008) 899-914
35. Cho Y.W., Park S.A., Han T.H., Son D.H., Park J.S., Oh S.J., et al. In vivo tumor targeting and radionuclide imaging with self-assembled nanoparticles: mechanisms, key factors, and their implications. Biomaterials 28 6 (2007) 1236-1247
36. Dreher M.R., Liu W., Michelich C.R., Dewhirst M.W., Yuan F., and Chilkoti A. Tumor vascular permeability, accumulation, and penetration of macromolecular drug carriers. J Natl Cancer Inst 98 5 (2006) 335-344
37. Straubinger R.M., Sharma A., Murray M., and Mayhew E. Novel taxol formulations: taxol-containing liposomes. J Natl Cancer Inst Monogr 15 (1993) 69-78
38. Unezaki S., Maruyama K., Hosoda J., and Nagai I. Direct measurement of the extravasation of polyethylene glycol-coated liposomes into solid tumour tissue by in vivo fluorescence microscopy. Int J Pharm 144 1 (1996) 11-17
39. Sharma A., Sharma U.S., and Straubinger R.M. Paclitaxel-liposomes for intracavitary therapy of intraperitoneal P388 leukemia. Cancer Lett 107 2 (1996) 265-272
40. Tsai M., Lu Z., Wang J., Yeh T.K., Wientjes M.G., and Au J.L. Effects of carrier on disposition and antitumor activity of intraperitoneal paclitaxel. Pharm Res 24 9 (2007) 1691-1701