Deoxycholic acid modified-carboxymethyl curdlan conjugate as a novel carrier of epirubicin: In vitro and in vivo studies

International Journal of Pharmaceutics

Volumn 392, Issue 1-2, 2010, Pages 254-260

  Gao, Fuping ^a   Li, Lei ^a   Zhang, Huizhu ^a,b   Yang, Wenzhi ^a   Chen, Hongli ^a   Zhou, Jing ^c   Zhou, Zhimin ^a   Wang, Yinsong ^d   Cai, Yuanyuan ^c   Li, Xuemin ^a   Liu, Lingrong ^a   Zhang, Qiqing ^a,e  

^a INSTITUTE OF BIOMEDICAL ENGINEERING   (China)

^b NORTH CHINA COAL MEDICAL COLLEGE   (China)

^c BEIJING UNIVERSITY OF CHINESE MEDICINE   (China)

^d TIANJIN MEDICAL UNIVERSITY   (China)

^e XIAMEN UNIVERSITY   (China)

Author keywords

Anti tumor effect; Carboxymethyl curdlan; Deoxycholic acid; Epirubicin; Nanomedicine

Indexed keywords

CARBOXYMETHYL CURDLAN; DEOXYCHOLIC ACID; EPIRUBICIN; NANOCARRIER; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER INHIBITION; CANCER SIZE; CHEMICAL MODIFICATION; CHEMICAL STRUCTURE; COLORIMETRY; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG DISTRIBUTION; DRUG DOSAGE FORM COMPARISON; DRUG EFFICACY; DRUG RELEASE; DRUG TISSUE LEVEL; DRUG UPTAKE; HEART; HUMAN; HUMAN CELL; HYDROPHOBICITY; IN VITRO STUDY; IN VIVO STUDY; KIDNEY PARENCHYMA; MALE; MELANOMA; MOUSE; NONHUMAN; PARTICLE SIZE; PH; PRIORITY JOURNAL; SUSTAINED DRUG RELEASE;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; BETA-GLUCANS; CELL LINE, TUMOR; CELL SURVIVAL; DEOXYCHOLIC ACID; DRUG CARRIERS; DRUG COMPOUNDING; EPIRUBICIN; FLOW CYTOMETRY; HUMANS; HYDROGEN-ION CONCENTRATION; MALE; MELANOMA, EXPERIMENTAL; MICE; MICE, INBRED C57BL; MICROSCOPY, CONFOCAL; MOLECULAR STRUCTURE; NANOPARTICLES; PARTICLE SIZE; SOLUBILITY; TISSUE DISTRIBUTION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 77952742675     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2010.03.044     Document Type: Article

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