Improvement of oxaprozin solubility and permeability by the combined use of cyclodextrin, chitosan, and bile components

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 78, Issue 3, 2011, Pages 385-393

  Maestrelli, F ^a   Cirri, M ^a   Mennini, N ^a   Zerrouk, N ^b   Mura, P ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

^b UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

Bile components; Chitosan; Cyclodextrin; Oxaprozin; Permeability through Caco 2 cells; Solubility

Indexed keywords

BETA CYCLODEXTRIN; CHITOSAN; DEHYDROCHOLIC ACID; OXAPROZIN; SODIUM; URSODEOXYCHOLIC ACID;

ARTICLE; BILE; CELL STRAIN CACO 2; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG MIXTURE; DRUG SOLUBILITY; HUMAN; HUMAN CELL; HUMAN TISSUE; PERMEABILITY; RANDOMIZATION;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BETA-CYCLODEXTRINS; BILE; CACO-2 CELLS; CHITOSAN; CHOLAGOGUES AND CHOLERETICS; DEHYDROCHOLIC ACID; DRUG CARRIERS; DRUG COMPOUNDING; DRUG DELIVERY SYSTEMS; DRUG SYNERGISM; EXCIPIENTS; HUMANS; L-LACTATE DEHYDROGENASE; PERMEABILITY; PROPIONIC ACIDS; SOLUBILITY; URSODEOXYCHOLIC ACID;

EID: 79960609140     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2011.03.012     Document Type: Article

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