RND-type drug efflux pumps from Gram-negative bacteria: Molecular mechanism and inhibition

Frontiers in Microbiology

Volumn 6, Issue APR, 2015, Pages

  Venter, Henrietta ^a   Mowla, Rumana ^a   Ohene Agyei, Thelma ^b   Ma, Shutao ^c  

^a UNIVERSITY OF SOUTH AUSTRALIA   (Australia)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c SHANDONG UNIVERSITY   (China)

Author keywords

Antimicrobial resistance; Drug efflux; Efflux pump inhibitor; Gram negative; Multidrug resistance; Pathogen

Indexed keywords

ANKYRIN; EFFLUX PUMP INHIBITOR; ENZYME INHIBITOR; MEMBRANE FUSION PROTEIN; OUTER MEMBRANE PROTEIN; UNCLASSIFIED DRUG;

ANTIBIOTIC RESISTANCE; BACTERIAL PHENOMENA AND FUNCTIONS; DRUG POTENTIATION; ENZYME INHIBITION; ENZYME SUBSTRATE COMPLEX; GRAM NEGATIVE BACTERIUM; MEMBRANE PERMEABILITY; MEMBRANE TRANSPORT; MINIMUM INHIBITORY CONCENTRATION; MULTIDRUG RESISTANCE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PSEUDOMONAS AERUGINOSA; QUANTITATIVE STRUCTURE ACTIVITY RELATION; REAL TIME POLYMERASE CHAIN REACTION; RESISTANCE NODULATION CELL DIVISION EFFLUX SYSTEM; REVIEW; SURFACE PLASMON RESONANCE;

BACTERIA (MICROORGANISMS); NEGIBACTERIA;

EID: 84930947877     PISSN: None     EISSN: 1664302X     Source Type: Journal    
DOI: 10.3389/fmicb.2015.00377     Document Type: Review

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