Mutations in MexB that affect the efflux of antibiotics with cytoplasmic targets

FEMS Microbiology Letters

Volumn 333, Issue 1, 2012, Pages 20-27

  Ohene Agyei, Thelma ^a   Lea, Jon D ^a   Venter, Henrietta ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Antibiotics; MexB; Multidrug resistance; Pathogen; Pseudomonas aeruginosa; RND transporter

Indexed keywords

BACTERIAL PROTEIN; CIPROFLOXACIN; DOXORUBICIN; ERYTHROMYCIN; ETHIDIUM; MINOCYCLINE; MITOXANTRONE; NALIDIXIC ACID; NORFLOXACIN; NOVOBIOCIN; PROTEIN FAFA; PROTEIN MEXA; PROTEIN MEXB; RHODAMINE 6G; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANTIBIOTIC RESISTANCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; CYTOPLASM; CYTOTOXICITY; ENZYME SPECIFICITY; GENE MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS; PSEUDOMONAS AERUGINOSA; SEQUENCE ALIGNMENT;

ALANINE; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANTI-BACTERIAL AGENTS; BACTERIAL OUTER MEMBRANE PROTEINS; BINDING SITES; BIOLOGICAL TRANSPORT; CELL MEMBRANE; CELL WALL; CYTOPLASM; DRUG RESISTANCE, MULTIPLE, BACTERIAL; ERYTHROMYCIN; ESCHERICHIA COLI; GENES, BACTERIAL; MEMBRANE TRANSPORT PROTEINS; MICROBIAL SENSITIVITY TESTS; MOLECULAR SEQUENCE DATA; MUTATION; PHENYLALANINE; PLASMIDS; PROTEIN STRUCTURE, TERTIARY; PSEUDOMONAS AERUGINOSA; SEQUENCE ALIGNMENT; SUBSTRATE SPECIFICITY;

NEGIBACTERIA; PSEUDOMONAS AERUGINOSA;

EID: 84863835300     PISSN: 03781097     EISSN: 15746968     Source Type: Journal    
DOI: 10.1111/j.1574-6968.2012.02594.x     Document Type: Article

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