Microbial fermentation-derived inhibitors of efflux-pump-mediated drug resistance

Farmaco

Volumn 56, Issue 1-2, 2001, Pages 81-85

  Lee, May D ^a   Galazzo, Jorge L ^a   Staley, Andrew L ^a   Lee, Julie C ^a   Warren, Mark S ^a   Fuernkranz, Hans ^a   Chamberland, Suzanne ^a   Lomovskaya, Olga ^a   Miller, George H ^a  

^a Microcide Pharmaceuticals Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; ANTIBIOTIC AGENT; BEAUVERICIN; EA 371ALPHA; EA 371DELTA; ENNIATIN; FLUCONAZOLE; LEVOFLOXACIN; MILBEMYCIN; NATURAL PRODUCT; POSACONAZOLE; TERBINAFINE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ANTIBIOTIC RESISTANCE; ANTIFUNGAL ACTIVITY; CANDIDA ALBICANS; CONFERENCE PAPER; DRUG ISOLATION; DRUG SCREENING; ENERGY RESOURCE; FERMENTATION; MINIMUM INHIBITORY CONCENTRATION; MULTIDRUG RESISTANCE; NONHUMAN; PSEUDOMONAS AERUGINOSA; STREPTOMYCES;

ANTI-BACTERIAL AGENTS; ATP-BINDING CASSETTE TRANSPORTERS; BACTERIAL OUTER MEMBRANE PROTEINS; CARRIER PROTEINS; DRUG RESISTANCE, MICROBIAL; FERMENTATION; FUNGAL PROTEINS; MEMBRANE TRANSPORT PROTEINS;

EID: 0035273094     PISSN: 0014827X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-827X(01)01002-3     Document Type: Article

References (15)

1. Inactivation of antibiotics and the dissemination of resistance genes
2. Resistance to antibiotics mediated by target alterations
3. Antibacterial efflux systems
4. Antibiotic resistance caused by Gram-negative multidrug efflux pumps
5. Efflux-mediated resistance to antibiotics in bacteria: challenges and opportunities
6. Active efflux mechanisms for antimicrobial resistance
7. Antifungal drug resistance in Candida albicans
8. Mechanisms of resistance to azole antifungal agents in Candida albicans isolates from AIDS patients involve specific multidrug transporters
9. Role of efflux pump(s) in intrinsic resistance of Pseudomonas aeruginosa: active efflux as a contributing factor to β-lactam resistance
10. Use of a genetic approach to evaluate the consequences of inhibition of efflux pump in Pseudomonas aeruginosa
11. Efflux-mediated resistance to fluoroquinolones in Gram-negative bacteria
12. Benastatins A and B, new inhibitors of glutathione S-transferase, produced by Streptomyces sp. M1384-DF12I. Taxonomy, production, isolation, physico-chemical properties and biological activities