-
1
-
-
83555164881
-
HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase
-
Goldstone, D. C., Ennis-Adeniran, V., Hedden, J. J., Groom, H. C., Rice, G. I., Christodoulou, E., Walker, P. A., Kelly, G., Haire, L. F., Yap, M. W., de Carvalho, L. P., Stoye, J. P., Crow, Y. J., Taylor, I. A., and Webb, M. (2011) HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase. Nature 480, 379-382
-
(2011)
Nature
, vol.480
, pp. 379-382
-
-
Goldstone, D.C.1
Ennis-Adeniran, V.2
Hedden, J.J.3
Groom, H.C.4
Rice, G.I.5
Christodoulou, E.6
Walker, P.A.7
Kelly, G.8
Haire, L.F.9
Yap, M.W.10
De Carvalho, L.P.11
Stoye, J.P.12
Crow, Y.J.13
Taylor, I.A.14
Webb, M.15
-
2
-
-
83755162644
-
Aicardi-Goutieres syndrome gene and HIV-1 restriction factor SAMHD1 is a dGTP-regulated deoxynucleotide triphosphohydrolase
-
Powell, R. D., Holland, P. J., Hollis, T., and Perrino, F. W. (2011) Aicardi-Goutieres syndrome gene and HIV-1 restriction factor SAMHD1 is a dGTP-regulated deoxynucleotide triphosphohydrolase. J. Biol. Chem. 286, 43596-43600
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 43596-43600
-
-
Powell, R.D.1
Holland, P.J.2
Hollis, T.3
Perrino, F.W.4
-
3
-
-
84876844698
-
Aicardi-Goutieres syndrome
-
Crow, Y. J. (2013) Aicardi-Goutieres syndrome. Handb. Clin. Neurol. 113, 1629-1635
-
(2013)
Handb. Clin. Neurol.
, vol.113
, pp. 1629-1635
-
-
Crow, Y.J.1
-
4
-
-
84883277795
-
Mouse SAMHD1 has antiretroviral activity and suppresses a spontaneous cell-intrinsic antiviral response
-
Behrendt, R., Schumann, T., Gerbaulet, A., Nguyen, L. A., Schubert, N., Alexopoulou, D., Berka, U., Lienenklaus, S., Peschke, K., Gibbert, K., Wittmann, S., Lindemann, D., Weiss, S., Dahl, A., Naumann, R., et al. (2013) Mouse SAMHD1 has antiretroviral activity and suppresses a spontaneous cell-intrinsic antiviral response. Cell Rep. 4, 689-696
-
(2013)
Cell Rep.
, vol.4
, pp. 689-696
-
-
Behrendt, R.1
Schumann, T.2
Gerbaulet, A.3
Nguyen, L.A.4
Schubert, N.5
Alexopoulou, D.6
Berka, U.7
Lienenklaus, S.8
Peschke, K.9
Gibbert, K.10
Wittmann, S.11
Lindemann, D.12
Weiss, S.13
Dahl, A.14
Naumann, R.15
-
5
-
-
84884291057
-
SAMHD1-dependent retroviral control and escape in mice
-
Rehwinkel, J., Maelfait, J., Bridgeman, A., Rigby, R., Hayward, B., Liberatore, R. A., Bieniasz, P. D., Towers, G. J., Moita, L. F., Crow, Y. J., Bonthron, D. T., and Reis e Sousa, C. (2013) SAMHD1-dependent retroviral control and escape in mice. EMBO J. 32, 2454-2462
-
(2013)
EMBO J.
, vol.32
, pp. 2454-2462
-
-
Rehwinkel, J.1
Maelfait, J.2
Bridgeman, A.3
Rigby, R.4
Hayward, B.5
Liberatore, R.A.6
Bieniasz, P.D.7
Towers, G.J.8
Moita, L.F.9
Crow, Y.J.10
Bonthron, D.T.11
Reis E Sousa, C.12
-
6
-
-
79959858243
-
Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein
-
Hrecka, K., Hao, C., Gierszewska, M., Swanson, S. K., Kesik-Brodacka, M., Srivastava, S., Florens, L., Washburn, M. P., and Skowronski, J. (2011) Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein. Nature 474, 658-661
-
(2011)
Nature
, vol.474
, pp. 658-661
-
-
Hrecka, K.1
Hao, C.2
Gierszewska, M.3
Swanson, S.K.4
Kesik-Brodacka, M.5
Srivastava, S.6
Florens, L.7
Washburn, M.P.8
Skowronski, J.9
-
7
-
-
79959843617
-
SAMHD1 is the dendritic- and myeloid cell-specific HIV-1 restriction factor counteracted by Vpx
-
Laguette, N., Sobhian, B., Casartelli, N., Ringeard, M., Chable-Bessia, C., Ségéral, E., Yatim, A., Emiliani, S., Schwartz, O., and Benkirane, M. (2011) SAMHD1 is the dendritic- and myeloid cell-specific HIV-1 restriction factor counteracted by Vpx. Nature 474, 654-657
-
(2011)
Nature
, vol.474
, pp. 654-657
-
-
Laguette, N.1
Sobhian, B.2
Casartelli, N.3
Ringeard, M.4
Chable-Bessia, C.5
Ségéral, E.6
Yatim, A.7
Emiliani, S.8
Schwartz, O.9
Benkirane, M.10
-
8
-
-
84855272511
-
SAMHD1-deficient CD14M+ cells from individuals with Aicardi-Goutières syndrome are highly susceptible to HIV-1 infection
-
Berger, A., Sommer, A. F., Zwarg, J., Hamdorf, M., Welzel, K., Esly, N., Panitz, S., Reuter, A., Ramos, I., Jatiani, A., Mulder, L. C., Fernandez-Sesma, A., Rutsch, F., Simon, V., König, R., and Flory, E. (2011) SAMHD1-deficient CD14M+ cells from individuals with Aicardi-Goutières syndrome are highly susceptible to HIV-1 infection. PLoS Pathog. 7, e1002425
-
(2011)
PLoS Pathog.
, vol.7
, pp. e1002425
-
-
Berger, A.1
Sommer, A.F.2
Zwarg, J.3
Hamdorf, M.4
Welzel, K.5
Esly, N.6
Panitz, S.7
Reuter, A.8
Ramos, I.9
Jatiani, A.10
Mulder, L.C.11
Fernandez-Sesma, A.12
Rutsch, F.13
Simon, V.14
König, R.15
Flory, E.16
-
9
-
-
84869170593
-
SAMHD1 restricts HIV-1 infection in resting CD4+ T cells
-
Baldauf, H. M., Pan, X., Erikson, E., Schmidt, S., Daddacha, W., Burggraf, M., Schenkova, K., Ambiel, I., Wabnitz, G., Gramberg, T., Panitz, S., Flory, E., Landau, N. R., Sertel, S., Rutsch, F., et al. (2012) SAMHD1 restricts HIV-1 infection in resting CD4+ T cells. Nat. Med. 18, 1682-1687
-
(2012)
Nat. Med.
, vol.18
, pp. 1682-1687
-
-
Baldauf, H.M.1
Pan, X.2
Erikson, E.3
Schmidt, S.4
Daddacha, W.5
Burggraf, M.6
Schenkova, K.7
Ambiel, I.8
Wabnitz, G.9
Gramberg, T.10
Panitz, S.11
Flory, E.12
Landau, N.R.13
Sertel, S.14
Rutsch, F.15
-
10
-
-
84867672682
-
SAMHD1 restricts HIV-1 reverse transcription in quiescent CD4+ T-cells
-
Descours, B., Cribier, A., Chable-Bessia, C., Ayinde, D., Rice, G., Crow, Y., Yatim, A., Schwartz, O., Laguette, N., and Benkirane, M. (2012) SAMHD1 restricts HIV-1 reverse transcription in quiescent CD4+ T-cells. Retrovirology 9, 87
-
(2012)
Retrovirology
, vol.9
, pp. 87
-
-
Descours, B.1
Cribier, A.2
Chable-Bessia, C.3
Ayinde, D.4
Rice, G.5
Crow, Y.6
Yatim, A.7
Schwartz, O.8
Laguette, N.9
Benkirane, M.10
-
11
-
-
84874456119
-
Restriction of diverse retroviruses by SAMHD1
-
Gramberg, T., Kahle, T., Bloch, N., Wittmann, S., Müllers, E., Daddacha, W., Hofmann, H., Kim, B., Lindemann, D., and Landau, N. R. (2013) Restriction of diverse retroviruses by SAMHD1. Retrovirology 10, 26
-
(2013)
Retrovirology
, vol.10
, pp. 26
-
-
Gramberg, T.1
Kahle, T.2
Bloch, N.3
Wittmann, S.4
Müllers, E.5
Daddacha, W.6
Hofmann, H.7
Kim, B.8
Lindemann, D.9
Landau, N.R.10
-
12
-
-
84879511277
-
Host factor SAMHD1 restricts DNA viruses in non-dividing myeloid cells
-
Hollenbaugh, J. A., Gee, P., Baker, J., Daly, M. B., Amie, S. M., Tate, J., Kasai, N., Kanemura, Y., Kim, D. H., Ward, B. M., Koyanagi, Y., and Kim, B. (2013) Host factor SAMHD1 restricts DNA viruses in non-dividing myeloid cells. PLoS Pathog. 9, e1003481
-
(2013)
PLoS Pathog.
, vol.9
, pp. e1003481
-
-
Hollenbaugh, J.A.1
Gee, P.2
Baker, J.3
Daly, M.B.4
Amie, S.M.5
Tate, J.6
Kasai, N.7
Kanemura, Y.8
Kim, D.H.9
Ward, B.M.10
Koyanagi, Y.11
Kim, B.12
-
13
-
-
84926665256
-
SAMHD1 prevents autoimmunity by maintaining genome stability
-
Kretschmer, S., Wolf, C., König, N., Staroske, W., Guck, J., Häusler, M., Luksch, H., Nguyen, L. A., Kim, B., Alexopoulou, D., Dahl, A., Rapp, A., Cardoso, M. C., Shevchenko, A., and Lee-Kirsch, M. A. (2015) SAMHD1 prevents autoimmunity by maintaining genome stability. Ann. Rheum. Dis. 74, e17
-
(2015)
Ann. Rheum. Dis.
, vol.74
, pp. e17
-
-
Kretschmer, S.1
Wolf, C.2
König, N.3
Staroske, W.4
Guck, J.5
Häusler, M.6
Luksch, H.7
Nguyen, L.A.8
Kim, B.9
Alexopoulou, D.10
Dahl, A.11
Rapp, A.12
Cardoso, M.C.13
Shevchenko, A.14
Lee-Kirsch, M.A.15
-
14
-
-
84862777555
-
SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates
-
Lahouassa, H., Daddacha, W., Hofmann, H., Ayinde, D., Logue, E. C., Dragin, L., Bloch, N., Maudet, C., Bertrand, M., Gramberg, T., Pancino, G., Priet, S., Canard, B., Laguette, N., Benkirane, M., et al. (2012) SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates. Nat. Immunol. 13, 223-228
-
(2012)
Nat. Immunol.
, vol.13
, pp. 223-228
-
-
Lahouassa, H.1
Daddacha, W.2
Hofmann, H.3
Ayinde, D.4
Logue, E.C.5
Dragin, L.6
Bloch, N.7
Maudet, C.8
Bertrand, M.9
Gramberg, T.10
Pancino, G.11
Priet, S.12
Canard, B.13
Laguette, N.14
Benkirane, M.15
-
15
-
-
84862654149
-
Tight interplay among SAMHD1 protein level, cellular dNTP levels, and HIV-1 proviral DNA synthesis kinetics in human primary monocyte-derived macrophages
-
Kim, B., Nguyen, L. A., Daddacha, W., and Hollenbaugh, J. A. (2012) Tight interplay among SAMHD1 protein level, cellular dNTP levels, and HIV-1 proviral DNA synthesis kinetics in human primary monocyte-derived macrophages. J. Biol. Chem. 287, 21570-21574
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 21570-21574
-
-
Kim, B.1
Nguyen, L.A.2
Daddacha, W.3
Hollenbaugh, J.A.4
-
16
-
-
33846701783
-
SIVSM/HIV-2 Vpx proteins promote retroviral escape from a proteasome-dependent restriction pathway present in human dendritic cells
-
Goujon, C., Rivière, L., Jarrosson-Wuilleme, L., Bernaud, J., Rigal, D., Darlix, J. L., and Cimarelli, A. (2007) SIVSM/HIV-2 Vpx proteins promote retroviral escape from a proteasome-dependent restriction pathway present in human dendritic cells. Retrovirology 4, 2
-
(2007)
Retrovirology
, vol.4
, pp. 2
-
-
Goujon, C.1
Rivière, L.2
Jarrosson-Wuilleme, L.3
Bernaud, J.4
Rigal, D.5
Darlix, J.L.6
Cimarelli, A.7
-
17
-
-
84857333841
-
Evolutionary and functional analyses of the interaction between the myeloid restriction factor SAMHD1 and the lentiviral Vpx protein
-
Laguette, N., Rahm, N., Sobhian, B., Chable-Bessia, C., Münch, J., Snoeck, J., Sauter, D., Switzer, W. M., Heneine, W., Kirchhoff, F., Delsuc, F., Telenti, A., and Benkirane, M. (2012) Evolutionary and functional analyses of the interaction between the myeloid restriction factor SAMHD1 and the lentiviral Vpx protein. Cell Host Microbe 11, 205-217
-
(2012)
Cell Host Microbe
, vol.11
, pp. 205-217
-
-
Laguette, N.1
Rahm, N.2
Sobhian, B.3
Chable-Bessia, C.4
Münch, J.5
Snoeck, J.6
Sauter, D.7
Switzer, W.M.8
Heneine, W.9
Kirchhoff, F.10
Delsuc, F.11
Telenti, A.12
Benkirane, M.13
-
18
-
-
84857347109
-
The ability of primate lentiviruses to degrade the monocyte restriction factor SAMHD1 preceded the birth of the viral accessory protein Vpx
-
Lim, E. S., Fregoso, O. I., McCoy, C. O., Matsen, F. A., Malik, H. S., and Emerman, M. (2012) The ability of primate lentiviruses to degrade the monocyte restriction factor SAMHD1 preceded the birth of the viral accessory protein Vpx. Cell Host Microbe 11, 194-204
-
(2012)
Cell Host Microbe
, vol.11
, pp. 194-204
-
-
Lim, E.S.1
Fregoso, O.I.2
McCoy, C.O.3
Matsen, F.A.4
Malik, H.S.5
Emerman, M.6
-
20
-
-
83755185577
-
DNA building blocks: Keeping control of manufacture
-
Hofer, A., Crona, M., Logan, D. T., and Sjöberg, B. M. (2012) DNA building blocks: keeping control of manufacture. Crit. Rev. Biochem. Mol. Biol. 47, 50-63
-
(2012)
Crit. Rev. Biochem. Mol. Biol.
, vol.47
, pp. 50-63
-
-
Hofer, A.1
Crona, M.2
Logan, D.T.3
Sjöberg, B.M.4
-
21
-
-
84883397529
-
The deoxynucleotide triphosphohydrolase SAMHD1 is a major regulator ofDNAprecursor pools in mammalian cells
-
Franzolin, E., Pontarin, G., Rampazzo, C., Miazzi, C., Ferraro, P., Palumbo, E., Reichard, P., and Bianchi, V. (2013) The deoxynucleotide triphosphohydrolase SAMHD1 is a major regulator ofDNAprecursor pools in mammalian cells. Proc. Natl. Acad. Sci. U.S.A. 110, 14272-14277
-
(2013)
Proc. Natl. Acad. Sci. U.S.A.
, vol.110
, pp. 14272-14277
-
-
Franzolin, E.1
Pontarin, G.2
Rampazzo, C.3
Miazzi, C.4
Ferraro, P.5
Palumbo, E.6
Reichard, P.7
Bianchi, V.8
-
22
-
-
84899804645
-
GTP activator and dNTP substrates of HIV-1 restriction factor SAMHD1 generate a long-lived activated state
-
Hansen, E. C., Seamon, K. J., Cravens, S. L., and Stivers, J. T. (2014) GTP activator and dNTP substrates of HIV-1 restriction factor SAMHD1 generate a long-lived activated state. Proc. Natl. Acad. Sci. U.S.A. 111, E1843-E1851
-
(2014)
Proc. Natl. Acad. Sci. U.S.A.
, vol.111
, pp. E1843-E1851
-
-
Hansen, E.C.1
Seamon, K.J.2
Cravens, S.L.3
Stivers, J.T.4
-
23
-
-
84883375365
-
GTP is the primary activator of the anti-HIV restriction factor SAMHD1
-
Amie, S. M., Bambara, R. A., and Kim, B. (2013) GTP is the primary activator of the anti-HIV restriction factor SAMHD1. J. Biol. Chem. 288, 25001-25006
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 25001-25006
-
-
Amie, S.M.1
Bambara, R.A.2
Kim, B.3
-
24
-
-
84887445592
-
Mechanism of allosteric activation of SAMHD1 by dGTP
-
Ji, X., Wu, Y., Yan, J., Mehrens, J., Yang, H., DeLucia, M., Hao, C., Gronenborn, A. M., Skowronski, J., Ahn, J., and Xiong, Y. (2013) Mechanism of allosteric activation of SAMHD1 by dGTP. Nat. Struct. Mol. Biol. 20, 1304-1309
-
(2013)
Nat. Struct. Mol. Biol.
, vol.20
, pp. 1304-1309
-
-
Ji, X.1
Wu, Y.2
Yan, J.3
Mehrens, J.4
Yang, H.5
DeLucia, M.6
Hao, C.7
Gronenborn, A.M.8
Skowronski, J.9
Ahn, J.10
Xiong, Y.11
-
25
-
-
84876240156
-
Tetramerization of SAMHD1 is required for biological activity and inhibition of HIV infection
-
Yan, J., Kaur, S., DeLucia, M., Hao, C., Mehrens, J., Wang, C., Golczak, M., Palczewski, K., Gronenborn, A. M., Ahn, J., and Skowronski, J. (2013) Tetramerization of SAMHD1 is required for biological activity and inhibition of HIV infection. J. Biol. Chem. 288, 10406-10417
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 10406-10417
-
-
Yan, J.1
Kaur, S.2
DeLucia, M.3
Hao, C.4
Mehrens, J.5
Wang, C.6
Golczak, M.7
Palczewski, K.8
Gronenborn, A.M.9
Ahn, J.10
Skowronski, J.11
-
26
-
-
84887670233
-
Structural insight into dGTP-dependent activation of tetrameric SAMHD1 deoxynucleoside triphosphate triphosphohydrolase
-
Zhu, C., Gao, W., Zhao, K., Qin, X., Zhang, Y., Peng, X., Zhang, L., Dong, Y., Zhang, W., Li, P., Wei, W., Gong, Y., and Yu, X. F. (2013) Structural insight into dGTP-dependent activation of tetrameric SAMHD1 deoxynucleoside triphosphate triphosphohydrolase. Nat. Commun. 4, 2722
-
(2013)
Nat. Commun.
, vol.4
, pp. 2722
-
-
Zhu, C.1
Gao, W.2
Zhao, K.3
Qin, X.4
Zhang, Y.5
Peng, X.6
Zhang, L.7
Dong, Y.8
Zhang, W.9
Li, P.10
Wei, W.11
Gong, Y.12
Yu, X.F.13
-
27
-
-
84907937909
-
Structural basis of cellular dNTP regulation by SAMHD1
-
Ji, X., Tang, C., Zhao, Q., Wang, W., Xiong, Y. (2014) Structural basis of cellular dNTP regulation by SAMHD1. Proc. Natl. Acad. Sci. U.S.A. 111, E4305-E4314
-
(2014)
Proc. Natl. Acad. Sci. U.S.A.
, vol.111
, pp. E4305-E4314
-
-
Ji, X.1
Tang, C.2
Zhao, Q.3
Wang, W.4
Xiong, Y.5
-
28
-
-
84911389652
-
Structural basis of allosteric activation of sterile - motif and histidine-aspartate domain-containing protein 1 (SAMHD1) by nucleoside triphosphates
-
Koharudin, L. M., Wu, Y., DeLucia, M., Mehrens, J., Gronenborn, A. M., and Ahn, J. (2014) Structural basis of allosteric activation of sterile - motif and histidine-aspartate domain-containing protein 1 (SAMHD1) by nucleoside triphosphates. J. Biol. Chem. 289, 32617-32627
-
(2014)
J. Biol. Chem.
, vol.289
, pp. 32617-32627
-
-
Koharudin, L.M.1
Wu, Y.2
DeLucia, M.3
Mehrens, J.4
Gronenborn, A.M.5
Ahn, J.6
-
29
-
-
84876972365
-
Phosphorylation of SAMHD1 by cyclin A2/CDK1 regulates its restriction activity toward HIV-1
-
Cribier, A., Descours, B., Valadão, A. L., Laguette, N., and Benkirane, M. (2013) Phosphorylation of SAMHD1 by cyclin A2/CDK1 regulates its restriction activity toward HIV-1. Cell Rep. 3, 1036-1043
-
(2013)
Cell Rep.
, vol.3
, pp. 1036-1043
-
-
Cribier, A.1
Descours, B.2
Valadão, A.L.3
Laguette, N.4
Benkirane, M.5
-
30
-
-
84876369203
-
The retroviral restriction ability of SAMHD1, but not its deoxynucleotide triphosphohydrolase activity, is regulated by phosphorylation
-
White, T. E., Brandariz-Nuñez, A., Valle-Casuso, J. C., Amie, S., Nguyen, L. A., Kim, B., Tuzova, M., and Diaz-Griffero, F. (2013) The retroviral restriction ability of SAMHD1, but not its deoxynucleotide triphosphohydrolase activity, is regulated by phosphorylation. Cell Host Microbe 13, 441-451
-
(2013)
Cell Host Microbe
, vol.13
, pp. 441-451
-
-
White, T.E.1
Brandariz-N͡ez, A.2
Valle-Casuso, J.C.3
Amie, S.4
Nguyen, L.A.5
Kim, B.6
Tuzova, M.7
Diaz-Griffero, F.8
-
31
-
-
84905980810
-
Cell cycle control and HIV-1 susceptibility are linked by CDK6-dependent CDK2 phosphorylation of SAMHD1 in myeloid and lymphoid cells
-
Pauls, E., Ruiz, A., Badia, R., Permanyer, M., Gubern, A., Riveira-Muñoz, E., Torres-Torronteras, J., Alvarez, M., Mothe, B., Brander, C., Crespo, M., Menéndez-Arias, L., Clotet, B., Keppler, O. T., Martí, R., et al. (2014) Cell cycle control and HIV-1 susceptibility are linked by CDK6-dependent CDK2 phosphorylation of SAMHD1 in myeloid and lymphoid cells. J. Immunol. 193, 1988-1997
-
(2014)
J. Immunol.
, vol.193
, pp. 1988-1997
-
-
Pauls, E.1
Ruiz, A.2
Badia, R.3
Permanyer, M.4
Gubern, A.5
Riveira-M͡oz, E.6
Torres-Torronteras, J.7
Alvarez, M.8
Mothe, B.9
Brander, C.10
Crespo, M.11
Menéndez-Arias, L.12
Clotet, B.13
Keppler, O.T.14
Martí, R.15
-
32
-
-
19344363916
-
HIV-1 Nef binds the DOCK2-ELMO1 complex to activate rac and inhibit lymphocyte chemotaxis
-
Janardhan, A., Swigut, T., Hill, B., Myers, M. P., and Skowronski, J. (2004) HIV-1 Nef binds the DOCK2-ELMO1 complex to activate rac and inhibit lymphocyte chemotaxis. PLoS Biol. 2, E6
-
(2004)
PLoS Biol.
, vol.2
, pp. E6
-
-
Janardhan, A.1
Swigut, T.2
Hill, B.3
Myers, M.P.4
Skowronski, J.5
-
33
-
-
84859482628
-
HIV/simian immunodeficiency virus (SIV) accessory virulence factor Vpx loads the host cell restriction factor SAMHD1 onto the E3 ubiquitin ligase complex CRL4DCAF1
-
Ahn, J., Hao, C., Yan, J., DeLucia, M., Mehrens, J., Wang, C., Gronenborn, A. M., and Skowronski, J. (2012) HIV/simian immunodeficiency virus (SIV) accessory virulence factor Vpx loads the host cell restriction factor SAMHD1 onto the E3 ubiquitin ligase complex CRL4DCAF1. J. Biol. Chem. 287, 12550-12558
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 12550-12558
-
-
Ahn, J.1
Hao, C.2
Yan, J.3
DeLucia, M.4
Mehrens, J.5
Wang, C.6
Gronenborn, A.M.7
Skowronski, J.8
-
34
-
-
34547395804
-
Lentiviral Vpr usurps Cul4-DDB1[VprBP] E3 ubiquitin ligase to modulate cell cycle
-
Hrecka, K., Gierszewska, M., Srivastava, S., Kozaczkiewicz, L., Swanson, S. K., Florens, L., Washburn, M. P., and Skowronski, J. (2007) Lentiviral Vpr usurps Cul4-DDB1[VprBP] E3 ubiquitin ligase to modulate cell cycle. Proc. Natl. Acad. Sci. U.S.A. 104, 11778-11783
-
(2007)
Proc. Natl. Acad. Sci. U.S.A.
, vol.104
, pp. 11778-11783
-
-
Hrecka, K.1
Gierszewska, M.2
Srivastava, S.3
Kozaczkiewicz, L.4
Swanson, S.K.5
Florens, L.6
Washburn, M.P.7
Skowronski, J.8
-
35
-
-
44449107162
-
Lentiviral Vpx accessory factor targets VprBP/ DCAF1 substrate adaptor for cullin 4 E3 ubiquitin ligase to enable macrophage infection
-
Srivastava, S., Swanson, S. K., Manel, N., Florens, L., Washburn, M. P., and Skowronski, J. (2008) Lentiviral Vpx accessory factor targets VprBP/ DCAF1 substrate adaptor for cullin 4 E3 ubiquitin ligase to enable macrophage infection. PLoS Pathog. 4, e1000059
-
(2008)
PLoS Pathog.
, vol.4
, pp. e1000059
-
-
Srivastava, S.1
Swanson, S.K.2
Manel, N.3
Florens, L.4
Washburn, M.P.5
Skowronski, J.6
-
36
-
-
77949795829
-
Refinements to label free proteome quantitation: How to deal with peptides shared by multiple proteins
-
Zhang, Y., Wen, Z., Washburn, M. P., and Florens, L. (2010) Refinements to label free proteome quantitation: how to deal with peptides shared by multiple proteins. Anal. Chem. 82, 2272-2281
-
(2010)
Anal. Chem.
, vol.82
, pp. 2272-2281
-
-
Zhang, Y.1
Wen, Z.2
Washburn, M.P.3
Florens, L.4
-
37
-
-
0014949207
-
Cleavage of structural proteins during the assembly of the head of bacteriophage T4
-
Laemmli, U. K. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685
-
(1970)
Nature
, vol.227
, pp. 680-685
-
-
Laemmli, U.K.1
-
38
-
-
19944379446
-
Macrophage tropism of HIV-1 depends on efficient cellular dNTP utilization by reverse transcriptase
-
Diamond, T. L., Roshal, M., Jamburuthugoda, V. K., Reynolds, H. M., Merriam, A. R., Lee, K. Y., Balakrishnan, M., Bambara, R. A., Planelles, V., Dewhurst, S., and Kim, B. (2004) Macrophage tropism of HIV-1 depends on efficient cellular dNTP utilization by reverse transcriptase. J. Biol. Chem. 279, 51545-51553
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 51545-51553
-
-
Diamond, T.L.1
Roshal, M.2
Jamburuthugoda, V.K.3
Reynolds, H.M.4
Merriam, A.R.5
Lee, K.Y.6
Balakrishnan, M.7
Bambara, R.A.8
Planelles, V.9
Dewhurst, S.10
Kim, B.11
-
39
-
-
84886932687
-
Restriction of virus infection but not catalytic dNTPase activity is regulated by phosphorylation of SAMHD1
-
Welbourn, S., Dutta, S. M., Semmes, O. J., and Strebel, K. (2013) Restriction of virus infection but not catalytic dNTPase activity is regulated by phosphorylation of SAMHD1. J. Virol. 87, 11516-11524
-
(2013)
J. Virol.
, vol.87
, pp. 11516-11524
-
-
Welbourn, S.1
Dutta, S.M.2
Semmes, O.J.3
Strebel, K.4
-
40
-
-
0029973557
-
Identification of a cyclin-cdk2 recognition motif present in substrates and p21-like cyclin-dependent kinase inhibitors
-
Adams, P. D., Sellers, W. R., Sharma, S. K., Wu, A. D., Nalin, C. M., and Kaelin, W. G., Jr. (1996) Identification of a cyclin-cdk2 recognition motif present in substrates and p21-like cyclin-dependent kinase inhibitors. Mol. Cell. Biol. 16, 6623-6633
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 6623-6633
-
-
Adams, P.D.1
Sellers, W.R.2
Sharma, S.K.3
Wu, A.D.4
Nalin, C.M.5
Kaelin, W.G.6
-
41
-
-
0035910422
-
A bipartite substrate recognition motif for cyclin-dependent kinases
-
Takeda, D. Y., Wohlschlegel, J. A., and Dutta, A. (2001) A bipartite substrate recognition motif for cyclin-dependent kinases. J. Biol. Chem. 276, 1993-1997
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 1993-1997
-
-
Takeda, D.Y.1
Wohlschlegel, J.A.2
Dutta, A.3
-
42
-
-
52649145895
-
GPS 2.0, a tool to predict kinase-specific phosphorylation sites in hierarchy
-
Xue, Y., Ren, J., Gao, X., Jin, C., Wen, L., and Yao, X. (2008) GPS 2.0, a tool to predict kinase-specific phosphorylation sites in hierarchy. Mol. Cell. Proteomics 7, 1598-1608
-
(2008)
Mol. Cell. Proteomics
, vol.7
, pp. 1598-1608
-
-
Xue, Y.1
Ren, J.2
Gao, X.3
Jin, C.4
Wen, L.5
Yao, X.6
-
43
-
-
33646359442
-
Regulation of mammalian ribonucleotide reduction and dNTP pools after DNA damage and in resting cells
-
Håkansson, P., Hofer, A., and Thelander, L. (2006) Regulation of mammalian ribonucleotide reduction and dNTP pools after DNA damage and in resting cells. J. Biol. Chem. 281, 7834-7841
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 7834-7841
-
-
Håkansson, P.1
Hofer, A.2
Thelander, L.3
-
44
-
-
76749114406
-
Essential role of Tip60-dependent recruitment of ribonucleotide reductase at DNA damage sites in DNA repair during G1 phase
-
Niida, H., Katsuno, Y., Sengoku, M., Shimada, M., Yukawa, M., Ikura, M., Ikura, T., Kohno, K., Shima, H., Suzuki, H., Tashiro, S., and Nakanishi, M. (2010) Essential role of Tip60-dependent recruitment of ribonucleotide reductase at DNA damage sites in DNA repair during G1 phase. Genes Dev. 24, 333-338
-
(2010)
Genes Dev.
, vol.24
, pp. 333-338
-
-
Niida, H.1
Katsuno, Y.2
Sengoku, M.3
Shimada, M.4
Yukawa, M.5
Ikura, M.6
Ikura, T.7
Kohno, K.8
Shima, H.9
Suzuki, H.10
Tashiro, S.11
Nakanishi, M.12
-
45
-
-
84883343819
-
Deoxynucleoside triphosphate (dNTP) synthesis and destruction regulate the replication of both cell and virus genomes
-
Stillman, B. (2013) Deoxynucleoside triphosphate (dNTP) synthesis and destruction regulate the replication of both cell and virus genomes. Proc. Natl. Acad. Sci. U.S.A. 110, 14120-14121
-
(2013)
Proc. Natl. Acad. Sci. U.S.A.
, vol.110
, pp. 14120-14121
-
-
Stillman, B.1
-
46
-
-
0032408864
-
The HD domain defines a new superfamily of metal-dependent phosphohydrolases
-
Aravind, L., and Koonin, E. V. (1998) The HD domain defines a new superfamily of metal-dependent phosphohydrolases. Trends Biochem. Sci. 23, 469-472
-
(1998)
Trends Biochem. Sci.
, vol.23
, pp. 469-472
-
-
Aravind, L.1
Koonin, E.V.2
-
47
-
-
84874959500
-
Nuclease activity of the human SAMHD1 protein implicated in the Aicardi-Goutieres syndrome and HIV-1 restriction
-
Beloglazova, N., Flick, R., Tchigvintsev, A., Brown, G., Popovic, A., Nocek, B., and Yakunin, A. F. (2013) Nuclease activity of the human SAMHD1 protein implicated in the Aicardi-Goutieres syndrome and HIV-1 restriction. J. Biol. Chem. 288, 8101-8110
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 8101-8110
-
-
Beloglazova, N.1
Flick, R.2
Tchigvintsev, A.3
Brown, G.4
Popovic, A.5
Nocek, B.6
Yakunin, A.F.7
-
48
-
-
84905732218
-
The ribonuclease activity of SAMHD1 is required for HIV-1 restriction
-
Ryoo, J., Choi, J., Oh, C., Kim, S., Seo, M., Kim, S. Y., Seo, D., Kim, J., White, T. E., Brandariz-Nuñez, A., Diaz-Griffero, F., Yun, C. H., Hollenbaugh, J. A., Kim, B., Baek, D., and Ahn, K. (2014) The ribonuclease activity of SAMHD1 is required for HIV-1 restriction. Nat. Med. 20, 936-941
-
(2014)
Nat. Med.
, vol.20
, pp. 936-941
-
-
Ryoo, J.1
Choi, J.2
Oh, C.3
Kim, S.4
Seo, M.5
Kim, S.Y.6
Seo, D.7
Kim, J.8
White, T.E.9
Brandariz-N͡ez, A.10
Diaz-Griffero, F.11
Yun, C.H.12
Hollenbaugh, J.A.13
Kim, B.14
Baek, D.15
Ahn, K.16
-
49
-
-
36448991500
-
ClustalW and ClustalX version 2.0
-
Larkin, M. A., Blackshields, G., Brown, N. P., Chenna, R., McGettigan, P. A., McWilliam, H., Valentin, F., Wallace, I. M., Wilm, A., Lopez, R., Thompson, J. D., Gibson, T. J., and Higgins, D. G. (2007) ClustalW and ClustalX version 2.0. Bioinformatics 23, 2947-2948
-
(2007)
Bioinformatics
, vol.23
, pp. 2947-2948
-
-
Larkin, M.A.1
Blackshields, G.2
Brown, N.P.3
Chenna, R.4
McGettigan, P.A.5
McWilliam, H.6
Valentin, F.7
Wallace, I.M.8
Wilm, A.9
Lopez, R.10
Thompson, J.D.11
Gibson, T.J.12
Higgins, D.G.13
-
50
-
-
65449188232
-
Jalview Version 2-A multiple sequence alignment editor and analysis workbench
-
Waterhouse, A. M., Procter, J. B., Martin, D. M., Clamp, M., and Barton, G. J. (2009) Jalview Version 2-a multiple sequence alignment editor and analysis workbench. Bioinformatics 25, 1189-1191
-
(2009)
Bioinformatics
, vol.25
, pp. 1189-1191
-
-
Waterhouse, A.M.1
Procter, J.B.2
Martin, D.M.3
Clamp, M.4
Barton, G.J.5
|