The deoxynucleotide triphosphohydrolase SAMHD1 is a major regulator of DNA precursor pools in mammalian cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 35, 2013, Pages 14272-14277

  Franzolin, Elisa ^a   Pontarin, Giovanna ^a   Rampazzo, Chiara ^a   Miazzi, Cristina ^a   Ferraro, Paola ^a   Palumbo, Elisa ^a   Reichard, Peter ^a   Bianchi, Vera ^a  

^a UNIVERSITY OF PADOVA   (Italy)

Author keywords

Cell cycle arrest; DGTP pool; DNTP regulation

Indexed keywords

DEOXYGUANOSINE TRIPHOSPHATE; DEOXYNUCLEOTIDE TRIPHOSPHOHYDROLASE; DEOXYRIBONUCLEOTIDE; PHOSPHATASE; PROTEIN; RIBONUCLEOTIDE REDUCTASE; SAMHD1 PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CATABOLISM; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL CYCLE PROGRESSION; CELL CYCLE REGULATION; CELL CYCLE S PHASE; CELL GROWTH; CELL POPULATION; CELL PROLIFERATION; CONTROLLED STUDY; DNA REPLICATION; DOWN REGULATION; ESCHERICHIA COLI; FIBROBLAST; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOBLOTTING; INNATE IMMUNITY; INTRACELLULAR SPACE; MAMMAL CELL; PRIORITY JOURNAL; PROTEIN FUNCTION; SYNTHESIS; T LYMPHOCYTE; WESTERN BLOTTING;

CELL CYCLE ARREST; DGTP POOL; DNTP REGULATION;

CELL CYCLE; CELL LINE; CELL PROLIFERATION; DNA REPLICATION; GENE SILENCING; HUMANS; MONOMERIC GTP-BINDING PROTEINS; NUCLEIC ACID PRECURSORS; RNA, SMALL INTERFERING;

EID: 84883397529     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1312033110     Document Type: Article

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