Mechanism of allosteric activation of SAMHD1 by dGTP

Nature Structural and Molecular Biology

Volumn 20, Issue 11, 2013, Pages 1304-1309

  Ji, Xiaoyun ^a   Wu, Ying ^b   Yan, Junpeng ^c   Mehrens, Jennifer ^b   Yang, Haitao ^a,d   Delucia, Maria ^b   Hao, Caili ^c   Gronenborn, Angela M ^b   Skowronski, Jacek ^b,c   Ahn, Jinwoo ^b   Xiong, Yong ^a  

^a YALE UNIVERSITY   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d TIANJIN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; DEOXYGUANOSINE TRIPHOSPHATE; STERILE ALPHA MOTIF AND HD DOMAIN CONTAINING PROTEIN 1; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; BIOASSAY; BIOCHEMISTRY; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; PRIORITY JOURNAL; PROTEIN STRUCTURE;

ALLOSTERIC REGULATION; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; DEOXYGUANINE NUCLEOTIDES; HUMANS; MODELS, MOLECULAR; MONOMERIC GTP-BINDING PROTEINS; PROTEIN CONFORMATION; PROTEIN MULTIMERIZATION;

EID: 84887445592     PISSN: 15459993     EISSN: 15459985     Source Type: Journal    
DOI: 10.1038/nsmb.2692     Document Type: Article

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