Ribonucleotide reductases

Annual Review of Biochemistry

Volumn 75, Issue , 2006, Pages 681-706

  Nordlund, Pär ^a   Reichard, Peter ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Allosteric regulation; Deoxyribonucleotide pools; Evolution; Protein radicals

Indexed keywords

AMINO ACID; DEOXYRIBONUCLEOTIDE; DNA; HYDROGEN; NUCLEOSIDE TRIPHOSPHATE; NUCLEOTIDE; OXYGEN; RADICAL; RIBONUCLEOTIDE; RIBONUCLEOTIDE REDUCTASE; RNA;

ALLOSTERISM; AMINO ACID SEQUENCE; CATALYSIS; CONFORMATIONAL TRANSITION; DNA REPAIR; DNA REPLICATION; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME CONFORMATION; ENZYME INHIBITION; ENZYME MECHANISM; ENZYME MODIFICATION; ENZYME REGULATION; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBSTRATE; GENE ACTIVATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DNA BINDING; PROTEIN FAMILY; REGULATORY MECHANISM; REVIEW; SEQUENCE ANALYSIS; STRUCTURAL PROTEOMICS;

ALLOSTERIC REGULATION; ANIMALS; BINDING SITES; EVOLUTION, MOLECULAR; FREE RADICALS; FUNGAL PROTEINS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; MITOCHONDRIA; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PROTEIN CONFORMATION; RIBONUCLEOTIDE REDUCTASES; SUBSTRATE SPECIFICITY; TRANSCRIPTIONAL ACTIVATION;

EID: 33746370368     PISSN: 00664154     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev.biochem.75.103004.142443     Document Type: Review

References (152)

1. Jordan A, Reichard P. 1998. Annu. Rev. Biochem. 67:71-98
2. Fontecave M. 1998. Cell. Mol. Life Sci. 54:684-95
3. Sahlin M, Sjöberg B-M. 2000. Subcell. Biochem. 35:405-43
4. Eklund H, Uhlin U, Farnegardh M, Logan DT, Nordlund P. 2001. Prog. Biophys. Mol. Biol. 77:177-268
5. Kolberg M, Strand KR, Graff P, Andersson KK. 2004. Biochim. Biophys. Acta 1699:1-34
6. Stubbe J. 2003. Curr. Opin. Chem. Biol. 7:183-88
7. Lawrence CC, Stubbe J. 1998. Curr. Opin. Chem. Biol. 2:650-55
8. Eklund H, Fontecave M. 1999. Structure 7:R257-62
9. Frey PA, Booker SJ. 2001. Adv. Protein Chem. 58:1-45
10. Knappe J, Wagner AFV. 2001. Adv. Protein Chem. 58:277-315
11. Fontecave M, Mulliez E, Logan DT. 2002. Prog. Nucleic Acid Res. Mol. Biol. 72:95-127
12. Reichard P. 2002. Arch. Biochem. Biophys. 397:149-55
13. Chabes A, Thelander L. 2003. Cell Cycle 2:171-73
14. Stubbe J. 2000. Curr. Opin. Struct. Biol. 10:731-36
15. Stubbe J, Ge J, Yee CS. 2001. Trends Biochem. Sci. 26:93-99
16. Torrents E, Aloy P, Gibert I, Rodriguez-Trelles F. 2002. J. Mol. Evol. 55:138-52
17. Poole AM, Logan DT, Sjöberg BM. 2002. J. Mol. Evol. 55:180-96
18. Jordan A, Pontis E, Åslund F, Hellman U, Gibert I, Reichard P. 1996. J. Biol. Chem. 271:8779-85
19. Jordan A, Aragall E, Gibert I, Barbe J. 1996. Mol. Microbiol. 19:777-90
20. Aravind L, Wolf YI, Koonin EV. 2000. J. Mol. Microbiol. Biotechnol. 2:191-94
21. Willing A, Follmann H, Auling G. 1988. Eur. J. Biochem. 170:603-11
22. Huque Y, Fieschi F, Torrents E, Gibert I, Eliasson R, et al. 2000. J. Biol. Chem. 275:25365-71
23. Hamilton FD. 1974. J. Biol. Chem. 249:4428-34
24. Masalha M, Borovok I, Schreiber R, Aharonowitz Y, Cohen G. 2001. J. Bacteriol. 183:7260-72
25. Dawes SS, Warner DF, Tsenova L, Timm J, McKinney JD, et al. 2003. Infect. Immun. 71:6124-31
26. Borovok I, Kreisberg-Zakarin R, Yanko M, Schreiber R, Myslovati M, et al. 2002. Microbiology 1489(Part 2):391-404
27. Jordan A, Torrents E, Sala I, Hellman U, Gibert I, Reichard P. 1999. J. Bacteriol. 181:3974-80
28. Borovok I, Gorovitz B, Yanku M, Schreiber R, Gust B, et al. 2004. Mol. Microbiol. 54:1022-35
29. Jordan A, Åslund F, Pontis E, Reichard P, Holmgren A. 1997. J. Biol. Chem. 272:18044-50
30. Tanaka H, Arakawa H, Yamaguchi T, Shiraishi K, Fukuda S, et al. 2000. Nature 404:42-49
31. Nakano K, Balint E, Ashcroft M, Vousden KH. 2000. Oncogene 19:4283-89
32. Nasmyth K. 2001. Annu. Rev. Genet. 35:673-745
33. Guittet O, Håkansson P, Voevodskaya N, Fridd S, Gräslund A, et al. 2001. J. Biol. Chem. 276:40647-51
34. Kimura T, Takeda S, Sagiya Y, Gotoh M, Nakamura Y, Arakawa H. 2003. Nat. Genet. 34:440-45
35. Powell DR, Desai U, Sparks MJ, Hansen G, Gay J, et al. 2005. Pediatr. Nephrol. 20:432-40
36. Elledge SJ, Davis RW. 1990. Genes Dev. 4:740-51
37. Elledge SJ, Davis RW. 1987. Mol. Cell. Biol. 7:2783-93
38. Hurd HK, Roberts CW, Roberts JW. 1987. Mol. Cell. Biol. 7:3673-77
39. Huang MX, Elledge SJ. 1997. Mol. Cell. Biol. 17:6105-13
40. Wang PJ, Chabes A, Casagrande R, Tian XC, Thelander L, Huffaker TC. 1997. Mol. Cell. Biol. 17:6114-21
41. Domkin V, Thelander L, Chabes A. 2002. J. Biol. Chem. 277:18574-78
42. Chabes A, Domkin V, Larsson G, Liu AM, Gräslund A, et al. 2000. Proc. Natl. Acad. Sci. USA 97:2474-79
43. Voegtli WC, Ge J, Perlstein DL, Stubbe J, Rosenzweig AC. 2001. Proc. Natl. Acad. Sci. USA 98:10073-78
44. Ge H, Perlstein DL, Nguyen HH, Bar G, Griffin RG, Stubbe J. 2001. Proc. Natl. Acad. Sci. USA 98:10067-72
45. Torrents E, Trevisiol C, Rotte C, Hellman U, Martin W, Reichard P. 2006. J. Biol. Chem. 281:5604-11 (doi:101074/jbc MS12962200)
46. Bracchi-Ricard V, Moe D, Chakrabarti D. 2005. J. Mol. Biol. 347:749-58
47. Roshick C, Iliffe-Lee ER, McClarty G. 2000. J. Biol. Chem. 275:38111-19
48. McClarty G, Tipples G. 1991. J. Bacteriol. 173:4922-31
49. Tipples G, McClarty G. 1993. Mol. Microbiol. 8:1105-14
50. Högbom M, Stenmark P, Voevodskaya N, McClarty G, Gräslnnd A, Nordlund P. 2004. Science 305:245-48
51. Sintchak MD, Arjara G, Kellogg BA, Stubbe J, Drennan CL. 2002. Nat. Struct. Biol. 9:293-300
52. Larsson KM, Jordan A, Eliasson R, Reichard P, Logan DT, Nordlund P. 2004. Nat. Struct. Mol. Biol. 11:1142-49
53. Logan DT, Andersson J, Sjöberg BM, Nordlund P. 1999. Science 283:1499-504
54. Uhlin U, Eklund H. 1994. Nature 370:533-39
55. Eriksson M, Uhlin U, Ramaswamy S, Ekberg M, Regnström K, et al. 1997. Structure 5:1077-92
56. Uppsten M, Farnegardh M, Jordan A, Eliasson R, Eklund H, Uhlin U. 2003. J. Mol. Biol. 330:87-97
57. Larsson K-M. 2004. Allosteric regulation and radical transfer in ribonucleotide reductase. PhD thesis. Stockholm Univ. 56 pp.
58. Stubbe J, Ator M, Krenitsky T. 1983. J. Biol. Chem. 258:1625-31
59. Persson AL, Sahlin M, Sjöberg BM. 1998. J. Biol. Chem. 273:31016-20
60. Himo F, Siegbahn PEM. 2003. Chem. Rev. 103:2421-56
61. Cho KB, Pelmenschikov V, Gräslund A, Siegbahn PEM. 2004. J. Phys. Chem. B 108:2056-65
62. Pelmenschikov V, Cho KB, Siegbahn PEM. 2004. J. Comp. Chem. 25:311-21
63. Licht S, Gerten GJ, Stubbe JA. 1996. Science 271:477-81
64. Siegbahn PEM. 1998. J. Am. Chem. Soc. 120:8417-29
65. Cho KB, Himo F, Gräslund A, Siegbahn PEM. 2001. J. Phys. Chem. B 105:6445-52
66. Mulliez E, Ollagnier S, Fontecave M, Eliasson R, Reichard P. 1995. Proc. Natl. Acad. Sci. USA 92:8759-62
67. Nordlund P, Eklund H. 1993. J. Mol. Biol. 232:123-64
68. Nordlund P. 2001. In Handbook on Metalloproteins, ed. I Bertini, A Sigel, H Sigel, pp. 320-445. New York: Marcel Dekker
69. Nielsen BB, Kauppi B, Thelander M, Thelander L, Larsen IK, Eklund H. 1995. FEBS Lett. 373:310-12
70. Eriksson M, Jordan A, Eklund H. 1998. Biochemistry 37:13359-69
71. Högbom M, Huque Y, Sjöberg BM, Nordlund P. 2002. Biochemistry 41:1381-89
72. Nordlund P, Sjöberg BM, Eklund H. 1990. Nature 345:593-98
73. Ekberg M, Potsch S, Sandin E, Thunissen M, Nordlund P, et al. 1998. J. Biol. Chem. 273:21003-8
74. Stubbe J, Nocera DG, Yee CS, Chang MC. 2003. Chem. Rev. 103:2167-201
75. Chang MC, Yee CS, Nocera DG, Stubbe J. 2004. J. Am. Chem. Soc. 126:16702-3
76. Kasrayan A, Birgander PL, Pappalardo L, Regnström K, Westman M, et al. 2004. J. Biol. Chem. 279:31050-57
77. Ingemarson R, Thelander L. 1996. Biochemistry 35:8603-9
78. Chen DW, Abend A, Stubbe J, Frey PA. 2003. Biochemistry 42:4578-84
79. Becker A, Fritz-Wolf K, Kabsch W, Knappe J, Schultz S, Wagner AFV. 1999. Nat. Struct. Biol. 6:969-75
80. Becker A, Kabsch W. 2002. J. Biol. Chem. 277:40036-42
81. Sun XY, Harder J, Krook M, Jörnvall H, Sjöberg BM, Reichard P. 1993. Proc. Natl. Acad. Sci. USA 90:577-81
82. Boston T, Atlung T. 2003. J. Bacteriol. 185:5310-13
83. Garriga X, Eliasson R, Torrents E, Jordan A, Barbe J, et al. 1996. Biochem. Biophys. Res. Commun. 229:189-92
84. Jacobson BA, Fuchs JA. 1998. Mol. Microbiol. 28:1315-22
85. Monje-Casas F, Jurado J, Prieto-Alamo MJ, Holmgren A, Pueyo C. 2001. J. Biol. Chem. 276:18031-37
86. Tao H, Bausch C, Richmond C, Blattner FR, Conway T. 1999. J. Bacteriol. 181:6425-40
87. Vassinova N, Kozyrev D. 2000. Microbiology 146(Part 12):3171-82
88. Jordan A, Gibert I, Barbe J. 1994. J. Bacteriol. 176:3420-27
89. Torrents E, Roca I, Gibert I. 2003. Microbiology 149(Part 4):1011-20
90. Torrents E, Poplawski A, Sjöberg BM. 2005. J. Biol. Chem. 280:16571-78
91. Rodionov DA, Vitreschak AG, Mironov AA, Gelfand MS. 2003. J. Biol. Chem. 278:41148-59
92. Rodionov DA, Gelfand MS. 2005. Trends Genet. 21:385-89
93. Johansson E, Hjortsberg K, Thelander L. 1998. J. Biol. Chem. 273:29816-21
94. Chabes AL, Björklund S, Thelander L. 2004. J. Biol. Chem. 279:10796-807
95. Degregori J, Kowalik T, Nevins JR. 1995. Mol. Cell. Biol. 15:4215-24
96. Trimarchi JM, Lees JA. 2002. Nat. Rev. Mol. Cell Biol. 3:11-20
97. Chaboute ME, Clement B, Sekine M, Philipps G, Chaubet-Gigot N. 2000. Plant Cell 12:1987-99
98. Chabes A, Thelander L. 2000. J. Biol. Chem. 275:17747-53
99. Chabes AL, Pfleger CM, Kirschner MW, Thelander L. 2003. Proc. Natl. Acad. Sci. USA 100:3925-29
100. Lin ZP, Belcourt MF, Gory JG, Sartorelli AC. 2004. J. Biol. Chem. 279:27030-38
101. Lozano G, Elleclge SJ. 2000. Nature 404:24-25
102. Zhou BS, Liu XY, Mo XL, Xue LJ, Darwish D, et al. 2003. Cancer Res. 63:6583-94
103. Smith ML, Seo YR. 2002. Mutagenesis 17:149-56
104. Spyrou G, Reichard P. 1983. Biochem. Biophys. Res. Commun. 115:1022-26
105. Huang MX, Zhou Z, Elledge SJ. 1998. Cell 94:595-605
106. Zhao XL, Georgieva B, Chabes A, Domkin V, Ippel JH, et al. 2000. Mol. Cell. Biol. 20:9076-83
107. Chabes A, Domkin V, Thelander L. 1999. J. Biol. Chem. 274:36679-83
108. Chabes A, Georgieva B, Domkin V, Zhao XL, Rothstein R, Thelander L. 2003. Cell 112:391-401
109. Elledge SJ. 1996. Science 274:1664-72
110. Zhao XL, Chabes A, Domkin V, Thelander L, Rothstein R. 2001. EMBO J. 20:3544-53
111. Zhao XL, Rothstein R. 2002. Prof. Natl. Acad. Sci. USA 99:3746-51
112. Saitoh S, Chabes A, McDonald WH, Thelander L, Yates JR, Russell P. 2002. Cell 109:563-73
113. Yao RJ, Zhang Z, An XX, Bucci B, Perlstein DL, et al. 2003. Proc. Natl. Acad. Sci. USA 100:6628-33
114. Sarabia MJF, McInerny C, Harris P, Gordon C, Fantes P. 1993. Mol. Gen. Genet. 238:241-51
115. Liu C, Powell KA, Mundt K, Wu LJ, Carr AM, Caspari T. 2003. Genes Dev. 17:1130-40
116. Nielsen O. 2003. Curr. Biol. 13:R565-67
117. Holmberg C, Fleck O, Hansen HA, Liu C, Slaaby R, et al. 2005. Genes Dev. 19:853-62
118. Håkansson P, Dahlroth SL, Chilikova O, Domkin V, Thelander L. 2005. J. Biol. Chem. 281:1778-83 (doi: 101074/jbcM511716200)
119. Brown NC, Reichard P. 1969. J. Mol. Biol. 46:25-38
120. Brown NC, Reichard P. 1969. J. Mol. Biol. 46:39-55
121. Larsson KM, Andersson J, Sjöberg BM, Norcllund P, Logan DT. 2001. Structure 9:739-50
122. Eriksson S. 1983. J. Biol. Chem. 258:5674-78
123. Chimploy K, Mathews CK. 2001. J. Biol. Chan. 276:7093-100
124. Hofer A, Schmidt PP, Gräslund A, Thelander L. 1997. Proc. Natl. Acad. Sci. USA 94:6959-64
125. Eliasson R, Pontis E, Jordan A, Reichard P. 1999. J. Biol. Chem. 274:7182-89
126. Eliasson R, Pontis E, Sun XY, Reichard P. 1994. J. Biol. Chem. 269:26052-57
127. Torrents E, Buist G, Liu A, Eliasson R, Kok J, et al. 2000. J. Biol. Chem. 275:2463-71
128. Reichard P, Eliasson R, Ingemarson R, Thelander L. 2000. J. Biol. Chem. 275:33021-26
129. Birgander PL, Kasrayan A, Sjöberg BM. 2004. J. Biol. Chem. 279:14496-501
130. Thelander L. 1973. J. Biol. Chem. 248:4591-601
131. Birgander PL, Bug S, Kasrayan A, Dahlroth SL, Westman MA, et al. 2005. J. Biol. Chem. 280:14997-5003
132. Kashlan OB, Cooperman BS. 2003. Biochemistry 42:1696-706
133. Reichard P. 1988. Annu. Rev. Biochem. 57:349-74
134. Bianchi V, Borella S, Rampazzo C, Ferraro P, Calderazzo F, et al. 1997. J. Biol. Chem. 272:16118-24
135. Caspari T. 2000. Curr. Biol. 10:R315-17
136. Gazziola C, Ferraro P, Moras M, Reichard P, Bianchi V. 2001. J. Biol. Chem. 276:6185-90
137. Zhao XL, Muller EGD, Rothstein R. 1998. Mol. Cell 2:329-40
138. Arner ESJ, Eriksson S. 1995. Pharmacol. Ther. 67:155-86
139. Rampazzo C, Gallinaro L, Milanesi E, Frigimelica E, Reichard P, Bianchi V. 2000. Proc. Natl. Acad. Sci. USA 97:8239-44
140. Pontarin G, Gallinaro L, Ferraro P, Reichard P, Bianchi V. 2003. Proc. Natl. Acad. Sci. USA 100:12159-64
141. Bridges EG, Jiang ZL, Cheng YC. 1999. J. Biol. Chem. 274:4620-25
142. Marobbio CMT, Di Noia MA, Palmieri F. 2006. Biochem. J. 393:441-46
143. Rampazzo C, Ferraro P, Pontarin G, Fabris S, Reichard P, Bianchi V. 2004. J. Biol. Chem. 279:17019-26
144. Saada A, Shaag A, Mandel H, Nevo Y, Eriksson S, Elpeleg O. 2001. Nat. Genet. 29:342-44
145. Mandel H, Szargel R, Labay V, Elpeleg O, Saada A, et al. 2001. Nat. Genet. 29:491
146. Nishino I, Spinazzola A, Hirano M. 1999. Science 283:689-92
147. Arpaia E, Benveniste P, Di Cristofano A, Gu YP, Dalai I, et al. 2000. J. Exp. Med. 191:2197-207
148. Nishigaki Y, Marti R, Hirano M. 2004. Hum. Mol. Genet. 13:91-101
149. Nishigaki Y, Marti R, Copeland WC, Hirano M. 2003. J. Clin. Investig. 111:1913-21
150. Reichard P. 1993. Science 260:1773-77
151. Huber C, Wächtershäuser G. 1997. Science 276:245-47
152. Sofia HJ, Chen G, Hetzler BG, Reyes-Spindola JF, Miller NE. 2001. Nucleic Acids Res. 29:1097-106