Tight interplay among SAMHD1 protein level, cellular dNTP levels, and HIV-1 proviral DNA synthesis kinetics in human primary monocyte-derived macrophages

Journal of Biological Chemistry

Volumn 287, Issue 26, 2012, Pages 21570-21574

  Kim, Baek ^a   Nguyen, Laura A ^a   Daddacha, Waaqo ^a   Hollenbaugh, Joseph A ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTI-HIV; DNA METABOLISM; DNA SYNTHESISS; HIV INFECTION; HOST CELLS; MONOCYTE-DERIVED MACROPHAGES; PRE-TREATMENT; PROTEIN LEVEL; REVERSE TRANSCRIPTION; SIMIAN IMMUNODEFICIENCY VIRUS; VIRAL PROTEINS; VIRUS-LIKE PARTICLES;

BIOSYNTHESIS; BODY FLUIDS; DEGRADATION; DNA; KINETICS; MACROPHAGES; VIRUSES;

DISEASES;

HYDROLASE; PROTEIN DNTP; STERILE ALPHA MOTIF DOMAIN AND HD DOMAIN CONTAINING PROTEIN 1; UNCLASSIFIED DRUG; VIRUS DNA; VIRUS VECTOR;

ARTICLE; CELL LEVEL; DNA SYNTHESIS; ENZYME ANALYSIS; ENZYME KINETICS; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; MACROPHAGE; MONOCYTE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DEPLETION; PROTEIN DNA INTERACTION; PROTEIN PROTEIN INTERACTION; REVERSE TRANSCRIPTION; VIRUS CELL INTERACTION; VIRUS LIKE AGENT; VIRUS REPLICATION;

ANTIGENS, CD14; DINUCLEOSIDE PHOSPHATES; DNA REPLICATION; DNA, VIRAL; GREEN FLUORESCENT PROTEINS; HIV-1; HUMANS; KINETICS; MACROPHAGES; MODELS, BIOLOGICAL; MONOMERIC GTP-BINDING PROTEINS; NUCLEOTIDES; POLYMERASE CHAIN REACTION; TIME FACTORS; VIRAL REGULATORY AND ACCESSORY PROTEINS;

EID: 84862654149     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.C112.374843     Document Type: Article

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