SAMHD1 restricts HIV-1 reverse transcription in quiescent CD4 + T-cells

Retrovirology

Volumn 9, Issue , 2012, Pages

  Descours, Benjamin ^a   Cribier, Alexandra ^a   Chable Bessia, Christine ^a   Ayinde, Diana ^c   Rice, Gillian ^b   Crow, Yanick ^b   Yatim, Ahmad ^a   Schwartz, Olivier ^c   Laguette, Nadine ^a   Benkirane, Monsef ^a  

^a INSTITUTE OF HUMAN GENETICS   (France)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c CNRS   (France)

Author keywords

HIV 1; Quiescent CD4 + T cell; Restriction; Reverse transcription; SAMHD1

Indexed keywords

RNA DIRECTED DNA POLYMERASE; SAMHD1 PROTEIN; UNCLASSIFIED DRUG; VIRUS DNA; VIRUS PROTEIN; MONOMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; SAMHD1 PROTEIN, HUMAN;

AICARDI GOUTIERES SYNDROME; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; DNA SYNTHESIS; GENE MUTATION; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INFECTION SENSITIVITY; NONHUMAN; PERIPHERAL LYMPHOCYTE; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION; T CELL DEPLETION; VIRUS LIKE AGENT; HOST PATHOGEN INTERACTION; HUMAN; IMMUNOLOGY; METABOLISM; PATHOGENICITY; VIROLOGY;

HUMAN IMMUNODEFICIENCY VIRUS 1;

CD4-POSITIVE T-LYMPHOCYTES; DNA, VIRAL; HIV-1; HOST-PATHOGEN INTERACTIONS; HUMANS; MONOMERIC GTP-BINDING PROTEINS; REVERSE TRANSCRIPTION; VIRAL REGULATORY AND ACCESSORY PROTEINS;

EID: 84867672682     PISSN: None     EISSN: 17424690     Source Type: Journal    
DOI: 10.1186/1742-4690-9-87     Document Type: Article

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