The three ‘P’s of mitophagy: PARKIN, PINK1, and post-translational modifications

Genes and Development

Volumn 29, Issue 10, 2015, Pages 989-999

  Durcan, Thomas M ^a   Fon, Edward A ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

Deubiquitination; Mitophagy; PARKIN; Phosphorylation; PINK1; Ubiquitin

Indexed keywords

DEUBIQUITINASE; MITOCHONDRIAL ENZYME; PARKIN; PHOSPHOTRANSFERASE; PINK1 PROTEIN; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; PROTEIN KINASE; PTEN-INDUCED PUTATIVE KINASE; UBIQUITIN PROTEIN LIGASE;

AUTOPHOSPHORYLATION; CARBOXY TERMINAL SEQUENCE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; MITOCHONDRIAL DYNAMICS; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL TARGETING SIGNAL; MITOCHONDRION; MITOPHAGY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; REVIEW; RING FINGER MOTIF; UBIQUITINATION; ENZYMOLOGY; GENETICS; METABOLISM; PARKINSON DISEASE; PATHOLOGY; PHOSPHORYLATION; PHYSIOLOGY;

ENZYME ACTIVATION; HUMANS; MITOCHONDRIA; MITOCHONDRIAL DEGRADATION; PARKINSON DISEASE; PHOSPHORYLATION; PROTEIN KINASES; PROTEIN PROCESSING, POST-TRANSLATIONAL; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

EID: 84929582993     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.262758.115     Document Type: Review

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