-
1
-
-
0032499264
-
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
-
Kitada, T., Asakawa, S., Hattori, N., Matsumine, H., Yamamura, Y., Minoshima, S., Yokochi, M., Mizuno, Y., and Shimizu, N. (1998) Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Nature 392, 605-608
-
(1998)
Nature
, vol.392
, pp. 605-608
-
-
Kitada, T.1
Asakawa, S.2
Hattori, N.3
Matsumine, H.4
Yamamura, Y.5
Minoshima, S.6
Yokochi, M.7
Mizuno, Y.8
Shimizu, N.9
-
2
-
-
2442668926
-
Hereditary early-onset Parkinson's disease caused by mutations in PINK1
-
Valente, E. M., Abou-Sleiman, P. M., Caputo, V., Muqit, M. M., Harvey, K., Gispert, S., Ali, Z., Del Turco, D., Bentivoglio, A. R., Healy, D. G., Albanese, A., Nussbaum, R., González-Maldonado, R., Deller, T., Salvi, S., Cortelli, P., Gilks, W. P., Latchman, D. S., Harvey, R. J., Dallapiccola, B., Auburger, G., and Wood, N. W. (2004) Hereditary early-onset Parkinson's disease caused by mutations in PINK1. Science 304, 1158-1160
-
(2004)
Science
, vol.304
, pp. 1158-1160
-
-
Valente, E.M.1
Abou-Sleiman, P.M.2
Caputo, V.3
Muqit, M.M.4
Harvey, K.5
Gispert, S.6
Ali, Z.7
Del Turco, D.8
Bentivoglio, A.R.9
Healy, D.G.10
Albanese, A.11
Nussbaum, R.12
González-Maldonado, R.13
Deller, T.14
Salvi, S.15
Cortelli, P.16
Gilks, W.P.17
Latchman, D.S.18
Harvey, R.J.19
Dallapiccola, B.20
Auburger, G.21
Wood, N.W.22
more..
-
3
-
-
80054787664
-
What genetics tells us about the causes and mechanisms of Parkinson's disease
-
Corti, O., Lesage, S., and Brice, A. (2011) What genetics tells us about the causes and mechanisms of Parkinson's disease. Physiol. Rev. 91, 1161-1218
-
(2011)
Physiol. Rev.
, vol.91
, pp. 1161-1218
-
-
Corti, O.1
Lesage, S.2
Brice, A.3
-
4
-
-
84864150600
-
Mitochondrial dysfunction in Parkinson's disease. Molecular mechanisms and pathophysiological consequences
-
Exner, N., Lutz, A. K., Haass, C., and Winklhofer, K. F. (2012) Mitochondrial dysfunction in Parkinson's disease. Molecular mechanisms and pathophysiological consequences. EMBO J. 31, 3038-3062
-
(2012)
EMBO J.
, vol.31
, pp. 3038-3062
-
-
Exner, N.1
Lutz, A.K.2
Haass, C.3
Winklhofer, K.F.4
-
5
-
-
84867031150
-
Mitochondrial dysfunction associated with increased oxidative stress and-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissue
-
Imaizumi, Y., Okada, Y., Akamatsu, W., Koike, M., Kuzumaki, N., Hayakawa, H., Nihira, T., Kobayashi, T., Ohyama, M., Sato, S., Takanashi, M., Funayama, M., Hirayama, A., Soga, T., Hishiki, T., Suematsu, M., Yagi, T., Ito, D., Kosakai, A., Hayashi, K., Shouji, M., Nakanishi, A., Suzuki, N., Mizuno, Y., Mizushima, N., Amagai, M., Uchiyama, Y., Mochizuki, H., Hattori, N., and Okano, H. (2012) Mitochondrial dysfunction associated with increased oxidative stress and-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissue. Mol. Brain 5, 35
-
(2012)
Mol. Brain
, vol.5
, pp. 35
-
-
Imaizumi, Y.1
Okada, Y.2
Akamatsu, W.3
Koike, M.4
Kuzumaki, N.5
Hayakawa, H.6
Nihira, T.7
Kobayashi, T.8
Ohyama, M.9
Sato, S.10
Takanashi, M.11
Funayama, M.12
Hirayama, A.13
Soga, T.14
Hishiki, T.15
Suematsu, M.16
Yagi, T.17
Ito, D.18
Kosakai, A.19
Hayashi, K.20
Shouji, M.21
Nakanishi, A.22
Suzuki, N.23
Mizuno, Y.24
Mizushima, N.25
Amagai, M.26
Uchiyama, Y.27
Mochizuki, H.28
Hattori, N.29
Okano, H.30
more..
-
6
-
-
77951181836
-
PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy
-
Matsuda, N., Sato, S., Shiba, K., Okatsu, K., Saisho, K., Gautier, C. A., Sou, Y. S., Saiki, S., Kawajiri, S., Sato, F., Kimura, M., Komatsu, M., Hattori, N., and Tanaka, K. (2010) PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy. J. Cell Biol. 189, 211-221
-
(2010)
J. Cell Biol.
, vol.189
, pp. 211-221
-
-
Matsuda, N.1
Sato, S.2
Shiba, K.3
Okatsu, K.4
Saisho, K.5
Gautier, C.A.6
Sou, Y.S.7
Saiki, S.8
Kawajiri, S.9
Sato, F.10
Kimura, M.11
Komatsu, M.12
Hattori, N.13
Tanaka, K.14
-
7
-
-
75749156257
-
PINK1 is selectively stabilized on impaired mitochondria to activate Parkin
-
Narendra, D. P., Jin, S. M., Tanaka, A., Suen, D. F., Gautier, C. A., Shen, J., Cookson, M. R., and Youle, R. J. (2010) PINK1 is selectively stabilized on impaired mitochondria to activate Parkin. PLoS Biol. 8, e1000298
-
(2010)
PLoS Biol.
, vol.8
-
-
Narendra, D.P.1
Jin, S.M.2
Tanaka, A.3
Suen, D.F.4
Gautier, C.A.5
Shen, J.6
Cookson, M.R.7
Youle, R.J.8
-
8
-
-
78649685455
-
Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL
-
Jin, S. M., Lazarou, M., Wang, C., Kane, L. A., Narendra, D. P., and Youle, R. J. (2010) Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL. J. Cell Biol. 191, 933-942
-
(2010)
J. Cell Biol.
, vol.191
, pp. 933-942
-
-
Jin, S.M.1
Lazarou, M.2
Wang, C.3
Kane, L.A.4
Narendra, D.P.5
Youle, R.J.6
-
9
-
-
84859428688
-
Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment
-
Greene, A. W., Grenier, K., Aguileta, M. A., Muise, S., Farazifard, R., Haque, M. E., McBride, H. M., Park, D. S., and Fon, E. A. (2012) Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment. EMBO Rep. 13, 378-385
-
(2012)
EMBO Rep.
, vol.13
, pp. 378-385
-
-
Greene, A.W.1
Grenier, K.2
Aguileta, M.A.3
Muise, S.4
Farazifard, R.5
Haque, M.E.6
McBride, H.M.7
Park, D.S.8
Fon, E.A.9
-
10
-
-
84866072587
-
PINK1 autophosphorylation upon membrane potential dissipation is essential for Parkin recruitment to damaged mitochondria
-
Okatsu, K., Oka, T., Iguchi, M., Imamura, K., Kosako, H., Tani, N., Kimura, M., Go, E., Koyano, F., Funayama, M., Shiba-Fukushima, K., Sato, S., Shimizu, H., Fukunaga, Y., Taniguchi, H., Komatsu, M., Hattori, N., Mihara, K., Tanaka, K., and Matsuda, N. (2012) PINK1 autophosphorylation upon membrane potential dissipation is essential for Parkin recruitment to damaged mitochondria. Nat. Commun. 3, 1016
-
(2012)
Nat. Commun.
, vol.3
, pp. 1016
-
-
Okatsu, K.1
Oka, T.2
Iguchi, M.3
Imamura, K.4
Kosako, H.5
Tani, N.6
Kimura, M.7
Go, E.8
Koyano, F.9
Funayama, M.10
Shiba-Fukushima, K.11
Sato, S.12
Shimizu, H.13
Fukunaga, Y.14
Taniguchi, H.15
Komatsu, M.16
Hattori, N.17
Mihara, K.18
Tanaka, K.19
Matsuda, N.20
more..
-
11
-
-
84868384387
-
Mitochondrial hexokinase HKI is a novel substrate of the Parkin ubiquitin ligase
-
Okatsu, K., Iemura, S., Koyano, F., Go, E., Kimura, M., Natsume, T., Tanaka, K., and Matsuda, N. (2012) Mitochondrial hexokinase HKI is a novel substrate of the Parkin ubiquitin ligase. Biochem. Biophys. Res. Commun. 428, 197-202
-
(2012)
Biochem. Biophys. Res. Commun.
, vol.428
, pp. 197-202
-
-
Okatsu, K.1
Iemura, S.2
Koyano, F.3
Go, E.4
Kimura, M.5
Natsume, T.6
Tanaka, K.7
Matsuda, N.8
-
12
-
-
84868575932
-
Mitochondrial quality control mediated by PINK1 and Parkin. Links to parkinsonism
-
Narendra, D., Walker, J. E., and Youle, R. (2012) Mitochondrial quality control mediated by PINK1 and Parkin. Links to parkinsonism. Cold Spring Harb. Perspect. Biol. 4, a011338
-
(2012)
Cold Spring Harb. Perspect. Biol.
, vol.4
-
-
Narendra, D.1
Walker, J.E.2
Youle, R.3
-
13
-
-
84856741691
-
PINK1 and Parkin to control mitochondria remodeling
-
Koh, H., and Chung, J. (2010) PINK1 and Parkin to control mitochondria remodeling. Anat. Cell Biol. 43, 179-184
-
(2010)
Anat. Cell Biol.
, vol.43
, pp. 179-184
-
-
Koh, H.1
Chung, J.2
-
14
-
-
79952451427
-
Mitophagy. The latest problem for Parkinson's disease
-
Vives-Bauza, C., and Przedborski, S. (2011) Mitophagy. The latest problem for Parkinson's disease. Trends Mol. Med. 17, 158-165
-
(2011)
Trends Mol. Med.
, vol.17
, pp. 158-165
-
-
Vives-Bauza, C.1
Przedborski, S.2
-
15
-
-
79952324644
-
Regulation of PINK1-Parkin-mediated mitophagy
-
Springer, W., and Kahle, P. J. (2011) Regulation of PINK1-Parkin-mediated mitophagy. Autophagy 7, 266-278
-
(2011)
Autophagy
, vol.7
, pp. 266-278
-
-
Springer, W.1
Kahle, P.J.2
-
16
-
-
79961145559
-
Molecular mechanisms of PINK1-related neurodegeneration
-
Pogson, J. H., Ivatt, R. M., and Whitworth, A. J. (2011) Molecular mechanisms of PINK1-related neurodegeneration. Curr. Neurol. Neurosci. Rep. 11, 283-290
-
(2011)
Curr. Neurol. Neurosci. Rep.
, vol.11
, pp. 283-290
-
-
Pogson, J.H.1
Ivatt, R.M.2
Whitworth, A.J.3
-
17
-
-
78650729600
-
Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin
-
Tanaka, A., Cleland, M. M., Xu, S., Narendra, D. P., Suen, D. F., Karbowski, M., and Youle, R. J. (2010) Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin. J. Cell Biol. 191, 1367-1380
-
(2010)
J. Cell Biol.
, vol.191
, pp. 1367-1380
-
-
Tanaka, A.1
Cleland, M.M.2
Xu, S.3
Narendra, D.P.4
Suen, D.F.5
Karbowski, M.6
Youle, R.J.7
-
18
-
-
79954520907
-
Broad activation of the ubiquitin-proteasome system by Parkin is critical for mitophagy
-
Chan, N. C., Salazar, A. M., Pham, A. H., Sweredoski, M. J., Kolawa, N. J., Graham, R. L., Hess, S., and Chan, D. C. (2011) Broad activation of the ubiquitin-proteasome system by Parkin is critical for mitophagy. Hum. Mol. Genet. 20, 1726-1737
-
(2011)
Hum. Mol. Genet.
, vol.20
, pp. 1726-1737
-
-
Chan, N.C.1
Salazar, A.M.2
Pham, A.H.3
Sweredoski, M.J.4
Kolawa, N.J.5
Graham, R.L.6
Hess, S.7
Chan, D.C.8
-
19
-
-
79957472437
-
Parkin mediates proteasome-dependent protein degradation and rupture of the outer mitochondrial membrane
-
Yoshii, S. R., Kishi, C., Ishihara, N., and Mizushima, N. (2011) Parkin mediates proteasome-dependent protein degradation and rupture of the outer mitochondrial membrane. J. Biol. Chem. 286, 19630-19640
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 19630-19640
-
-
Yoshii, S.R.1
Kishi, C.2
Ishihara, N.3
Mizushima, N.4
-
20
-
-
58149314211
-
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
-
Narendra, D., Tanaka, A., Suen, D. F., and Youle, R. J. (2008) Parkin is recruited selectively to impaired mitochondria and promotes their autophagy. J. Cell Biol. 183, 795-803
-
(2008)
J. Cell Biol.
, vol.183
, pp. 795-803
-
-
Narendra, D.1
Tanaka, A.2
Suen, D.F.3
Youle, R.J.4
-
21
-
-
81055140895
-
PINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motility
-
Wang, X., Winter, D., Ashrafi, G., Schlehe, J., Wong, Y. L., Selkoe, D., Rice, S., Steen, J., LaVoie, M. J., and Schwarz, T. L. (2011) PINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motility. Cell 147, 893-906
-
(2011)
Cell
, vol.147
, pp. 893-906
-
-
Wang, X.1
Winter, D.2
Ashrafi, G.3
Schlehe, J.4
Wong, Y.L.5
Selkoe, D.6
Rice, S.7
Steen, J.8
Lavoie, M.J.9
Schwarz, T.L.10
-
22
-
-
84859237566
-
Parkinson's disease-associated kinase PINK1 regulates Miro protein level and axonal transport of mitochondria
-
Liu, S., Sawada, T., Lee, S., Yu, W., Silverio, G., Alapatt, P., Millan, I., Shen, A., Saxton, W., Kanao, T., Takahashi, R., Hattori, N., Imai, Y., and Lu, B. (2012) Parkinson's disease-associated kinase PINK1 regulates Miro protein level and axonal transport of mitochondria. PLoS Genet. 8, e1002537
-
(2012)
PLoS Genet.
, vol.8
-
-
Liu, S.1
Sawada, T.2
Lee, S.3
Yu, W.4
Silverio, G.5
Alapatt, P.6
Millan, I.7
Shen, A.8
Saxton, W.9
Kanao, T.10
Takahashi, R.11
Hattori, N.12
Imai, Y.13
Lu, B.14
-
23
-
-
84873843566
-
Phosphatase and tensin homolog (PTEN)-induced putative kinase 1 (PINK1)-dependent ubiquitination of endogenous Parkin attenuates mitophagy. Study in human primary fibroblasts and induced pluripotent stem cell-derived neurons
-
Rakovic, A., Shurkewitsch, K., Seibler, P., Grünewald, A., Zanon, A., Hagenah, J., Krainc, D., and Klein, C. (2013) Phosphatase and tensin homolog (PTEN)-induced putative kinase 1 (PINK1)-dependent ubiquitination of endogenous Parkin attenuates mitophagy. Study in human primary fibroblasts and induced pluripotent stem cell-derived neurons. J. Biol. Chem. 288, 2223-2237
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 2223-2237
-
-
Rakovic, A.1
Shurkewitsch, K.2
Seibler, P.3
Grünewald, A.4
Zanon, A.5
Hagenah, J.6
Krainc, D.7
Klein, C.8
-
24
-
-
84857462488
-
The yeast complex i equivalent NADH dehydrogenase rescues pink1 mutants
-
Vilain, S., Esposito, G., Haddad, D., Schaap, O., Dobreva, M. P., Vos, M., Van Meensel, S., Morais, V. A., De Strooper, B., and Verstreken, P. (2012) The yeast complex I equivalent NADH dehydrogenase rescues pink1 mutants. PLoS Genet. 8, e1002456
-
(2012)
PLoS Genet.
, vol.8
-
-
Vilain, S.1
Esposito, G.2
Haddad, D.3
Schaap, O.4
Dobreva, M.P.5
Vos, M.6
Van Meensel, S.7
Morais, V.A.8
De Strooper, B.9
Verstreken, P.10
-
25
-
-
84876414704
-
Alternative germ cell death pathway in Drosophila involves HtrA2/Omi, lysosomes, and a caspase-9 counterpart
-
Yacobi-Sharon, K., Namdar, Y., and Arama, E. (2013) Alternative germ cell death pathway in Drosophila involves HtrA2/Omi, lysosomes, and a caspase-9 counterpart. Dev. Cell 25, 29-42
-
(2013)
Dev. Cell
, vol.25
, pp. 29-42
-
-
Yacobi-Sharon, K.1
Namdar, Y.2
Arama, E.3
-
26
-
-
0033933048
-
Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase
-
Shimura, H., Hattori, N., Kubo, Si., Mizuno, Y., Asakawa, S., Minoshima, S., Shimizu, N., Iwai, K., Chiba, T., Tanaka, K., and Suzuki, T. (2000) Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase. Nat. Genet. 25, 302-305
-
(2000)
Nat. Genet.
, vol.25
, pp. 302-305
-
-
Shimura, H.1
Hattori, N.2
Kubo, Si.3
Mizuno, Y.4
Asakawa, S.5
Minoshima, S.6
Shimizu, N.7
Iwai, K.8
Chiba, T.9
Tanaka, K.10
Suzuki, T.11
-
27
-
-
0034700158
-
Parkin functions as an E2-dependent ubiquitin-protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1
-
Zhang, Y., Gao, J., Chung, K. K., Huang, H., Dawson, V. L., and Dawson, T. M. (2000) Parkin functions as an E2-dependent ubiquitin-protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1. Proc. Natl. Acad. Sci. U. S. A. 97, 13354-13359
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 13354-13359
-
-
Zhang, Y.1
Gao, J.2
Chung, K.K.3
Huang, H.4
Dawson, V.L.5
Dawson, T.M.6
-
28
-
-
0034680913
-
Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activity
-
Imai, Y., Soda, M., and Takahashi, R. (2000) Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activity. J. Biol. Chem. 275, 35661-35664
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 35661-35664
-
-
Imai, Y.1
Soda, M.2
Takahashi, R.3
-
29
-
-
79960649509
-
Autoregulation of Parkin activity through its ubiquitin-like domain
-
Chaugule, V. K., Burchell, L., Barber, K. R., Sidhu, A., Leslie, S. J., Shaw, G. S., and Walden, H. (2011) Autoregulation of Parkin activity through its ubiquitin-like domain. EMBO J. 30, 2853-2867
-
(2011)
EMBO J.
, vol.30
, pp. 2853-2867
-
-
Chaugule, V.K.1
Burchell, L.2
Barber, K.R.3
Sidhu, A.4
Leslie, S.J.5
Shaw, G.S.6
Walden, H.7
-
30
-
-
79957517961
-
Parkin mediates apparent E2-independent monoubiquitination in vitro and contains an intrinsic activity that catalyzes polyubiquitination
-
Chew, K. C., Matsuda, N., Saisho, K., Lim, G. G., Chai, C., Tan, H. M., Tanaka, K., and Lim, K. L. (2011) Parkin mediates apparent E2-independent monoubiquitination in vitro and contains an intrinsic activity that catalyzes polyubiquitination. PloS One 6, e19720
-
(2011)
PloS One
, vol.6
-
-
Chew, K.C.1
Matsuda, N.2
Saisho, K.3
Lim, G.G.4
Chai, C.5
Tan, H.M.6
Tanaka, K.7
Lim, K.L.8
-
31
-
-
33645635706
-
Diverse effects of pathogenic mutations of Parkin that catalyze multiple monoubiquitylation in vitro
-
Matsuda, N., Kitami, T., Suzuki, T., Mizuno, Y., Hattori, N., and Tanaka, K. (2006) Diverse effects of pathogenic mutations of Parkin that catalyze multiple monoubiquitylation in vitro. J. Biol. Chem. 281, 3204-3209
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 3204-3209
-
-
Matsuda, N.1
Kitami, T.2
Suzuki, T.3
Mizuno, Y.4
Hattori, N.5
Tanaka, K.6
-
32
-
-
84878775802
-
Structure and Function of Parkin, PINK1, and DJ-1, the three musketeers of neuroprotection
-
Trempe, J. F., and Fon, E. A. (2013) Structure and Function of Parkin, PINK1, and DJ-1, the three musketeers of neuroprotection. Front. Neurol. 4, 38
-
(2013)
Front. Neurol.
, vol.4
, pp. 38
-
-
Trempe, J.F.1
Fon, E.A.2
-
33
-
-
33745280651
-
Biochemical analysis of Parkinson's disease-causing variants of Parkin, an E3 ubiquitin-protein ligase with monoubiquitylation capacity
-
Hampe, C., Ardila-Osorio, H., Fournier, M., Brice, A., and Corti, O. (2006) Biochemical analysis of Parkinson's disease-causing variants of Parkin, an E3 ubiquitin-protein ligase with monoubiquitylation capacity. Hum. Mol. Genet. 15, 2059-2075
-
(2006)
Hum. Mol. Genet.
, vol.15
, pp. 2059-2075
-
-
Hampe, C.1
Ardila-Osorio, H.2
Fournier, M.3
Brice, A.4
Corti, O.5
-
34
-
-
33750219981
-
A ubiquitin ligase complex assembles linear polyubiquitin chains
-
Kirisako, T., Kamei, K., Murata, S., Kato, M., Fukumoto, H., Kanie, M., Sano, S., Tokunaga, F., Tanaka, K., and Iwai, K. (2006) A ubiquitin ligase complex assembles linear polyubiquitin chains. EMBO J. 25, 4877-4887
-
(2006)
EMBO J.
, vol.25
, pp. 4877-4887
-
-
Kirisako, T.1
Kamei, K.2
Murata, S.3
Kato, M.4
Fukumoto, H.5
Kanie, M.6
Sano, S.7
Tokunaga, F.8
Tanaka, K.9
Iwai, K.10
-
35
-
-
0032718068
-
The ubiquitinconjugating enzymes UbcH7 and UbcH8 interact with RING finger/IBR motif-containing domains of HHARI and H7-AP1
-
Moynihan, T. P., Ardley, H. C., Nuber, U., Rose, S. A., Jones, P. F., Markham, A. F., Scheffner, M., and Robinson, P. A. (1999) The ubiquitinconjugating enzymes UbcH7 and UbcH8 interact with RING finger/IBR motif-containing domains of HHARI and H7-AP1. J. Biol. Chem. 274, 30963-30968
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 30963-30968
-
-
Moynihan, T.P.1
Ardley, H.C.2
Nuber, U.3
Rose, S.A.4
Jones, P.F.5
Markham, A.F.6
Scheffner, M.7
Robinson, P.A.8
-
36
-
-
79957949190
-
UBCH7 reactivity profile reveals parkin and HHARI to be RING/HECT hybrids
-
Wenzel, D. M., Lissounov, A., Brzovic, P. S., and Klevit, R. E. (2011) UBCH7 reactivity profile reveals parkin and HHARI to be RING/HECT hybrids. Nature 474, 105-108
-
(2011)
Nature
, vol.474
, pp. 105-108
-
-
Wenzel, D.M.1
Lissounov, A.2
Brzovic, P.S.3
Klevit, R.E.4
-
37
-
-
84867096523
-
The E3 ligase HOIP specifies linear ubiquitin chain assembly through its RING-IBR-RING domain and the unique LDD extension
-
Smit, J. J., Monteferrario, D., Noordermeer, S. M., van Dijk, W. J., van der Reijden, B. A., and Sixma, T. K. (2012) The E3 ligase HOIP specifies linear ubiquitin chain assembly through its RING-IBR-RING domain and the unique LDD extension. EMBO J. 31, 3833-3844
-
(2012)
EMBO J.
, vol.31
, pp. 3833-3844
-
-
Smit, J.J.1
Monteferrario, D.2
Noordermeer, S.M.3
Van Dijk, W.J.4
Van Der Reijden, B.A.5
Sixma, T.K.6
-
38
-
-
84865709638
-
LUBAC synthesizes linear ubiquitin chains via a thioester intermediate
-
Stieglitz, B., Morris-Davies, A. C., Koliopoulos, M. G., Christodoulou, E., and Rittinger, K. (2012) LUBAC synthesizes linear ubiquitin chains via a thioester intermediate. EMBO Rep. 13, 840-846
-
(2012)
EMBO Rep.
, vol.13
, pp. 840-846
-
-
Stieglitz, B.1
Morris-Davies, A.C.2
Koliopoulos, M.G.3
Christodoulou, E.4
Rittinger, K.5
-
39
-
-
84873045973
-
PINK1 drives Parkin self-association and HECT-like E3 activity upstream of mitochondrial binding
-
Lazarou, M., Narendra, D. P., Jin, S. M., Tekle, E., Banerjee, S., and Youle, R. J. (2013) PINK1 drives Parkin self-association and HECT-like E3 activity upstream of mitochondrial binding. J. Cell Biol. 200, 163-172
-
(2013)
J. Cell Biol.
, vol.200
, pp. 163-172
-
-
Lazarou, M.1
Narendra, D.P.2
Jin, S.M.3
Tekle, E.4
Banerjee, S.5
Youle, R.J.6
-
40
-
-
0142227052
-
Retrovirus-mediated gene transfer and expression cloning. Powerful tools in functional genomics
-
Kitamura, T., Koshino, Y., Shibata, F., Oki, T., Nakajima, H., Nosaka, T., and Kumagai, H. (2003) Retrovirus-mediated gene transfer and expression cloning. Powerful tools in functional genomics. Exp. Hematol. 31, 1007-1014
-
(2003)
Exp. Hematol.
, vol.31
, pp. 1007-1014
-
-
Kitamura, T.1
Koshino, Y.2
Shibata, F.3
Oki, T.4
Nakajima, H.5
Nosaka, T.6
Kumagai, H.7
-
41
-
-
49649097747
-
Loss of PINK1 causes mitochondrial functional defects and increased sensitivity to oxidative stress
-
Gautier, C. A., Kitada, T., and Shen, J. (2008) Loss of PINK1 causes mitochondrial functional defects and increased sensitivity to oxidative stress. Proc. Natl. Acad. Sci. U. S. A. 105, 11364-11369
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 11364-11369
-
-
Gautier, C.A.1
Kitada, T.2
Shen, J.3
-
42
-
-
77954695260
-
P62/SQSTM1 cooperates with Parkin for perinuclear clustering of depolarized mitochondria
-
Okatsu, K., Saisho, K., Shimanuki, M., Nakada, K., Shitara, H., Sou, Y. S., Kimura, M., Sato, S., Hattori, N., Komatsu, M., Tanaka, K., and Matsuda, N. (2010) p62/SQSTM1 cooperates with Parkin for perinuclear clustering of depolarized mitochondria. Genes Cell 15, 887-900
-
(2010)
Genes Cell
, vol.15
, pp. 887-900
-
-
Okatsu, K.1
Saisho, K.2
Shimanuki, M.3
Nakada, K.4
Shitara, H.5
Sou, Y.S.6
Kimura, M.7
Sato, S.8
Hattori, N.9
Komatsu, M.10
Tanaka, K.11
Matsuda, N.12
-
43
-
-
77950384477
-
Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin
-
Ziviani, E., Tao, R. N., and Whitworth, A. J. (2010) Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin. Proc. Natl. Acad. Sci. U. S. A. 107, 5018-5023
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, pp. 5018-5023
-
-
Ziviani, E.1
Tao, R.N.2
Whitworth, A.J.3
-
44
-
-
78649463381
-
Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy
-
Gegg, M. E., Cooper, J. M., Chau, K. Y., Rojo, M., Schapira, A. H., and Taanman, J. W. (2010) Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy. Hum. Mol. Genet. 19, 4861-4870
-
(2010)
Hum. Mol. Genet.
, vol.19
, pp. 4861-4870
-
-
Gegg, M.E.1
Cooper, J.M.2
Chau, K.Y.3
Rojo, M.4
Schapira, A.H.5
Taanman, J.W.6
-
45
-
-
79960493052
-
Parkin promotes the ubiquitination and degradation of the mitochondrial fusion factor mitofusin 1
-
Glauser, L., Sonnay, S., Stafa, K., and Moore, D. J. (2011) Parkin promotes the ubiquitination and degradation of the mitochondrial fusion factor mitofusin 1. J. Neurochem. 118, 636-645
-
(2011)
J. Neurochem.
, vol.118
, pp. 636-645
-
-
Glauser, L.1
Sonnay, S.2
Stafa, K.3
Moore, D.J.4
-
46
-
-
84868087279
-
ROS-dependent regulation of Parkin and DJ-1 localization during oxidative stress in neurons
-
Joselin, A. P., Hewitt, S. J., Callaghan, S. M., Kim, R. H., Chung, Y. H., Mak, T. W., Shen, J., Slack, R. S., and Park, D. S. (2012) ROS-dependent regulation of Parkin and DJ-1 localization during oxidative stress in neurons. Hum. Mol. Genet. 21, 4888-4903
-
(2012)
Hum. Mol. Genet.
, vol.21
, pp. 4888-4903
-
-
Joselin, A.P.1
Hewitt, S.J.2
Callaghan, S.M.3
Kim, R.H.4
Chung, Y.H.5
Mak, T.W.6
Shen, J.7
Slack, R.S.8
Park, D.S.9
-
47
-
-
65649126339
-
Ubiquitin C-terminal electrophiles are activity-based probes for identification and mechanistic study of ubiquitin conjugating machinery
-
Love, K. R., Pandya, R. K., Spooner, E., and Ploegh, H. L. (2009) Ubiquitin C-terminal electrophiles are activity-based probes for identification and mechanistic study of ubiquitin conjugating machinery. ACS Chem. Biol. 4, 275-287
-
(2009)
ACS Chem. Biol.
, vol.4
, pp. 275-287
-
-
Love, K.R.1
Pandya, R.K.2
Spooner, E.3
Ploegh, H.L.4
-
48
-
-
10744227299
-
Specific and covalent targeting of conjugating and deconjugating enzymes of ubiquitin-like proteins
-
Hemelaar, J., Borodovsky, A., Kessler, B. M., Reverter, D., Cook, J., Kolli, N., Gan-Erdene, T., Wilkinson, K. D., Gill, G., Lima, C. D., Ploegh, H. L., and Ovaa, H. (2004) Specific and covalent targeting of conjugating and deconjugating enzymes of ubiquitin-like proteins. Mol. Cell. Biol. 24, 84-95
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 84-95
-
-
Hemelaar, J.1
Borodovsky, A.2
Kessler, B.M.3
Reverter, D.4
Cook, J.5
Kolli, N.6
Gan-Erdene, T.7
Wilkinson, K.D.8
Gill, G.9
Lima, C.D.10
Ploegh, H.L.11
Ovaa, H.12
-
49
-
-
79955073027
-
Parkin, a top level manager in the cell's sanitation department
-
Rankin, C. A., Roy, A., Zhang, Y., and Richter, M. (2011) Parkin, a top level manager in the cell's sanitation department. Open Biochem. J. 5, 9-26
-
(2011)
Open Biochem. J.
, vol.5
, pp. 9-26
-
-
Rankin, C.A.1
Roy, A.2
Zhang, Y.3
Richter, M.4
-
50
-
-
84879251778
-
Structure of parkin reveals mechanisms for ubiquitin ligase activation
-
Trempé, J. F., Sauvé, V., Grenier, K., Seirafi, M., Tang, M. Y., Ménade, M., Al-Abdul-Wahid, S., Krett, J., Wong, K., Kozlov, G., Nagar, B., Fon, E. A., and Gehring, K. (2013) Structure of parkin reveals mechanisms for ubiquitin ligase activation. Science 340, 1451-1455
-
(2013)
Science
, vol.340
, pp. 1451-1455
-
-
Trempé, J.F.1
Sauvé, V.2
Grenier, K.3
Seirafi, M.4
Tang, M.Y.5
Ménade, M.6
Al-Abdul-Wahid, S.7
Krett, J.8
Wong, K.9
Kozlov, G.10
Nagar, B.11
Fon, E.A.12
Gehring, K.13
-
51
-
-
50149121528
-
The kinase domain of mitochondrial PINK1 faces the cytoplasm
-
Zhou, C., Huang, Y., Shao, Y., May, J., Prou, D., Perier, C., Dauer, W., Schon, E. A., and Przedborski, S. (2008) The kinase domain of mitochondrial PINK1 faces the cytoplasm. Proc. Natl. Acad. Sci. U. S. A. 105, 12022-12027
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 12022-12027
-
-
Zhou, C.1
Huang, Y.2
Shao, Y.3
May, J.4
Prou, D.5
Perier, C.6
Dauer, W.7
Schon, E.A.8
Przedborski, S.9
-
52
-
-
17644365438
-
Mutations in PTEN-induced putative kinase 1 associated with recessive parkinsonism have differential effects on protein stability
-
Beilina, A., Van Der Brug, M., Ahmad, R., Kesavapany, S., Miller, D. W., Petsko, G. A., and Cookson, M. R. (2005) Mutations in PTEN-induced putative kinase 1 associated with recessive parkinsonism have differential effects on protein stability. Proc. Natl. Acad. Sci. U. S. A. 102, 5703-5708
-
(2005)
Proc. Natl. Acad. Sci. U. S. A.
, vol.102
, pp. 5703-5708
-
-
Beilina, A.1
Van Der Brug, M.2
Ahmad, R.3
Kesavapany, S.4
Miller, D.W.5
Petsko, G.A.6
Cookson, M.R.7
-
53
-
-
4444274910
-
PINK1 mutations are associated with sporadic early-onset parkinsonism
-
Valente, E. M., Salvi, S., Ialongo, T., Marongiu, R., Elia, A. E., Caputo, V., Romito, L., Albanese, A., Dallapiccola, B., and Bentivoglio, A. R. (2004) PINK1 mutations are associated with sporadic early-onset parkinsonism. Ann. Neurol. 56, 336-341
-
(2004)
Ann. Neurol.
, vol.56
, pp. 336-341
-
-
Valente, E.M.1
Salvi, S.2
Ialongo, T.3
Marongiu, R.4
Elia, A.E.5
Caputo, V.6
Romito, L.7
Albanese, A.8
Dallapiccola, B.9
Bentivoglio, A.R.10
-
54
-
-
77949478474
-
Phosphorylation of parkin by Parkinson disease-linked kinase PINK1 activates parkin E3 ligase function and NF-κB signaling
-
Sha, D., Chin, L. S., and Li, L. (2010) Phosphorylation of parkin by Parkinson disease-linked kinase PINK1 activates parkin E3 ligase function and NF-κB signaling. Hum. Mol. Genet. 19, 352-363
-
(2010)
Hum. Mol. Genet.
, vol.19
, pp. 352-363
-
-
Sha, D.1
Chin, L.S.2
Li, L.3
-
55
-
-
75949098487
-
PINK1-dependent recruitment of Parkin to mitochondria in mitophagy
-
Vives-Bauza, C., Zhou, C., Huang, Y., Cui, M., de Vries, R. L., Kim, J., May, J., Tocilescu, M. A., Liu, W., Ko, H. S., Magrané, J., Moore, D. J., Dawson, V. L., Grailhe, R., Dawson, T. M., Li, C., Tieu, K., and Przedborski, S. (2010) PINK1-dependent recruitment of Parkin to mitochondria in mitophagy. Proc. Natl. Acad. Sci. U. S. A. 107, 378-383
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, pp. 378-383
-
-
Vives-Bauza, C.1
Zhou, C.2
Huang, Y.3
Cui, M.4
De Vries, R.L.5
Kim, J.6
May, J.7
Tocilescu, M.A.8
Liu, W.9
Ko, H.S.10
Magrané, J.11
Moore, D.J.12
Dawson, V.L.13
Grailhe, R.14
Dawson, T.M.15
Li, C.16
Tieu, K.17
Przedborski, S.18
-
56
-
-
84864267876
-
PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating serine 65
-
Kondapalli, C., Kazlauskaite, A., Zhang, N., Woodroof, H. I., Campbell, D. G., Gourlay, R., Burchell, L., Walden, H., Macartney, T. J., Deak, M., Knebel, A., Alessi, D. R., and Muqit, M. M. (2012) PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating serine 65. Open Biol. 2, 120080
-
(2012)
Open Biol.
, vol.2
, pp. 120080
-
-
Kondapalli, C.1
Kazlauskaite, A.2
Zhang, N.3
Woodroof, H.I.4
Campbell, D.G.5
Gourlay, R.6
Burchell, L.7
Walden, H.8
Macartney, T.J.9
Deak, M.10
Knebel, A.11
Alessi, D.R.12
Muqit, M.M.13
-
57
-
-
33645714857
-
Phosphate-binding tag, a new tool to visualize phosphorylated proteins
-
Kinoshita, E., Kinoshita-Kikuta, E., Takiyama, K., and Koike, T. (2006) Phosphate-binding tag, a new tool to visualize phosphorylated proteins. Mol. Cell. Proteomics 5, 749-757
-
(2006)
Mol. Cell. Proteomics
, vol.5
, pp. 749-757
-
-
Kinoshita, E.1
Kinoshita-Kikuta, E.2
Takiyama, K.3
Koike, T.4
-
58
-
-
84855963980
-
Phos-tag SDSPAGE systems for phosphorylation profiling of proteins with a wide range of molecular masses under neutral pH conditions
-
Kinoshita, E., Kinoshita-Kikuta, E., and Koike, T. (2012) Phos-tag SDSPAGE systems for phosphorylation profiling of proteins with a wide range of molecular masses under neutral pH conditions. Proteomics 12, 192-202
-
(2012)
Proteomics
, vol.12
, pp. 192-202
-
-
Kinoshita, E.1
Kinoshita-Kikuta, E.2
Koike, T.3
-
59
-
-
0344441899
-
Alterations in the common fragile site gene Parkin in ovarian and other cancers
-
Denison, S. R., Wang, F., Becker, N. A., Schüle, B., Kock, N., Phillips, L. A., Klein, C., and Smith, D. I. (2003) Alterations in the common fragile site gene Parkin in ovarian and other cancers. Oncogene 22, 8370-8378
-
(2003)
Oncogene
, vol.22
, pp. 8370-8378
-
-
Denison, S.R.1
Wang, F.2
Becker, N.A.3
Schüle, B.4
Kock, N.5
Phillips, L.A.6
Klein, C.7
Smith, D.I.8
-
60
-
-
10744224951
-
Novel monoclonal antibodies demonstrate biochemical variation of brain parkin with age
-
Pawlyk, A. C., Giasson, B. I., Sampathu, D. M., Perez, F. A., Lim, K. L., Dawson, V. L., Dawson, T. M., Palmiter, R. D., Trojanowski, J. Q., and Lee, V. M. (2003) Novel monoclonal antibodies demonstrate biochemical variation of brain parkin with age. J. Biol. Chem. 278, 48120-48128
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 48120-48128
-
-
Pawlyk, A.C.1
Giasson, B.I.2
Sampathu, D.M.3
Perez, F.A.4
Lim, K.L.5
Dawson, V.L.6
Dawson, T.M.7
Palmiter, R.D.8
Trojanowski, J.Q.9
Lee, V.M.10
-
61
-
-
84871891737
-
PINK1-mediated phosphorylation of the Parkin ubiquitin-like domain primes mitochondrial translocation of Parkin and regulates mitophagy
-
Shiba-Fukushima, K., Imai, Y., Yoshida, S., Ishihama, Y., Kanao, T., Sato, S., and Hattori, N. (2012) PINK1-mediated phosphorylation of the Parkin ubiquitin-like domain primes mitochondrial translocation of Parkin and regulates mitophagy. Sci. Rep. 2, 1002
-
(2012)
Sci. Rep.
, vol.2
, pp. 1002
-
-
Shiba-Fukushima, K.1
Imai, Y.2
Yoshida, S.3
Ishihama, Y.4
Kanao, T.5
Sato, S.6
Hattori, N.7
-
62
-
-
13544266179
-
Parkin phosphorylation and modulation of its E3 ubiquitin ligase activity
-
Yamamoto, A., Friedlein, A., Imai, Y., Takahashi, R., Kahle, P. J., and Haass, C. (2005) Parkin phosphorylation and modulation of its E3 ubiquitin ligase activity. J. Biol. Chem. 280, 3390-3399
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 3390-3399
-
-
Yamamoto, A.1
Friedlein, A.2
Imai, Y.3
Takahashi, R.4
Kahle, P.J.5
Haass, C.6
-
63
-
-
60549088301
-
Combined kinase inhibition modulates parkin inactivation
-
Rubio de la Torre, E., Luzón-Toro, B., Forte-Lago, I., Minguez-Castellanos, A., Ferrer, I., and Hilfiker, S. (2009) Combined kinase inhibition modulates parkin inactivation. Hum. Mol. Genet. 18, 809-823
-
(2009)
Hum. Mol. Genet.
, vol.18
, pp. 809-823
-
-
Rubio De La Torre, E.1
Luzón-Toro, B.2
Forte-Lago, I.3
Minguez-Castellanos, A.4
Ferrer, I.5
Hilfiker, S.6
-
64
-
-
78650466243
-
A tissue-specific atlas of mouse protein phosphorylation and expression
-
Huttlin, E. L., Jedrychowski, M. P., Elias, J. E., Goswami, T., Rad, R., Beausoleil, S. A., Villén, J., Haas, W., Sowa, M. E., and Gygi, S. P. (2010) A tissue-specific atlas of mouse protein phosphorylation and expression. Cell 143, 1174-1189
-
(2010)
Cell
, vol.143
, pp. 1174-1189
-
-
Huttlin, E.L.1
Jedrychowski, M.P.2
Elias, J.E.3
Goswami, T.4
Rad, R.5
Beausoleil, S.A.6
Villén, J.7
Haas, W.8
Sowa, M.E.9
Gygi, S.P.10
-
65
-
-
34250344611
-
Phosphorylation of Parkin by the cyclin-dependent kinase 5 at the linker region modulates its ubiquitin-ligase activity and aggregation
-
Avraham, E., Rott, R., Liani, E., Szargel, R., and Engelender, S. (2007) Phosphorylation of Parkin by the cyclin-dependent kinase 5 at the linker region modulates its ubiquitin-ligase activity and aggregation. J. Biol. Chem. 282, 12842-12850
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 12842-12850
-
-
Avraham, E.1
Rott, R.2
Liani, E.3
Szargel, R.4
Engelender, S.5
-
66
-
-
56049091236
-
PINK1 controls mitochondrial localization of Parkin through direct phosphorylation
-
Kim, Y., Park, J., Kim, S., Song, S., Kwon, S. K., Lee, S. H., Kitada, T., Kim, J. M., and Chung, J. (2008) PINK1 controls mitochondrial localization of Parkin through direct phosphorylation. Biochem. Biophys. Res. Commun. 377, 975-980
-
(2008)
Biochem. Biophys. Res. Commun.
, vol.377
, pp. 975-980
-
-
Kim, Y.1
Park, J.2
Kim, S.3
Song, S.4
Kwon, S.K.5
Lee, S.H.6
Kitada, T.7
Kim, J.M.8
Chung, J.9
-
68
-
-
33745602748
-
Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin
-
Park, J., Lee, S. B., Lee, S., Kim, Y., Song, S., Kim, S., Bae, E., Kim, J., Shong, M., Kim, J. M., and Chung, J. (2006) Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin. Nature 441, 1157-1161
-
(2006)
Nature
, vol.441
, pp. 1157-1161
-
-
Park, J.1
Lee, S.B.2
Lee, S.3
Kim, Y.4
Song, S.5
Kim, S.6
Bae, E.7
Kim, J.8
Shong, M.9
Kim, J.M.10
Chung, J.11
-
69
-
-
33745589773
-
Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin
-
Clark, I. E., Dodson, M. W., Jiang, C., Cao, J. H., Huh, J. R., Seol, J. H., Yoo, S. J., Hay, B. A., and Guo, M. (2006) Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin. Nature 441, 1162-1166
-
(2006)
Nature
, vol.441
, pp. 1162-1166
-
-
Clark, I.E.1
Dodson, M.W.2
Jiang, C.3
Cao, J.H.4
Huh, J.R.5
Seol, J.H.6
Yoo, S.J.7
Hay, B.A.8
Guo, M.9
-
70
-
-
33746080412
-
Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin
-
Yang, Y., Gehrke, S., Imai, Y., Huang, Z., Ouyang, Y., Wang, J. W., Yang, L., Beal, M. F., Vogel, H., and Lu, B. (2006) Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin. Proc. Natl. Acad. Sci. U. S. A. 103, 10793-10798
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 10793-10798
-
-
Yang, Y.1
Gehrke, S.2
Imai, Y.3
Huang, Z.4
Ouyang, Y.5
Wang, J.W.6
Yang, L.7
Beal, M.F.8
Vogel, H.9
Lu, B.10
-
71
-
-
75949130828
-
PINK1/Parkin-mediated mitophagy is dependent on voltage-dependent anion channel 1 and p62/SQSTM1
-
Geisler, S., Holmström, K. M., Skujat, D., Fiesel, F. C., Rothfuss, O. C., Kahle, P. J., and Springer, W. (2010) PINK1/Parkin-mediated mitophagy is dependent on voltage-dependent anion channel 1 and p62/SQSTM1. Nat. Cell Biol. 12, 119-131
-
(2010)
Nat. Cell Biol.
, vol.12
, pp. 119-131
-
-
Geisler, S.1
Holmström, K.M.2
Skujat, D.3
Fiesel, F.C.4
Rothfuss, O.C.5
Kahle, P.J.6
Springer, W.7
-
72
-
-
84879674444
-
Structure and function of Parkin E3 ubiquitin ligase reveals aspects of RING and HECT ligases
-
Riley, B. E., Lougheed, J. C., Callaway, K., Velasquez, M., Brecht, E., Nguyen, L., Shaler, T., Walker, D., Yang, Y., Regnstrom, K., Diep, L., Zhang, Z., Chiou, S., Bova, M., Artis, D. R., Yao, N., Baker, J., Yednock, T., and Johnston, J. A. (2013) Structure and function of Parkin E3 ubiquitin ligase reveals aspects of RING and HECT ligases. Nat. Commun. 4, 1982
-
(2013)
Nat. Commun.
, vol.4
, pp. 1982
-
-
Riley, B.E.1
Lougheed, J.C.2
Callaway, K.3
Velasquez, M.4
Brecht, E.5
Nguyen, L.6
Shaler, T.7
Walker, D.8
Yang, Y.9
Regnstrom, K.10
Diep, L.11
Zhang, Z.12
Chiou, S.13
Bova, M.14
Artis, D.R.15
Yao, N.16
Baker, J.17
Yednock, T.18
Johnston, J.A.19
-
73
-
-
84879980089
-
A molecular explanation for the recessive nature of parkin-linked Parkinson's disease
-
Spratt, D. E., Julio Martinez-Torres, R., Noh, Y. J., Mercier, P., Manczyk, N., Barber, K. R., Aguirre, J. D., Burchell, L., Purkiss, A., Walden, H., and Shaw, G. S. (2013) A molecular explanation for the recessive nature of parkin-linked Parkinson's disease. Nat. Commun. 4, 1983
-
(2013)
Nat. Commun.
, vol.4
, pp. 1983
-
-
Spratt, D.E.1
Julio Martinez-Torres, R.2
Noh, Y.J.3
Mercier, P.4
Manczyk, N.5
Barber, K.R.6
Aguirre, J.D.7
Burchell, L.8
Purkiss, A.9
Walden, H.10
Shaw, G.S.11
-
74
-
-
84881477223
-
Structure of the human Parkin ligase domain in an autoinhibited state
-
10.1038/emboj.2013.125
-
Wauer, T., and Komander, D. (2013) Structure of the human Parkin ligase domain in an autoinhibited state. EMBO J. 10.1038/emboj.2013.125
-
(2013)
EMBO J.
-
-
Wauer, T.1
Komander, D.2
-
75
-
-
84879885169
-
Parkin mitochondrial translocation is achieved through a novel catalytic activity coupled mechanism
-
Zheng, X., and Hunter, T. (2013) Parkin mitochondrial translocation is achieved through a novel catalytic activity coupled mechanism. Cell Res. 23, 886-897
-
(2013)
Cell Res.
, vol.23
, pp. 886-897
-
-
Zheng, X.1
Hunter, T.2
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