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Volumn 80, Issue 14, 2014, Pages 1161-1170

Natural product libraries: Assembly, maintenance, and screening

Author keywords

extraction; library; natural product; screening; stability

Indexed keywords

BIOLOGICAL PRODUCT; MOLECULAR LIBRARY; PLANT EXTRACT;

EID: 84928893853     PISSN: 00320943     EISSN: 14390221     Source Type: Journal    
DOI: 10.1055/s-0033-1360109     Document Type: Review
Times cited : (42)

References (118)
  • 1
    • 11344292132 scopus 로고    scopus 로고
    • The role of natural product chemistry in drug discovery
    • Butler M. S. The role of natural product chemistry in drug discovery. J Nat Prod: 2004; 67 2141 2153
    • (2004) J Nat Prod , vol.67 , pp. 2141-2153
    • Butler, M.S.1
  • 2
    • 44249098800 scopus 로고    scopus 로고
    • Natural products to drugs: Natural product-derived compounds in clinical trials
    • Butler M. S. Natural products to drugs: natural product-derived compounds in clinical trials. Nat Prod Rep: 2008; 25 475 516
    • (2008) Nat Prod Rep , vol.25 , pp. 475-516
    • Butler, M.S.1
  • 3
    • 84876002671 scopus 로고    scopus 로고
    • Natural products: A continuing source of novel drug leads
    • Cragg G. M., Newman D. J. Natural products: a continuing source of novel drug leads. Biochim Biophys Acta: 2013; 1830 3670 3695
    • (2013) Biochim Biophys Acta , vol.1830 , pp. 3670-3695
    • Cragg, G.M.1    Newman, D.J.2
  • 4
    • 84858308226 scopus 로고    scopus 로고
    • Natural products as sources of new drugs over the 30 years from 1981 to 2010
    • Newman D. J., Cragg G. M. Natural products as sources of new drugs over the 30 years from 1981 to 2010. J Nat Prod: 2012; 75 311 335
    • (2012) J Nat Prod , vol.75 , pp. 311-335
    • Newman, D.J.1    Cragg, G.M.2
  • 5
    • 77953746289 scopus 로고    scopus 로고
    • Drug discovery: Know your chemical space
    • Hopkins A. L., Bickerton G. R. Drug discovery: Know your chemical space. Nat Chem Biol: 2010; 6 482 483
    • (2010) Nat Chem Biol , vol.6 , pp. 482-483
    • Hopkins, A.L.1    Bickerton, G.R.2
  • 6
    • 0033104653 scopus 로고    scopus 로고
    • Statistical investigation into the structural complementarity of natural products and synthetic compounds
    • Henkel T., Brunne R. M., Müller H., Reichel F. Statistical investigation into the structural complementarity of natural products and synthetic compounds. Angew Chem Int Ed: 1999; 38 643 647
    • (1999) Angew Chem Int Ed , vol.38 , pp. 643-647
    • Henkel, T.1    Brunne, R.M.2    Müller, H.3    Reichel, F.4
  • 8
    • 84863825873 scopus 로고    scopus 로고
    • Charting, navigating, and populating natural product chemical space for drug discovery
    • Lachance H., Wetzel S., Kumar K., Waldmann H. Charting, navigating, and populating natural product chemical space for drug discovery. J Med Chem: 2012; 55 5989 6001
    • (2012) J Med Chem , vol.55 , pp. 5989-6001
    • Lachance, H.1    Wetzel, S.2    Kumar, K.3    Waldmann, H.4
  • 9
    • 84866931846 scopus 로고    scopus 로고
    • Lessons from natural products chemistry can offer novel approaches for synthetic chemistry in drug discovery
    • Vasilevich N. I., Kombarov R. V., Genis D. V., Kirpichenok M. A. Lessons from natural products chemistry can offer novel approaches for synthetic chemistry in drug discovery. J Med Chem: 2012; 55 7003 7009
    • (2012) J Med Chem , vol.55 , pp. 7003-7009
    • Vasilevich, N.I.1    Kombarov, R.V.2    Genis, D.V.3    Kirpichenok, M.A.4
  • 10
    • 38449122425 scopus 로고    scopus 로고
    • High impact technologies for natural products screening
    • 177-210
    • Koehn F. E. High impact technologies for natural products screening. Prog Drug Res: 2008; 65 175 177-210
    • (2008) Prog Drug Res , vol.65 , pp. 175
    • Koehn, F.E.1
  • 11
    • 14944383798 scopus 로고    scopus 로고
    • The evolving role of natural products in drug discovery
    • Koehn F. E., Carter G. T. The evolving role of natural products in drug discovery. Nat Rev Drug Discov: 2005; 4 206 220
    • (2005) Nat Rev Drug Discov , vol.4 , pp. 206-220
    • Koehn, F.E.1    Carter, G.T.2
  • 12
    • 84882354548 scopus 로고    scopus 로고
    • From micrograms to grams: Scale-up synthesis of eribulin mesylate
    • Yu M. J., Zheng W., Seletsky B. M. From micrograms to grams: scale-up synthesis of eribulin mesylate. Nat Prod Rep: 2013; 30 1158 1164
    • (2013) Nat Prod Rep , vol.30 , pp. 1158-1164
    • Yu, M.J.1    Zheng, W.2    Seletsky, B.M.3
  • 16
    • 84884126310 scopus 로고    scopus 로고
    • Homoharringtonine/omacetaxine mepesuccinate: The long and winding road to food and drug administration approval
    • Kantarjian H. M., O?Brien S., Cortes J. Homoharringtonine/omacetaxine mepesuccinate: the long and winding road to food and drug administration approval. Clin Lymphoma Myeloma Leuk: 2013; 13 530 533
    • (2013) Clin Lymphoma Myeloma Leuk , vol.13 , pp. 530-533
    • Kantarjian, H.M.1    Obrien, S.2    Cortes, J.3
  • 17
    • 0035289779 scopus 로고    scopus 로고
    • Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
    • Lipinski C. A., Lombardo F., Dominy B. W., Feeney P. J. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. Adv Drug Deliv Rev: 2001; 46 3 26
    • (2001) Adv Drug Deliv Rev , vol.46 , pp. 3-26
    • Lipinski, C.A.1    Lombardo, F.2    Dominy, B.W.3    Feeney, P.J.4
  • 18
    • 44949134801 scopus 로고    scopus 로고
    • The impact of natural products upon modern drug discovery
    • Ganesan A. The impact of natural products upon modern drug discovery. Curr Opin Chem Biol: 2008; 12 306 317
    • (2008) Curr Opin Chem Biol , vol.12 , pp. 306-317
    • Ganesan, A.1
  • 19
    • 34548295338 scopus 로고    scopus 로고
    • Origin and evolution of high throughput screening
    • Pereira D. A., Williams J. A. Origin and evolution of high throughput screening. Br J Pharmacol: 2007; 152 53 61
    • (2007) Br J Pharmacol , vol.152 , pp. 53-61
    • Pereira, D.A.1    Williams, J.A.2
  • 21
    • 84930489603 scopus 로고    scopus 로고
    • Maréchal E. Roy S. Lafanechère L. editors Chemogenomics and chemical genetics: a user?s introduction for biologists, chemists and informaticians Berlin Springer-Verlag
    • Knibiehler M. The miniaturised biological assay: constraints and limitations. In: Maréchal E., Roy S., Lafanechère L. editors Chemogenomics and chemical genetics: a user?s introduction for biologists, chemists and informaticians. Berlin Springer-Verlag: 2011; 29 42
    • (2011) The Miniaturised Biological Assay: Constraints and Limitations , pp. 29-42
    • Knibiehler, M.1
  • 24
    • 84874956949 scopus 로고    scopus 로고
    • Natural product isolation - How to get from biological material to pure compounds
    • Bucar F., Wube A., Schmid M. Natural product isolation - how to get from biological material to pure compounds. Nat Prod Rep: 2013; 30 525 545
    • (2013) Nat Prod Rep , vol.30 , pp. 525-545
    • Bucar, F.1    Wube, A.2    Schmid, M.3
  • 25
  • 27
    • 80052699048 scopus 로고    scopus 로고
    • The extraction of natural products using ultrasound or microwaves
    • Mason T. J., Chemat F., Vinatoru M. The extraction of natural products using ultrasound or microwaves. Curr Org Chem: 2011; 15 237 247
    • (2011) Curr Org Chem , vol.15 , pp. 237-247
    • Mason, T.J.1    Chemat, F.2    Vinatoru, M.3
  • 28
    • 80051862075 scopus 로고    scopus 로고
    • Microwave-assisted extractions of active ingredients from plants
    • Chan C. H., Yusoff R., Ngoh G. C., Kung F. WL. Microwave-assisted extractions of active ingredients from plants. J Chromatogr A: 2011; 1218 6213 6225
    • (2011) J Chromatogr A , vol.1218 , pp. 6213-6225
    • Chan, C.H.1    Yusoff, R.2    Ngoh, G.C.3    Kung, F.W.4
  • 30
    • 77950118235 scopus 로고    scopus 로고
    • Supercritical fluid extraction: Recent advances and applications
    • Herrero M., Mendiola J. A., Cifuentes A., Ibáñez E. Supercritical fluid extraction: Recent advances and applications. J Chromatogr A: 2010; 1217 2495 2511
    • (2010) J Chromatogr A , vol.1217 , pp. 2495-2511
    • Herrero, M.1    Mendiola, J.A.2    Cifuentes, A.3    Ibáñez, E.4
  • 31
    • 84863877697 scopus 로고    scopus 로고
    • Isolation of essential oil from different plants and herbs by supercritical fluid extraction
    • Fornari T., Vicente G., Vázquez E., García-Risco M. R., Reglero G. Isolation of essential oil from different plants and herbs by supercritical fluid extraction. J Chromatogr A: 2012; 1250 34 48
    • (2012) J Chromatogr A , vol.1250 , pp. 34-48
    • Fornari, T.1    Vicente, G.2    Vázquez, E.3    García-Risco, M.R.4    Reglero, G.5
  • 32
    • 84865361070 scopus 로고    scopus 로고
    • Application of ionic liquid for extraction and separation of bioactive compounds from plants
    • Tang B., Bi W., Tian M., Row K. H. Application of ionic liquid for extraction and separation of bioactive compounds from plants. J Chromatogr B: 2012; 904 1 21
    • (2012) J Chromatogr B , vol.904 , pp. 1-21
    • Tang, B.1    Bi, W.2    Tian, M.3    Row, K.H.4
  • 33
    • 84874231758 scopus 로고    scopus 로고
    • Natural deep eutectic solvents as new potential media for green technology
    • Dai Y., van Spronsen J., Witkamp G. J., Verpoorte R., Choi Y. H. Natural deep eutectic solvents as new potential media for green technology. Anal Chim Acta: 2013; 766 61 68
    • (2013) Anal Chim Acta , vol.766 , pp. 61-68
    • Dai, Y.1    Van Spronsen, J.2    Witkamp, G.J.3    Verpoorte, R.4    Choi, Y.H.5
  • 34
    • 84880003478 scopus 로고    scopus 로고
    • Natural deep eutectic solvents as a new extraction media for phenolic metabolites in Carthamus tinctorius L
    • Dai Y., Witkamp G. J., Verpoorte R., Choi Y. H. Natural deep eutectic solvents as a new extraction media for phenolic metabolites in Carthamus tinctorius L. Anal Chem: 2013; 85 6272 6278
    • (2013) Anal Chem , vol.85 , pp. 6272-6278
    • Dai, Y.1    Witkamp, G.J.2    Verpoorte, R.3    Choi, Y.H.4
  • 35
    • 34548279788 scopus 로고    scopus 로고
    • Molecular understanding and modern application of traditional medicines: Triumphs and trials
    • Corson T. W., Crews C. M. Molecular understanding and modern application of traditional medicines: triumphs and trials. Cell: 2007; 130 769 774
    • (2007) Cell , vol.130 , pp. 769-774
    • Corson, T.W.1    Crews, C.M.2
  • 36
    • 84874974106 scopus 로고    scopus 로고
    • 21st Century natural product research and drug development and traditional medicines
    • Ngo L. T., Okogun J. I., Folk W. R. 21st Century natural product research and drug development and traditional medicines. Nat Prod Rep: 2013; 30 584 592
    • (2013) Nat Prod Rep , vol.30 , pp. 584-592
    • Ngo, L.T.1    Okogun, J.I.2    Folk, W.R.3
  • 37
    • 84859831359 scopus 로고    scopus 로고
    • Sarker S.D. Nahar L. editors Natural products isolation Totowa Humana Press
    • Jones W., Kinghorn A. D. Extraction of plant secondary metabolites. In: Sarker S. D., Nahar L. editors Natural products isolation. Totowa Humana Press: 2012; 341 366
    • (2012) Extraction of Plant Secondary Metabolites , pp. 341-366
    • Jones, W.1    Kinghorn, A.D.2
  • 38
    • 0026062445 scopus 로고
    • Evaluation of natural products as inhibitors of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase
    • Tan G. T., Pezzuto J. M., Kinghorn A. D., Hughes S. H. Evaluation of natural products as inhibitors of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase. J Nat Prod: 1991; 54 143 154
    • (1991) J Nat Prod , vol.54 , pp. 143-154
    • Tan, G.T.1    Pezzuto, J.M.2    Kinghorn, A.D.3    Hughes, S.H.4
  • 39
    • 0031873572 scopus 로고    scopus 로고
    • Removal of polyphenolic compounds from aqueous plant extracts using polyamide minicolumns
    • Collins R. A., Ng T. B., Fong W. P., Wan C. C., Yeung H. W. Removal of polyphenolic compounds from aqueous plant extracts using polyamide minicolumns. IUBMB Life: 1998; 45 791 796
    • (1998) IUBMB Life , vol.45 , pp. 791-796
    • Collins, R.A.1    Ng, T.B.2    Fong, W.P.3    Wan, C.C.4    Yeung, H.W.5
  • 41
    • 0034042057 scopus 로고    scopus 로고
    • 10-Hydroxydarlingine, a new tropane alkaloid from the Australian proteaceous plant Triunia erythrocarpa
    • Butler M. S., Katavic P. L., Davis R. A., Forster P. I., Guymer G. P., Quinn R. J. 10-Hydroxydarlingine, a new tropane alkaloid from the Australian proteaceous plant Triunia erythrocarpa. J Nat Prod: 2000; 63 688 689
    • (2000) J Nat Prod , vol.63 , pp. 688-689
    • Butler, M.S.1    Katavic, P.L.2    Davis, R.A.3    Forster, P.I.4    Guymer, G.P.5    Quinn, R.J.6
  • 42
    • 35648967032 scopus 로고    scopus 로고
    • Microtiter plates as mini-bioreactors: Miniaturization of fermentation methods
    • Duetz W. A. Microtiter plates as mini-bioreactors: miniaturization of fermentation methods. Trends Microbiol: 2007; 15 469 475
    • (2007) Trends Microbiol , vol.15 , pp. 469-475
    • Duetz, W.A.1
  • 43
    • 76049095346 scopus 로고    scopus 로고
    • Reducing the variability of antibiotic production in Streptomyces by cultivation in 24-square deepwell plates
    • Siebenberg S., Bapat P. M., Lantz A. E., Gust B., Heide L. Reducing the variability of antibiotic production in Streptomyces by cultivation in 24-square deepwell plates. J Biosci Bioeng: 2010; 109 230 234
    • (2010) J Biosci Bioeng , vol.109 , pp. 230-234
    • Siebenberg, S.1    Bapat, P.M.2    Lantz, A.E.3    Gust, B.4    Heide, L.5
  • 44
    • 79953232687 scopus 로고    scopus 로고
    • Chemical screening method for the rapid identification of microbial sources of marine invertebrate-associated metabolites
    • Berrue F., Withers S. T., Haltli B., Withers J., Kerr R. G. Chemical screening method for the rapid identification of microbial sources of marine invertebrate-associated metabolites. Mar Drugs: 2011; 9 369 381
    • (2011) Mar Drugs , vol.9 , pp. 369-381
    • Berrue, F.1    Withers, S.T.2    Haltli, B.3    Withers, J.4    Kerr, R.G.5
  • 46
    • 84884907545 scopus 로고    scopus 로고
    • Bioactive polyketides isolated from agar-supported fermentation of Phomopsis sp. CMU-LMA, taking advantage of the scale-up device, Platotex
    • Adelin E., Martin M. T., Cortial S., Retailleau P., Lumyong S., Ouazzani J. Bioactive polyketides isolated from agar-supported fermentation of Phomopsis sp. CMU-LMA, taking advantage of the scale-up device, Platotex. Phytochemistry: 2013; 93 170 175
    • (2013) Phytochemistry , vol.93 , pp. 170-175
    • Adelin, E.1    Martin, M.T.2    Cortial, S.3    Retailleau, P.4    Lumyong, S.5    Ouazzani, J.6
  • 48
    • 0036902202 scopus 로고    scopus 로고
    • Big effects from small changes: Possible ways to explore nature?s chemical diversity
    • Bode H. B., Bethe B., Höfs R., Zeeck A. Big effects from small changes: possible ways to explore nature?s chemical diversity. Chem Biochem: 2002; 3 619 627
    • (2002) Chem Biochem , vol.3 , pp. 619-627
    • Bode, H.B.1    Bethe, B.2    Höfs, R.3    Zeeck, A.4
  • 49
    • 73949102298 scopus 로고    scopus 로고
    • Epigenome manipulation as a pathway to new natural product scaffolds and their congeners
    • Cichewicz R. H. Epigenome manipulation as a pathway to new natural product scaffolds and their congeners. Nat Prod Rep: 2010; 27 11 22
    • (2010) Nat Prod Rep , vol.27 , pp. 11-22
    • Cichewicz, R.H.1
  • 51
    • 79960105974 scopus 로고    scopus 로고
    • Small-molecule elicitation of microbial secondary metabolites
    • Pettit R. K. Small-molecule elicitation of microbial secondary metabolites. Microb Biotechnol: 2011; 4 471 478
    • (2011) Microb Biotechnol , vol.4 , pp. 471-478
    • Pettit, R.K.1
  • 52
    • 64549150542 scopus 로고    scopus 로고
    • Triggering cryptic natural product biosynthesis in microorganisms
    • Scherlach K., Hertweck C. Triggering cryptic natural product biosynthesis in microorganisms. Org Biomol Chem: 2009; 7 1753 1760
    • (2009) Org Biomol Chem , vol.7 , pp. 1753-1760
    • Scherlach, K.1    Hertweck, C.2
  • 53
    • 84872353481 scopus 로고    scopus 로고
    • New strategies for drug discovery: Activation of silent or weakly expressed microbial gene clusters
    • Ochi K., Hosaka T. New strategies for drug discovery: activation of silent or weakly expressed microbial gene clusters. Appl Microbiol Biotechnol: 2013; 97 87 98
    • (2013) Appl Microbiol Biotechnol , vol.97 , pp. 87-98
    • Ochi, K.1    Hosaka, T.2
  • 57
    • 34547335884 scopus 로고    scopus 로고
    • A simple method for high-throughput extract prefractionation for biological screening
    • Appleton D. R., Buss A. D., Butler M. S. A simple method for high-throughput extract prefractionation for biological screening. Chimia: 2007; 61 327 331
    • (2007) Chimia , vol.61 , pp. 327-331
    • Appleton, D.R.1    Buss, A.D.2    Butler, M.S.3
  • 58
    • 46749090589 scopus 로고    scopus 로고
    • Pre-fractionated microbial samples - The second generation natural products library at Wyeth
    • Wagenaar M. M. Pre-fractionated microbial samples - the second generation natural products library at Wyeth. Molecules: 2008; 13 1406 1426
    • (2008) Molecules , vol.13 , pp. 1406-1426
    • Wagenaar, M.M.1
  • 59
    • 46749120720 scopus 로고    scopus 로고
    • Fractionated marine invertebrate extract libraries for drug discovery
    • Bugni T. S., Harper M. K., McCulloch M. WB, Reppart J., Ireland C. M. Fractionated marine invertebrate extract libraries for drug discovery. Molecules: 2008; 13 1372 1383
    • (2008) Molecules , vol.13 , pp. 1372-1383
    • Bugni, T.S.1    Harper, M.K.2    McCulloch, M.W.3    Reppart, J.4    Ireland, C.M.5
  • 62
    • 84856449974 scopus 로고    scopus 로고
    • Drug-like properties: Guiding principles for the design of natural product libraries
    • Camp D., Davis R. A., Campitelli M., Ebdon J., Quinn R. J. Drug-like properties: guiding principles for the design of natural product libraries. J Nat Prod: 2011; 75 72 81
    • (2011) J Nat Prod , vol.75 , pp. 72-81
    • Camp, D.1    Davis, R.A.2    Campitelli, M.3    Ebdon, J.4    Quinn, R.J.5
  • 63
    • 84876108510 scopus 로고    scopus 로고
    • Front-loading natural-product-screening libraries for log P: Background, development, and implementation
    • Camp D., Campitelli M., Carroll A. R., Davis R. A., Quinn R. J. Front-loading natural-product-screening libraries for log P: background, development, and implementation. Chem Biodivers: 2013; 10 524 537
    • (2013) Chem Biodivers , vol.10 , pp. 524-537
    • Camp, D.1    Campitelli, M.2    Carroll, A.R.3    Davis, R.A.4    Quinn, R.J.5
  • 64
    • 0029079739 scopus 로고
    • Rapid identification of elaiophylin and geldanamycin in Streptomyces fermentation broths using CPC coupled with a photodiode array detector and LC-MS methodologies
    • Alvi K. A., Peterson J., Hofmann B. Rapid identification of elaiophylin and geldanamycin in Streptomyces fermentation broths using CPC coupled with a photodiode array detector and LC-MS methodologies. J Indian Microbiol: 1995; 15 80 84
    • (1995) J Indian Microbiol , vol.15 , pp. 80-84
    • Alvi, K.A.1    Peterson, J.2    Hofmann, B.3
  • 66
    • 0033841529 scopus 로고    scopus 로고
    • Application of centrifugal partition chromatography in a general separation and dereplication procedure for plant extracts
    • Ingkaninan K., Hazekamp A., Hoek A. C., Balconi S., Verpoorte R. Application of centrifugal partition chromatography in a general separation and dereplication procedure for plant extracts. J Liq Chromatogr Relat Technol: 2000; 23 2195 2208
    • (2000) J Liq Chromatogr Relat Technol , vol.23 , pp. 2195-2208
    • Ingkaninan, K.1    Hazekamp, A.2    Hoek, A.C.3    Balconi, S.4    Verpoorte, R.5
  • 70
    • 34547380174 scopus 로고    scopus 로고
    • Burning the hay to find the needle - Data mining strategies in natural product dereplication
    • Wolf D., Siems K. Burning the hay to find the needle - data mining strategies in natural product dereplication. Chimia: 2007; 61 339 345
    • (2007) Chimia , vol.61 , pp. 339-345
    • Wolf, D.1    Siems, K.2
  • 73
    • 84861179772 scopus 로고    scopus 로고
    • Microbial strain prioritization using metabolomics tools for the discovery of natural products
    • Hou Y., Braun D. R., Michel C. R., Klassen J. L., Adnani N., Wyche T. P., Bugni T. S. Microbial strain prioritization using metabolomics tools for the discovery of natural products. Anal Chem: 2012; 84 4277 4283
    • (2012) Anal Chem , vol.84 , pp. 4277-4283
    • Hou, Y.1    Braun, D.R.2    Michel, C.R.3    Klassen, J.L.4    Adnani, N.5    Wyche, T.P.6    Bugni, T.S.7
  • 74
  • 76
    • 84862319381 scopus 로고    scopus 로고
    • Implementing best practices and validation of cryopreservation techniques for microorganisms
    • Smith D., Ryan M. Implementing best practices and validation of cryopreservation techniques for microorganisms. Scientific World J: 2012; 2012 805659
    • (2012) Scientific World J , vol.2012 , pp. 805659
    • Smith, D.1    Ryan, M.2
  • 77
    • 26244468507 scopus 로고    scopus 로고
    • Bio-banking in microbiology: From sample collection to epidemiology, diagnosis and research
    • De Paoli P. Bio-banking in microbiology: from sample collection to epidemiology, diagnosis and research. FEMS Microbiol Rev: 2005; 29 897 910
    • (2005) FEMS Microbiol Rev , vol.29 , pp. 897-910
    • De Paoli, P.1
  • 83
    • 34247526874 scopus 로고    scopus 로고
    • Establishment of an open access compound management facility in Australia to stimulate applied, basic and translational biomedical research
    • Camp D. Establishment of an open access compound management facility in Australia to stimulate applied, basic and translational biomedical research. Drug Discov World: 2007; 2007 61 66
    • (2007) Drug Discov World , vol.2007 , pp. 61-66
    • Camp, D.1
  • 84
    • 67449108090 scopus 로고    scopus 로고
    • Achieving accurate compound concentration in cell-based screening: Validation of acoustic droplet ejection technology
    • Grant R. J., Roberts K., Pointon C., Hodgson C., Womersley L., Jones D. C., Tang E. Achieving accurate compound concentration in cell-based screening: validation of acoustic droplet ejection technology. J Biomol Screen: 2009; 14 452 459
    • (2009) J Biomol Screen , vol.14 , pp. 452-459
    • Grant, R.J.1    Roberts, K.2    Pointon, C.3    Hodgson, C.4    Womersley, L.5    Jones, D.C.6    Tang, E.7
  • 85
    • 84930492210 scopus 로고    scopus 로고
    • Buss A.D. Butler M.S. editors Natural product chemistry for drug discovery London The Royal Society of Chemistry
    • Parker C. N., Ottl J., Gabriel D., Zhang J. H. Advances in biological screening for lead discovery. In: Buss A. D., Butler M. S. editors Natural product chemistry for drug discovery. London The Royal Society of Chemistry: 2009; 243 271
    • (2009) Advances in Biological Screening for Lead Discovery , pp. 243-271
    • Parker, C.N.1    Ottl, J.2    Gabriel, D.3    Zhang, J.H.4
  • 89
    • 79961195711 scopus 로고    scopus 로고
    • High-throughput screening of Australian marine organism extracts for bioactive molecules affecting the cellular storage of neutral lipids
    • Rae J., Fontaine F., Salim A. A., Lo H. P., Capon R. J., Parton R. G., Martin S. High-throughput screening of Australian marine organism extracts for bioactive molecules affecting the cellular storage of neutral lipids. PLoS One: 2011; 6 e22868
    • (2011) PLoS One , vol.6 , pp. e22868
    • Rae, J.1    Fontaine, F.2    Salim, A.A.3    Lo, H.P.4    Capon, R.J.5    Parton, R.G.6    Martin, S.7
  • 90
    • 77954618528 scopus 로고    scopus 로고
    • Heterofibrins: Inhibitors of lipid droplet formation from a deep-water southern Australian marine sponge, Spongia (Heterofibria) sp
    • Salim A. A., Rae J., Fontaine F., Conte M. M., Khalil Z., Martin S., Parton R. G., Capon R. J. Heterofibrins: inhibitors of lipid droplet formation from a deep-water southern Australian marine sponge, Spongia (Heterofibria) sp. Org Biomol Chem: 2010; 8 3188 3194
    • (2010) Org Biomol Chem , vol.8 , pp. 3188-3194
    • Salim, A.A.1    Rae, J.2    Fontaine, F.3    Conte, M.M.4    Khalil, Z.5    Martin, S.6    Parton, R.G.7    Capon, R.J.8
  • 91
    • 77954748537 scopus 로고    scopus 로고
    • Physiological roles of ion channels in adult neural stem cells and their progeny
    • Yasuda T., Adams D. J. Physiological roles of ion channels in adult neural stem cells and their progeny. J Neurochem: 2010; 114 946 959
    • (2010) J Neurochem , vol.114 , pp. 946-959
    • Yasuda, T.1    Adams, D.J.2
  • 93
    • 33746789921 scopus 로고    scopus 로고
    • Quantitative high-throughput screening: A titration-based approach that efficiently identifies biological activities in large chemical libraries
    • Inglese J., Auld D. S., Jadhav A., Johnson R. L., Simeonov A., Yasgar A., Zheng W., Austin C. P. Quantitative high-throughput screening: A titration-based approach that efficiently identifies biological activities in large chemical libraries. Proc Natl Acad Sci U S A: 2006; 103 11473 11478
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 11473-11478
    • Inglese, J.1    Auld, D.S.2    Jadhav, A.3    Johnson, R.L.4    Simeonov, A.5    Yasgar, A.6    Zheng, W.7    Austin, C.P.8
  • 97
    • 0021139131 scopus 로고
    • Fluorimetric determination of critical micelle concentration avoiding interference from detergent charge
    • Chattopadhyay A., London E. Fluorimetric determination of critical micelle concentration avoiding interference from detergent charge. Anal Biochem: 1984; 139 408 412
    • (1984) Anal Biochem , vol.139 , pp. 408-412
    • Chattopadhyay, A.1    London, E.2
  • 98
    • 33745188660 scopus 로고    scopus 로고
    • Screening in a spirit haunted world
    • Shoichet B. K. Screening in a spirit haunted world. Drug Discov Today: 2006; 11 607 615
    • (2006) Drug Discov Today , vol.11 , pp. 607-615
    • Shoichet, B.K.1
  • 99
    • 77952545106 scopus 로고    scopus 로고
    • Apparent activity in high-throughput screening: Origins of compound-dependent assay interference
    • Thorne N., Auld D. S., Inglese J. Apparent activity in high-throughput screening: origins of compound-dependent assay interference. Curr Opin Chem Biol: 2010; 14 315 324
    • (2010) Curr Opin Chem Biol , vol.14 , pp. 315-324
    • Thorne, N.1    Auld, D.S.2    Inglese, J.3
  • 100
    • 64549152003 scopus 로고    scopus 로고
    • Promiscuous aggregate-based inhibitors promote enzyme unfolding
    • Coan K. ED, Maltby D. A., Burlingame A. L., Shoichet B. K. Promiscuous aggregate-based inhibitors promote enzyme unfolding. J Med Chem: 2009; 52 2067 2075
    • (2009) J Med Chem , vol.52 , pp. 2067-2075
    • Coan, K.E.1    Maltby, D.A.2    Burlingame, A.L.3    Shoichet, B.K.4
  • 101
    • 79953137976 scopus 로고    scopus 로고
    • Non-stoichiometric inhibition in biochemical high-throughput screening
    • Coan K. E., Ottl J., Klumpp M. Non-stoichiometric inhibition in biochemical high-throughput screening. Expert Opin Drug Discov: 2011; 6 405 417
    • (2011) Expert Opin Drug Discov , vol.6 , pp. 405-417
    • Coan, K.E.1    Ottl, J.2    Klumpp, M.3
  • 102
    • 84875733971 scopus 로고    scopus 로고
    • Colloidal aggregation causes inhibition of G protein-coupled receptors
    • Sassano M. F., Doak A. K., Roth B. L., Shoichet B. K. Colloidal aggregation causes inhibition of G protein-coupled receptors. J Med Chem: 2013; 56 2406 2414
    • (2013) J Med Chem , vol.56 , pp. 2406-2414
    • Sassano, M.F.1    Doak, A.K.2    Roth, B.L.3    Shoichet, B.K.4
  • 108
    • 0030919897 scopus 로고    scopus 로고
    • Fluorescent chemosensors for divalent zinc based on zinc finger domains. Enhanced oxidative stability, metal binding affinity, and structural and functional characterization
    • Walkup G. K., Imperiali B. Fluorescent chemosensors for divalent zinc based on zinc finger domains. Enhanced oxidative stability, metal binding affinity, and structural and functional characterization. J Am Chem Soc: 1997; 119 3443 3450
    • (1997) J Am Chem Soc , vol.119 , pp. 3443-3450
    • Walkup, G.K.1    Imperiali, B.2
  • 109
    • 84861633463 scopus 로고    scopus 로고
    • Identification of aluminium dioxalate in fungal cultures grown on vermiculite
    • Butler M. S., Yoganathan K., Buss A. D., Ng S. Identification of aluminium dioxalate in fungal cultures grown on vermiculite. J Antibiot: 2012; 65 275 276
    • (2012) J Antibiot , vol.65 , pp. 275-276
    • Butler, M.S.1    Yoganathan, K.2    Buss, A.D.3    Ng, S.4
  • 110
    • 80054882118 scopus 로고    scopus 로고
    • Kinase inhibitors from marine sponges
    • Skropeta D., Pastro N., Zivanovic A. Kinase inhibitors from marine sponges. Mar Drugs: 2011; 9 2131 2154
    • (2011) Mar Drugs , vol.9 , pp. 2131-2154
    • Skropeta, D.1    Pastro, N.2    Zivanovic, A.3
  • 111
    • 0023954781 scopus 로고
    • Results of a large scale screen of microalgae for the production of protease inhibitors
    • Cannell R. J., Kellam S. J., Owsianka A. M., Walker J. M. Results of a large scale screen of microalgae for the production of protease inhibitors. Planta Med: 1988; 54 10 14
    • (1988) Planta Med , vol.54 , pp. 10-14
    • Cannell, R.J.1    Kellam, S.J.2    Owsianka, A.M.3    Walker, J.M.4
  • 112
    • 84879474633 scopus 로고    scopus 로고
    • Protease inhibitors from marine venomous animals and their counterparts in terrestrial venomous animals
    • Mourao C. B., Schwartz E. F. Protease inhibitors from marine venomous animals and their counterparts in terrestrial venomous animals. Mar Drugs: 2013; 11 2069 2112
    • (2013) Mar Drugs , vol.11 , pp. 2069-2112
    • Mourao, C.B.1    Schwartz, E.F.2
  • 113
    • 0033003760 scopus 로고    scopus 로고
    • A simple statistical parameter for use in evaluation and validation of high throughput screening assays
    • Zhang J. H., Chung T. DY, Oldenburg K. R. A simple statistical parameter for use in evaluation and validation of high throughput screening assays. J Biomol Screen: 1999; 4 67 73
    • (1999) J Biomol Screen , vol.4 , pp. 67-73
    • Zhang, J.H.1    Chung, T.D.2    Oldenburg, K.R.3
  • 114
    • 0036247835 scopus 로고    scopus 로고
    • Considerations for using fluorescence polarization in the screening of G protein-coupled receptors
    • Banks P., Harvey M. Considerations for using fluorescence polarization in the screening of G protein-coupled receptors. J Biomol Screen: 2002; 7 111 117
    • (2002) J Biomol Screen , vol.7 , pp. 111-117
    • Banks, P.1    Harvey, M.2
  • 117
    • 38449122425 scopus 로고    scopus 로고
    • Petersen F. Amstutz R. editors Natural compounds as drugs, Volume I Basel Birkhäuser Basel
    • Koehn F. High impact technologies for natural products screening. In: Petersen F., Amstutz R. editors Natural compounds as drugs, Volume I. Basel Birkhäuser Basel: 2008; 175 210
    • (2008) High Impact Technologies for Natural Products Screening , pp. 175-210
    • Koehn, F.1


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